Chii Chinonzi Mixed Connective Tissue Disease? Zviratidzo, Zvinokonzera, & Kurapa

Mixed connective tissue disease (MCTD), chirwere chisina kujairika che autoimmune chinobatanidza zviratidzo zvemamwe marwere e connective tissue. Sisitimu yako yekudzivirira muviri inorwisa zvinyama zvako zvakajairika, zvichikonzera kuzvimba mumatumbu akawanda kusanganisira tsandanyama, majoini, ganda, nemapapu.

Chirwere ichi chinonzi kudaro nekuti chine zviratidzo zvakafanana ne lupus, scleroderma, ne polymyositis panguva imwe chete. Kunyange zvazvo izvi zvinganzwikwa zvakawanda, kunzwisisa MCTD kunogona kukubatsira kuziva zviratidzo pakutanga wobva washanda nesangano rako rezvehutano kuti urirape zvakanaka.

Chii Chinonzi Mixed Connective Tissue Disease?

Mixed connective tissue disease chirwere che autoimmune umo sisitimu yekudzivirira muviri wako inorwisa muviri wako. Inorwisa zvikamu zvinobatanidza zvinhu, izvo zvinhu zvinobatsira muviri wako kusimba se majoini, tsandanyama, neatumbu.

Chinonyanya kusiyanisa MCTD ndiko kuvapo kweantibodies inonzi anti-U1-RNP antibodies muropa rako. Aya ma antibodies anoshanda semuchina unobatsira vanachiremba kusiyanisa MCTD nemamwe marwere akafanana. Chirwere ichi chakatsanangurwa kekutanga muna 1972, zvichiita kuti chive chitsva muzvinachiremba.

MCTD inotapura vanhu vanenge 2 kusvika ku3 pavagumi ve100,000, zvichiita kuti ive isingawanzoitika. Inowanzoonekwa muvakadzi vane makore ari pakati pe20 ne50, kunyange zvazvo inogona kuitika pane chero uremu. Chirwere ichi chinowanzoitika zvishoma nezvishoma, nezviratidzo zvichionekwa kwemwedzi kana makore.

Ndeapi Zviratidzo zveMixed Connective Tissue Disease?

Zviratidzo zveMCTD zvinogona kusiyana zvikuru kubva kumunhu kuenda kune mumwe munhu nekuti zvinokanganisa matunhu akawanda emuviri. Zviratidzo zvepakutanga zvinowanzoita kurwadziwa kwemajoini, kushaya simba kwetsandanyama, uye kuchinja kwe ganda kungaita sekusina kubatana pakutanga.

Heano zviratidzo zvakajairika zvaunogona kuwana:

• Raynaud's phenomenon: Minwe yako neminwe yemunwe inochinja kuva chena, bhuruu, kana tsvuku kana yakatarisana nekunotonhora kana kushushikana
• Mazamu akabvaruka: Mazamu ako angaonekwa akabvaruka, kunyanya mangwanani
• Kurwadziwa kwemajoini nekukora: Kwakafanana ne arthritis, kunokanganisa majoini akawanda
• Kushaya simba kwetsandanyama: Kunyanya mumafudzi ako, maoko epamusoro, chiuno, nemabvi
• Kuchinja kwe ganda: Makashu pachiso chako, maoko, kana mamwe mativi
• Kuneta: Kuneta kwenguva refu kunoshanduka nekuzorora
• Kushaya mweya: Kunetseka kufema, kunyanya panguva yekurovedza muviri

Vamwe vanhu vanonzwawo zviratidzo zvisingawanzoitika sekunetsa kumeza, maziso akaoma nemuromo, kana kurasikirwa nevhudzi. Kusanganiswa nekuoma kwezviratidzo kunogona kuchinja nekufamba kwenguva, nemamwe maitiro akaipa kupfuura mamwe.

Chii Chinokonzera Mixed Connective Tissue Disease?

Chikonzero chaicho cheMCTD hachizivikanwi, asi vatsvakurudzi vanotenda kuti chinobva pakusanganiswa kwezvikonzero zvemajini nezvinokonzera zvakatipoteredza. Majini ako haakonzere chirwere ichi zvakananga, asi anogona kukugadzirira kuti uchinje.

