Invasive Lobular Carcinoma (ILC) iri: Zviratidzo, Zvinokonzera, Kurapa

Invasive lobular carcinoma (ILC), rudzi rwechipiri rwakajairika rekenza yemukaka, inoumba 10-15% yezvirwere zvekenza yemukaka. Kusiyana nemamwe marudzi ekenza yemukaka anoumba zvidumbu zvakajeka, ILC inokura mumapoka madiki-diki kuburikidza ne tishu yemukaka, izvi zvichiita kuti zviome kuziva pakuongororwa kwemuviri nemidziyo yekuongorora.

Rudzi urwu rwekenza runotanga mumagaro anogadzira mukaka (lobules) yemukaka wako wozoenda kune dzimwe tishu dzepedyo. Kunyangwe shoko rokuti "invasive" richinzwa richitya, rinoreva kuti masero ekenza aenda kure nekwakatanga. Vanhu vakawanda vane ILC vanopindura zvakanaka pakurapa, kunyanya kana yakawanikwa pakutanga.

Zviratidzo zve Invasive Lobular Carcinoma ndeapi?

ILC kazhinji haigadzire chidumbu chakaoma chinowanzozivikanwa nevanhu sekenza yemukaka. Panzvimbo iyoyo, inokura nenzira inogona kuita kuti inzwe sekukora kana kuzara mutishu yemukaka wako.

Aya ndiwo maratidzo aunogona kuona, uchifunga kuti ILC yekutanga ingasakonzera chero zviratidzo zvachose:

• Kukora kana kuoma kwakanyanya mune imwe nzvimbo yemukaka wako panzvimbo pechidumbu chakajeka
• Kushanduka kwenzvimbo kana kunzwa kwetishu yemukaka wako
• Kukura kana kuwedzera kwemukaka kune rumwe rutivi
• Ganda rinodonha kana kuoma rinotaridzika seganda reorenji
• Mukaka unobuda pachipfuva usisiri mukaka wemukaka
• Chipfuva chinotendeuka mukati apo chisina kunge chakadaro kare
• Kushanduka kweumbozha kana saizi yemukaka
• Kurwadziwa kwenguva refu kwemukaka kana kunzwa kurwadziwa munzvimbo imwe chete

Nekuti ILC inogona kunge yakaoma kuona, zviitiko zvakawanda zvinoonekwa pakuongororwa kwemammograms usati wava nezviratidzo. Izvi ndizvo zvakanaka nekuti zvinoreva kuti kenza inowanzoonekwa pakutanga, nhanho iri nyore kurapa.

Marudzi e Invasive Lobular Carcinoma ndeapi?

Invasive lobular carcinomas yakawanda inowira murudzi rwakajairika, asi kune mamwe marudzi mashoma anogona kuzivikanwa nachiremba wako. Kunzwisisa marudzi aya kunobatsira kutungamira chirongwa chako chekurapa.

Rudzi rwakajairika runoumba anenge 80% yezviitiko zve ILC. Masero aya ekenza anokura munzira yakajairika uye anowanzova hormone receptor-positive, zvinoreva kuti anopindura zvakanaka pakurapa kwehomoni.

Marudzi mashoma anosanganisira pleomorphic lobular carcinoma, iyo inowanzova yakasimba uye ingasapindura pakurapa kwehomoni. Kunewo solid lobular carcinoma ne alveolar lobular carcinoma, asi izvi zvishoma. Pathologist wako achazivisa rudzi rwaunaro nekutarisa masampuli etishu pasi pemikroskopu.

Chii chinokonzera Invasive Lobular Carcinoma?

Sezvakaita mamwe marudzi ekenza yemukaka, ILC inokura kana masero emukaka akajairika achinja muDNA avo zvichiita kuti akure uye akakamure zvisina kudzora. Zvisinei, hatinzwisisi zvizere kuti nei izvi zvinoshanduka zvinoitika kumasero e lobular.

