Zvirwere zveNeuroendocrine Tumors? Zviratidzo, Zvinokonzera, & Kurapa

Zvirwere zveNeuroendocrine tumors ndizvirimwa zvinoitika kubva kumasero chaiwo mumusoro wenyu anogadzira mahomoni uye anobatsira mukutonga mabasa akakosha emuviri. Aya masero, anonzi neuroendocrine cells, anoshanda senhangemutange pakati pehurongwa hwako hwemitsipa nemaglands anogadzira mahomoni.

Kunyangwe zita racho richinzwa rakaoma, funga nezvezvirwere izvi sezvirimwa zvinogona kukanganisa maitiro emuviri wako pakugadzira nekushandisa mahomoni. Zvizhinji zve neuroendocrine tumors zvinokura zvishoma nezvishoma uye vanhu vazhinji vanorarama hupenyu hwazvo hwese, hwakanaka, ne kurapwa kwakakodzera nekutarisa.

Chii chinonzi neuroendocrine tumors?

Neuroendocrine tumors inoumbwa kana neuroendocrine cells ikatanga kukura zvisina kujairika. Aya masero chaiwo akapararira mumusoro wenyu wese, asi anowanikwa zvakanyanya munzira yako yekudya, mapapu, uye pancreas.

Zvirwere izvi zvinogona kuva benign (zvisina kenza) kana malignant (kenza). Zvizhinji zveizvi zvirwere zvinoshanda, zvinoreva kuti zvinogadzira mahomoni akawanda anogona kukonzera zviratidzo zvinonyatsoonekwa. Zvimwe hazvishandi uye zvinogona kusakonzera zviratidzo kusvikira zvakura zvakakura zvakakwana kuti zvidzvinyirire nhengo dziri pedyo.

Aya matumor haawanzoitiki, anokanganisa vanhu vanenge 6-7 pavagumi ve100,000 gore rega rega. Zvisinei, vanachiremba vari kuawana kazhinji ikozvino nekuda kwemaitiro akanaka ekufungisisa uye kuwedzera kuziva.

Ndeapi zviratidzo zve neuroendocrine tumors?

Zviratidzo zvinosiyana zvakanyanya zvichienderana nekwakagara tumor uye kana ichigadzira mahomoni. Vanhu vazhinji vane zviratidzo zvakajairika izvo zvinogona kunyengerwa nyore nyore nezvimwe zvirwere.

Heano zviratidzo zvakajairika zvaunogona kuona:

• Kurwadziwa kwenguva refu mudumbu kana kurwadziwa kunoramba kuripo
• Kuchinja mukuita kwemadumbu, kusanganisira manyoka anoramba aripo kwemavhiki
• Kurasikirwa nehuremu zvisinganzwisisiki pasina kuedza kurasikirwa nehuremu
• Kuita kwekutsvuka apo chiso chako nemutsipa zvinotendeuka tsvuku kamwe kamwe uye kunzwa kupisa
• Kufema kana kuoma kufema kunoratidzika kunge kuchibva kune imwe nzvimbo
• Kupuruzira kwemoyo kana kurova kwemoyo kwasingajairiki
• Kuneta kunorasikirwa nekuzorora

Vamwe vanhu vane zvinonzi vanachiremba kuti "carcinoid syndrome," izvo zvinoitika kana zvirwere zvinogadzira mahomoni zvichisunungura zvinhu muropa rako. Izvi zvinogona kukonzera kuita kwekutsvuka, manyoka, uye matambudziko ekufema.

Zviratidzo zvisingawanzoitiki zvinogona kusanganisira kuzvimba kwepande, kuchinja kwehuga, kana maronda emudumbu. Chinhu chikuru chekuyeuka ndechekuti zviratidzo kazhinji zvinokura zvishoma nezvishoma uye zvinogona kuva zvishoma pakutanga.

Ndeapi marudzi e neuroendocrine tumors?

