Lupus

Lupus chirwere chinoitika kana masimba emuviri wako ekudzivirira achirova ma tishu nema organs emuviri wako (chirwere che autoimmune). Kutsvuka kunokonzerwa ne lupus kunogona kukanganisa masisitimu akawanda emuviri - kusanganisira majoini ako, ganda, itsvo, masero eropa, uropi, mwoyo nemapapu.

Lupus inogona kunge yakaoma kuziva nekuti zviratidzo nezvimwe zvinoratidza kazhinji zvinoita se zve zvirwere zvimwe. Chiratidzo chinonyanya kuzivikanwa che lupus - ganda rakapfava pachiso rinotaridzika semapapiro e chipembere richivhurwa pamatama ese ari maviri - rinoitika muvakawanda asi kwete mune zvese zviitiko zve lupus.

Vamwe vanhu vanoberekwa vane tsika yekuwana lupus, iyo inogona kukonzera hutachiona, mishonga chaiyo kana kunyange chiedza chezuva. Kunyangwe pasina mushonga we lupus, kurapwa kunogona kubatsira kudzora zviratidzo.

Hapana nyaya mbiri dzeLupus dzakafanana chaizvo. Zviratidzo nezvimwe zvirwere zvinogona kuuya kamwe kamwe kana kukura zvishoma nezvishoma, zvinogona kunge zviri zvishoma kana zvakakomba, uye zvinogona kunge zviri zvechinguva kana zvechigarire. Vanhu vakawanda vane Lupus vane chirwere chidiki chinoratidzwa nechikamu - chinonzi flares - apo zviratidzo nezvimwe zvirwere zvinoita zvakanyanya kwenguva, zvino zvakanaka kana kutopera zvachose kwenguva.

Zviratidzo nezvimwe zvirwere zveLupus zvaunonzwa zvichaenderana nezvikamu zvemuviri zvakabatwa nechirwere ichi. Zviratidzo nezvimwe zvirwere zvakajairika zvinosanganisira:

• Kushaya simba
• Kupisa
• Kurwadziwa kwemashure, kuoma uye kuzvimba
• Rash ine chimiro chebhatafurai pachiso inofukidza makwati nechidimbu chemhino kana rashes kune dzimwe nzvimbo mumuviri
• Zvirwere zve ganda zvinooneka kana kuwedzera nekufumurwa nezuva
• Minwe neminwe yemunwe inochinja kuva chena kana bhuruu kana yakafumurwa nekunotonhora kana panguva dzekumanikidzwa
• Kushomeka kwekufema
• Kurwadziwa kwepfupa
• Meso akaoma
• Kurwadziwa kwemusoro, kusanzwisisa uye kurasikirwa nekuyeuka

Ona chiremba wako kana ukawana utachiona husina kujekeswa, fivha inoramba iripo, kurwadziwa kwenguva refu kana kuneta.

Sezvo iri chirwere chinorwisa muviri, lupus inoitika kana masero ako ekuzvidzivirira akasvika pakurwisa tishu dzako dzakajairika mumuviri. Zvinoratidza kuti lupus inokonzerwa nekusanganiswa kwemajini ako nemagariro ako.

Zvinoita sokuti vanhu vane chirwere che lupus vanogona kurwara kana vakasangana nechimwe chinhu munzvimbo yavakagara chinogona kutanga lupus. Zvisinei, konzero ye lupus mune zviitiko zvizhinji haizivikanwi. Zvimwe zvinhu zvinogona kutanga lupus zvinosanganisira:

• Zuva. Kuonekwa nezuva kunogona kutanga maronda eganda re lupus kana kutanga kuita kwemukati muvanhu vane njodzi.
• Zvirwere. Kuva nezvirwere kunogona kutanga lupus kana kukonzera kudzokazve mune vamwe vanhu.
• Mishonga. Lupus inogona kutangwa nemhando dzakati dzemishonga yekudzikisa ropa, mishonga yekudzivirira kuita zviitiko zvekuvhiringika kwepfungwa uye mishonga inorwisa mabhakitiriya. Vanhu vane lupus inokonzerwa nemishonga vanowanzoramba vakanaka kana vakarega kutora mushonga. Zvishoma, zviratidzo zvinogona kuramba zvichionekwa kunyangwe mushonga wacho wabviswa.