Zvinhu zvakati wandei zvinogona kuita kuti ILC ioneke, kunyangwe kuva nezvinhu izvi hazvirevi kuti uchava nekenza zvechokwadi:

• Zera - zviitiko zvakawanda zvinoitika muvakadzi vane makore anopfuura 50
• Nhoroondo yemhuri ye kenza yemukaka kana ovarian cancer
• Kushanduka kwemajini kunogara kwenguva refu seBRCA1 kana BRCA2
• Nhoroondo yekenza yemukaka kana mamiriro akaoma emukaka
• Kushandisa kwenguva refu kwehomoni yekutsiva
• Tishu yemukaka yakakora
• Kuonekwa kwemwaranzi kune nzvimbo yechipfuva
• Zvinhu zvehupenyu senge kunwa doro nekusaita zvemitambo

Zvakakosha kuyeuka kuti vanhu vakawanda vane izvi zvinhu zvinokonzera havazombovi nekenza yemukaka, nepo vamwe vasina zvinhu zvinozivikanwa zvinokonzera vanova nazvo. Kukura kwekenza kunonyanya kuoma uye kazhinji kunosanganisira zvinhu zvakawanda zvichiita pamwechete kwenguva yakareba.

Rini unofanira kuona chiremba nekuda kwe Invasive Lobular Carcinoma?

Unofanira kubata nachiremba wako kana ukaona chero kushanduka kwenguva refu kwemukaka wako, kunyangwe zvichinzwa zvidiki. Nekuti ILC inogona kunge yakaoma kuona, zviri nani kuti chero zvinokunetsa zviongororwe panzvimbo pekumira kuona kana zvichaenda.

Rongedza nguva nekukurumidza kana ukaona chero kushanduka kwemukaka kunogara kwenguva yakareba kupfuura mwedzi mumwe wemukadzi. Izvi zvinosanganisira nzvimbo itsva dzakakora, kushanduka kwesaizi kana chimiro chemukaka, kushanduka kwe ganda, kana kubuda kwemukaka. Kunyangwe kana wangoita mammogram yakajairika, zviratidzo zvitsva zvinofanira kuongororwa.

Kana uine nhoroondo yemhuri ye kenza yemukaka kana ovarian cancer, funga kutaura nezvekurairwa kwemajini nachiremba wako. Vanogona kukubatsira kunzwisisa njodzi yako uye kuona kana kuongororwa kwemajini kungakukodzera.

Zvinhu zvinokonzera njodzi ye Invasive Lobular Carcinoma ndeapi?

Kunzwisisa zvinhu zvinokonzera njodzi kunogona kukubatsira iwe nachiremba wako kuita sarudzo dzakachenjera pamusoro pezvirongwa zvekuongorora nekudzivirira. Mamwe mazano aunogona kudzora, nepo mamwe usingakwanisi.

Zvinhu zvausingakwanisi kuchinja zvinosanganisira zera rako, nhoroondo yemhuri, uye zvinhu zvemajini. ILC inowanzoitika muvakadzi vane makore anopfuura 50, uye kuva nehama dzapedyo dzine kenza yemukaka kana ovarian cancer zvinoita kuti njodzi yako iwedzere. Kushanduka kwemajini kunogara kwenguva refu, kunyanya BRCA2, kunogona kuwedzera njodzi ye ILC zvishoma pane mamwe marudzi ekenza yemukaka.

Zvinhu zvinogona kunge zviri mukudzora kwako zvinosanganisira kuchengetedza uremu hwakanaka, kudzora kunwa doro, kuramba uchiita zvemitambo, uye kutaura nezvenjodzi nezvikomborero zvehomoni yekutsiva nachiremba wako. Kunyangwe izvi zvinhu zvehupenyu zvichigona kubatsira kuderedza njodzi, hazvivimbiswi kudzivirira.

Matambudziko anogona kuitika e Invasive Lobular Carcinoma ndeapi?

Kana yakawanikwa pakutanga uye yakarapwa nenzira yakakodzera, vanhu vakawanda vane ILC vane migumisiro yakanaka. Zvisinei, sekunge chero kenza, kune matambudziko anogona kuitika aunofanira kuziva kuti ugone kushanda nesangano rako rezvehutano kuti uongorore uye udzore.

Chinonyanya kukosha nekenza yemukaka chero ipi zvayo ndechikwaniso chekupararira kune lymph nodes dziri pedyo kana kune dzimwe nzvimbo dzemuviri. ILC ine mukana wakakura pane mamwe marudzi ekenza yemukaka yekuonekwa mumazai maviri, panguva imwe chete kana makore gare gare. Ndosaka chiremba wako angakurudzira kuongororwa kwakawanda kwemukaka wose.

