Chii Chinonzi Chronic Lymphocytic Leukemia? Zviratidzo, Zvinokonzera, & Kurapa

Chronic lymphocytic leukemia (CLL), rudzi rwekenza yeropa inokanganisa masero machena eropa anonzi lymphocytes. Aya masero anowanzo kubatsira mukurwisa hutachiona, asi muCLL, anokura zvisina kujairika uye anoungana muropa rako, mumapfupa, uye mu lymph nodes.

Kusiyana nemamwe marudzi e leukemia, CLL inowanzo kuitika zvishoma nezvishoma kwemwedzi kana makore. Vanhu vazhinji vanorarama nechirwere ichi kwemakore mazhinji, uye vamwe vangasamboda kurapwa zvachose. Kunzwisisa CLL kunogona kukubatsira kunzwa wakagadzirira uye usazvidya mwoyo nezviri mberi.

Chii Chinonzi Chronic Lymphocytic Leukemia?

CLL inoitika kana mapfupa ako akaita masero akawanda asingawanzo B-lymphocytes, rudzi rwakasiyana rwe masero machena eropa. Aya masero asina kunaka haakwanisi kurwisa hutachiona zvakanaka uye anodzvinyirira masero eropa ane hutano.

Shoko rokuti "chronic" rinoreva kuti rinofambira mberi zvishoma nezvishoma, izvo zviri nhau dzakanaka. Vanhu vakawanda vane CLL vanogona kuchengetedza hupenyu hwavo hwakajairika kwemakore mazhinji. Chirwere ichi chinonyanya kukanganisa vakuru vakwegura, nevakawanda vachirwara mushure memakore 55.

CLL ndiyo yakajairika leukemia muvakuru munyika dzekuMadokero. Yakasiyana ne acute leukemias, dzinoitika nekukurumidza uye dzinoda kurapwa nekukurumidza.

Ndeapi Zviratidzo zve Chronic Lymphocytic Leukemia?

Vanhu vazhinji vane CLL iri pakutanga havaone zviratidzo zvachose. Chirwere ichi chinowanzoonekwa pakuongororwa kweropa usati waona zviratidzo zvechokuonekwa.

Kana zviratidzo zvikaonekwa, zvinowanzoonekwa zvishoma nezvishoma sezvo masero asingawanzo kuunganidzwa mumuviri wako. Heano mamwe ezviratidzo zvinofanira kutarwa:

• Lymph nodes dzakazvimba pamutsipa wako, pazasi pemabvi, kana muhudyu dzisingarwadzi
• Kunzwa kuneta kana kushaya simba, kunyangwe wakazorora zvakakwana
• Kuwanzo kurwara kunotora nguva yakareba kupora kupfuura zvakajairwa
• Kurasikirwa nehuremu pasina chikonzero kwemwedzi yakati wandei
• Kusveta usiku kunonetesa nguo dzako kana mubhedha
• Kuropwa nyore kana kubuda ropa kubva pakukuvadzwa kwakaderera
• Kunzwa wakazara nekukurumidza paunodya nekuda kwe spleen yakakura
• Kushaya mweya pakuita mabasa akajairika

Zviratidzo zvisingawanzoitiki zvinogona kusanganisira fivha isina chikonzero chakajeka kana kurwadziwa mudumbu. Yeuka, izvi zviratidzo zvinogona kunge zvine zvinokonzera zvakawanda, saka kuva nazvo hazvirevi kuti une CLL.

Ndeapi Marudzi e Chronic Lymphocytic Leukemia?

Vanachiremba vanokamura CLL mune marudzi akasiyana zvichienderana nekuti masero ekenza anoita sei pasi pemikroskopu uye mapuroteni aanotakura. Kusiyana kukuru kuri pakati peCLL yakajairwa nemamwe mamiriro akafanana.

CLL yakajairwa inoumba anenge 95% ezviitiko uye inosanganisira B-lymphocytes. Kunewo rudzi runonzi prolymphocytic leukemia, runowanzo fambira mberi nekukurumidza asi rinowanikwa zvishoma.

