Varume 2
Pfupiso
Multiple endocrine neoplasia, rudzi rwechipiri, inozivikanwawo seMEN 2, chirwere chisingawanzoitiki. Inokonzera zvironda muzvikonzero zve thyroid neparathyroid, adrenal glands, miromo, muromo, maziso uye turakiti yekudya. Kuongororwa kwemajini kunogona kuwana jini rachinja rinokonzera MEN 2. Vanopa utano vanogona kurapa matambudziko ehutano ayo jini rinogona kukonzera.
MEN 2 chirwere chinogona kuwanikwa kubva kuvabereki. Izvi zvinoreva kuti vanhu vane jini rachinja vanogona kuripa kuvana vavo. Mwana mumwe nemumwe ane mukana we50% wekuwana chirwere.
Kune marudzi maviri eMEN 2:
- MEN 2A. Iyi inozivikanwawo seMEN 2A yakajairwa kana kuti Sipple syndrome. Inokonzera kenza ye medullary thyroid uye zvironda zvisina kenza zveparathyroid glands ne adrenal glands.
- MEN 2B. Rudzi urwu rweMEN 2 rwusingawanzoitiki. Inokonzera kenza ye medullary thyroid, zvironda zvisina kenza zve adrenal gland, uye zvironda zvisina kenza pam miromo, parurimi uye muturakiti yekudya. MEN 2B haikonzere matambudziko neparathyroid glands.
Zviratidzo
Zviratidzo zveMEN 2 zvinoenderana nerudzi rwenyoka. Vanhu vane MEN 2B vane chitarisiko chakasiyana. Vanogona kuva nehutu pamuta, miromo nemaziso. Vanowanzo kureba uye marefu nemaoko marefu nemakumbo. Zvinotevera zviratidzo zvinogona kuwirirana nerudzi rwehutachiona. Kenza yeMedullary thyroid: Zvikwambo muhuro kana mutsipa Kunetseka kufema kana kumira Kuita kwerurimi Manyoka Hyperplasia yeParathyroid, inozivikanwawo se primary hyperparathyroidism: Kurwadziwa kwemhasuru nemapfupa Tsinga Kusuruvara Matambudziko ekurangarira Matombo emuitsvo Zvirwere zveAdrenal, zvinozivikanwawo se pheochromocytoma: BP yakakwira Kutemwa kwemoyo nekukurumidza Kuzvidya mwoyo Misoro Zviratidzo zvinogona kukonzerwa nehutachiona hwe thyroid huchimanikidza tishu dziri pedyo kana kuburitswa kwehomoni dzakawanda mumuviri. Vamwe vanhu vane kenza ye medullary thyroid vangave vasina zviratidzo. Kana uri kuve nezvimwe chezviratidzo izvi, taura nachiremba wako.
Nguva yekunoona chiremba
Kana uine chimwe chezviratidzo izvi, taura nachiremba wako.
Zvinokonzera
MEN 2 chirwere chinogara kuri muropa. Izvi zvinoreva kuti munhu ane jini rachinja rinogona kukonzera MEN 2 anogona kupasa jini iroro kuvana vake.
Vanhu vazhinji vangavewo munhu wekutanga mumhuri dzavo kuva nedambudziko iri. Vanhu vanoonekwa vane kenza ye medullary thyroid vanoongororwa nguva dzose kuti vaone kana vane MEN 2.
Matambudziko
MEN 2 inogona kukonzera kuti mazamu eparathyroid aise calcium yakawanda muropa. Izvi zvinozivikanwa se primary hyperparathyroidism. Mazamu eparathyroid ari muchiuno chako. Calcium yakawandisa muropa inogona kukonzera matambudziko mazhinji, kusanganisira mapfupa asina simba, anodanwa kuti osteoporosis, matombo emuitsvo uye kuve nechido chekuenda kunzvimbo kazhinji. Kenza ye medullary thyroid inooneka sechibereko pachii thyroid kana muchiuno. Zvinogona kuoma kumeza kana chitsitsinho chiri chikuru kana zvimwe zviratidzo kana kenza ikapararira kunze kwechiuno. Vanhu vane MEN 2 vanogonawo kuva nechirwere chinonzi pheochromocytoma. Ichi chirwere chinoita kuti pave nemahumha asina kenza pachikamu che adrenal gland. Mazamu e adrenal ari pamusoro pemitsvo. Aya mahumbha anogona kuburitsa mahomoni anokonzera kuwedzera kweropa, kupererwa neperspiration nezvimwe zviratidzo.