Matambudziko anokonzerwa nekurapa anogona kusanganisira zvinokonzerwa nekuvhiya, senge kushanduka kwekunzwa kwemukaka kana kufamba kwemaoko mushure mekubviswa kwe lymph node. Chemotherapy ne radiation therapy, kana zvichidiwa, zvinogona kukonzera zvinokonzerwa nekurapa kwenguva pfupi senge kuneta, kurutsa, kana kushanduka kwe ganda. Kurapa kwenguva refu kwehomoni, kunyangwe kwakakosha kwazvo, kunogona kuwedzera njodzi yekuvhara ropa kana kurasikirwa nemapfupa kune vamwe vanhu.

Matambudziko mashoma anogona kusanganisira kukura kwekenza yakasiyana gare gare muhupenyu, kunyangwe njodzi iyi iri shoma. Sangano rako rezvehutano richakurukura mamiriro ako chaiwo uye kukubatsira kunzwisisa matambudziko api anokosha kune nyaya yako.

Invasive Lobular Carcinoma inogona kudzivirirwa sei?

Kunyangwe pasina nzira yakavimbika yekudzivirira ILC, unogona kutora matanho ekuderedza njodzi yako yekenza yemukaka uye kuwana chero matambudziko pakutanga apo ari nyore kurapa.

Kushanduka kwehupenyu kunogona kubatsira kusanganisira kuchengetedza uremu hwakanaka, kuita zvemitambo nguva dzose, kudzora kunwa doro, uye kudzivisa kurapwa kwehomoni kusina basa. Kana uri kufunga nezve kurapwa kwehomoni yekutsiva kwezviratidzo zvemenopause, kurukura nezvenjodzi nezvikomborero zvayo nachiremba wako.

Kuongororwa nguva dzose ndiro dziviriro yako yakanakisa kubva kuILC. Tevedza mirairo yemammography yeboka rako rezera, uye usasiye misangano. Kana uine tishu yemukaka yakakora kana zvimwe zvinhu zvinokonzera njodzi, chiremba wako angakurudzira kuongororwa kwakawanda senge breast MRI kana ultrasound.

Kune avo vane njodzi yakakura nekuda kwenhoroondo yemhuri kana zvinhu zvemajini, matanho ekudzivirira anogona kusanganisira kuongororwa kwakawanda, kurairwa kwemajini, kana mune zviitiko zvishoma, kuvhiya kudzivirira. Izvi zvisarudzo zvinonyanya kuita zvemunhu uye zvinofanira kuitwa nekupa ruzivo kubva kune nyanzvi dzinonzwisisa mamiriro ako chaiwo.

Invasive Lobular Carcinoma inoziviswa sei?

Kuziva ILC kazhinji kunoda matanho akawanda nekuti rudzi urwu rwekenza runogona kunge rwakaoma kuona pane kuongororwa kwakajairika. Chiremba wako angatanga nekuongorora kwemuviri uye kuongorora zviratidzo zvako nenhoroondo yezvehutano.

Kuongororwa kwemifananidzo kunowanzo kusanganisira mammogram, kunyangwe ILC ingasaratidzike zvakajeka pane iyi bvunzo. Chiremba wako angakurudzirawo breast ultrasound kana MRI, izvo zvinogona kuve zvakanaka pakuzivisa kenza ye lobular. MRI inobatsira zvikuru ye ILC nekuti inogona kuratidza huwandu hwekenza uye kuongorora kenza muzai rimwe.

Kuziva kwakajeka kunoda biopsy yetishu, uko sampuli diki yetishu inokwikwiridzwa uye inotaridzwa pasi pemikroskopu. Izvi zvinogona kuitwa ne core needle biopsy, iyo inowanzoitwa muhofisi yechiremba ne local anesthesia. Pathologist achazivisa kwete chete kana kenza iripo asiwo zvinhu zvakakosha senge hormone receptor status nekukura.

Kuongororwa kwakawanda kunogona kusanganisira kuongororwa kweropa kuongorora hutano hwako hwese uye kuongororwa kwemifananidzo kuona kana kenza yakapararira kune dzimwe nzvimbo dzemuviri wako. Sangano rako rezvehutano richakurukura bvunzo imwe neimwe uye zvinorehwa nemhedzisiro yacho pachirongwa chako chekurapa.

Kurapa kwe Invasive Lobular Carcinoma ndekupi?

Kurapa kwe ILC kunonyanya kuenderana nehukuru nenzvimbo yekenza yako, kana yakapararira, nezvinhu zvayo zvebiolojia. Mashoko akanaka ndeayo ILC inowanzo pindurwa zvakanaka pakurapa, kunyanya kana yakawanikwa pakutanga.

