Chii Chinonzi Paget's Disease Yemazamu? Zviratidzo, Zvinokonzera, & Kurapa

Paget's disease yemazamu chirwere chisina kujairika chekenza yemazamu chinotambudza ganda renipple neareola. Chirwere ichi chinowanikwa mu1-3% yezvirwere zvese zvekenza yemazamu uye kazhinji chinoitika pamwe chete nekenza iri mukati memazamu.

Ungacherechedza kuchinja kunotaridzika sek eczema kana kuti ronda panzvimbo yenyupple. Kunyange zvazvo zviratidzo izvi zvingatyisa, kunzwisisa zvamuri kutambura nazvo kunokubatsira kutora matanho chaiwo ekurapa kwakakodzera.

Chii Chinonzi Paget's Disease Yemazamu?

Paget's disease yemazamu inoitika kana masero ekenza anonzi Paget cells akafara kubva kukenza iri mukati memazamu kuenda kuganda renipple neareola. Aya masero chaiwo ekenza anoita kuchinja kwakasiyana-siyana paganda ravanachiremba vanogona kuona pasi pemikroskopu.

Chirwere ichi chinowanzoitika nekenza yemazamu inopinda mukati kana kuti ductal carcinoma in situ (DCIS) kune imwe nzvimbo mumazamu. Funga nezvazvo se masero ekenza achifamba kubva panzvimbo yavo yekutanga kuti atambudze nzvimbo yenyupple chaizvo.

Chirwere ichi chakapihwa zita naSir James Paget, nyanzvi yezvekurapa yeBritish yakachirondedzera kekutanga muna 1874. Kunyange zvazvo ichifungwa sechisingawanzoitika, kuziva nekurapa kwakakurumidza kunotungamira kumigumisiro yakanaka kune vanhu vakawanda.

Ndeapi Zviratidzo zvePaget's Disease Yemazamu?

Zviratidzo zvePaget's disease kazhinji zvinoonekwa zvishoma nezvishoma uye zvinogona kunyengerera zviri nyore sezvirwere zve ganda zvakajairika. Ungacherechedza kutanga zvinotaridzika seronda risingaperi kana kuti kutsamwa kwepasi risingapindure kurapwa kwakajairika.

Aya ndiwo zviratidzo zvikuru zvaunofanira kutarisa:

• Kutsvukuruka kwenguva refu, kuomarara, kana kuti kuvhara kwenipple neareola
• Kutsamwa kana kuti kupisa munzvimbo yenyupple
• Ganda rinobvaruka kana kuti rinobvisa rinotaridzika sek eczema
• Kuwedzera kwenipple kana kuti ganda reareola
• Kubuda kweropa kana kuti mvura kubva muniplle
• Kuchinja kweumbozha hwenipple kana kuti kuita concave
• Bofu kana kuti kuwanda kwetishu yemazamu

Aya zviratidzo kazhinji anokanganisa mazamu rimwe chete uye haaoneki akavandudzwa nemafuta eganda kana kurapwa kwakawanda. Musiyano mukuru nezvirwere zve ganda zvakajairika ndewokuti zviratidzo zvePaget's disease zvinoenderera mberi uye zvinogona kuipa zvishoma nezvishoma nekufamba kwenguva.

Dzimwe nguva, ungasanzwe bofu mumazamu ako kunyange kana Paget's disease iripo. Izvi zvinoitika nekuti kenza iri mukati ingave diki kana kuti iri mukati metishu yemazamu kwaoma kuona nekutambanudza chete.

Chii Chinokonzera Paget's Disease Yemazamu?

Paget's disease inoitika kana masero ekenza kubva kukenza iri mukati memazamu akafamba nemidziyo yemukaka kusvika kune nipple neareola. Chikonzero chaicho chekuti mamwe makenza anopararira nenzira iyi nepo mamwe asingadaro hachizivisike zvizere nevanachiremba.

Fungidziro inogamuchirwa zvikuru inoratidza kuti Paget cells dzinobva kuductal carcinoma in situ kana kuti kenza yemazamu inopinda mukati kune imwe nzvimbo mumazamu. Aya masero ekenza anozofamba-famba pamidziyo yemukaka kusvika asvika pamusoro penipple, kwaanoita kuchinja kwakasiyana-siyana paganda.

Imwe fungidziro inoratidza kuti Paget cells dzinogona kuitika dzoga munzvimbo yenyupple. Zvisinei, izvi hazvina kukwana sezvo zviitiko zvese zvePaget's disease zvinoitika pamwe chete neimwe mhando yekenza yemazamu mumazamu imwe chete.

Kusiyana nemamwe marudzi ekenza, Paget's disease haina kukonzera zvakananga nezvinhu zvemararamiro, zvinhu zvakapoteredza, kana kuti zvirwere. Inotaridzika kuva nzira yakasiyana yekuti mamwe makenza yemazamu anoita sei uye anopararira mukati metishu yemazamu.

Rini Unofanira Kuona Nachiremba Nezve Paget's Disease Yemazamu?