Timu yako yekurapa inogona kutaurawo kana masero ako eCLL aine shanduko dzemajini. Mamwe marudzi anokura zvishoma, nepo mamwe achida kurapwa nekukurumidza. Aya mashoko anobatsira chiremba wako kugadzira chirongwa chekurapa chakanaka chakakodzera mamiriro ako chaiwo.

Chii Chinokonzera Chronic Lymphocytic Leukemia?

Chikonzero chaicho cheCLL hachizivisike zvizere, asi chinoitika kana shanduko dzeDNA dzikaitika mu B-lymphocytes. Aya ma mutations emajini anoita kuti masero akure asingadzoreki uye ararame kwenguva refu kupfuura zvavanofanira.

Kazhinji kazhinji zvinoitika pasina chikonzero chakajeka. Hazvikonzerwi nechinhu chawakaita kana kusaita. Kusiyana nemamwe marudzi ekenza, CLL haina hukama nekusvuta, kudya, kana mararamiro.

Zvinhu zvakati wandei zvinogona kuita kuti CLL iitike, kunyangwe hapana chimwe chinokuvimbisa kuti uchawana chirwere ichi:

• Zera - vanhu vakawanda vanorwara vane makore anopfuura 55
• Rudzi - varume vanowanzoita CLL kaviri kupfuura vakadzi
• Nhoroondo yemhuri - kuva nehama dzine CLL kana mamwe marudzi ekenza yeropa kunowedzera njodzi
• Rudzi - CLL yakajairika muvanhu vekuEurope
• Kuonana nemakemikari akati wandei senge Agent Orange (zvishoma)

Kuva nezvinhu izvi zvinowedzera njodzi hazvirevi kuti uchawana CLL. Vanhu vazhinji vane zvinhu zvakawanda zvinowedzera njodzi havasati vawana chirwere ichi, nepo vamwe vasina njodzi yakajeka vachiwana.

Rini Unofanira Kuona Chiremba Nekuda kwe Chronic Lymphocytic Leukemia?

Unofanira kubata chiremba wako kana ukaona zviratidzo zvinoramba zvichiitika kwemavhiki anopfuura mashoma. Kunyangwe izvi zviratidzo zvichine zvinokonzera zvisina ngozi, zviri nani nguva dzose kuzviongorora.

Rongedza nguva yekuona chiremba kana uine lymph nodes dzakazvimba dzisingaperi mushure memavhiki maviri, kunyanya kana dzisingarwadzi. Tsvakawo rubatsiro rwekurapa nekuda kwekuneta kunoramba kuripo kusingaperi nezvirimwa kana kuwanda kwehutachiona.

Usamirira kana uine zviratidzo zvinotyisa senge kurasikirwa nehuremu pasina chikonzero, kusveta usiku kunoramba kuripo, kana kuropwa nyore. Kuonekwa pakutanga kunowanzoita kuti zvibudirire zvakanaka, kunyangwe CLL inowanzo fambira mberi zvishoma nezvishoma.

Ndeapi Zvinhu Zvinowedzera Njodzi ye Chronic Lymphocytic Leukemia?

Zvinhu zvakati wandei zvinogona kuwedzera mikana yako yekuwana CLL, kunyangwe kuva nezvinhu zvinowedzera njodzi hazvirevi kuti uchawana chirwere ichi. Kunzwisisa izvi kunogona kukubatsira kuramba uchiri kuziva pasina kunetseka zvakanyanya.

Zera ndiro chinhu chikuru chinowedzera njodzi. CLL haina kukanganisa vanhu vane makore pasi pe40, uye njodzi yako inowedzera zvakanyanya mushure memakore 55. Vanhu vakawanda vanorwara vane makore 60 kana 70.