Vanachiremba vanoronga neuroendocrine tumors zvichienderana nekwavanokura uye nekukurumidza kwavanokura. Nzvimbo kazhinji inotsanangura zviratidzo zvaunogona kuona uye kuti ndeapi maitiro ekurapa anoshanda zvakanaka.

Marudzi akanyanya kuwanda anosanganisira:

• Gastroenteropancreatic (GEP) tumors dzinoitika mudumbu rako, matumbo, kana pancreas
• Lung neuroendocrine tumors dzinoumbwa munzira yako yekufema
• Pancreatic neuroendocrine tumors, kusanganisira insulinomas uye gastrinomas
• Carcinoid tumors, dzakawanda dzinoitika mumatumbo ako maduku kana appendix

Vanachiremba vanotarisawo aya matumor kubva kuG1 kuenda kuG3 zvichienderana nekukurumidza kwemasero ari kugovaniswa. G1 tumors inokura zvishoma nezvishoma, G2 tumors inokura nekukurumidza, uye G3 tumors inokura nekukurumidza uye inoda kurapwa kwakasimba.

Timu yako yekuchengetedza utano ichaona rudzi rwakakosha uye giredhi kuburikidza nemiedzo yakasiyana-siyana, izvo zvinovabatsira kugadzira chirongwa chekurapa chakakodzera mamiriro ako.

Chii chinokonzera neuroendocrine tumors?

Chikonzero chaicho chezvizhinji zve neuroendocrine tumors hachizivikanwi, asi vatsvakurudzi vanotenda kuti zvinoitika kana neuroendocrine cells ichipfuura kuchinja kwemajini kunovakonzera kukura zvisina kujairika. Aya kuchinja kazhinji kunoitika zvisingatarisirwi nguva nenguva.

Zvinhu zvakati wandei zvinogona kuita kuti zvikure:

• Kuchinja kwemasero ane chekuita nezera, sezvo aya matumor akajairika muvanhu vane makore anopfuura 50
• Zvirwere zvemajini zvinowanikwa semhuri senge Multiple Endocrine Neoplasia (MEN) syndromes
• Nhoroondo yemhuri ye neuroendocrine tumors kana zvirwere zvine hukama
• Zvimwe zvirwere zvinokanganisa kugadzirwa kweacid mudumbu

Muitiro usina kujairika, vanhu vanogona kugara vane majini anochinja anowedzera njodzi yavo zvakanyanya. Aya ma syndromes anowanikwa semhuri anongoita 5-10% ye neuroendocrine tumors dzese.

Chinonyanya kukosha, aya matumor haakonzerwi nezvinhu zvekugara senge kudya, kusvuta, kana kushushikana. Hauite chero chinhu chakakonzera mamiriro aya, uye hapana chikonzero chekuzvipa mhosva kana uri kurwara ne neuroendocrine tumor.

Rini unofanira kuona chiremba nezve neuroendocrine tumors?

Unofanira kubata nehutano hwako kana uine zviratidzo zvinoramba zvichiitika kwemavhiki anopfuura mashoma, kunyanya kana zvichikanganisa hupenyu hwako hwezuva nezuva. Kunyangwe aya zviratidzo zvingave nezvikonzero zvakawanda, zviri nani nguva dzose kuazviongorora.

Tsvaka rubatsiro rwekurapa nekukurumidza kana ukaona:

• Kurwadziwa kwakanyanya mudumbu kunorasikirwa ne mishonga yekutengesa
• Manyoka anoramba aripo kwemavhiki anopfuura maviri
• Kurasikirwa nehuremu zvisinganzwisisiki kweanopfuura mapaundi gumi
• Kuita kwekutsvuka kazhinji pamwe nezvimwe zviratidzo
• Kunetseka kufema kana kufema kuri kuwedzera kuipa

Usamirire kana uri kuona zviratidzo zvakakomba kana zviratidzo zvakawanda zvichiitika pamwe chete. Chiremba wako anogona kubatsira kuona kana miedzo yakawanda inodiwa.

