Cushing Syndrome Chii? Zviratidzo, Zvinokonzera, & Kurapa

Cushing syndrome inoitika kana muviri wako uine homoni inonzi cortisol yakawanda kwenguva yakareba. Funga nezve cortisol sehomoni yemuviri wako inokubatsira kutarisana nemamiriro ezvinhu akaoma, asi kana mazinga ayo akakwira kwemwedzi kana makore, inogona kukanganisa chidimbu chega chega chemuviri wako.

Iyi mamiriro anobudirira zvishoma nezvishoma, zvinoreva kuti zviratidzo kazhinji zvinoonekwa zvishoma nezvishoma panguva. Vanhu vazhinji havazivi kuti pane chimwe chinhu chisina kunaka pakutanga nekuti shanduko dzinogona kuva diki. Mashoko akanaka ndeakuti nekurapa kwakakodzera uye kurapwa, vanhu vazhinji vane Cushing syndrome vanogona kuona kugadziriswa kukuru muzviratidzo zvavo uye hutano hwavo hwese.

Cushing Syndrome Chii?

Cushing syndrome chirwere chehomoni chinokonzerwa nekutarisa kwenguva yakareba kumahomoni e cortisol akawanda mumuviri wako. Mashizha ako e adrenal, ari pamusoro peitsvo dzako, kazhinji anoita cortisol kubatsira muviri wako kupindura kumanzwiro, kudzora shuga yeropa, uye kuderedza kuzvimba.

Kana mazinga e cortisol akaramba akakwira kwenguva yakareba, anokanganisa mabasa emuviri wako akajairika. Izvi zvinogona kuitika kana muviri wako uchiita cortisol yakawanda pachawo, kana kuti wakanga uchitora mishonga ye corticosteroid kwenguva yakareba.

Iyi mamiriro anoita vanhu vemazera ese, kunyange zvazvo kazhinji anoonekwa muvakuru vane makore 20 kusvika ku 50. Vakadzi vanenge katatu vanokwanisa kukura Cushing syndrome kupfuura varume, kunyanya kana zvakakonzerwa nematambudziko egland ye pituitary.

Zviratidzo zveCushing syndrome ndizvipi?

Zviratidzo zveCushing syndrome zvinogona kusiyana kubva kumunhu kuenda kumunhu, uye kazhinji zvinobudirira zvishoma nezvishoma zvekuti ungasazviziva pakarepo. Muviri wako uri kubata nematambudziko ekutarisa kwenguva yakareba kwehomoni yekumanikidzwa, izvo zvinoonekwa munzira dzakawanda.

Kushanduka kwemuviri kunonyanya kuonekwa kunosanganisira:

• Kuwedzera uremu, kunyanya kumativi ako epakati uye kumusoro kwemusana
• Chiso chakapoteredzwa, chakazara chinonziwo "moon face"
• Mashizha epepuru kana pink pane ganda rako
• Kutemwa nyore kubva pakukwenya diki kana kubata
• Kurapa kwakaoma kwemakomba, hutachiona, kana kutemwa
• Ganda rakapfava rinopwanya nyore
• Kushaya simba kwemhasuru, kunyanya mumaoko nemakumbo
• Kuderera kweropa
• Shuga yeropa yakakwira kana chirwere cheshuga

Kunze kwezviratidzo zvemuviri, Cushing syndrome kazhinji inokanganisa hutano hwako hwepfungwa uye hutano hwepfungwa. Ungave uine shanduko dzemanzwiro, kunzwa kusuruvara kana kunetseka, kuoma kuisa pfungwa, kana kushatirwa kunoratidzika kunge kwakasiyana newe.

Vamwe vanhu vanogadzira chimwe chinonzi "buffalo hump," icho chiri chikamu chemafuta pakati pemafudzi. Vakadzi vanogona kuona nguva dzisina kujairika dzemwedzi kana matambudziko ekubereka, nepo varume vangave vane kudzikira kwechido chepabonde kana erectile dysfunction.

Zvinokosha kucherechedza kuti kwete munhu wese ane izvi zviratidzo, uye vamwe vanhu vangave nezviratidzo zvishoma zviri nyore kukanganwa. Kana uri kuona shanduko dzakawanda idzi dzichiitika pamwe chete panguva, zvinokosha kutaura nachiremba wako.