Kuvhiya kazhinji ndiyo nhanho yekutanga uye inogona kusanganisira lumpectomy (kubvisa kenza chete nedzimwe tishu dziri pedyo) kana mastectomy (kubvisa mukadzi). Nekuti ILC inogona kuve yakakura kupfuura sezvinoita, chiremba wako angakurudzira kuvhiya kwakaitwa neMRI kuve nechokwadi chekubviswa kwakakwana. Vamwe vanhu vangadawo kubviswa kwe lymph node kuongorora kupararira kwekenza.

Vanhu vakawanda vane ILC vachawana kurapwa kwehomoni nekuti rudzi urwu rwekenza kazhinji hormone receptor-positive. Izvi zvinogona kusanganisira mishonga senge tamoxifen kana aromatase inhibitors, iyo inodzivirira homoni dzinokura kenza. Kurapa uku kunowanzoitwa kwemakore 5-10 uye kwakakosha kwazvo pakudzivirira kudzokera.

Zvichienderana nemamiriro ako chaiwo, oncologist wako angakurudzirawo chemotherapy, radiation therapy, kana mishonga inorwisa kenza. Sarudzo inotsamira pazvinhu senge saizi yetumor, kupararira kwe lymph node, uye hutano hwako hwese. Timu yako yekurapa ichaita newe kuti uite chirongwa chinokupa mukana wakanakisa wemugumisiro unokunda uchichengeta hupenyu hwako hwakanaka.

Nzira yekutarisira Invasive Lobular Carcinoma pamba?

Kutarisira ILC pamba kunosanganisira kutarisira hutano hwako hwemuviri nepfungwa uchitevera chirongwa chako chekurapa. Matanho madiki, akasimba anogona kuita musiyano mukuru pakunzwa kwako panguva yekurapa nekudzorera.

Tarisisa kudya zvokudya zvine utano zvinokupa simba uye zvinobatsira muviri wako kupora. Izvi hazvirevi kutevera kudya kwakakomba, asi kusarudza michero yakawanda, miriwo, mapuroteni asina mafuta, uye zviyo zvizere kana zvichibvira. Ramba uchinwa mvura uye usaora mwoyo kana chido chako chekudya chichichinja panguva yekurapa - izvi zvakajairika.

Kuita zvemitambo zvishoma, sezvakabvumirwa nachiremba wako, kunogona kubatsira kuderedza kuneta uye kuvandudza manzwiro ako. Izvi zvinogona kunge zviri nyore senge kufamba zvishoma kana kuita zvishoma zvekutambanudza. Zorora kana uchida, uye usanzwa mhosva yekutora nguva yekupora.

Kutarisira zvinokonzerwa nekurapa kwakakosha kune nyaradzo yako nekubudirira kwe kurapa. Chengeta chero zviratidzo uye taura nguva dzose nesangano rako rezvehutano. Vanogona kupa mishonga kana mazano ekubatsira nezvinhu senge kurutsa, kuneta, kana kurwadziwa. Usanetseka kubata navo pakati pemisangano kana uine zvinokunetsa.

Unofanira kugadzirira sei musangano wako nachiremba?

Kugadzirira musangano wako kunogona kukubatsira kuita zvakanyanya panguva yako nesangano rako rezvehutano uye kuve nechokwadi chekuti unowana ruzivo rwose rwaunoda. Tanga nekanyora mibvunzo yako usati wasvika.

Uyai ne rondedzero yemishonga yose yauri kutora, kusanganisira mishonga yekutengesa uye zvinowedzerwa. Uyaiwo nechero rekodhi dzezvehutano dzakakosha, kunyanya mammograms yapfuura kana kuongororwa kwemifananidzo yemukaka. Kana zvichibvira, uyai neshamwari yakavimbika kana nhengo yemhuri kukubatsira kuyeuka ruzivo rwakakosha rwakakurukurwa panguva yekushanya.

Funga nezvezviratidzo zvako uye pavakatanga. Gadzirira kurondedzera chero kushanduka kwawakaona mumukaka wako, kunyangwe zvichinzwa zvidiki. Chiremba wako achafanirawo kuziva nezvenhoroondo yemhuri yako ye kenza uye chero matambudziko emukaka awakambowana.

Nyora mibvunzo yako yakakosha kutanga, kana nguva ikasara shoma. Usatya kukumbira kuti vatsanangure kana usinganzwisisi chimwe chinhu - sangano rako rezvehutano rinoda kuve nechokwadi chekuti wakaziviswa zvizere nezve mamiriro ako nezvisarudzo zve kurapa.