Zvinhu zvakati wandei zvinogona kuita kuti MCTD iitike kune vanhu vanogona kuita chirwere ichi:

• Zvirwere zvehutachiona: Zvirwere zvakaita seEpstein-Barr virus zvinogona kutanga kupindura kwe autoimmune
• Zvinhu zvinokuvadza zvakatipoteredza: Kuonekwa ne silica guruva kana mamwe makemikari
• Zvinhu zvemahomoni: Kuwanda kwakawanda muvakadzi kunoratidza kuti mahomoni anogona kutamba basa
• Zvinhu zvemajini: Mamwe majeni anowedzera njodzi
• Kushushikana: Kushushikana kwemuviri kana kwepfungwa kunogona kutanga zviratidzo

Zvakakosha kunzwisisa kuti MCTD haisi chirwere chinopfuudzwa uye haugone kuchitora kubva kune mumwe munhu. Chirwere ichi chinoitika kana sisitimu yako yekudzivirira muviri ichivhiringidzika ichitanga kurwisa zvinyama zvakajairika izvo zvaifanira kudzivirirwa.

Rini Unofanira Kuona Chiremba neMixed Connective Tissue Disease?

Unofanira kuona chiremba kana uine zviratidzo zvinoramba zvichiitika zvinoratidza chirwere che autoimmune, kunyanya kana zviratidzo zvakawanda zvichiitika pamwe chete. Kuongororwa nekurapwa pakutanga kunogona kubatsira kudzivirira matambudziko uye kuvandudza hupenyu hwako.

Tsvaka rubatsiro rwezvehutano nekukurumidza kana ukaona aya mazano ekunyevera:

• Kurwadziwa kwemajoini nekubvaruka kwenguva refu kupfuura mavhiki mashoma
• Raynaud's phenomenon iri yakakomba kana inokanganisa mabasa ezuva nezuva
• Kushaya simba kwetsandanyama kusina kujairika kunokanganisa kugona kwako kuita mabasa ezuva nezuva
• Makashu eganda asingapindure kurapwa kwezvinhu zvinowanikwa pasina chinyorwa chechiremba
• Kuneta kwenguva refu kunodzora mabasa ako ezuva nezuva
• Kunetseka kufema kana kurwadziwa pachipfuva
• Matambudziko ekumeza chikafu kana zvinwiwa

Kana uine kushaya mweya kwenguva pfupi, kurwadziwa pachipfuva, kana zviratidzo zvematambudziko etsinga sekubvaruka mumakumbo ako kana kuchinja mukuita kwemukati, tsvaka rubatsiro rwekukurumidza rwezvehutano. Izvi zvinogona kuratidza matambudziko akakomba anoda kurapwa nekukurumidza.

Ndeapi Njodzi dzeMixed Connective Tissue Disease?

Kunyangwe chero munhu anogona kuwana MCTD, zvinhu zvakati wandei zvinogona kuwedzera mukana wako wekuwana chirwere ichi. Kunzwisisa aya njodzi kunogona kukubatsira kuramba uchiri kuziva zviratidzo zvinogona kuitika uye kutsvaka rubatsiro rwezvehutano rwakakodzera.

Njodzi huru dzinosanganisira:

• Bonde: Vakadzi vane mukana wekuwana MCTD wakakura kupfuura varume kanopfuura 8 kusvika ku10
• Uremu: Inowanzoongororwa pakati pemakore 20 ne50
• Nhoroondo yemhuri: Kuva nehama dzine autoimmune diseases kunogona kuwedzera njodzi
• Rudzi: Inowanzoitika mune dzimwe nharaunda, kusanganisira maAfrican Americans nevaHispanic
• Mamwe autoimmune diseases: Kuva ne autoimmune disease imwe kunowedzera njodzi yekuwana mamwe
• Kuonekwa nezvinhu zvakatipoteredza: Kuonekwa ne silica, mamwe makemikari, kana zvirwere

Kuva neaya njodzi hazvirevi kuti iwe uchave uine MCTD. Vanhu vakawanda vane njodzi dzakawanda havazombovi nechirwere ichi, nepo vamwe vane njodzi shoma vachiwana.

Ndeapi Matambudziko Anogona Kuitika eMixed Connective Tissue Disease?

MCTD inogona kukanganisa matunhu akawanda emuviri wako, zvichikonzera matambudziko akakomba kana isina kurapwa zvakanaka. Zvakanaka ndechekuti nerapira rakakodzera nekutarisa, matambudziko akawanda anogona kudzivirirwa kana kuderedzwa.