Yeuka, zvirwere zvakawanda zvinogona kukonzera zviratidzo zvakafanana, saka edza kusazvinetseka zvakanyanya usati wataura nechiremba. Kuongororwa pakutanga kazhinji kunotungamira kumigumisiro iri nani kana kurapwa kuchidikanwa.

Ndeapi njodzi dze neuroendocrine tumors?

Zvinhu zvakati wandei zvinogona kuwedzera mukana wako wekuwana neuroendocrine tumor, kunyangwe kuva nenjodzi hazvirevi kuti iwe uchaiwana zvechokwadi. Kunzwisisa izvi zvinhu zvinogona kukubatsira iwe nechikurapa chako kuti murambe muri vakangwarira nezviratidzo zvinogona kuitika.

Njodzi huru dzinosanganisira:

• Makore anopfuura 50, apo kuchinja kwemasero kunova kwakajairika
• Nhoroondo yemhuri ye neuroendocrine tumors kana zvirwere zvemajini zvine hukama
• Zvirwere zvinowanikwa semhuri senge Multiple Endocrine Neoplasia syndromes
• Zvimwe zvirwere zvemudumbu zvinoderedza kugadzirwa kweacid
• Kuva muAfrica American, izvo zvinowedzera njodzi zvishoma nezvimwe marudzi

Zvimwe zvirwere zvisingawanzoitiki zvemajini zvinowedzera njodzi zvakanyanya, kusanganisira von Hippel-Lindau chirwere uye neurofibromatosis rudzi 1. Aya mamiriro anowanikwa semhuri uye kazhinji anosanganisira marudzi akawanda etumor.

Kuva nenjodzi imwe kana kupfuura hazvirevi kuti uchave ne neuroendocrine tumor. Vanhu vazhinji vane njodzi havambovi neaya matumor, nepo vamwe vasina njodzi inozivikanwa vachiwana.

Ndeapi matambudziko anogona kuitika e neuroendocrine tumors?

Zvizhinji zve neuroendocrine tumors zvinokura zvishoma nezvishoma uye zvinokonzera matambudziko anogona kutongwa, kunyanya kana akawanikwa pakutanga. Zvisinei, matambudziko amwe anogona kuitika kana zvirwere zvisina kurapwa kana zvichigadzira mahomoni akawanda.

Matambudziko akajairika aunogona kuona anosanganisira:

• Carcinoid syndrome kubva kuzvirwere zvinogadzira mahomoni zvichikonzera kutsvuka nemanyoka
• Kuita kwekudzvinyirira kwematumbo kana zvirwere mumatumbo ako zvakakura zvakakwana
• Matambudziko emakona emoyo kubva ku carcinoid syndrome kwenguva refu
• Kusawirirana kwehuga kubva ku pancreatic tumors
• Maronda emudumbu kubva ku gastrin-producing tumors

Matambudziko asingawanzoitiki asi akakomba anogona kusanganisira carcinoid crisis, iyo inosanganisira kutsvuka kwakanyanya, kuchinja kweropa, uye kuoma kufema. Izvi kazhinji zvinoitika chete nezvirwere zvakakura zvinogadzira mahomoni.

Mashoko akanaka ndeayo kurapwa kwazvino kunogona kudzivirira kana kutonga zvizhinji zvematambudziko zvinobudirira. Timu yako yekuchengetedza utano ichakutarisa pedyo uye ichashandura kurapwa sezvinodiwa kuderedza chero matambudziko.

Neuroendocrine tumors inogona kudzivirirwa sei?

Zvinosuruvarisa, hapana nzira yakaratidzwa yekudzivirira zvizhinji zve neuroendocrine tumors sezvo kazhinji zvinoitika nekuda kwekuchinja kwemajini zvisingatarisirwi. Zvisinei, unogona kutora matanho ekutsigira hutano hwako hwese uye kuwana chero matambudziko pakutanga.