Zvinhu zvinogona kuwedzera njodzi yako yekurwara ne lupus zvinosanganisira:

• Bonde rako. Lupus inowanzowanikwa muvakadzi.
• Age. Kunyangwe lupus ichikanganisa vanhu vemazera ese, kazhinji inowanzoonekwa pakati pemakore ekuma15 kusvika ku45.
• Rudzi. Lupus inowanzowanikwa mumaAfrican Americans, Hispanics neAsian Americans.

Kutsamwiswa kunokonzerwa ne lupus kunogona kukanganisa nzvimbo dzakawanda dzemuviri wako, kusanganisira:

• Itsvo. Lupus inogona kukonzera kukuvara kwakakomba kwetsvo, uye kukundikana kwetsvo chimwe chezvikonzero zvikuru zverufu pakati pevanhu vane lupus.
• Uropi nehurongwa hwepfungwa hwepamusoro. Kana uropi hwako hukanganiswa ne lupus, unogona kuwana kurwadziwa kwemusoro, kuzvinzwa uchizvitsauka, kuchinja kwemifungo, matambudziko ekukuona, uye kunyange kurova kweropa kana kuita zvikwata. Vanhu vakawanda vane lupus vanosangana nematambudziko ekurangarira uye vangave nekuoma kutaura pfungwa dzavo.
• Ropa nemidziyo yeropa. Lupus inogona kukonzera matambudziko eropa, kusanganisira kuwanda kwemasero matsvuku eropa ane hutano (anemia) uye kuwedzera njodzi yekubuda ropa kana kuomerera kweropa. Inogona zvakare kukonzera kutsamwa kwemidziyo yeropa.
• Mapapu. Kuva ne lupus kuwedzera mikana yako yekuwana kutsamwa kwe lining yechipfuva, izvo zvinogona kuita kuti kufema kuve kurwadza. Kubuda ropa mumapapu uye pneumonia zvinokwanisikawo.
• Moyo. Lupus inogona kukonzera kutsamwa kwemhasuru yemoyo wako, arteries kana membrane yemoyo. Njodzi yechirwere che cardiovascular uye kurova kwemoyo inowedzera zvakanyanyawo.

Kuongorora lupus kunonetsa nekuti zviratidzo nezvimwe zvinoratidza zvinosiyana zvikuru kubva kune munhu kuenda kune mumwe munhu. Zviratidzo nezvimwe zvinoratidza zve lupus zvinogona kuchinja nekufamba kwenguva uye zvinowirirana nezvezvirwere zvakawanda. Hapana bvunzo imwe chete inogona kuongorora lupus. Kusanganiswa kwekuyedza ropa nekwemukaka, zviratidzo nezvimwe zvinoratidza, uye zviwanikwa zvekuongororwa kwemuviri zvinoita kuti pave nekuongororwa. Kuongorora ropa nekwemukaka kunogona kusanganisira: Kana chiremba wako achifungidzira kuti lupus iri kukanganisa mapapu ako kana mwoyo, anogona kukurudzira: Lupus inogona kukuvadza itsvo dzako nenzira dzakasiyana-siyana, uye kurapwa kunogona kusiyana, zvichienderana nerudzi rwekukuvadzwa kunoitika. Muzviitiko zvimwe, zvakakosha kuyedza sampuli diki yetsvo kuti uone kuti kurapwa kwakanakisa kungave kwei. Sampuli inogona kuwanikwa ne tsono kana kuburikidza nekucheka duku. Kuongororwa kwe ganda kunowanzoitwa kusimbisa kuongororwa kwe lupus inokanganisa ganda. * Kuverenga kwakakwana kweropa. Bvunzo iyi inoyera huwandu hwesero dzvitsvuku, masero machena eropa uye maplatelet pamwe chete nehuwandu hwehemoglobin, puroteni iri mumasero matsvuku eropa. Mhedzisiro inogona kuratidza kuti une anemia, iyo inowanzoitika mu lupus. Huwandu hwakaderera hwemasero machena eropa kana maplatelet hunogona kuitika mu lupus zvakare. * Kuyerera kwemasero matsvuku eropa. Bvunzo iyi yeropa inotsanangura kuyerera kwemasero matsvuku eropa anogara pasi pechubhu muawa. Kuyerera kukurumidza kupfuura kwenguva dzose kunogona kuratidza chirwere chemuviri wose, sekunge lupus. Kuyerera kwe sedimentation hakusi kwakakosha kune chirwere chimwe chete. Inogona kukwira kana uine lupus, chirwere, chimwe chimiro chekuzvimba kana kenza. * Kuongororwa kwetsvo nechiropa. Kuongorora ropa kunogona kuongorora kuti itsvo nechiropa zvako zviri kushanda zvakanaka sei. Lupus inogona kukanganisa nhengo idzi. * Kuongororwa kwemukaka. Kuongororwa kwesampuli yemukaka wako kunogona kuratidza kuwedzera kwehuwandu hwepuroteni kana masero matsvuku eropa mumukaka, izvo zvinogona kuitika kana lupus yakakanganisa itsvo dzako. * Bvunzo yeAntinuclear antibody (ANA). Bvunzo yakanaka yekuvepo kwema antibodies aya - akagadzirwa ne immune system yako - inoratidza immune system yakakurudzirwa. Kunyangwe vanhu vakawanda vane lupus vane bvunzo yakanaka ye antinuclear antibody (ANA), vanhu vakawanda vane ANA yakanaka havaina lupus. Kana ukaedzwa uchinge uine ANA, chiremba wako anogona kukurudzira kuongororwa kwakanyanya kwe antibody. * X-ray yepaburi. Mufananidzo wepaburi rako unogona kuratidza mimvuri isina kujairika inoratidza mvura kana kuzvimba mumapapu ako. * Echocardiogram. Bvunzo iyi inoshandisa mafungu ekuita mifananidzo yehupenyu hwemoyo wako unorova. Inogona kutarisa matambudziko ne valves dzako nezvimwe zvikamu zvemoyo wako.