Matambudziko akajairika iwe nesangano rako rezvehutano muchacherechedza anosanganisira:

• Pulmonary hypertension: Kuderera kweropa mumapapu kunogona kunetsa moyo wako
• Kuzvimba kwemapapu: Kuita mavara kana kuzvimba kwemapapu kunokanganisa kufema
• Matambudziko emoyo: Kuzvimba kwetsandanyama yemoyo kana zvinyama zvakapoteredza
• Matambudziko etsinga: Kunyange zvisingawanzoitika se lupus, matambudziko etsinga anogona kuitika
• Kushaya simba kwetsandanyama kwakakomba: Kushaya simba kunogona kukanganisa kufamba
• Matambudziko ekugaya: Matambudziko ekumeza kana kuita kwematumbu

Matambudziko asingawanzoitika asi akakomba anosanganisira pulmonary hypertension yakakomba, inogona kutyisidzira hupenyu kana isina kuonekwa nekurapwa pakutanga. Ndosaka kuchengetedza nekutarisa nesangano rako rezvehutano zvakakosha kwazvo pakubata matambudziko usati asvika pakakomba.

Mixed Connective Tissue Disease Inooongororwa Sei?

Kuongorora MCTD kunogona kuva kwakaoma nekuti ine zviratidzo zvakafanana nemamwe autoimmune diseases. Chiremba wako achazvishandisa kusanganiswa kwekuongorora kwemuviri, bvunzo yeropa, uye dzimwe nguva kuongorora mifananidzo kuti awane chirwere.

Maitiro ekuongorora anowanzoita matanho akawanda. Kutanga, chiremba wako achawana nhoroondo yakakwana yezvehutano uye aite kuongorora kwemuviri, achitarisa zviratidzo zvakafanana sekubvaruka kwemaoko, kuchinja kwe ganda, uye kushaya simba kwetsandanyama.

Bvunzo yeropa inokosha pakuzivisa uye ichabatanidza:

• Anti-U1-RNP antibodies: Bvunzo huru yeMCTD
• Antinuclear antibodies (ANA): Kazhinji inenge iri positive mune speckled pattern
• Zviratidzo zvekuzvimba: Bvunzo dzakadai seESR neCRP yekuyera kuzvimba
• Muscle enzymes: Kuwedzera kwemwero kunogona kuratidza kuzvimba kwetsandanyama
• Kuverenga kweropa kwakakwana: Kutarisa anemia kana mamwe matambudziko eropa

Chiremba wako anogona kurayirawo kuongorora mifananidzo senge chest X-rays kana CT scans kuti aongorore mapapu ne moyo. Dzimwe nguva bvunzo dzakawedzerwa senge pulmonary function tests kana echocardiograms zvinodiwa kuti aongorore kuita kwematumbu.

Kurapa kweMixed Connective Tissue Disease Kudii?

Kurapa kweMCTD kunotarisa pakudzora kuzvimba, kudzora zviratidzo, uye kudzivirira kukuvara kwematumbu. Sezvo chirwere ichi chinokanganisa vanhu vakasiyana nenzira dzakasiyana, chirongwa chako cherapira chichagadzirirwa zviratidzo zvako zvakakosha nezvinodiwa.

Sangano rako rezvehutano rinogona kushandisa kusanganiswa kwemishonga nezviitiko zveupenyu. Chinangwa ndechekukubatsira kunzwa zvakanaka uchivhara matambudziko emangwana kubva muchirwere.

Sarudzo dzekurapa dzakajairika dzinosanganisira:

• Corticosteroids: Prednisone kana mishonga yakafanana yekuderedza kuzvimba nekukurumidza
• Immunosuppressive drugs: Methotrexate, azathioprine, kana mycophenolate yekudzikamisa sisitimu yekudzivirira muviri
• Antimalarial drugs: Hydroxychloroquine yezviratidzo zve ganda nemajoini
• Biologics: Kurapa kwakatarwa kwakakosha kune zviitiko zvakakomba
• Calcium channel blockers: YeRaynaud's phenomenon
• Physical therapy: Kusimbisa simba retsandanyama uye kunyanyisa majoini

Kurapa kunowanzo tanga nemishonga yakapfava uye kunokwira kumishonga yakasimba kana zvichidiwa. Chiremba wako achakucherechedza zvakanyanya kuvandudzwa kwezviratidzo uye zvinogona kuitika zvinokonzerwa nemishonga.