Heano zvaunogona kuita:

• Chengeta kuongororwa nguva dzose nehutano hwako
• Taura nezviratidzo zvinoramba zvichiitika kana zvisingajairiki nekukurumidza
• Tevedza mazano ekutarisa kana uine nhoroondo yemhuri
• Funga nezvekurairwa kwemajini kana uine njodzi dzinowanikwa semhuri
• Rarama hupenyu hunogara hwakajairika nechikafu chakanaka nekuita zvemitambo nguva dzose

Kana uine syndrome inozivikanwa yemajini inowedzera njodzi yako, chiremba wako anogona kukurudzira miedzo chaiyo yekutarisa kana kuongororwa kazhinji. Iyi nzira yekutanga inogona kubatsira kuwana zvirwere pakutanga kana zviri nyore kurapa.

Kunyangwe usingakwanisi kudzivirira aya matumor zvachose, kuramba uchiyeuka muviri wako uye kuchengetedza kutaurirana kwakavhurika nechikurapa chako kunokupa mukana wakanakisa wekuwana pakutanga nekurapa kwakabudirira.

Neuroendocrine tumors inoziviswa sei?

Kuziva neuroendocrine tumors kazhinji kunoda miedzo yakawanda yakasiyana nekuti zviratidzo zvinogona kufanana nezvimwe zvirwere zvakawanda. Chiremba wako achatanga nenhoroondo yakakwana yekurapa nekuongororwa kwemuviri kunzwisisa zviratidzo zvako.

Maitiro ekuongorora kazhinji anosanganisira:

• Miedzo yeropa yekutarisa mahomoni uye zviratidzo zve tumor
• Miedzo yemukaka yekuyera zvigadzirwa zvekuparara kwehomoni
• CT kana MRI scans yekuwana uye kuyera matumor
• Kuongororwa kwakasarudzika senge octreotide scans inotarisa neuroendocrine cells
• Endoscopy procedures yekuongorora nzira yako yekudya
• Biopsy yekusimbisa kuongororwa uye kuona giredhi re tumor

Chiremba wako anogona kuraira miedzo chaiyo yehomoni zvichienderana nezviratidzo zvako. Semuenzaniso, kana uri kunetseka nehuga, vachaongorora mazinga e insulin. Kana uri kuona kutsvuka nemanyoka, vachaongorora zvinhu zvine chekuita ne carcinoid syndrome.

Maitiro ese ekuongorora anogona kutora mavhiki akawanda kana kunyange mwedzi, izvo zvinogona kunzwa zvakashata. Zvisinei, kuwana kuongororwa kwakakwana kwakakosha pakugadzira chirongwa chekurapa chakakodzera mamiriro ako chaiwo.

Kurapa kwe neuroendocrine tumors ndechii?

Kurapa kwe neuroendocrine tumors kunoenderana nezvinhu zvakati wandei kusanganisira nzvimbo ye tumor, saizi, giredhi, uye kana ichigadzira mahomoni. Vanhu vazhinji vanoita zvakanaka ne kurapwa, uye mamwe matumor anogona kupora zvachose.

Chirongwa chako chekurapa chingasanganisira:

• Kuopereta kubvisa tumor, iyo kazhinji ndiyo kurapwa kunonyanya kufarirwa kwezvirwere zvakagara munzvimbo imwe
• Somatostatin analogs kudzora kugadzirwa kwehomoni uye kudzikisa kukura kwe tumor
• Mishonga yekurapa inorwisa masero e tumor chaiwo
• Chemotherapy yezvirwere zvakasimba kana zvakapararira
• Radiation therapy kudzikisa matumor kana kuderedza zviratidzo
• Kurapa kwakatariswa ku chiropa kana zvirwere zvakapararira ku chiropa

Kune zvirwere zvinogadzira mahomoni, chiremba wako achaisa pfungwa pakudzora zviratidzo panguva yekurapa tumor pachayo. Izvi zvinogona kusanganisira mishonga yekutonga manyoka, kutsvuka, kana matambudziko ehuga.