Kurapa chirwere che lupus kunoenderana nezviratidzo zvako. Kutsanangura kana uchifanira kurapwa uye mishonga yekushandisa kunoda hurukuro yakangwarira yemabhenefiti nenjodzi nachiremba wako.

Sezviratidzo zvako zvichiwedzera uye zvichipera, iwe nachiremba wako munogona kuwana kuti muchafanira kuchinja mishonga kana huwandu. Mishonga inonyanya kushandiswa kudzora lupus inosanganisira:

Biologics. Rudzi rwakasiyana remushonga, belimumab (Benlysta) inopiwa ne intravenous, inoderedzawo zviratidzo zve lupus kune vamwe vanhu. Zvinokonzeresa zvinosanganisira kurutsa, manyoka uye hutachiona. Zvisingawanzoitiki, kuwedzera kwekuora mwoyo kunogona kuitika.

Rituximab (Rituxan, Truxima) inogona kubatsira kune vamwe vanhu avo mishonga yakawanda isina kubatsira. Zvinokonzeresa zvinosanganisira kuita allergic reaction kune intravenous infusion uye hutachiona.

Mukuedzwa kwevanachiremba, voclosporin yakaratidzwa kuva inoshanda pakurapa lupus.

Mishonga yakawanda inogona kushandiswa kurapa lupus iri kudzidzwa ikozvino, kusanganisira abatacept (Orencia), anifrolumab nevamwe.

