Kukanganiswa Kwema antibodies Enyika (CVID): Zviratidzo, Zvinokonzera, Kurapa

Kukanganiswa kwema antibodies enyika (CVID) chirwere umo masimba ako emuviri asingagadzire ma antibodies akakwana kurwisa hutachiona zvakakwana. Fungidzira ma antibodies sevarindi vekuchengetedza muviri wako vanozivisa uye vanorwisa zvinhu zvinokuvadza senge mabhakitiriya nemavhairasi.

Chirwere ichi chinotapura vanhu vanenge 1 pavagumi nemazana maviri nemazana mashanu, zvichiita kuti chive chirwere chakakomba chekushomeka kwemasimba emuviri chinoonekwa nevanachiremba kuvanyoro vakuru. Kunyange zvazvo zvinganzwa zvichitya, vanhu vakawanda vane CVID vanorarama hupenyu hwazvo hwese, hwakazara, nehutano hwakanaka nekuchengetwa kwakakodzera kwechiremba nekurapa.

Chii Chinonzi Kukanganiswa Kwema antibodies Enyika?

CVID inoitika kana masimba emuviri ako asingakwanisi kugadzira immunoglobulins zvakakwana, izvo zviri mapuroteni ane ma antibodies ako anorwisa hutachiona. Muviri wako unoita marudzi akasiyana-siyana emapuroteni aya, asi muCVID, mazinga acho anenge ari pasi pane zvakajairwa.

Shoko rokuti "variable" muzita rinoratidza kuti chirwere ichi chinotapura munhu mumwe nemumwe zvakasiyana. Vamwe vanhu vanorwara kazhinji, nepo vamwe vangave nematambudziko emuviri kana matambudziko ekugaya. Kukomba nezviratidzo zvinogona kusiyana zvikuru kubva kumunhu kuenda kumunhu, kunyange mumhuri imwe chete.

Vanhu vakawanda vane CVID vanoziviswa pavanenge vane makore makumi maviri kana makumi matatu, kunyange zvazvo zvingawanikwa muhudiki kana gare gare muhupenyu. Chirwere ichi chiri chenguva refu, zvinoreva kuti chiripo hupenyu hwese, asi chinogona kudzorwa zvikuru nekutsigirwa kwakakodzera kwechiremba.

Ndeapi Zviratidzo zveKukanganiswa Kwema antibodies Enyika?

Chiratidzo chakajairika chaungacherechedza ndechekurwara kazhinji kupfuura zvakajairwa, kunyanya nehutachiona hwekufema. Aya haasi marariyawo chete - anowanzova akakomba, anogara kwenguva refu, uye anodzokera kazhinji.

Aya ndiwo zviratidzo zvikuru zvinotaurwa nevanhu vane CVID:

• Hutachiona hwepakati pehuro hunoramba huchidzoka
• Pneumonia kana bronchitis inodzokazve kazhinji
• Hutachiona hwenzeve hunogara kwenguva refu
• Manyoka asingaperi kana matambudziko ekugaya
• Mashizha akafuta asingaperi
• Kuneta kusina kugadziriswa nekuzorora
• Hutachiona hwepande kana mabhuru

Vamwe vanhu vanorwarawo nezviratidzo zve autoimmune, umo masimba emuviri anorwisa zvinyama zvemukati zvakashata. Izvi zvingaratidza kurwadziwa kwemapfupa, matambudziko epanda, kana matambudziko eropa.

Muitiko usina kujairika, ungave nematambudziko akakomba senge chirwere chemapapu chisingaperi kana matambudziko eropa. Izvi zvinowanzoitika nekufamba kwenguva kana hutachiona husina kudzorwa zvakakwana, ndosaka kuongororwa nekurapa kwakakurumidza zvakakosha.

Chii Chinokonzera Kukanganiswa Kwema antibodies Enyika?

Chikonzero chaicho cheCVID hachizivisike zvizere, asi vatsvakurudzi vanoziva kuti chinosanganisira matambudziko ekukurukurirana kwemasero emuviri wako uye kushanda pamwe chete. Masero ako eB, ane basa rekugadzira ma antibodies, haashande zvakanaka kana kuti haakwanisi kukura kuva masero anogadzira immunoglobulins.