Heano mamwe ezvinhu zvikuru zvinowedzera njodzi zvakazivikanwa nevanachiremba:

• Kuva murume - varume vanowanzoita CLL kaviri kupfuura vakadzi
• Kuva nenhoroondo yemhuri yeCLL kana mamwe marudzi ekenza yeropa
• Kuva weAshkenazi Jewish descent
• Kuonana nemakemikari akati wandei kana mwaranzi kare
• Kuva nemamwe matambudziko ehutano hwekuzvidzivirira

Mamwe marudzi asingaawanzoitiki emajini anowedzerawo njodzi yeCLL, asi aya anoita chikamu chidiki chaizvo chezviitiko. Vanhu vakawanda vane CLL havaoneki nenhoroondo yemhuri yechirwere ichi.

Ndeapi Matambudziko Anogona Kuitika e Chronic Lymphocytic Leukemia?

Kunyangwe CLL inowanzo fambira mberi zvishoma nezvishoma, inogona dzimwe nguva kuita matambudziko anoda kurapwa. Kunzwisisa izvi zvinogona kukubatsira kuziva kana uchifanira kutsvaka kurapwa nekukurumidza.

Matambudziko akajairika anoitika nekuti masero eCLL anodzvinyirira masero eropa ane hutano. Izvi zvinogona kukugadzirira kurwara uye kunonoka kupora kubva kukuvara.

Heano mamwe matambudziko anogona kuitika aunofanira kuziva:

• Kuwedzera kwenjodzi yekurwara nekuda kwekuora simba kwekuzvidzivirira
• Anemia inokonzera kuneta kwakanyanya nekushaya simba
• Kuora kwehuwandu hwemapurasiti inokonzera kuropwa nyore kana kubuda ropa
• Spleen yakakura inokonzera kurwadziwa mudumbu
• Kushanduka kuita lymphoma ine utsinye (zvishoma)
• Kuita mamwe marudzi ekenza gare gare muhupenyu
• Matambudziko ekuzvidzivirira apo muviri wako unorwisa masero ane hutano

Richter's transformation, apo CLL inoshanduka kuita lymphoma ine utsinye, inoitika muvanhu vanenge 3-10%. Kunyangwe iri yakakomba, iyi nyaya inogona kurapwa zvakakwana kana yakawanikwa pakutanga.

Chronic Lymphocytic Leukemia Inozwi Sei?

Kuziva CLL kunowanzo tanga nekuongororwa kweropa kunoratidza huwandu husina kujairika hwe masero machena eropa. Chiremba wako achaodza mamwe bvunzo kuti aone kuti chirwere ichi chiripo uye kuti chakafambira mberi sei.

Bvunzo huru yekuziva ndeyonzi flow cytometry, iyo inoziva mapuroteni akasiyana-siyana pamasero eropa ako. Iyi bvunzo inogona kusiyanisa masero eCLL kubva kune mamwe marudzi e lymphocytes nemazvo.

Timu yako yekurapa inogona kukurudzira bvunzo dzakati wandei kuti uwane ruzivo rwakakwana:

• Kuverenga kwakakwana kweropa kuongorora marudzi ose emasero eropa
• Flow cytometry kuziva zviratidzo zveCLL
• Kuongororwa kwemajini kutsvaga shanduko dzechromosomal
• CT scans kuongorora saizi ye lymph nodes
• Bone marrow biopsy (dzimwe nguva inodiwa)
• Immunoglobulin levels kuongorora basa rekuzvidzivirira

Aya ma bvunzo anobatsira chiremba wako kuisa CLL yako uye kuronga nzira yakanaka yekurapa. Kuisa kunokuudza kuti kenza yakapararira sei uye kunobatsira kufanotaura kuti ingaita sei.

Kurapa kwe Chronic Lymphocytic Leukemia Kuita Sei?

Kurapa kweCLL kunotsamira pane nhanho yako, zviratidzo, uye hutano hwako hwese. Vanhu vazhinji vane CLL iri pakutanga havadi kurapwa nekukurumidza uye vanogona kutarwa nekuongororwa kwenguva dzose.