Vanhu vazhinji vane zvirwere zvinokura zvishoma nezvishoma vanogona kutarisirwa nekuongororwa nguva dzose nemiedzo yeropa pasina kurapwa pakarepo. Nzira iyi, inonzi active surveillance, inokubvumira kudzivirira zvinokonzerwa ne kurapwa uchivimbisa kuti tumor haisi kukura kana kuchinja.

Maitiro ekutonga neuroendocrine tumors pamba?

Kutonga hupenyu ne neuroendocrine tumor kunosanganisira kurapwa kwemishonga uye nzira dzezuva nezuva. Vanhu vazhinji vanoona kuti vanogona kuchengetedza hupenyu hwavo hwakanaka nemamwe marongero uye nzira dzekuzvichengeta.

Heano mazano anobatsira ekutonga zuva nezuva:

• Chengeta bhuku rezviratidzo kuti utevedze maitiro nezvinokonzera
• Dya zvidyo zviduku, zvakawanda kuti ubatsire nezviratidzo zve digestive
• Rambai muchinwa mvura yakawanda, kunyanya kana muri kuona manyoka
• Dzivisa zvokudya nezvinwiwa zvinokonzera kutsvuka
• Ita nzira dzekudzora kushushikana senge kufema kwakadzika kana kufungisisa
• Zorora zvakakwana uye chengeta nguva yekurara yakajairika

Kana uri kurwara ne carcinoid syndrome, ungada kudzivisa zvimwe zvokudya senge chizi chakakura, doro, kana zvokudya zvinopisa zvinogona kukonzera kutsvuka. Timu yako yekuchengetedza utano inogona kupa mazano chaiwo ekudya.

Rambai muchibatanidzwa nemapoka ekutsigira kana masevhisi ekurairwa kana muri kunzwa kuneta. Vanhu vazhinji vanoona zviri nyore kutaura nevamwe vanonzwisisa zviri kuitika kwavari.

Unofanira kugadzirira sei kuonana kwako nachiremba?

Kugadzirira kuonana kwako kunogona kukubatsira kuti uwane zvakanyanya kubva panguva yako nehutano hwako uye kuve nechokwadi chekuti unowana ruzivo rwose rwaunoda. Kugadzirira kwakanaka kunobatsirawo chiremba wako kunzwisisa mamiriro ako zviri nani.

Usati waenda kuonana kwako:

• Rondedzera zviratidzo zvako zvese, kusanganisira pavakatanga uye kakawanda kwavanouya
• Uye ne mishonga yese iripo, kusanganisira zvinowedzerwa nemishonga yekutengesa
• Gadzira mibvunzo nezve kuongororwa kwako, sarudzo dzekurapa, uye zvinotarisirwa
• Unganidza zvinyorwa zve kurapa zvakakosha kubva kune vamwe vanachiremba
• Funga nezvekutora nhengo yemhuri kana shamwari yekutsigira uye kubatsira yekurangarira ruzivo

Nyora mibvunzo chaiyo yaunoda kubvunza, senge rudzi rwe tumor yaunayo, kuti ndeapi maitiro ekurapa aripo, uye zvinotarisirwa kuenda mberi. Usazengurire kukumbira kuti zvinhu zvisanzwisisike zvinotsanangurwa.

Yeuka kuti iyi ndiyo hutano hwako, uye une kodzero yekunzwisisa mamiriro ako zvizere. Chiremba akanaka acatora nguva yekupindura mibvunzo yako uye kukubatsira kunzwa wakasununguka nechirongwa chako chekurapa.

Chii chinonyanya kukosha nezve neuroendocrine tumors?

Neuroendocrine tumors ndizvirwere zvinogona kutongwa zvinokanganisa masero anogadzira mahomoni mumusoro wenyu wese. Kunyangwe kugamuchira kuongororwa uku kunogona kunzwa kwakanyanya, vanhu vazhinji vane aya matumor vanorarama hupenyu hwazvo hwese, hwakanaka, ne kurapwa kwakakodzera nekutarisa.

