Huntington's Disease Chii? Zviratidzo, Zvinokonzera, & Kurapa

Huntington's Disease Chii?

Huntington's disease chirwere chepfungwa chinokonzerwa negene rakaora rinoparadza masero epfungwa munzvimbo dzakasiyana-siyana dzeuropi. Izvi zvinoita kuti munhu ave nematambudziko ekufamba, kufunga, uye manzwiro. Chirwere ichi chinogara chichiwedzera zvishoma nezvishoma.

Fungidzira uropi seguta rine nzvimbo dzakasiyana-siyana. Huntington's disease inoparadza nzvimbo dzinoona nezve kufamba uye kugona kwepfungwa. Chirwere ichi chinotanga zvishoma nezvishoma, zvichireva kuti zviratidzo zvinoonekwa zvishoma nezvishoma kwete kamwe kamwe.

Chirwere ichi hachisi chinowanzoitika, chinoonekwa kune vanhu 3 kusvika ku7 pane vanhu 100,000 pasi rose. Kunyange zvazvo iri chirwere chakakomba, kunzwisisa chirwere ichi kunogona kukubatsira iwe nemhuri yako kuronga ramangwana renyu uye kuwana rubatsiro rwaunoda.

Zviratidzo zveHuntington's Disease Ndezvipi?

Zviratidzo zveHuntington's disease kazhinji zvinoonekwa pakati pemakore 30 ne50, kunyange zvazvo zvingatanga kare kana gare gare. Chirwere ichi chinotambudza zvikamu zvitatu zvikuru zvehupenyu hwako, uye zviratidzo kazhinji zvinoenderana uye zvinochinja nguva nenguva.

Zviratidzo zvekutambudzika kufamba ndizvo zvinoonekwa pakutanga:

• Kufamba kwemuviri kusina kuzivikanwa (kunonzi chorea)
• Matambudziko emuviri senge kuoma kana kuoma kwemhasuru
• Kufamba kwemasikiro kwemasikiro
• Kunetseka kufamba, kumira, uye kuenzanisa
• Kunetseka kutaura kana kunwa
• Kunetseka nemabasa anoda hunyanzvi hwemasimba madiki senge kunyora

Zviratidzo zvepfungwa zvinotambudza kufunga kwako uye zvinogona kunge zvakaoma sezvinetso zvekutambudzika kufamba:

• Kunetseka kuronga, kupa zvinhu zvakakosha, kana kuisa pfungwa pane mabasa
• Matambudziko ekushandura mafungiro
• Kunetseka kudzora mafungiro
• Kuita zvinhu zvishoma nezvishoma kana kuwana mazwi
• Matambudziko ekurangarira, kunyanya kudzidza ruzivo rutsva

Zviratidzo zvemanzwiro uye zvepfungwa kazhinji zvinoonekwa pamwe chete nekuchinja kwemuviri:

• Kuora mwoyo uye kushanduka-shanduka kwemanzwiro
• Kushatirwa uye kutsamwa
• Kunetseka uye kusava neshamwari
• Maitiro ekumanikidzwa
• Psychosis mumamiriro ezvinhu asingawanzoitika

Aya maratidzo haaonekwi panguva imwe chete, uye ruzivo rweumwe neumwe rwusiyana. Vamwe vanhu vangacherechedza kuchinja kwekutambudzika kufamba kutanga, nepo vamwe vachigona kuona kuchinja kwemanzwiro kana kufunga usati waona chero zviratidzo zvemuviri.

Chii Chinokonzera Huntington's Disease?

Huntington's disease inokonzerwa nekuchinja kwegene rimwe chete rinonzi huntingtin gene (HTT). Gene iri rinowanzo kubatsira masero epfungwa kushanda zvakanaka, asi kana rakaora, rinogadzira protein inokuvadza masero epfungwa zvishoma nezvishoma.

Chirwere ichi chinotevera chimiro chekuwira chinonzi "autosomal dominant." Izvi zvinoreva kuti unongoda kuwana kopi imwe chete yegene rakaora kubva kumubereki mumwe chete kuti ubate chirwere ichi. Kana mumwe wemubereki vako akawana Huntington's disease, une mukana we50% wekuchiwana.

Kusiyana nezvimwe zvirwere zvakawanda, hapana zvinhu zvakatipoteredza kana maitiro ehupenyu anokonzera Huntington's disease. Igene chete, zvinoreva kuti haisi chinhu chawakanga usina kudzivirira kana chawakakonzeresa nemaitiro ako.