Kudzivirira
Kuongororwa kwemajini kunoshandiswa kuona kana munhu ane gene yakachinja inokonzera MEN 2. Vana vemumwe munhu ane iyi gene yakachinja vanogona kuiwana voga ndokuva neMEN 2. Vabereki nehama vanogonawo kuva ne gene yakachinja kunyangwe vasina zviratidzo. Kana mumwe munhu wemhuri yenyu akaonekwa aine MEN 2, mushandi wehutano wenyu angakurudzira kuti imi nevamwe vemhuri yenyu muongororwe majini. Izvi ndizvo nekuti MEN 2 inogona kurapwa kana kutarisirwa kuburikidza no kubvisa gland ye thyroid pakutanga kweupenyu. Kuongororwa kwezvironda zve parathyroid kana adrenal zvinogonawo kubatsira. Kana pasina kuchinja kwemajini kwawanikwa mune vemhuri, kazhinji hapana mimwe miedzo yekuongorora inodiwa. Zvisinei, kuongororwa kwemajini hakutsvaki kuchinja kose kwemajini eMEN 2. Kana MEN 2 isingaonekwi muvanhu vanogona kuva nayo, ivo nevemhuri yavo vachaita bvunzo dzeropa ne mifananidzo nguva nenguva kuti vaone zviratidzo zverwisiso.
Kuongorora
Kuongorora multiple endocrine neoplasia, rudzi 2, inozivikanwawo seMEN 2, mushandi wako wehutano achaita bvunzo yemuviri. Achatarisa nhoroondo yako yezvokurapa nenhoroondo yemhuri. Achaitawo bvunzo yemajini kuti aone kana une shanduko yejini inokonzera MEN 2. Bvunzo yeropa neyeweti uye bvunzo dzekuona zvinhu zvinogona kuitwa. Idzi dzinogona kusanganisira:
-mazinga eCalcitonin muropa -Calcium yeropa -mazinga eParathyroid hormone -bvunzo yeweti kana yeplasma ye catecholamines ne metanephrines -Magnetic resonance imaging (MRI) -Computerized tomography (CT) scan -Ultrasound scan
Kurapa
MuMEN 2, zvironda zvinogona kukura paitiroiri, mapaparathyroid ne adrenal glands. Aya maronda anogona kukonzera mamiriro akasiyana-siyana, ese anogona kurapwa. Aya mamiriro ekurapa anogona kusanganisira:
- Kenza ye medullary thyroid. Kenza yeitiroiri, kusanganisira kenza yakapararira kune dzimwe nhengo dzemuviri, inorapwa kuburikidza nekubvisa gland yeitiroiri ne lymph nodes dziri kumativi ayo nekuvhiya. Mishonga inogona kushandiswawo kana chirwere chakapararira uye chisingagone kubviswa nekuvhiya.
- Kuwedzera kwe parathyroid. Glands dze parathyroid dzinogona kukura uye kugadzira homoni ye parathyroid yakawanda. Kurapa kwenguva dzose ndekuvhiya kubvisa zvese kana chikamu cheglands dze parathyroid dzakakura, uchisiya chero glands dzisingakanganiswi.
- Zvironda zve adrenal. Kune marudzi aya ezvironda, mushandi wako wehutano anogona kukurudzira kubvisa imwe kana ese maviri adrenal glands, zvichienderana nezvinoratidzwa pa CT kana MRI.
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