Genetics ine basa mune zviitiko zvakawanda. Vanenge 10-20% vevanhu vane CVID vane nhengo yemhuri ine chirwere ichi kana kushomeka kwemasimba emuviri. Zvisinei, zviitiko zvakawanda zvinoita sekunoitika pasina nhoroondo yakajeka yemhuri.

Masayendisiti akawana majeni akati wandei anogona kuita kuti pave neCVID kana akachinja kana kuti akachinjwa. Aya majeni anowanzo kubatsira kudzora basa remasimba emuviri, asi kana asingashandi zvakanaka, kugadzirwa kwema antibodies kunotambura.

Zvinhu zvakatipoteredza zvingaitawo kuti pave neCVID kune vanhu vane njodzi yekuzvarwa. Vamwe vatsvakurudzi vanofunga kuti hutachiona hwemavhairasi kana zvimwe zvinhu zvakatipoteredza zvingaita kuti chirwere ichi chibude, kunyange zvazvo izvi zvisina kubvumikiswa.

Rini Unofanira Kuona Chiremba Nekuda kweKukanganiswa Kwema antibodies Enyika?

Unofanira kufunga nezvekuona chiremba kana uri kurwara kazhinji, kunyanya nehutachiona hwekufema hunoramba huchigara kwenguva refu. Cherechedza kana uine hutachiona hupfuura mana kusvika ku6 pagore zvinoda mishonga.

Zvimwe zviratidzo zvinokurudzira zvinosanganisira hutachiona husina kugadziriswa nemishonga yakajairwa kana kuti hunoramba huchidzoka munzvimbo imwe chete. Semuenzaniso, kana wambova ne pneumonia kakawanda kana hutachiona hwepakati pehuro hunogara kwenguva refu husina kugadziriswa zvizere.

Usamirira kana uri kunetseka nematambudziko ekugaya pamwe nehutachiona hwenguva refu. Manyoka asingaperi, kurasikirwa nehuremu kusina kujekeswa, kana matambudziko emuviri anogara kwenguva refu pamwe nehutachiona hunodzokazve kazhinji zvinoda kuongororwa nachiremba.

Kana uine nhoroondo yemhuri yekushomeka kwemasimba emuviri uye uri kuona izvi, zvakakosha kutaura nachiremba wako. Kuongororwa kwakakurumidza kunogona kudzivirira matambudziko uye kuvandudza hupenyu hwako zvikuru.

Ndeapi Njodzi dzeKukanganiswa Kwema antibodies Enyika?

Kunzwisisa njodzi dzako kunogona kukubatsira iwe nemuongorori wako kuziva CVID pakutanga. Nhoroondo yemhuri ndiyo njodzi huru, sezvo chirwere ichi chinogona kuitika mumhuri kunyange kana chikonzero chaicho chemajini chisingazivikanwe.

Aya ndiwo njodzi huru dzaunofanira kuziva nezvadzo:

• Kuve nehama yepedyo ine CVID kana kushomeka kwemasimba emuviri
• Kuongororwa ne autoimmune conditions senge rheumatoid arthritis kana inflammatory bowel disease
• Kuve nemagene akachinja anokanganisa basa remasimba emuviri
• Kuve wechiEurope (kunyange zvazvo CVID inotapura vanhu vemarudzi ose)
• Zera - kunyange zvazvo zvingaitika pazera ripi zvaro, kuongororwa kwakawanda kunoitika pakati pemakore makumi maviri nemakumi mana

Zvakakosha kuyeuka kuti kuve nenjodzi hazvirevi kuti uchava neCVID. Vanhu vakawanda vane njodzi idzi havazombovi nechirwere ichi, nepo vamwe vasina njodzi yakajeka vanochiwana.

Bonde harisi njodzi huru, sezvo CVID inotapura varume nevakadzi zvakafanana. Chirwere ichi hachifambisi, saka haugoni kuchiwana kubva kune mumwe munhu.

Ndeapi Matambudziko Anogona Kuitika muKukanganiswa Kwema antibodies Enyika?