Mumamiriro ezvinhu asingawanzoitika, kuchinja kwegene kunogona kuitika pasina kuwanikwa kubva kumubereki. Izvi zvinoitika mune zvishoma pane 10% yezviitiko uye zvinowanzoitika kana chirwere ichi chatanga pazera duku kwazvo.

Rini Unofanira Kuona Chiremba Nezve Huntington's Disease?

Unofanira kuona chiremba kana ukaona matambudziko ekufamba anogara kwenguva yakareba, kunyanya kufamba kwemuviri kusina kuzivikanwa kunokanganisa mabasa ezuva nezuva. Zviratidzo zvepakutanga zvinogona kusanganisira kusakwanisa kufamba zvakanaka, kunetseka kuenzanisa, kana kufamba kwemuviri kusina kujairika kunoratidzika kuuya nekufamba.

Kuchinja mufunge kana manzwiro ako kunogara kwemavhiki kana mwedzi kunodawo kutarisirwa nachiremba. Izvi zvinosanganisira kunetseka kuisa pfungwa, kuita sarudzo, kana kuchinja kwepfungwa kunoratidzwa nemhuri yako.

Kana uine nhoroondo yemhuri yeHuntington's disease, zvakakosha kutaura nezvekurairwa kwegene nachiremba wako, kunyangwe usati wava nezviratidzo. Kukurukura uku kunogona kukubatsira kunzwisisa njodzi dzako uye kuita sarudzo dzakachenjera pamusoro pekuongororwa kwegene.

Usamirira kuti zviratidzo zvive zvakakomba usati watanga kutsvaga rubatsiro. Kuongororwa pakutanga kunokubvumira kuwana kurapwa kunogona kubatsira kudzora zviratidzo uye kubatana nemabasa ekutsigira anogona kuvandudza hupenyu hwako.

Zvinhu Zvinowedzera Njodzi yeHuntington's Disease Ndezvipi?

Chinhu chikuru chinowedzera njodzi yeHuntington's disease ndechekuva nemubereki ane chirwere ichi. Sezvo iri chirwere chegene chinonzi autosomal dominant, mwana wese wemubereki ane chirwere ichi ane mukana we50% wekuwana gene rakaora.

Zera rinogona kukanganisa nguva iyo zviratidzo zvinoonekwa, kunyange zvazvo risina kukanganisa kana uchave uine chirwere ichi. Vanhu vakawanda vane Huntington's disease vanotanga kuratidza zviratidzo pakati pemakore 30 ne50, asi chirwere ichi chinogona kutanga kare kana gare gare muhupenyu.

Mumamiriro ezvinhu asingawanzoitika, Huntington's disease yevechidiki inogona kutanga usati wasvika makore 20. Iyi fomu inotanga nekukurumidza inowanzova yakakomba uye inokurumidza kupfuura fomu yevanhu vakuru. Inowanzoitika kana gene rakaora rawanikwa kubva kuna baba.

Kusiyana nezvimwe zvirwere zvakawanda, zvinhu zvehupenyu senge kudya, kurovedza muviri, kana zvinhu zvakatipoteredza hazviwedzeri kana kuderedza njodzi yekuwana Huntington's disease. Chirwere ichi chinotsanangurwa zvizere negene.

Matambudziko Anogona Kuitika muHuntington's Disease Ndezvipi?

Sezvo Huntington's disease ichikura, inogona kukonzera matambudziko akawanda anokanganisa zvikamu zvakasiyana-siyana zvehupenyu hwako uye hupenyu hwako hwezuva nezuva. Kunzwisisa aya mikana kunogona kukubatsira iwe nemhuri yako kugadzirira uye kutsvaga kutarisirwa kwakakodzera.

Matambudziko ekufamba kazhinji anowedzera nguva nenguva:

• Njodzi yakawedzera yekuwa nekuda kwekusakwanisa kuenzanisa uye kuwirirana
• Kunetseka kunwa, izvo zvinogona kukonzera kukwakuka kana aspiration pneumonia
• Matambudziko akakomba ekufamba anoita kuti kufamba kana kuzvichengeta zvive zvakaoma
• Kuomarara kwemhasuru kana kuoma kunoderedza kufamba

Matambudziko epfungwa nemafambisirwo anogona kukanganisa zvakanyanya kushanda kwezuva nezuva:

• Kuwedzera kunetseka kuita sarudzo uye kugadzirisa matambudziko
• Kuora mwoyo kwakakomba kunogona kusanganisira pfungwa dzekuzviuraya
• Maitiro ekutsamwa anogona kukanganisa ukama
• Kuenderera mberi zvachose pane vamwe vanhu kuti vatarisire zuva nezuva

Matambudziko ezvokurapa anogona kuitika sezvo chirwere ichi chikukura:

• Kurasikirwa nehuremu uye kushaya zvokudya nekuda kwekunetseka kudya
• Zvirwere zvekufema nekuda kwekunetseka kunwa
• Matambudziko emoyo mune dzimwe nguva
• Matambudziko kubva pakuwa kana kukuvara

Kunyangwe aya matambudziko achionekwa sekukomba, mazhinji anogona kutarisirwa nekutarisirwa kwakakodzera kwemishonga uye rutsigiro. Kushanda pedyo nechikwata chako chehutano kunogona kubatsira kudzivirira kana kuderedza akawanda eaya matambudziko.

Huntington's Disease Inozwivikanwa Sei?

Kuziva Huntington's disease kazhinji kunosanganisira kuongororwa kwemishonga, nhoroondo yemhuri, uye kuongororwa kwegene. Chiremba wako anotanga nekukurukura zviratidzo zvako uye chero nhoroondo yemhuri yechirwere ichi.

Kuongororwa kwepfungwa kunobatsira kuongorora kufamba kwako, kuwirirana, kuenzanisa, uye kushanda kwepfungwa. Chiremba wako anogona kukukumbira kuti uite mabasa ari nyore senge kufamba, kufambisa minwe yako, kana kupindura mibvunzo kuti aone kuti chirwere ichi chiri kukukanganisa sei.

Kudzidza kwemaitiro europi, senge CT kana MRI scans, kunogona kuratidza kuchinja kwakajairika mumaitiro europi kunoitika neHuntington's disease. Aya ma scan anobatsira kubvisa zvimwe zvirwere uye anogona kuratidza huwandu hwekuchinja kweuropi.

Kuongororwa kwegene kunopa kuongororwa kwakajeka. Kuongororwa kweropa kuri nyore kunogona kuona gene rakaora re huntingtin. Kana uine zviratidzo uye kuongororwa kwegene kwakanaka, kuongororwa kunosimbiswa. Kuongororwa uku kunogona kuitwawo usati wava nezviratidzo kana uine nhoroondo yemhuri yechirwere ichi.

Kuongororwa kwepfungwa uye zvepfungwa kunobatsira kuongorora kushanda kwepfungwa uye zviratidzo zvemanzwiro. Aya maonero anogona kuona kuchinja kwekutanga mufunge, kurangarira, uye manzwiro ausingagone kuona muhupenyu hwezuva nezuva.

Kurapa kweHuntington's Disease Ndeapi?

Kunyangwe pasina mushonga weHuntington's disease ikozvino, kurapwa kwakawanda kunogona kubatsira kudzora zviratidzo uye kuvandudza hupenyu. Chinangwa ndechekubatsira kuchengetedza basa uye kugadzikana kwenguva yakareba sezvinobvira.

Mishonga inogona kubatsira kudzora zviratidzo zvakasiyana-siyana:

• Tetrabenazine kana deutetrabenazine yekufamba kwemuviri kusina kuzivikanwa
• Mishonga inorwisa psychosis yekukomba chorea uye zviratidzo zvemafambisirwo
• Mishonga inorwisa kuora mwoyo yekuora mwoyo uye kunetseka
• Mishonga inogadzirisa manzwiro ekushatirwa uye kutsamwa

Kurapa kwemuviri kunobatsira kuchengetedza kufamba uye kuenzanisa uku kuchideredza njodzi yekuwa. Therapist yako inogona kukudzidzisa maekisesaizi ekuchengetedza simba remhasuru uye kunyanya, uye kukurudzira zvinhu zvinobatsira kana zvichidiwa.

Kurapa kutaura kunova kukosha sezvo chirwere ichi chikanganisa kugona kwako kutaura nekudya. Munyori wekutaura anogona kukubatsira kutaurirana zvakanyanya uye kudzidzisa nzira dzakachengeteka dzekudya kudzivirira kukwakuka.

Kurapa kwemashandiro kunotarisa pakukubatsira kugadzirisa mabasa ezuva nezuva uye kuchengetedza kuzvimiririra. Izvi zvinogona kusanganisira kuchinja nzvimbo yako yekugara kana kudzidza nzira itsva dzekuita mabasa sezvo unyanzvi hwako huchichinja.