Chii chinonyanya kukosha nezve Invasive Lobular Carcinoma?

Chinonyanya kukosha kunzwisisa nezve ILC ndechekuti rudzi rwekenza yemukaka inorapika kwazvo, kunyanya kana yakawanikwa pakutanga. Kunyangwe zvingave zvakaoma kuona pane mamwe marudzi ekenza yemukaka, kufambira mberi mukuongorora nekurapa kwakavandudza zvikuru migumisiro yevanhu vane mamiriro aya.

Kuonekwa pakutanga kuburikidza nekuongororwa nguva dzose nekutarisa kushanduka kwemukaka kunoramba iri chishandiso chako chakanakisa chemugumisiro wakanaka. Usarega hunhu hwakaomarara hwezviratidzo zve ILC kuchikonzera kuti urege kutsvaka rubatsiro rwezvehutano kana ukaona chero kushanduka mumukaka wako.

Yeuka kuti kuva neILC hakusi kukutsanangurira, uye nekurapa kwakakodzera nekutsigirwa, vanhu vakawanda vanorarama hupenyu hwazvo hwazvo, hwakanaka. Sangano rako rezvehutano riripo kukutungamira mune imwe nhanho yacho, uye kune zvinhu zvakawanda zviripo kukubatsira iwe nevanhu vaunoda kufamba ne rwendo urwu.

Mibvunzo inowanzo bvunzwa nezve Invasive Lobular Carcinoma

Mubvunzo 1: Invasive lobular carcinoma ine simba kupfuura mamwe marudzi ekenza yemukaka here?

ILC kazhinji haina simba kupfuura rudzi rwakajairika rwekenza yemukaka (invasive ductal carcinoma). Chaizvoizvo, ILC kazhinji inokura zvishoma uye inowanzova hormone receptor-positive, zvinoreva kuti inopindura zvakanaka pakurapa kwehomoni. Zvisinei, inogona kunge yakaoma kuona uye inogona kuva nenjodzi yakakura yekuonekwa mumazai maviri nekufamba kwenguva.

Mubvunzo 2: Nei mammogram yangu isina kuratidza invasive lobular carcinoma?

ILC inokura munzira yakaoma kuburikidza netishu yemukaka panzvimbo yekugadzira chidumbu chakajeka, izvo zvinoita kuti zviome kuona pane mammograms. Ndosaka chiremba wako angakurudzira kuongororwa kwakawanda senge ultrasound kana MRI, kunyanya kana uine zviratidzo kana zvinhu zvinokonzera njodzi. MRI inobatsira zvikuru pakuzivisa ILC uye kuona huwandu hwayo.

Mubvunzo 3: Ndichada mastectomy here kana ndine invasive lobular carcinoma?

Kwete zvakakosha. Vanhu vakawanda vane ILC vanogona kuita kuvhiya kunodzivirira mukadzi (lumpectomy) kunoteverwa ne radiation therapy. Sarudzo pakati pe lumpectomy ne mastectomy inotsamira pazvinhu senge saizi nenzvimbo yekenza yako, kana iri munzvimbo dzakawanda, nezvaunoda. Chiremba wako achakukurukura nezvesarudzo dzakanakisa dzenyaya yako chaiyo.

Mubvunzo 4: Kuva ne invasive lobular carcinoma kunowedzera njodzi yangu yekenza muzai rimwe here?

Hongu, ILC ine njodzi yakakura yekukura kenza muzai rimwe pane mamwe marudzi ekenza yemukaka. Ndosaka chiremba wako angakurudzira kuongororwa nguva dzose kwemukaka wose nekuongororwa kwemifananidzo. Vamwe vanhu vanosarudza kuita kuvhiya kudzivirira muzai risina kukanganiswa, asi iyi sarudzo yakakosha kwazvo inofanira kuitwa nepfungwa dzakanyanya nekutungamirwa kwenyanzvi.

Mubvunzo 5: Ndingatora hormone therapy kwenguva yakareba sei nekuda kwe invasive lobular carcinoma?

Vanhu vakawanda vane hormone receptor-positive ILC vanotora hormone therapy kwemakore 5-10 mushure mekurapa kwavo kwekutanga. Nguva chaiyo inotsamira pazvinhu zvako zvemunhu uye kuti unoshivirira sei mushonga. Oncologist wako achakubatsira kuona nguva yakakodzera yekurapa, kuenzanisa zvakanaka zve kurapa kwenguva refu nechero zvinokonzerwa nekurapa zvaunogona kuwana.