Kansa Yelobular In Situ (Lcis)
Pfupiso
Lobular carcinoma in situ (LCIS) chirwere chisingawanzoitika umo masero asingawanzoitika anoumbwa mumagaro emukaka (lobules) muzamu. Lobular carcinoma in situ (LCIS) haisi cancer. Asi kuwanikwa neLCIS kunoratidza kuti une mukana wakawedzera wekuwana cancer yezamu.
LCIS kazhinji haioneke pamamammograms. Chirwere ichi chinowanzoonekwa semugumisiro we biopsy yezamu yakaitwa nekuda kwechimwe chikonzero, sekunge kuzvimba kwezamu kunokonzera hanya kana mammogram isingawanzoitika.
Vakadzi vane LCIS vane mukana wakawedzera wekuwana cancer yezamu inopinda mumatumbu muzamu rimwe nerimwe. Kana wakawanikwa neLCIS, chiremba wako angakurudzira kuongororwa kwekenza yezamu kazhinji uye angakukumbira kuti ufungisise kurapwa kwemishonga kuderedza mukana wekuwana cancer yezamu inopinda mumatumbu.
Zviratidzo
LCIS haina zviratidzo kana zvimwe zvinoratidza. Pane kudaro, chiremba wako angawana zvisingatarisirwi kuti une LCIS—somuenzaniso, mushure mekuongororwa kwesero kubva pahukutu hwemukaka kana nzvimbo isina kunaka yakawanikwa pane mammogram.
Nguva yekunoona chiremba
'Enda kunachiremba kana ukaona kuchinja mumazamu ako, sekunge kuita bofu, nzvimbo ine ganda rakapfupika kana ganda risingawanzo kuonekwa, nzvimbo yakakura pasi peganda, kana mukaka kubva pachipfuva. Bvunza chiremba wako kuti ungafunga nezvekutarisa kenza yemazamu rinhi uye kazhinji kwenguva yakareba sei. Mapoka mazhinji anokurudzira kufunga nezvekutarisa kenza yemazamu nguva dzose uchitanga pamakore emakumi mana. Taura nachiremba wako nezvezvakakodzera kwauri.'
Zvinokonzera
Hazvina kujeka kuti chii chinokonzera LCIS. LCIS inotanga kana masero ari muchikamu chinoita mukaka (lobule) rechipfuva akatanga kuchinja kwemajini kunokonzera kuti masero aoneke asina kujairika. Masero asina kujairika anoramba ari mu lobule uye haapindi, kana kupinda, munyama yechipfuva iri pedyo.
Kana LCIS ikaonekwa mu biopsy yechipfuva, hazvirevi kuti une kenza. Asi kuva neLCIS kunowedzera njodzi yako yekenza yechipfuva uye kunoita kuti zvikwanise kuti ungatanga kenza yechipfuva inopinda.
Njovhera yekenza yechipfuva muvakadzi vakawanikwa vaine LCIS inofungidzirwa kuti iri 20 muzana. Nenzira imwe, kune vakadzi vane 100 vakawanikwa vaine LCIS, 20 vachawana kenza yechipfuva uye 80 havazoonekwi vaine kenza yechipfuva. Njovhera yekuwana kenza yechipfuva kune vakadzi kazhinji inofungidzirwa kuti iri 12 muzana. Nenzira imwe, kune vakadzi vane 100 vari munharaunda kazhinji, 12 vachawana kenza yechipfuva.
Njovhera yako pachako yekenza yechipfuva inobva pazvinhu zvakawanda. Taura nachiremba wako kuti unzwisise zvakanaka njodzi yako pachako yekenza yechipfuva.
Kuongorora
Lobular carcinoma in situ (LCIS) inogona kuwanikwa muzamu rimwe kana maviri, asi kazhinji haionekwi pane mammogram. Zvirwere izvi kazhinji zvinoonekwa sezvinhu zvisingatarisirwi kana uine biopsy yekutarisa imwe nzvimbo ine dambudziko muzamu rako.