Chii chinokonzera Cushing syndrome?

Cushing syndrome ine zvinokonzera zvakawanda, asi zvese zvinoguma muviri wako uine cortisol yakawanda. Kunzwisisa chikonzero chinokosha nekuti chinobatsira kuona nzira yakanakisa yekurapa mamiriro ako chaiwo.

Chikonzero chinonyanya kuitika ndechekutora mishonga ye corticosteroid kwenguva yakareba. Mishonga iyi, senge prednisone kana hydrocortisone, kazhinji inorayirwa kurapa mamiriro senge asthma, rheumatoid arthritis, kana inflammatory bowel disease. Kana yakatorwa muhuwandu hukuru kana kwenguva yakareba, inogona kutungamira kumatambudziko akafanana nekunge uine cortisol yakawanda yemukati.

Muviri wako unogona zvakare kuita cortisol yakawanda pachawo nekuda kwemamiriro ezvinhu akati wandei:

• Pituitary adenoma - ganda risina kenza rinowanikwa muganda rako repituitary rinogadzira ACTH yakawanda (homoni inoudza mashizha ako e adrenal kuti aite cortisol)
• Matumor e adrenal - kukura pamashizha ako e adrenal anogadzira cortisol yakawanda zvakananga
• Ectopic ACTH syndrome - kana matumor mune dzimwe nzvimbo dzemuviri wako achigadzira ACTH

Chikonzero chepituitary, dzimwe nguva chinonzi Cushing's disease, chinoita 80% yezviitiko apo muviri wako unoita cortisol yakawanda yemukati. Aya matumor epituitary anenge asingakonzere kenza, asi anoramba achiita matambudziko nekukanganisa kuenzana kwehomoni yako.

Zvishoma, matumor emuromo wako, pancreas, kana dzimwe nhengo dzinogona kuita ACTH, zvichikonzera kuwedzera kwe cortisol. Izvi zvinonzi ectopic ACTH syndrome uye zvinoda nzira dzakasiyana dzekurapa kupfuura zvinokonzerwa ne pituitary.

Rini unofanira kuona chiremba nekuda kweCushing syndrome?

Unofanira kufunga nezvekuona chiremba wako kana uri kuona zviratidzo zvakawanda zveCushing syndrome, kunyanya kana zviri kukanganisa hupenyu hwako hwezuva nezuva kana kuri kuwedzera panguva.

Rongedza musangano kana ukaona kuwedzera uremu kusina kujairika pamwe nezvimwe zviratidzo senge kutemwa nyore, kushaya simba kwemhasuru, kana shanduko dzemanzwiro. Aya mapoka ezviratidzo anoda kuongororwa nachiremba, kunyangwe chimwe nechimwe chacho chingaratidzika kunge chidiki.

Tsvaga kurapwa kwemishonga nekukurumidza kana ukawana zviratidzo zvakakomba senge kuderera kweropa kwakanyanya, shanduko dzemanzwiro kana kusuruvara kwakanyanya, zviratidzo zvechirwere cheshuga (kunyanyisa kunyorovesa, kuenda kunzvimbo kazhinji), kana uri kunetseka nemabasa ezuva nezuva nekuda kwekushaya simba kwemhasuru.

Kana uri kutora mishonga ye corticosteroid ikozvino uye uri kuona izvi zviratidzo, usarega mishonga yako kamwe kamwe, sezvo izvi zvingakuvadza. Pane kudaro, kurukurai zvinetso zvako nachiremba akakupa mishonga yacho kuitira kuti vagone kuongorora mamiriro ako uye kugadzirisa kurapwa kwako.

Zvinokonzera njodzi zveCushing syndrome ndizvipi?

Zvinhu zvakati wandei zvinogona kuwedzera mukana wako wekukura Cushing syndrome, kunyange zvazvo kuva nezvinokonzera njodzi hazvirevi kuti uchakura mamiriro acho. Kunzwisisa izvi zvinhu zvinogona kukubatsira iwe nemuongorori wako wehutano kuramba uchiri kuziva nezviratidzo zvinogona kuitika.