Rutsigiro rwekudya rwakakosha sezvo kunetseka kunwa kuchikura. Dietitian anogona kukubatsira kuve nechokwadi chekuti uri kudya zvokudya zvakakwana uye anogona kukurudzira kuchinja kwezvokudya kana zvinowedzerwa sezvinodiwa.

Nzira Yekutarisira Huntington's Disease Pamba?

Kuita nzvimbo yekugara yakachengeteka uye inotsigira kunogona kuita musiyano mukuru mukutarisira Huntington's disease. Kuchinja kuri nyore kunogona kukubatsira kuchengetedza kuzvimiririra uye kuderedza njodzi yekukuvara.

Kuchinja kuchengetedza kumba kwako kunosanganisira kubvisa makarpeti asina kusimba, kuisa mahandrails pamaketani, uye kuve nechiedza chakanaka munzvimbo yako yekugara. Funga nezvekugadzirisa fenicha kuti uite nzira dzakajeka uye kuderedza njodzi yekuwa.

Kuita maitiro kunogona kubatsira nezviratidzo zvepfungwa uye kuderedza kusanzwisisika. Edza kuchengetedza nguva dzokudya dzakafanana, nguva yemishonga, uye mabasa ezuva nezuva. Kushandisa makarinda, zvinyorwa zvekuyeuchidza, uye pill organizers kunogona kubatsira nematambudziko ekurangarira.

Kudya kunoda kutarisirwa sezvo chirwere ichi chikukura. Tarisa pazvokudya zvine zvinovaka muviri uye funga kudya zvishoma, zvokudya zvakawanda kana kunwa kuchiva kuoma. Gara wakanyorova uye shanda nechikwata chako chehutano kana kudya kuchiva kuoma.

Kuramba uchiita zvemuviri mukati mekugona kwako kwakakosha kune hutano hwemuviri nepfungwa. Maekisesaizi ari nyore senge kufamba, kushambira, kana kunyanya kunogona kubatsira kuchengetedza simba remhasuru uye kunyanya uku uchigovera mabhenefiti emanzwiro.

Kusimudzira uye kuchengetedza hukama hwevanhu kunobatsira kurwisa kusurukirwa uye kuora mwoyo. Gara uchibatana nemhuri neshamwari, funga kubatana nemapoka ekutsigira, uye usatya kukumbira rubatsiro kana uchida.

Ungagadzirira Sei Kune Chiremba Wako?

Kugadzirira kushanya kwako kuchiremba kunogona kubatsira kuve nechokwadi chekuti unowana zvakanyanya kubva pakushanya kwako uye kugadzirisa zvinetso zvako zvese. Tanga nekutsanangura chero zviratidzo zvawakaona, kusanganisira nguva zvakatanga uye nzira zvavachinja nayo.

Uyisa runyorwa rwakakwana remishonga yako iripo, kusanganisira madhoshi uye chero zvinowedzerwa zvepamusoro-pe-kauntare. Zvakare, cherechedza chero migumisiro yaunogona kuva nayo kubva pakurapwa kuripo.

Ruzivo rwenhoroondo yemhuri rwakakosha kune Huntington's disease. Unganidza ruzivo nezvehama dzakanga dzine chirwere ichi, kusanganisira zviratidzo zvavo nemakore ekutanga. Ruzivo urwu runobatsira chiremba wako kunzwisisa mamiriro ako chaiwo zviri nani.

Funga kuuya nemumwe wemhuri kana shamwari pakushanya kwako. Vanogona kukubatsira kuyeuka mibvunzo yekubvunza, kunyora panguva yekushanya, uye kupa kucherechedzwa kuwedzerwa nezvekuchinja kwavakaona mauri.

Gadzira runyorwa rwemibvunzo usati watanga. Ungada kubvunza nezve nzira dzekurapa, kufambira mberi kunotarisirwa, zviwanikwa zvekupa rubatsiro, kana kuronga ramangwana. Usazvidya mwoyo nezvekubvunza mibvunzo yakawanda - chiremba wako anoda kukubatsira kunzwisisa mamiriro ako.

Chii Chinonyanya Kukosha Nezve Huntington's Disease?

Huntington's disease chirwere chegene chinokanganisa, asi kunzwisisa kunokupa simba rekuita sarudzo dzakachenjera pamusoro pekutarisirwa kwako neramangwana. Kunyangwe chirwere ichi chikukura, vanhu vakawanda vanorarama hupenyu hunogutsa kwemakore akawanda mushure mekuongororwa nerutsigiro rwakakodzera nekurapwa.