Zvinhu zvinonyanya kukosha zvekuyeuka ndizvo zvekutanga zvinokura zvishoma nezvishoma, maitiro ekurapa akawanda aripo, uye kuwana pakutanga kazhinji kunotungamira kumigumisiro iri nani. Timu yako yekuchengetedza utano ichaita newe kugadzira chirongwa chekurapa chakakodzera mamiriro ako chaiwo.

Usazengurire kubvunza mibvunzo, tsvaka mamwe mazano kana zvichidiwa, uye tsigira hurongwa hwako rwekutsigira panguva iyi. Nemishonga yakakurumbira yemazuva ano nemaitiro ekutarisa, tarisiro yevanhu vane neuroendocrine tumors inoramba ichikura.

Mibvunzo inobvunzwa kazhinji nezve neuroendocrine tumors

Neuroendocrine tumors nguva dzose here kenza?

Kwete, neuroendocrine tumors inogona kuva benign (isina kenza) kana malignant (kenza). Zvizhinji zveaya matumor zvinokura zvishoma nezvishoma uye zvinogona kusapararira kune dzimwe nzvimbo dzemuviri wako. Chiremba wako achaona kana tumor yako chaiyo iri benign kana malignant kuburikidza nemiedzo yakasiyana-siyana kusanganisira biopsy nekuongorora kwemuviri.

Neuroendocrine tumors inogona kupora zvachose here?

Hungu, zvizhinji zve neuroendocrine tumors zvinogona kupora zvachose, kunyanya kana zvikawanikwa pakutanga uye hazvina kupararira kunze kwenzvimbo yadzo yekutanga. Kuopereta kunogona kazhinji kubvisa tumor yese, zvichikonzera kupora zvachose. Kunyangwe kupora kuchikosha, vanhu vazhinji vanorarama kwemakore akawanda nekudzora zviratidzo zvinobudirira nekurapa.

Ndichada kurapwa pakarepo here kana ndikawana kuongororwa?

Kwete zvakakosha. Zvizhinji zve neuroendocrine tumors zvinokura zvishoma nezvishoma zvinogona kutarisirwa nekuongororwa nguva dzose nekuongororwa pasina kurapwa pakarepo. Nzira iyi, inonzi active surveillance kana watchful waiting, inokubvumira kudzivirira zvinokonzerwa ne kurapwa uchivimbisa kuti tumor haisi kuchinja. Chiremba wako achakurudzira kurapwa pakarepo kana tumor ikakura, ichikonzera zviratidzo, kana ichigadzira mahomoni akawanda.

Kushushikana kana kudya kunogona kukonzera neuroendocrine tumors here?

Kwete, neuroendocrine tumors haakonzerwi nekushushikana, kudya, kana zvinhu zvekugara. Aya matumor anokura nekuda kwekuchinja kwemajini muma cell anowanzoitika zvisingatarisirwi nguva nenguva. Kunyangwe zvimwe zvokudya zvingakonzera zviratidzo kune vanhu vane matumor anogadzira mahomoni, hazvikonzeri matumor pachawo kuti akure.

Ndichafanira kuenda kuonana kwenguva yakareba sei uye miedzo?

Marongero ekutevera anosiyana zvichienderana nerudzi rwe tumor yako, kurapwa, uye hutano hwese. Vanhu vazhinji vanoda kuonana kwemavhiki matatu kusvika ku6 pakutanga, izvo zvinogona kupararira kamwe kana kaviri pagore sezvo nguva ichifamba. Chiremba wako anogona kuraira miedzo yeropa nguva dzose nekuongorora kwemuviri kuti aongorore mamiriro ako. Huwandu chaihwo huchagadzirwa ne mamiriro ako chaiwo uye kuti uri kupindura sei kurapwa.