Chinokonzera njodzi huru ndiko kushandiswa kwenguva yakareba kwemishonga ye corticosteroid. Kana uri kutora mishonga iyi yekurapa mamiriro senge asthma, arthritis, kana autoimmune disorders, njodzi yako inowedzera nehuwandu hukuru uye nguva refu yekurapa. Zvisinei, mishonga iyi kazhinji inodiwa pakurapa mamiriro ezvinhu akakomba ehutano, saka mabhenefiti kazhinji anopfuura njodzi.

Zvinhu zvedemographics zvinokonzerawo basa:

• Kuva mudzimai, kunyanya pakati pemakore 20-50
• Kuva nemhuri yakakura yematambudziko ehormone
• Kuva nemamiriro ezvinhu akawanda emajini anokanganisa kugadzirwa kwehomoni

Kune Cushing syndrome inokonzerwa ne pituitary, hapana zvinokonzera njodzi zvakawanda zvinozivikanwa nekuti matumor epituitary kazhinji anobudirira pasina chikonzero chakajeka. Zvisinei, kuziva nezviratidzo kunova kukosha kana uine mamwe matambudziko ehormone kana nhoroondo yemhuri yemamiriro ehormone.

Zvinokosha kuyeuka kuti vanhu vazhinji vane izvi zvinokonzera njodzi havambofi vakakura Cushing syndrome. Izvi zvinhu zvinongoreva kuti ungabatsirwa nekuziva nezviratidzo zvinogona kuitika uye kukurukura chero zvinetso nachiremba wako.

Matambudziko anogona kuitika eCushing syndrome ndeapi?

Kana isina kurapwa, Cushing syndrome inogona kutungamira kumatambudziko akakomba ehutano nekuti mazinga e cortisol akawanda anokanganisa masisitimu akawanda emuviri. Mashoko akanaka ndeakuti akawanda ematambudziko aya anogona kugadziriswa zvakanyanya nekurapwa kwakakodzera, kunyanya kana akaonekwa pakutanga.

Matambudziko anonyanya kuitika anokanganisa hutano hwako hwemoyo nemwoyo:

• Kuderera kweropa kunogona kukanganisa moyo wako nemidziyero yeropa
• Chirwere cheshuga cheType 2 kubva kumazinga eshuga yeropa yakakwira
• Chirwere chemoyo uye kuwedzera njodzi yekurwara kwemoyo kana kurova
• Osteoporosis uye kuwedzera njodzi yekupwanya mapfupa
• Hutachiona hwakawanda nekuda kwekudzikira kwemagetsi
• Matombo etsvo kubva pakurasikirwa ne calcium

Matambudziko ehutano hwepfungwawo akakosha uye anogona kusanganisira kusuruvara kwakanyanya, kunetseka, uye mumamiriro ezvinhu mashoma, psychosis kana kufunga kuzviuraya. Aya maitiro epfungwa anogona kuva akaoma sezvinokonzerwa nemuviri uye kazhinji anogadziriswa nekurapwa.

Vamwe vanhu vanogadzira kushaya simba kwemhasuru, izvo zvinogona kuita kuti mabasa ezuva nezuva ave akaoma zvakanyanya. Vakadzi vanogona kuve nematambudziko ekubereka kana nguva dzisina kujairika, nepo varume vangave vane mazinga edzikira testosterone anokanganisa hutano hwavo hwese uye kunaka kwavo.

Chinhu chinokosha chekuyeuka ndechekuti kunyangwe aya matambudziko achiratidzika kutyisa, akawanda anodzoreredzwa kana kuti anogona kugadziriswa zvakanyanya nekurapwa kwakakodzera. Kuongororwa pakutanga uye manejimendi akakodzera anogona kudzivirira akawanda emamiriro ezvinhu akakomba.

Cushing syndrome inoongororwa sei?

Kuongorora Cushing syndrome kunoda matanho akawanda nekuti zviratidzo zvinogona kukonzerwa nemamiriro ezvinhu akasiyana, uye mazinga e cortisol anochinja zuva nezuva. Chiremba wako wehutano kazhinji anotanga nehurukuro yakakwana yezviratidzo zvako nenhoroondo yehutano.