Kunyangwe CVID ichidzorwa, kunzwisisa matambudziko anogona kuitika kunokubatsira kuziva zvaunofanira kutarisa uye nei kurapa kwakakosha. Matambudziko mazhinji anoitika kana hutachiona husina kudzorwa zvakakwana nekufamba kwenguva.

Matambudziko akajairika anosanganisira:

• Kukuvadzwa kwemapapu kwenguva refu kubva kuhutachiona hwekufema hwakawanda
• Kukuvadzwa kwepakati pehuro kwenguva refu kunotungamira kumatambudziko anogara kwenguva refu
• Matambudziko ekugaya anosanganisira inflammatory bowel disease
• Autoimmune disorders inokanganisa nhengo dzakasiyana-siyana
• Spleen kana ropa rakakura
• Njodzi yakawedzera yekenza, kunyanya lymphoma

Matambudziko asingawanzoitika asi akakomba anogona kusanganisira bronchiectasis, iyo inokanganisa kufema. Vamwe vanhu vanorwara ne granulomas, izvo zviri zvidimbu zvidiki zvinopisa zvinogona kuumbwa munhengo dzakasiyana-siyana.

Mashoko akanaka ndeakuti nekurapa kwakakodzera uye kuongororwa, vanhu vakawanda vane CVID vanogona kudzivirira kana kuderedza matambudziko aya. Kuchengetwa kwechiremba nguva dzose uye kudzivirira hutachiona ndizvo zvinokosha pakurarama utano hwakanaka.

Kukanganiswa Kwema antibodies Enyika Kunooongororwa Sei?

Kuongorora CVID kunotanga nachiremba wako achiongorora nhoroondo yako yekurapa uye hutachiona hwaune. Vachatsvaga kuziva nezvehuwandu, kukomba, uye marudzi ehutachiona hwaune.

Kuongororwa kukuru kunoyera mazinga ako e immunoglobulin kuburikidza nekuongororwa kweropa nyore. Chiremba wako achaongorora mazinga eIgG, IgA, uye IgM - marudzi makuru ema antibodies anoitwa nemuviri wako. MuCVID, mazinga aya ari pasi pane zvakajairwa.

Chiremba wako anogonawo kuyedza kuti masimba ako emuviri anopindura sei kumajekiseni. Vachakupa majekiseni akati wandei uye vobva vaongorora kana muviri wako uchigadzira ma antibodies semhinduro. Kupindura kwakaipa kana kusavapo kwema antibodies kunobatsira kubvumikisa kuongororwa.

Kuongororwa kwakawedzerwa kunogona kusanganisira kuongorora nhamba yemasero ako eB neT uye kushanda. Aya kuongororwa kunobatsira chiremba wako kunzwisisa kuti masimba ako emuviri akakanganiswa sei uye kubvisa zvimwe zvirwere.

Kuongororwa kwemajini kunowanzo kurudzirwa, kunyanya kana uine nhengo dzemhuri dzine kushomeka kwemasimba emuviri. Kunyange zvazvo zvisingadiwe pakuongororwa, zvinogona kupa ruzivo rwakakosha pakuronga mhuri uye sarudzo dzekurapa.

Kurapa kweKukanganiswa Kwema antibodies Enyika Ndeapi?

Kurapa kukuru kweCVID ndekushandisa immunoglobulin replacement therapy, iyo inopa muviri wako ma antibodies asingakwanisi kuita pachawo. Kurapa uku kunoshanda zvikuru uye kunogona kuderedza hutachiona zvikuru.

Immunoglobulin therapy inogona kupiwa nenzira mbiri. Intravenous immunoglobulin (IVIG) inopihwa kuburikidza neIV mazuva ese 3-4, kazhinji muchipatara. Subcutaneous immunoglobulin (SCIG) inopfurwa pasi peganda vhiki nevhiki kana mazuva maviri evhiki uye inogona kuitwa kumba.

Chiremba wako acashanda newe kuti uwane huwandu hwakanaka uye nguva yakakodzera. Vanhu vakawanda vanotanga kunzwa zvakanaka mukati memwedzi mishoma yekutanga kurapa, nehutachiona hushoma uye simba rakawanda.