Ungadzikamisa Sei Mixed Connective Tissue Disease Kumba?

Kudzikamisa MCTD kumba kunosanganisira kuchinja mararamiro uye nzira dzekuzvichengeta dzinotibatsira kuderedza zviratidzo uye kuvandudza hupenyu hwako. Aya maitiro anoshanda zvakanaka kana akasanganiswa nerapira rako rakarayirwa nachiremba.

Heano matanho aunogona kutora kuti ubatsire kudzora chirwere chako:

• Dzivirira kunotonhora: Pfukuta magorovhosi nemasokisi anodziya kudzivirira Raynaud's attacks
• Rovedza muviri nguva dzose: Mabasa akaoma senge kushambira kana kufamba anobatsira kuchengetedza simba retsandanyama
• Zorora zvakakwana: Edza kurara maawa 7-9 uye zorora kana zvichidiwa
• Dya zvokudya zvakakwana: Tarisa pazvokudya zvinorwisa kuzvimba uye chengetedza uremu hwakanaka
• Dzora kushushikana: Shandisa nzira dzekudzikama senge kufungisisa kana kufema kwakadzama
• Usafume: Kusvuta kunowedzera matambudziko ekufamba kweropa nematambudziko emapapu
• Ramba uchinwa mvura yakawanda: Inwa mvura yakawanda kubatsira nekuneta nehutano hwese

Kudzivirirwa kwezuva zvakakoshawo sezvo mamwe mishonga yeMCTD inogona kukugadzirira kuti uve munhu anonzwa zuva zvakanyanya. Shandisa sunscreen, pfeka nguo dzinodzivirira, uye deredza kuonekwa nezuva panguva dzezuva rakasimba.

Mixed Connective Tissue Disease Inogona Kudzivirirwa Sei?

Parizvino, hapana nzira inozivikanwa yekudzivirira MCTD sezvo chikonzero chaicho chisingazivikanwi. Zvisinei, unogona kutora matanho ekuderedza njodzi yekuwedzera kwezviratidzo nematambudziko kana uchinge uine chirwere ichi.

Kunyangwe kudzivirira chirwere chekutanga kuchikosha, unogona kutarisa pakudzivirira matambudziko uye kudzora zvinokonzera. Kudzivisa zvinokonzera zvinozivikanwa senge kushushikana kwakanyanya, zvirwere, uye zvinhu zvakatipoteredza zvinogona kubatsira kuderedza huwandu hwezviratidzo.

Kuchengetedza hutano hwakanaka kuburikidza ne kurovedza muviri nguva dzose, kudya kwakanaka, kurara zvakakwana, uye kudzora kushushikana kunogona kutsigira sisitimu yako yekudzivirira muviri nehutano hwese. Kana uine nhoroondo yemhuri ye autoimmune diseases, kuziva zviratidzo zvinogona kuitika kunogona kubatsira pakuzivisa nekurapa pakutanga.

Ungagadzirira Sei Kune Chiremba Wako?

Kuagadzirira zvakanaka kune chiremba wako kunogona kubatsira kuve nechokwadi chekuti unowana zvakawanda kubva pakushanya kwako uye kupa sangano rako rezvehutano ruzivo rwavanotoda kuti vakubatsire zvakanaka.

Usati wasvika pachiremba, nyora zviratidzo zvako zvese, kusanganisira pavakatanga uye chii chinoita kuti zvive nani kana zvakaipa. Chengetedza dhiari yezviratidzo kwevhiki kana mbiri kana zvichibvira, uchicherechedza maitiro ezviratidzo zvako.

Uya neaya zvinhu zvakakosha kune chiremba wako:

• Rondedzero yemishonga yese iripo, zvinowedzerwa, nemavhitamini
• Nhoroondo yakakwana yezvehutano, kusanganisira zvirwere zvakapfuura nekuvhiyiwa
• Nhoroondo yemhuri ye autoimmune kana connective tissue diseases
• Rondedzero yemibvunzo yaunoda kubvunza chiremba wako
• Chero bvunzo dzawapfuura kana marekodhi ezvehutano
• Ruzivo rweinshurensi nekuzivikanwa

Funga nezvekukoka shamwari yakavimbika kana nhengo yemhuri kuti ikubatsire kuyeuka ruzivo rwakataurwa panguva yekushanya kwacho. Usanetseka kubvunza mibvunzo kana kukumbira kujeka kana chimwe chinhu chisingaoneki.