Maitiro ekuongorora kazhinji anotanga nekuongororwa kweropa nemukaka kuyeresa mazinga ako e cortisol. Ungada kuunganidza mukaka wako kwemaawa 24 kana kutora mushonga unonzi dexamethasone kuona kuti muviri wako unopindura sei. Aya miedzo inobatsira kuona kana mazinga ako e cortisol ari kukwira zvechokwadi.

Kana miedzo yekutanga ichiratidza Cushing syndrome, chiremba wako achaodza miedzo yakawanda kuti awane chikonzero:

• MRI scans yeganda rako repituitary kutsvaga matumor
• CT scans yemasikirwo ako e adrenal
• Kuongororwa kweropa kuyeresa mazinga e ACTH
• Dzimwe nguva scans dzakawanda kutsvaga matumor mune dzimwe nzvimbo dzemuviri

Maitiro ekuongorora anogona kutora mavhiki kana mwedzi nekuti chiremba wako anoda kuva nechokwadi chekuongorora usati warayira kurapwa. Izvi zvinogona kunzwa zvine hasha, asi kuongororwa kwakakwana kunokosha pakusarudza nzira yakanakisa yekurapa.

Dzimwe nguva, vanachiremba vanogona kukurudzira kushanda ne endocrinologist, nyanzvi mune matambudziko ehormone, kubatsira nekuongorora uye kuronga kurapwa. Aya nyanzvi ane ruzivo rwakawanda mukutarisira mamiriro akakomba ehormone senge Cushing syndrome.

Kurapa kweCushing syndrome chii?

Kurapa kweCushing syndrome kunoenderana nezviri kukonzera mazinga ako e cortisol akakwira, asi chinangwa chaicho kugadzirisa cortisol kumazinga akajairika uye kutarisira chero matambudziko akaitika. Mashoko akanaka ndeakuti vanhu vazhinji vanoona kugadziriswa kukuru muzviratidzo zvavo nekurapwa kwakakodzera.

Kana Cushing syndrome yako yakakonzerwa nemishonga ye corticosteroid, chiremba wako acashanda newe kuderedza zvishoma nezvishoma dose kana kuchinja kune mamwe marapirwo. Iyi nzira inofanira kuitwa zvishoma nezvishoma uye nekuchenjerera kudzivirira zviratidzo zve withdrawal uye kuve nechokwadi chekuti mamiriro ako ari kutarisirwa.

Kune Cushing syndrome inokonzerwa nematumor, sarudzo dzekurapa dzinosanganisira:

• Kuopereta kubvisa matumor epituitary, matumor e adrenal, kana mamwe matumor anogadzira homoni
• Radiation therapy yematumor epituitary asingagone kubviswa zvachose nekuopereta
• Mishonga inodzivisa kugadzirwa kwe cortisol kana chiito
• Mune dzimwe nguva, kubviswa kwemasikirwo ese e adrenal kunoteverwa nekurapwa kwehomoni kwenguva yese

Kuopereta kazhinji ndiyo kurapwa kunonyanya kufarirwa kumatumor epituitary nekuti kunogona kurapa mamiriro acho kana tumo rose rakabviswa. Kuopereta kwakawanda kwe pituitary kunoitirwa kuburikidza nemuromo, zvinoreva kuti hapana kucheka kunze uye nguva yekudzorera inokurumidza.

Timu yako yehutano ichagamuchirawo kutarisira matambudziko senge kuderera kweropa, chirwere cheshuga, uye osteoporosis. Iyi nzira yakakwana inobatsira kuvandudza hutano hwako hwese uchitarisa kusawirirana kwehomoni.

Kudzoreredzwa kunotora nguva, uye ungasazvioni kugadziriswa pakarepo. Vanhu vazhinji vanotanga kunzwa zvakanaka mukati memwedzi mishoma yekurapwa kwakabudirira, kunyange zvazvo zvingatora gore kana kupfuura kuti zvimwe zviratidzo zvigadziriswe zvizere.

Nzira yekutarisira Cushing syndrome pamba?

Kunyangwe kurapwa kwemishonga kuchikosha kune Cushing syndrome, kune zvinhu zvakawanda zvaunogona kuita pamba kuti ubatsire kudzoreredzwa kwako uye utarise zviratidzo. Aya mazano anoshanda zvakanaka kana akabatana nekurapwa kwako kwemishonga, kwete sechinoshandiswa chacho.