Mishonga inorwisa mabhakitiriya ine basa rinokosha pakudzorera CVID. Chiremba wako anogona kuinyora pakutanga kwehutachiona kana kuti kunyangwe kudzivirira kana uri munhu anorwara nehutachiona hwakati. Vamwe vanhu vanobatsirwa nemishonga inorwisa mabhakitiriya inogara kwenguva refu.

Kurapa kwakawedzerwa kunogona kusanganisira mishonga yekudzorera zviratidzo zve autoimmune kana zvikaitika. Chiremba wako achakutevera nguva dzose uye achichinja kurapa sezvinodiwa kuti urambe uine hutano hwakanaka.

Nzira Yekudzorera Kukanganiswa Kwema antibodies Enyika Kumba?

Kurarama zvakanaka neCVID kunosanganisira kutora matanho ekudzivirira hutachiona uye kuchengetedza hutano hwako hwese. Mazano akanaka ekutsvaira anoita kuti zvive zvakakosha zvikuru kana masimba emuviri ako achida rutsigiro rwakawanda.

Kutsvaira maoko ndiro danho rako rekutanga rekudzivirira. Geza maoko ako kazhinji neshampo nemvura kwemaminitsi makumi maviri, kunyanya usati wadya, mushure mekuenda kumberi, uye mushure mekuva munzvimbo dzevanhu.

Rambai muchiita majekiseni, asi shandirai pedyo nachiremba wenyu nezvekuti ndeapi akakodzera kwauri. Mazhinji emajekiseni asingapisi haana njodzi, asi majekiseni anorarama anowanzo dzivirirwa kune vanhu vane CVID.

Aya ndiwo mazano makuru ekudzorera kumba:

• Chengetera kudya kwakanaka kwakazara nemiriwo, miriwo, uye mapuroteni mashoma
• Zorora zvakakwana - edza maawa 7-9 usiku
• Ita zvemitambo nguva dzose, asi usashanda zvakanyanya
• Dzora kushushikana kuburikidza nemazano ekusagadzikana kana kurapa
• Dzivirira kuunganidzwa kwevanhu panguva yechando kana zvichibvira
• Usagovana zvinhu zvemunhu senge mabrush emazino kana makapu ekunwa

Cherechedza muviri wako uye usarega zviratidzo zvehutachiona pakutanga. Kana ukavamba kurapa hutachiona nekukurumidza, migumisiro yako ichave iri nani.

Ungagadzirira Sei Kune Chiremba Wako?

Kuagadzirira kuenda kuchiremba kunobatsira kuve nechokwadi chekuti unowana zvakawanda kubva panguva yako nemuongorori wako wehutano. Tanga nekugara uchinyora zviratidzo zvako, hutachiona, uye manzwiro ako zuva nezuva.

Nyora hutachiona hwose hwaune mugore rapfuura, kusanganisira nguva yavakaitika, kurapa kwawakagamuchira, uye nguva yakareba yavakagara. Ruzivo urwu runobatsira chiremba wako kuona zvinhu uye kuchinja kurapa kwako kana zvichidiwa.

Uya nehuremu hwemishonga yose uye zvinowedzerwa zvaunotora, kusanganisira huwandu uye nguva. Usakanganwa kusanganisira mishonga yepachena uye mavhitamini.

Gadzira mibvunzo yaunoda kubvunza chiremba wako. Mibvunzo yakajairika inogona kusanganisira kunetseka nezviratidzo zvitsva, mibvunzo nezvekuchinja kurapa, kana mazano ehupenyu. Kuanyora kunovimbisa kuti hausi kukanganwa nyaya dzakakosha.

Kana uri kuona chiremba mutsva, uya nemakopi ekuongororwa kwakaitwa, rekodhi dzemajekiseni, uye pfupiso yenhoroondo yako yekurapa. Izvi zvinovabatsira kunzwisisa nyaya yako nekukurumidza uye kupa kurapa kwakanaka.

Chii Chinonyanya Kukosha NezveKukanganiswa Kwema antibodies Enyika?