• Mishonga isingapedzi kuzvimba (NSAIDs). Mishonga isingapedzi kuzvimba (NSAIDs) inowanikwa pasina chinyorwa, senge naproxen sodium (Aleve) uye ibuprofen (Advil, Motrin IB, nevamwe), inogona kushandiswa kurapa marwadzo, kuzvimba uye fivha inobatanidzwa ne lupus. NSAIDs ine simba yakawanda inowanikwa ne chinyorwa. Zvinokonzeresa zve NSAIDs zvinogona kusanganisira kubuda ropa mudumbu, matambudziko etsinga uye kuwedzera njodzi yematambudziko emwoyo.
• Mishonga inorwisa malaria. Mishonga inonyanya kushandiswa kurapa malaria, senge hydroxychloroquine (Plaquenil), inokanganisa immune system uye inogona kubatsira kuderedza njodzi yekuzvimba kwe lupus. Zvinokonzeresa zvinogona kusanganisira kusagadzikana kwemudumbu uye, zvisingawanzoitiki, kukuvara kwe retina yeziso. Kuongororwa kwemaziso nguva nenguva kunokurudzirwa kana uchitora mishonga iyi.
• Corticosteroids. Prednisone nemhando dzakasiyana dze corticosteroids inogona kurwisa kuzvimba kwe lupus. Huwandu hwakawanda hwe steroids senge methylprednisolone (Medrol) kazhinji hinoshandiswa kudzora chirwere chakakomba chinobatanidza itsvo nehuropi. Zvinokonzeresa zvinosanganisira kuwedzera uremu, kuvhunduka nyore, kuonda kwemapfupa, kuwedzera kweropa, chirwere cheshuga uye kuwedzera njodzi yehutachiona. Njodzi yezvinokonzeresa inowedzera nehuwandu hwakawanda uye kurapwa kwenguva refu.
• Immunosuppressants. Mishonga inodzora immune system inogona kubatsira mumamiriro ezvinhu akakomba e lupus. Mienzaniso inosanganisira azathioprine (Imuran, Azasan), mycophenolate (Cellcept), methotrexate (Trexall, Xatmep, nevamwe), cyclosporine (Sandimmune, Neoral, Gengraf) uye leflunomide (Arava). Zvinokonzeresa zvinogona kusanganisira kuwedzera njodzi yehutachiona, kukuvara kwechiropa, kuderedza kubereka uye kuwedzera njodzi yekenza.
• Biologics. Rudzi rwakasiyana remushonga, belimumab (Benlysta) inopiwa ne intravenous, inoderedzawo zviratidzo zve lupus kune vamwe vanhu. Zvinokonzeresa zvinosanganisira kurutsa, manyoka uye hutachiona. Zvisingawanzoitiki, kuwedzera kwekuora mwoyo kunogona kuitika.

Rituximab (Rituxan, Truxima) inogona kubatsira kune vamwe vanhu avo mishonga yakawanda isina kubatsira. Zvinokonzeresa zvinosanganisira kuita allergic reaction kune intravenous infusion uye hutachiona.

Tora matanho ekutarisira muviri wako kana uine lupus. Matanho ari nyore anogona kukubatsira kudzivirira kuwedzera kwe lupus, uye kana zvikaitika, kubata zvakanaka nezviratidzo nezvimwe zvaunonzwa. Edza ku:

• Ona chiremba wako nguva dzose. Kuve nekuongororwa nguva dzose panzvimbo pekungoona chiremba wako chete kana zviratidzo zvako zvakanyanya zvinogona kubatsira chiremba wako kudzivirira kuwedzera, uye zvinogona kubatsira pakugadzirisa zvinetso zvehutano hwemazuva ose, senge kushushikana, kudya uye kurovedza muviri izvo zvinogona kubatsira kudzivirira matambudziko e lupus.
• Iva wakangwara nezvezuva. Nekuti chiedza che ultraviolet chinogona kutanga kuwedzera, pfeka nguo dzinodzivirira — senge ngowani, hembe refu uye marefu — uye shandisa sunscreen ine sun protection factor (SPF) yeanenge 55 nguva dzose paunobuda kunze.
• Ita kurovedza muviri nguva dzose. Kurovedza muviri kunogona kubatsira kuchengetedza mapfupa ako akasimba, kuderedza njodzi yekurwisa kwemoyo uye kukurudzira hutano hwese.
• Usafume. Kusvuta kunowedzera njodzi yako yechirwere chemwoyo uye kunogona kuipa zvakanyanya migumisiro ye lupus pamoyo nemidziyo yeropa.
• Dya kudya kwakanaka. Kudya kwakanaka kunosimbisa michero, miriwo uye zviyo zvizere. Dzimwe nguva unogona kunge uine zvipingamupinyi zvekudya, kunyanya kana uine BP yakakwira, kukuvara kweitsvo kana matambudziko egastrointestinal.
• Bvunza chiremba wako kana uchida zvinowedzerwa zve vitamin D ne calcium. Kune uchapupu hunoratidza kuti vanhu vane lupus vanogona kubatsirwa ne vitamin D inowedzerwa. Kuwedzerwa kwe calcium kunogona kukubatsira kusangana nehuwandu hwezuva nezuva hwakakurudzirwa hwe 1,000 milligrams kusvika ku 1,200 milligrams — zvichienderana nezera rako — kubatsira kuchengetedza mapfupa ako akasimba.