Tarisisa kudya kudya kwakaringana kunobatsira kutarisira shuga yeropa uye kutsigira hutano hwemfupa. Izvi zvinoreva kusarudza zviyo zvizere, mapuroteni akapfava, michero, uye miriwo uchideredza zvokudya zvakagadzirwa, shuga yakawanda, uye sodium. Sezvo Cushing syndrome inogona kukanganisa shuga yeropa, kushanda nenutritionist kunogona kubatsira zvikuru.

Kuita zvemitambo zvinogona kubatsira nezviratidzo zvakawanda, asi tanga zvishoma sezvo kushaya simba kwemhasuru kuri kazhinji. Kufamba, kushambira, kana kurovedza muviri kwakasimba kunogona kubatsira kuchengetedza mhasuru uye kuwanda kwemfupa. Gara uchibvunza chiremba wako usati watanga kurovedza muviri matsva.

Kutarisira hutano hwako hwepfungwa kwakakoshawo:

• Funga nezvekurapa kana kurapa kubatsira kubata neshumo dzemanzwiro nekunetseka
• Ita nzira dzekuderedza kunetseka senge kufema kwakadzika kana kufungisisa
• Chengetedza hukama hwenharaunda uye usazviparadzanisa
• Wana hope dzakakwana, kunyange zvazvo izvi zvingave zvakaoma neCushing syndrome

Tarisa ganda rako zvakanyanya sezvo ringave rakapfava kupfuura zvakajairwa. Shandisa zvigadzirwa zve ganda zvinyoro, dzivisa kusimbiswa kwezuva, uye chenjera kudzivirira kukuvara kunogona kutungamira mumakomba anorapa zvishoma.

Chengetedza zviratidzo zvako uye chero shanduko dzaunoona. Iyi ruzivo inogona kukosha kune chiremba wako pakugadzirisa chirongwa chako chekurapa uye kutarisira kufambira mberi kwako.

Unofanira kugadzirira sei musangano wako nachiremba?

Kugadzirira musangano wako kunogona kubatsira kuve nechokwadi chekuti unowana zvakanyanya kubva panguva yako nemuongorori wako wehutano. Sezvo zviratidzo zveCushing syndrome zvingasiyana uye zvichibudirira zvishoma nezvishoma, kugadzirira kwakanaka kunova kukosha zvikuru.

Usati wasangana, nyora pasi zviratidzo zvako zvese, kunyange izvo zvingaratidzika kunge hazvina hukama. Sanganisira paunotanga kuona chimwe nechimwe chezviratidzo uye kana zvakawedzera panguva. Tora mifananidzo kana ukaona shanduko mukuonekwa kwako, sezvo izvi zvingabatsira chiremba wako kuona.

Gadzira runyorwa rwakakwana remishonga yese yaunotora, kusanganisira mishonga inorayirwa, mishonga inotengeswa pasina kuraira, uye zvinowedzerwa. Tarisa zvikuru chero mishonga ye corticosteroid yaunotora, kusanganisira paunotanga uye huwandu hwaunotora.

Uya neruzivo rwenhoroondo yako yehutano uye chero nhoroondo yemhuri yematambudziko ehormone kana matambudziko ehormone. Kana uine miedzo yeropa yapfuura kana mifananidzo yemishonga, uya nemigumisiro iyoyo kana zvichibvira.

Nyora mibvunzo yaunoda kubvunza chiremba wako:

• Ndeapi miedzo yandinoda kusimbisa kuongororwa?
• Chii chingave chiri kukonzera zviratidzo zvangu?
• Ndeapi marapirwo angu?
• Zvingatora nguva yakareba sei kuona kugadziriswa?
• Ndeapi matambudziko andinofanira kutarisa?

Funga nezvekutora shamwari yakavimbika kana nhengo yemhuri kumusangano wako. Vanogona kukubatsira kuyeuka ruzivo rwakakosha uye kupa rutsigiro rwepfungwa panguva inogona kuva yakaoma.

Chii chinonyanya kukosha nezve Cushing syndrome?