Marudzi e biopsy yezamu anogona kushandiswa anosanganisira:
Tishu inobviswa panguva yebiopsy yako inotumirwa ku laboratori kwa vanachiremba vanokosha mukuongorora ropa ne tishu dzemuviri (pathologists) vanoongorora masero pedyo kuti vaone kana une Lobular carcinoma in situ (LCIS).
Core needle biopsy inoshandisa chubhu refu, isina mukati kuti iwane sampuli yetishu. Pano, biopsy yechinhu chinokonzera hanya muzamu iri kuitwa. Sampuli yacho inotumirwa ku laboratori kuti iongororwe ne vanachiremba, vanonzi pathologists. Vanokosha mukuongorora ropa ne tishu dzemuviri.
- Core needle biopsy. Radiologist kana chiremba anoshandisa tsono yakasimba, isina mukati kubvisa masampuli maduku etishu. Matekinoroji ekufananidzira, akadai se ultrasound kana MRI, kazhinji anoshandiswa kubatsira kutungamira tsono inoshandiswa mu core needle biopsy.
- Surgical biopsy. Chiremba anogona kuita opresheni kubvisa masero ane hanya kuti aongororwe.
Kurapa
Zvinhu zvakawanda, kusanganisira zvaunofarira iwe pachako, zvinokosha kana uchifunga kana kuti kwete kuzviita kurapwa kwe lobular carcinoma in situ (LCIS).
Kune nzira huru nhatu dzekurapa:
Kana wakazivikanwa neLCIS, chiremba wako angakurudzira bvunzo dzakawanda kuti atevedze mazamu ako kuti aone kana paine zviratidzo zvekenza. Izvi zvinogona kusanganisira:
Kurapa kwekudzivirira (chemoprevention) kunosanganisira kutora mushonga kuti udzivise ngozi yekenza yemazamu.
Sarudzo dzekurapa kwekudzivirira dzinosanganisira:
Mishonga inodzivirira mahomoni kuti arege kubatana nemasero ekensa. Mishonga yeSelective estrogen receptor modulator (SERM) inoshanda nekudzivirira estrogen receptors muma cell emazamu kuitira kuti estrogen irege kubatana nema receptors aya. Izvi zvinobatsira kuderedza kana kudzivirira kukura kwekenza yemazamu.
Tamoxifen imwe yakabvumidzwa kuderedza ngozi yekenza yemazamu muvakadzi vasati vasvika menopause nevakadzi vakapfuura menopause. Raloxifene (Evista) yakabvumidzwa kuvakadzi vakapfuura menopause kuderedza ngozi yekenza yemazamu uye kudzivirira uye kurapa osteoporosis.
Mishonga inomisa muviri kubva pakugadzira estrogen mushure memenopause. Aromatase inhibitors rudzi rwemishonga inoderedza huwandu hwe estrogen inogadzirwa mumuviri wako, ichibvisa masero ekensa emazamu mahomoni aanotoda kuti akure nekukura.
Aromatase inhibitors anastrozole (Arimidex) uye exemestane (Aromasin) imwe sarudzo yekuderedza ngozi yekenza yemazamu kuvakadzi vakapfuura menopause. Kudzidza kwakaona kuti mishonga iyi inogona kuderedza ngozi yekenza yemazamu kuvakadzi vane ngozi yakakwira, asi haisati yabvumidzwa kushandiswa neFood and Drug Administration.
Kurukurai nechikurapa chako ngozi nemabhenefiti ekutora mushonga wekudzivirira kenza yemazamu kuti uone kana iri nzira yakanaka yekurapa kwauri. Kune zvakanaka nezvakaipa zve mishonga yakasiyana, uye chiremba wako anogona kukurukura kuti mushonga upi unogona kukukodzera zvichienderana ne nhoroondo yako yekurapa.