CVID chirwere chinodzorwa chisingafanire kudzora hupenyu hwako. Nekurapa kwakakodzera, vanhu vakawanda vane CVID vanogona kurarama hupenyu hwakanaka, hwazara nehutachiona hushoma uye matambudziko.

Chinhu chakakosha chokuyeuka ndechekuti kuongororwa kwakakurumidza nekurapa kwenguva dzose kunoita musiyano wese. Immunoglobulin replacement therapy inoshanda zvikuru, uye vanhu vakawanda vanoshamiswa nekuti vanonzwa zvakanaka sei pavatanga kurapa.

Kushanda pedyo neimmunologist kana mumwe nyanzvi ane ruzivo mukurapa CVID zvakakosha. Vanogona kukubatsira kufamba nesarudzo dzekurapa, kudzivirira matambudziko, uye kugadzirisa zvinetso zvinomuka.

Yeuka kuti kuve neCVID hazvirevi kuti uri munhu anorema kana kuti une miganho. Vanhu vakawanda vane chirwere ichi vanoita mabasa avo, kufamba, kurovedza muviri, uye kunakidzwa nezvinhu zvavanoda. Chinhu chikuru ndechekugara uine ruzivo, kutevera chirongwa chako chekurapa, uye kuchengetedza kutaurirana kwakanaka nechikwata chako chehutano.

Mibvunzo Inowanzo Bvunzwa NezveKukanganiswa Kwema antibodies Enyika

Unogona kurarama hupenyu hwakanaka neCVID here?

Hungu, vanhu vakawanda vane CVID vanorarama hupenyu hwazvo hwese, hwakazara, nehutano hwakanaka nekurapa kwakakodzera. Immunoglobulin replacement therapy inogona kuderedza hutachiona zvikuru, ichikubvumira kushanda, kufamba, kurovedza muviri, uye kuita zvinhu zvakawanda zvaunofarira. Chinhu chikuru ndechekurapa kwenguva dzose uye kushanda pedyo nechikwata chako chehutano.

CVID inogona kuwira mumhuri here?

CVID inogona kuitika mumhuri, asi zviitiko zvakawanda zvinoitika pasina nhoroondo yakajeka yemhuri. Vanenge 10-20% vevanhu vane CVID vane hama ine chirwere ichi kana kushomeka kwemasimba emuviri. Kunyange paine chikamu chemajini, chirwere ichi hachiteveri maitiro akareruka ekufambisa, saka kuve nehama ine CVID hazvirevi kuti iwe uchachiwana.

Kazhinji mangani unoda kurapwa kwe immunoglobulin?

Nguva yekurapa inotsamira pane rudzi rwe immunoglobulin therapy yaunowana. IVIG inowanzo pihwa mazuva ese 3-4 kuburikidza neIV, nepo SCIG inopihwa vhiki nevhiki kana mazuva maviri evhiki kuburikidza nekuipfurwa pasi peganda. Chiremba wako acasarudza nguva yakakodzera zvichienderana nema antibodies ako uye kuti unopindura sei kurapa.

CVID inogona kuipa nekufamba kwenguva here?

CVID pachayo inowanzosimba, asi matambudziko anogona kuitika kana hutachiona husina kudzorwa zvakakwana nekufamba kwenguva. Ndosaka kurapa kwenguva dzose nekuongororwa nguva dzose zvakakosha. Nekuchengetwa kwakakodzera, vanhu vakawanda vanoramba vaine hutano hwakanaka uye vanogona kunyange kuona kuvandudzika muzviratidzo zvavo uye hupenyu hwavo.

Kune zvokudya kana zvinhu zvandofanira kudzivisa neCVID here?

Haufaniri kutevera kudya kwakasarudzika, asi kuchengetedza kudya kwakanaka kunotsigira hutano hwako hwese. Dzivisa zvokudya zvisina kubikwa zvakanaka zvinogona kuva nema bacteria anokuvadza, uye chenjera nezvinhu zvemukaka zvisina kupasitirizwa. Zvinhu zvakawanda zvakajairwa zvakanaka, asi ungada kudzivisa kuunganidzwa kwevanhu panguva yechando uye nguva dzose ita zano rakanaka rekutsvaira.