Iyi "tarisa uye mirira" nzira inogona kunzwa inotyisa, asi chaizvoizvo ndiyo nzira yakanaka kwazvo kune vanhu vazhinji. Kutanga kurapwa nekukurumidza hazviwedzere zvibudiriro uye zvinogona kukonzera matambudziko asingakoshi.

Kana kurapwa kuchidiwa, une sarudzo dzakawanda dzinoshanda:

• Mishonga inorwisa mapuroteni chaiwo ekenza
• Immunotherapy kubatsira sisitimu yako yekuzvidzivirira kurwisa kenza
• Chemotherapy, kazhinji inosanganiswa nemamwe marapirwo
• Monoclonal antibodies inorwisa masero eCLL
• Stem cell transplant kune vechidiki vane chirwere chine utsinye
• Radiation therapy kune lymph nodes dzakakura (dzimwe nguva)

Mishonga mitsva yakatarwa senge ibrutinib ne venetoclax yakachinja kurapwa kweCLL. Aya mishonga inowanzo shanda zvakanaka kupfuura chemotherapy yakajairwa ine matambudziko mashoma.

Nzira Yekudzora Zviratidzo Pamba Panguva ye Chronic Lymphocytic Leukemia?

Kudzorera CLL pamba kunotarisa pakutsigira hutano hwako hwese uye kudzivirira hutachiona. Sarudzo diki dzuva nezuva dzinogona kuita musiyano mukuru pane mafungiro ako.

Sezvo CLL ichikanganisa sisitimu yako yekuzvidzivirira, kudzivirira hutachiona kunova chinhu chakakosha. Geza maoko ako kazhinji uye dzivisa kuunganidzwa kwevanhu panguva yechando nechirwere chemafivha kana zvichibvira.

Heano matanho aunogona kutora pamba:

• Dya kudya kwakakwana kwakazara nemiriwo, miriwo, uye mapuroteni asina mafuta
• Ramba uine mvura yakakwana nekudya mvura yakawanda zuva rese
• Zorora zvakakwana kuti utsigire sisitimu yako yekuzvidzivirira
• Ita maekisesaizi zvishoma nezvishoma sezvaunokwanisa kuti uchengetedze simba
• Dzidzira kudzora kushushikana kuburikidza nekufungisisa kana kuzorora
• Ramba uchiita majekiseni akakurudzirwa
• Tarisa tembiricha yako uye uudze fivha nekukurumidza

Teerera kumuviri wako uye zorora kana uchida. Kuneta kwakajairika neCLL, uye kuzvipindira zvakanyanya kunogona kuwedzera zviratidzo.

Ungagadzirira Sei Kune Nguva Yako Yekuona Chiremba?

Kuagadzirira nguva yako yekuona chiremba kunogona kukubatsira kuti uwane zvakawanda kubva panguva yako netimu yako yekurapa. Nyora mibvunzo yako usati watanga kuti usakanganwa zvinhu zvakakosha.

Uyisa runyorwa rwemishonga yose yaunotora, kusanganisira zvinowedzerwa nemishonga yekutengesa. Unganidzawo chero bvunzo dzawakaita kare kana rekodhi dzekurapa dzine hukama nechirwere chako.

Funga kuuya neshamwari yakavimbika kana nhengo yemhuri kuti ikubatsire kuyeuka ruzivo uye kupa rutsigiro rwemanzwiro. Kuva nemunhu mumwe chete kunogona kubatsira zvikuru pakurukura sarudzo dzakaoma dzekurapa.

Gadzira zvinhu izvi kuti uende kunochirapa:

• Runyorwa rwezviratidzo zviripo uye pavakatanga
• Mishonga yose, mavhitamini, nezvinowedzerwa zvaunotora
• Nhoroondo yemhuri ye kenza kana matambudziko eropa
• Mhedzisiro yebvunzo dzawakaita kare kana kuongororwa kwemuviri
• Ruzivo rweinshurensi uye chiratidzo
• Mibvunzo yakanyorwa nezvechirwere chako ne kurapwa

Usazengurire kukumbira kuti ujekeswe kana usinganzwisisi chimwe chinhu. Timu yako yekurapa inoda kuve nechokwadi chekuti unonzwa wakaziva uye wakasununguka nechirongwa chako chekurapa.