Unogonawo kufunga nezvekuita chikamu muedzo wekurapa uchitsvaga kurapa kutsva kwe kudzivirira kenza yemazamu. Bvunza chiremba wako kana iwe ungave uri munhu anokodzera miedzo yekurapa iripo.
Kuopereta kunogona kukurudzirwa mumamiriro ezvinhu akati. Semuenzaniso, kuopereta kazhinji kunokurudzirwa kune rudzi rwakati rweLCIS rinonzi pleomorphic lobular carcinoma in situ (PLCIS). Rudzi urwu rweLCIS rinotaurwa kuti rine ngozi yakakura yekenza yemazamu kupfuura rudzi rwakajairika rwe classical.
pleomorphic lobular carcinoma in situ (PLCIS) inogona kuonekwa pane mammogram. Kana kuongororwa kwe biopsy yako kuchibvumikisa kuti une PLCIS, chiremba wako achakurudzira kuopereta. Sarudzo dzinogona kusanganisira kuita opresheni yekubvisa nzvimbo yePLCIS (lumpectomy) kana kuita opresheni yekubvisa tishu yese yemazamu (mastectomy). Pakusarudza kurapa kwakanakira iwe, chiremba wako anofunga kuti tishu yako yemazamu yakawanda sei ine PLCIS, huwandu hwezvinhu zvisina kunaka zvakawanikwa pane mammogram yako, kana uine nhoroondo yakasimba yemhuri yekenza uye zera rako.
Chiremba wako angakurudzira radiation therapy mushure mekuita lumpectomy mumamiriro ezvinhu akati. Unogona kutumirwa kuchiremba anoziva kushandisa radiation kurapa kenza (radiation oncologist) kuti aongorore mamiriro ako chaiwo uye akurukure sarudzo dzako.
Imwe sarudzo yekurapa LCIS ndeye preventive (prophylactic) mastectomy. Kuopereta uku kunobvisa mazamu ese — kwete mazamu chete akabatwa neLCIS — kuderedza ngozi yako yekuwana kenza yemazamu inopinda. Kuti uwane rubatsiro rwakanyanya rwekudzivirira kubva pakuopereta uku, mazamu ese anobviswa, nekuti LCIS inowedzera ngozi yako yekuwana kenza yemazamu mumazamu ese ari maviri. Izvi zvinogona kuva sarudzo kana uine zvimwe zvinhu zvinowedzera ngozi yekenza yemazamu, senge mutation ye gene yakaudzwa inowedzera ngozi yako, kana nhoroondo yakasimba yemhuri yerudzi urwu rwechirwere.
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Kucherechedza zvakanaka
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Kutora mushonga kuderedza ngozi yekenza (kurapa kwekudzivirira)
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Kuopereta
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Kuongorora mazamu pachako mwedzi wega wega kuti uzive mazamu ako uye kuona chero shanduko dzisingawanzoitika mumazamu
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Kuongororwa kwemazamu gore rega rega nemunhu ane hutano
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Kuongororwa kwe mammograms gore rega rega
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Kuongororwa kwemamwe maitiro ekufungidzira, senge breast MRI kana molecular breast imaging, kunyanya kana uine zvimwe zvinhu zvinowedzera ngozi yekenza yemazamu, senge nhoroondo yakasimba yemhuri yerudzi urwu rwechirwere
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Mishonga inodzivirira mahomoni kuti arege kubatana nemasero ekensa. Mishonga yeSelective estrogen receptor modulator (SERM) inoshanda nekudzivirira estrogen receptors muma cell emazamu kuitira kuti estrogen irege kubatana nema receptors aya. Izvi zvinobatsira kuderedza kana kudzivirira kukura kwekenza yemazamu.
Tamoxifen imwe yakabvumidzwa kuderedza ngozi yekenza yemazamu muvakadzi vasati vasvika menopause nevakadzi vakapfuura menopause. Raloxifene (Evista) yakabvumidzwa kuvakadzi vakapfuura menopause kuderedza ngozi yekenza yemazamu uye kudzivirira uye kurapa osteoporosis.