Kuongororwa nekurapwa pakutanga kunogona kuvandudza hupenyu hwako zvakanyanya uye kukubatsira kuchengetedza basa kwenguva yakareba. Chinhu chikuru ndechekushanda pedyo nechikwata chako chehutano kuti ugadzire chirongwa chekutarisira chakakwana chinogadzirisa zvaunoda uye zviratidzo zvako.

Yeuka kuti hausi wega munzira iyi. Mapoka ekutsigira, vanachiremba, uye masangano akatsaurirwa kuHuntington's disease anogona kupa zviwanikwa zvinokosha, ruzivo, uye rutsigiro rwemanzwiro kwauri nemhuri yako.

Kuronga usati watanga, kunyange zvakaoma, kunogona kubatsira kuve nechokwadi chekuti zvaunoda zvinoremekedzwa uye kuderedza kushushikana kune vadikani vako. Funga nezvekukurukura zvaunoda pamusoro pekutarisirwa kwenguva refu nemhuri yako nechikwata chehutano paunogona kuita izvi zvisarudzo zvakajeka.

Mibvunzo Inowanzo Bvunzwa Nezve Huntington's Disease

Q1: Huntington's disease inogona kudzivirirwa here?

Zvinosuruvarisa, Huntington's disease haigone kudzivirirwa sezvo inokonzerwa nekuchinja kwegene. Zvisinei, kurairwa kwegene kunogona kubatsira vanhu vane njodzi kunzwisisa mikana yavo yekuwana chirwere ichi uye kuita sarudzo dzakachenjera dzekuronga mhuri. Vamwe vanhu vanosarudza kuongororwa kwegene vasati vava nevana kuti vanzwisise njodzi dzekuendesa chirwere ichi kuvana vavo.

Q2: Vanhu vanorarama kwenguva yakareba sei neHuntington's disease?

Nguva yekurarama mushure mekutanga kwezviratidzo inowanzo makore 15 kusvika ku20, kunyange zvazvo izvi zvichienderana zvikuru nemunhu. Vamwe vanhu vanogona kurarama kwenguva yakareba, nepo vamwe vachigona kuona kufambira mberi kukurumidza. Fomu yevechidiki inowanzo kukurumidza kupfuura Huntington's disease yevanhu vakuru. Hupenyu hwakanaka uye kutarisirwa kwakakodzera kwemishonga zvine basa rinokosha muhutano hwakazara mukati mechirwere.

Q3: Kuongororwa kwegene kunokurudzirwa here kune vemhuri?

Kuongororwa kwegene chisarudzo chemunhu chinofanira kuitwa nekurairwa kwegene. Kuongororwa kunogona kuitwa usati wava nezviratidzo, asi zvakakosha kufunga nezvemigumisiro yepfungwa yekuziva kuti uchave uine chirwere ichi. Vamwe vanhu vanoda kuziva kuti vanogona kuronga hupenyu hwavo nenzira yakakodzera, nepo vamwe vachisarudza kusaita kuongororwa. Hapana sarudzo yakarurama kana yakaipa.

Q4: Kuchinja kwehupenyu kunogona kuderedza kufambira mberi kweHuntington's disease here?

Kunyangwe kuchinja kwehupenyu kuchigona kurega kana kuderedza zvakanyanya kufambira mberi kwechirwere, kuchengetedza hutano hwakanaka hwakazara kunogona kukubatsira kunzwa zvakanaka uye kushanda kwenguva yakareba. Kurovedza muviri nguva dzose, kudya kwakakodzera, kuramba uchiita zvepfungwa, uye kudzora kushushikana kunogona kubatsira nezviratidzo uye hutano hwakazara. Kurapa kwemuviri nekurapa kutaura kunogona zvakare kubatsira kuchengetedza basa kwenguva yakareba.

Q5: Rutsigiro rwei ruripo kune mhuri dzine Huntington's disease?

Zviwanikwa zvakawanda zviripo zvinosanganisira Huntington's Disease Society of America, mapoka ekutsigira enyika, vanorayira gene, uye mapoka ehutano akasarudzika. Aya masangano anopa dzidzo, rutsigiro rwemanzwiro, kutsigira, uye rubatsiro rwakakosha. Minda yakawanda inewo mabasa ekutarisira uye mamwe mapurogiramu ekutsigira kune mhuri dzakabatwa neHuntington's disease.