Chii Chinonyanya Kukosha Nezve Chronic Lymphocytic Leukemia?

CLL kazhinji inogona kudzorwa uye vanhu vazhinji vanorarama nayo kwemakore mazhinji pasina kukanganisa hupenyu hwavo hwemazuva ese. Kunyangwe kuwana chirwere chekenza kunonzwa kuchinetesa, yeuka kuti CLL inowanzo fambira mberi zvishoma nezvishoma.

Vanhu vazhinji vane CLL vanoramba vachishanda, vachifamba, uye vachifarira zviitiko zvavo zvakajairwa. Kurapa kwazvino kwakanyanya kushanda uye kune matambudziko mashoma kupfuura kare.

Chinhu chakakosha ndechekuchengetedza kutaurirana kwakavhurika netimu yako yekurapa uye kutevera mazano avo ekutarisa ne kurapa. Nekurapa kwakakodzera, vanhu vazhinji vane CLL vanogona kutarisira kurarama hupenyu hwakazara, hunoshanda.

Mibvunzo Inowanzo Kubvunzwa Nezve Chronic Lymphocytic Leukemia

Chronic lymphocytic leukemia inorapika here?

CLL haisi ikozvino inorapika, asi inowanzo kurapika uye inogona kudzorwa. Vanhu vazhinji vanorarama hupenyu hwenguva refu nechirwere ichi. Kurapa kwazvino kuri kuramba kuchivandudza zvibudiriro, uye vatsvakurudzi vari kushanda kuti vawane kurapa kuri nani kunogona rimwe zuva kuita kuti chirwere ichi chirape.

Chronic lymphocytic leukemia inofambira mberi nekukurumidza sei?

CLL inowanzo fambira mberi zvishoma nezvishoma kwemakore kana kunyange makore mazhinji. Vamwe vanhu havadi kurapwa, nepo vamwe vachida kurapwa mushure memakore mazhinji ekutarisa. Chiremba wako anogona kuverenga zvaunotarisira zvichienderana nekuongororwa kwemajini nezvimwe zvinhu.

Unogona kurarama hupenyu hwakajairwa ne chronic lymphocytic leukemia here?

Hongu, vanhu vazhinji vane CLL vanoramba vachirarama hupenyu hunoshanda, hunogutsa. Ungada kutora matanho ekudzivirira hutachiona uye kuenda kuongororo dzemazuva ese, asi zviitiko zvakawanda zvemazuva ese zvinogona kuramba zvichienderera mberi sezvakajairwa. Kurapa, kana kuchidiwa, kazhinji kunobvumira vanhu kuchengetedza hupenyu hwavo hwakajairika.

Ndeapi zvokudya zvandofanira kudzivisa ne chronic lymphocytic leukemia?

Hapana zvokudya zvakakosha zvaunofanira kudzivisa neCLL, asi tarisa kudya zvakachengeteka kudzivirira hutachiona. Dzivisa nyama isina kubikwa kana isina kubikwa zvakanaka, michero nemiriwo isina kushambwa, uye zvigadzirwa zvemukaka zvisina kupasitiriziwa. Kudya kwakakwana, kwakakwana kunotsigira sisitimu yako yekuzvidzivirira nehutano hwese.

Chronic lymphocytic leukemia inogona kuwanikwa kubva kumhuri here?

CLL ine chikamu chemajini, sezvo ichimhanya mumhuri kupfuura mamwe marudzi ekenza. Nekudaro, vanhu vazhinji vane CLL havaoneki nenhoroondo yemhuri yechirwere ichi. Kuva nehama ine CLL kunowedzera njodzi yako, asi hazvirevi kuti uchawana chirwere ichi.