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Mishonga inomisa muviri kubva pakugadzira estrogen mushure memenopause. Aromatase inhibitors rudzi rwemishonga inoderedza huwandu hwe estrogen inogadzirwa mumuviri wako, ichibvisa masero ekensa emazamu mahomoni aanotoda kuti akure nekukura.
Aromatase inhibitors anastrozole (Arimidex) uye exemestane (Aromasin) imwe sarudzo yekuderedza ngozi yekenza yemazamu kuvakadzi vakapfuura menopause. Kudzidza kwakaona kuti mishonga iyi inogona kuderedza ngozi yekenza yemazamu kuvakadzi vane ngozi yakakwira, asi haisati yabvumidzwa kushandiswa neFood and Drug Administration.
Kuzvitarisira
Kana uri kunetseka nezve njodzi yako yekenza remabvu, tora matanho ekuderedza njodzi yako, akadai se:
Chengetera uremu hwakakodzera. Kana uremu hwako huripo hwakakodzera, shanda kuchengetedza uremu ihwohwo. Kana uchida kuderedza uremu, bvunza chiremba wako nezvezano dzakakodzera kuti uite izvi.
Deredza nhamba yemakorari aunodya zuva nezuva, uye zvishoma nezvishoma wedzera huwandu hwekurovedza muviri. Chinangwa chekuderedza uremu zvishoma nezvishoma — anenge 1 kana 2 mapaundi (anenge 0.5 kana 1.0 makirogiramu) pavhiki.
- Ita kurovedza muviri mazuva mazhinji evhiki. Chinangwa chekurovedza muviri kwemaminitsi anenge 30 pazuva kazhinji evhiki. Kana usati wamboita zvemuviri munguva pfupi yapfuura, bvunza chiremba wako kana zvakakodzera, uye tanga zvishoma nezvishoma.
- Chengetera uremu hwakakodzera. Kana uremu hwako huripo hwakakodzera, shanda kuchengetedza uremu ihwohwo. Kana uchida kuderedza uremu, bvunza chiremba wako nezvezano dzakakodzera kuti uite izvi.
Deredza nhamba yemakorari aunodya zuva nezuva, uye zvishoma nezvishoma wedzera huwandu hwekurovedza muviri. Chinangwa chekuderedza uremu zvishoma nezvishoma — anenge 1 kana 2 mapaundi (anenge 0.5 kana 1.0 makirogiramu) pavhiki.
- Usafume. Kana uchifuma, rega. Kana wakamboedza kurega, asi usati wabudirira, bvunza chiremba wako kuti akubatsire. Mishonga, mazano nemamwe masevhisi aripo kuti akubatsire kurega kusvuta zvachose.
- Inwa doro zvine mwero, kana zvichibvira. Dzora kunwa kwako doro kusvika kumwe chete pazuva, kana uchida kunwa.
- Deredza kurapwa kwehomoni kwekuchinja kwemwedzi. Kana uchida kutora kurapwa kwehomoni kwezviratidzo nemarwadzo ekukwegura, deredza kushandiswa kwako kusvika padyo pasi pane zvinodiwa kuti upe zororo.