Chii Chinonyanya Kukosha Nezve Mixed Connective Tissue Disease?

Mixed connective tissue disease chirwere che autoimmune chinogona kurapwa chinokanganisa matunhu akawanda emuviri. Kunyange zvazvo zvingaita sekutyisa pakutanga, kunzwisisa chirwere chako uye kushanda pedyo nesangano rako rezvehutano kunogona kukubatsira kurarama zvakanaka neMCTD.

Chinhu chakakosha chokuyeuka ndechekuti MCTD inokanganisa munhu wese nenzira dzakasiyana, uye chirongwa chako cherapira chinofanira kugadzirirwa zvinodiwa nezviratidzo zvako. Nerapira rakakodzera, kuchinja mararamiro, uye kuzvidzivirira, vanhu vakawanda vane MCTD vanorarama hupenyu hwazvo hwese, hwakazara.

Kuongororwa nekurapwa pakutanga ndizvo zvinokosha pakudzivirira matambudziko uye kuchengetedza hupenyu hwako. Ramba uine hukama nesangano rako rezvehutano, taura chokwadi nezviratidzo zvako, uye usanetseka kutsvaka rubatsiro kana uchida. Hausi wega munzira iyi, uye kune kurapa kwakakosha kuripo kukubatsira kudzora chirwere chako.

Mibvunzo InowanzoBvunzwa Nezve Mixed Connective Tissue Disease

Mixed Connective Tissue Disease Inouraya Here?

MCTD kazhinji haiurayi, uye vanhu vakawanda vane chirwere ichi vane hupenyu hwenguva refu kana hwakafanana nehupenyu hwenguva refu. Huwandu hwemakore gumi hwekupona huri pamusoro pe90%. Zvisinei, matambudziko akakomba senge pulmonary hypertension yakakomba inogona kutyisidzira hupenyu kana isina kurapwa zvakanaka. Kucherechedza nguva dzose nekurapwa kwakakodzera zvinowedzera zvakanyanya zvibereko.

Mixed Connective Tissue Disease Inogona Kupora Here?

Hongu, vamwe vanhu vane MCTD vanowana nguva yekupora umo zviratidzo zvinowedzera kana kupera kwenguva pfupi. Zvisinei, chirwere ichi chinowanzova chekare, zvinoreva kuti chinodiwa kurapwa nguva dzose. Vamwe vanhu vanogona kuva nenguva refu ine zviratidzo zvishoma, kunyanya nerapira rakakodzera.

MCTD Inosiyana Sei neLupus?

Kunyangwe MCTD ne lupus zvine zvimwe zvakafanana, MCTD inoratidzwa nekuvapo kwe anti-U1-RNP antibodies uye kazhinji ine matambudziko mashoma etsinga kupfuura lupus. MCTD inowanzova nekushaya simba kwetsandanyama uye inowanzoita pulmonary hypertension. Kusanganiswa kwezviratidzo kubva kune mamwe marwere e connective tissue ndiko kunosiyanisa MCTD.

Pamwe Pamuviri Unogona Kukanganisa Mixed Connective Tissue Disease Here?

Pamwe pamuviri unogona kukanganisa zviratidzo zveMCTD, nevakadzi vamwe vachiwana kuvandudzika nepo vamwe vachiwana zviratidzo zvakakomba. Zvakakosha kushanda pedyo ne rheumatologist wako ne obstetrician kana uri kuronga kuva nepamuviri kana uri nepamuviri. Mamwe mishonga yeMCTD inogona kudikanwa kugadziriswa panguva yepamuviri.

Kuchinja Kweupenyu Kwakakosha Kwazvo Pakudzora MCTD Ndeapi?

Kuchinja kwakakosha kwazvo kweupenyu kunosanganisira kuzvidzivirira kubva kunotonhora kudzivirira Raynaud's attacks, kuchengetedza kurovedza muviri nguva dzose kuchengetedza simba retsandanyama, kurara zvakakwana, kudzora kushushikana zvakanaka, uye kudzivisa kusvuta. Kudya zvokudya zvinorwisa kuzvimba uye kuramba uchinwa mvura kunogona kubatsira kudzora zviratidzo uye kutsigira hutano hwese.