Cushing syndrome chirwere chinogona kutarisirwa chinoitika kana muviri wako uine cortisol yakawanda kwenguva yakareba. Kunyangwe zvingakonzera zviratidzo zvakakomba nematambudziko, chinhu chinokosha chekuyeuka ndechekuti vanhu vazhinji vanoona kugadziriswa kukuru nekurapa kwakakodzera uye kurapwa.

Kiyi yekubudirira kwakabudirira ndiko kuziva pakutanga nekurapa. Kana uri kuona zviratidzo zvakawanda zvingaratidza Cushing syndrome, kunyanya kana zviri kukanganisa hupenyu hwako, usambofunga kutaura nazvo nachiremba wako wehutano.

Kubudirira kwakabudirira kazhinji kunoenderana nechinokonzera, asi kunyangwe mumamiriro ezvinhu akakomba, kune akawanda marapirwo anowanikwa. Vanhu vazhinji vanogona kutarisira kuona kugadziriswa kwakawanda muzviratidzo zvavo pamwedzi kusvika kumakore anotevera kurapwa kwakabudirira.

Yeuka kuti kudzoreredzwa inzira, kwete shanduko yeusiku. Iva nemoyo murefu newe sezvo muviri wako uchigadzirisa kumazinga e cortisol akajairika, uye chengetedza kutaurirana kwakashama netimu yako yehutano mukati me rwendo rwako rwekurapa.

Mibvunzo inobvunzwa kazhinji nezve Cushing syndrome

Cushing syndrome inogona kupera pachayo here?

Cushing syndrome kazhinji haipere pasina kurapwa. Kana yakakonzerwa nemishonga, zviratidzo zvinogona kugadziriswa kana mushonga wakaderedzwa zvakakodzera kana wakamiswa pasi pekutarisirwa kwemishonga. Zvisinei, kana yakakonzerwa nematumor kana mamwe mamiriro ezvinhu, kurapwa kwakakosha kazhinji kunoitika kugadzirisa mazinga e cortisol uye kudzivirira matambudziko.

Zvinotora nguva yakareba sei kudzoreredzwa kubva kuCushing syndrome?

Nguva yekudzoreredzwa inosiyana zvichienderana nechinokonzera uye nzira yekurapa. Vamwe vanhu vanotanga kunzwa zvakanaka mukati memwedzi mishoma yekurapwa kwakabudirira, nepo vamwe vangatora gore kana kupfuura kuona kugadziriswa kwakazara. Kushanduka kwemuviri senge kugoverwa kweuremu nesimba remhasuru kazhinji kunotora nguva yakareba kugadzirisa kupfuura zviratidzo senge shanduko dzemanzwiro kana matambudziko ekurara.

Cushing syndrome yakafanana here neCushing's disease?

Cushing's disease chaizvoizvo rudzi rwakakosha rweCushing syndrome. Cushing syndrome izwi rakajairika rekunge uine cortisol yakawanda, pasinei nechinokonzera. Cushing's disease inoreva zviitiko zvakakonzerwa ne tumor ye pituitary inogadzira ACTH yakawanda, iyo inoita kuti mashizha e adrenal agadzire cortisol yakawanda.

Kumanikidzwa kunogona kukonzera Cushing syndrome here?

Kunyangwe kumanikidzwa kwenguva refu kunogona kuwedzera mazinga e cortisol kwenguva pfupi, kazhinji hakuiti Cushing syndrome. Zvisinei, zviratidzo zvekunetseka kwenguva refu dzimwe nguva zvinogona kufanana nezviratidzo zveCushing syndrome, ndosaka kuongororwa kwemishonga kwakakosha. Cushing syndrome chaiyo inokonzerwa nemamiriro ezvinhu emishonga kana mishonga, kwete nekumanikidzwa kwepfungwa chete.

Ndichada kutora mishonga kwenguva yese here mushure mekurapwa?

Izvi zvinoenderana nekurapwa kwako kwakakosha uye kuti muviri wako unopindura sei. Kana uine kuopereta kubvisa tumor ye pituitary uye yakabudirira zvizere, ungasada mishonga ye nguva refu. Zvisinei, kana mashizha ese e adrenal akabviswa, uchada kurapwa kwehomoni kwenguva yese. Chiremba wako wehutano acashanda newe kuti aone chirongwa chakanakisa chekutarisira kwenguva refu mamiriro ako.