Kugadzirira musangano wako
'Kana ukaona gokora kana chero shanduko isiriyo mumazamu ako, bvunza chiremba wako nguva. Kana uchinge watoongororwa nechikamu chimwe chechiremba uye uri kuita musangano wekutsvaga pfungwa yechipiri, taura nemifananidzo yako yekutanga yekurapa uye mhinduro dze biopsy kumusangano wako mutsva. Izvi zvinofanira kusanganisira mifananidzo yako yemammography, CD ye ultrasound uye ma slides egirazi kubva kubiopsy yako yemazamu. Tora mhinduro idzi kumusangano wako mutsva kana kukumbira kuti hofisi kwaakaitwa kuongororwa kwako kutumira mhinduro kudokote rako rechipiri. Heano mamwe mashoko anokubatsira kugadzirira musangano wako, uye zvaunofanira kutarisira kubva kuchiremba. Chiremba wako angakubvunza mibvunzo yakawanda. Kugadzirira kupindura kwavo kungachengetedza nguva yekufamba pamusoro penyaya dzaunoda kutaura zvakadzama. Chiremba wako angabvunza kuti: Kana biopsy yako ikaratidza LCIS, iwe ungangoda musangano wekutevera nechikamu chako. Mibvunzo yaunoda kubvunza chiremba wako nezve LCIS inosanganisira: * Nyora chero zviratidzo zvauri kuona, uye kwenguva yakareba sei. Kana uine gokora, chiremba wako achida kuziva kana wakazviona kekutanga uye kana zvichida zvakakura. * Nyora nhoroondo yako yekurapa, kusanganisira ruzivo nezve biopsies dzemazamu kare kana mamiriro ezamu asina njodzi awakazivikanwa. Taurawo nezve chero kurapwa kwemwaranzi kwaunenge wakagamuchira, kunyangwe makore apfuura. * Cherechedza chero nhoroondo yemhuri yegomarara remazamu kana rudzi rwegomarara, kunyanya mumhuri yepamberi, senge amai vako kana hanzvadzi yako. Chiremba wako achida kuziva kuti amai vako kana hanzvadzi yako vaiva nemakore mangani pavakaongororwa, pamwe nerudzi rwegomarara raiva naro. * Gadzira runyorwa rwemishonga yako. Sanganisira chero mishonga inorayirwa kana mishonga isina kurairwa yaunotora, pamwe nemavhitamini ese, zvinowedzera uye mishonga yemiti. Kana iwe uri kutora kana wakatotora kurapwa kwehomoni, taura izvi nechikamu chako. * Une gokora remazamu raunonzwa here? * Wakazviona kekutanga rini gokora iri? * Gokora rakakura here kana richishanduka nekufamba kwenguva? * Wakacherechedza chero shanduko dzisiri dzakanaka mumazamu ako, senge kubuda, kuzvimba kana kurwadziwa? * Wakapfuura menopause here? * Uri kushandisa kana wakashandisa mishonga kana zvinowedzera kuti ubvise zviratidzo zvemenopause? * Wakazivikanwa nechero mamiriro ezamu kare, kusanganisira mamiriro asina gomarara? * Wakazivikanwa nechero mamiriro ekurapa? * Une nhoroondo yemhuri yegomarara remazamu here? * Iwe kana hama dzako dzevakadzi vakakomberedza makambotariswa nezve shanduko dzejeni reBRCA here? * Wakambowana kurapwa kwemwaranzi here? * Chii chikafu chako chemazuva ese, kusanganisira kunwa doro? * Uri munhu ane simba here? * LCIS inowedzera sei njodzi yangu yegomarara remazamu? * Ndine chero zvinhu zvinowedzera njodzi yegomarara remazamu here? * Kazhinji sei ndinofanira kuongororwa nezve gomarara remazamu? * Rudzii rwetekinoroji yekuongorora ichava inonyanya kushanda mumuitiro wangu? * Ndiri munhu anokodzera mishonga inoderedza njodzi yegomarara remazamu here? * Ndeapi mamiriro akaoma kana matambudziko emishonga iyi? * Chii chinodhaka chaunokurudzira kwandiri, uye nei? * Uchandiongorora sei kuti uone zvinokonzerwa nekurapa? * Ndiri munhu anokodzera kuvhiya kwekuvimba here? * Kazhinji, kurapwa kwaunokurudzira kunobudirira sei muvakadzi vane chirwere chakafanana neni? * Ndeapi mararamiro anogona kubatsira kuderedza njodzi yangu yegomarara? * Ndinoda pfungwa yechipiri here? * Ndinofanira kuona mushandi we genetic here?'