Unofanira kuona nachiremba kana ukaona kuchinja chero kupi muniplle kana kuti areola kwenguva yakareba kupfuura mavhiki mashoma. Kunyange zvazvo kuchinja kwakawanda kwenipple kune zvikonzero zvisingakuvadzi, zvakakosha kuti zvinyorwe zvakakodzera.

Rongedza nguva nekukurumidza kana ukaona chero chimwe chezviratidzo izvi zvekutyisidzira:

• Ronda renipple kana kuti kutsamwa kwepasi risingavandudzwi nekutarisira kwakapfava
• Ganda rinoumba, rinoputika, kana kuti rinobvaruka rinoramba richidzoka
• Kubuda chero kupi kubva muniplle, kunyanya kana kuri ropa
• Kuchinja kweumbozha hwenipple kana kuti kuita concave kamwe kamwe
• Kutsamwa kwenguva refu kana kuti kupisa kwasingapindure kurapwa
• Bofu kana kuti kuwanda kwetishu chero kupi mumazamu ako

Usamirira kuona kana zviratidzo zvichapera zvega, kunyanya kana zviri kukanganisa mazamu rimwe chete. Kuziva nekurapa kwakakurumidza kwePaget's disease kunovandudza zvikuru migumisiro uye sarudzo dzekurapa.

Kana wanga uchirapa zvaunofunga kuti eczema kana kuti dermatitis paniplle kwemwedzi yakati wandei pasina kuvandudzwa, nguva yakwana yekubvunza nachiremba. Vanogona kuona kana uchida kuongororwa zvakawanda kana kuti kutumirwa kunyanzvi.

Ndeapi Zvinhu Zvinowedzera Ngozi yePaget's Disease Yemazamu?

Zvinhu zvinowedzera ngozi yePaget's disease zvakafanana nezvinhu zvinowedzera ngozi yemamwe marudzi ekenza yemazamu, sezvo chirwere ichi chinowanzoitika pamwe chete nekenza iri mukati memazamu. Kunzwisisa zvinhu izvi kunogona kukubatsira kuramba uchiri kuziva nezvemazinga ako engozi.

Aya ndiwo zvinhu zvikuru zvinowedzera ngozi zvaunofanira kuziva nezvazvo:

• Zera - kazhinji chinotambudza vakadzi vane makore anopfuura 50, kunyange zvazvo chingaita chero zera ripi zvaro
• Rudzi - vakadzi vanowanzotambudzwa nechirwere ichi kupfuura varume
• Nhoroondo yemhuri yekenza yemazamu kana kuti kenza yeovari
• Nhoroondo yako yekenza yemazamu kana kuti zvirwere zvemazamu zvine ngozi yakawanda
• Kuchinja kwemajini, kunyanya BRCA1 neBRCA2
• Tishu yemazamu yakakora
• Kurapwa kwakapfuura neradiotherapy munzvimbo yechipfuva
• Kushandisa hormone replacement therapy

Kuva nezvinhu zvinowedzera ngozi chimwe kana kupfuura hazvirevi kuti uchave nePaget's disease. Vanhu vakawanda vane zvinhu zvinowedzera ngozi havambofi vaine kenza yemazamu, nepo vamwe vasina zvinhu zvinozivikanwa zvinowedzera ngozi vachinazvo. Zvinhu izvi zvinongobatsira vanachiremba kunzwisisa maitiro uye kurumbidza kuongororwa kwakakodzera.

Zvinokosha kucherechedza kuti Paget's disease inogona kuitika muvakadzi vaduku uye kunyange muvarume, kunyange zvazvo izvi zvisingawanzoitika. Chirwere ichi hachisarudzi zvichibva pazvinhu zvinowedzera ngozi chete, ndosaka kucherechedza zviratidzo kuchikosha kune munhu wese.

Ndeapi Matambudziko Anogona Kuitika ePaget's Disease Yemazamu?

Kana Paget's disease yakawanikwa nekukurumidza uye yakarapwa zvakakodzera, vanhu vakawanda vane migumisiro yakanaka. Zvisinei, sekune mamwe marudzi ekenza yemazamu, kunogona kuva nematambudziko kana chirwere ichi chikaenderera mberi pasina kurapwa.

Matambudziko makuru aunofanira kunzwisisa anosanganisira:

• Kupararira kwenza kuma lymph nodes ari pedyo
• Kupinda kwenza mukati metishu yemazamu yakadzika
• Kupararira kwenza kune dzimwe nzvimbo dzemuviri
• Kuitika kwezvimwe zvirwere mumazamu imwe chete kana kuti akasiyana
• Kutambudzwa kwenguva refu kwenzvimbo yenyupple nekuda kwemavari akavhurika
• Kuchinja kwenguva refu kweumbozha hwemazamu kana kuti chitarisiko cheniplle

Mashoko akanaka ndeawo kuti kana Paget's disease yakawanikwa nekukurumidza, kenza iri mukati kazhinji inenge ichiri mukati metishu yemazamu kana kuti yakaganhurirwa kune nzvimbo dziri pedyo. Izvi zvinoita kuti kurapwa kuve kwakanyanya kushanda uye kuderedza njodzi yematambudziko akakomba.

Vamwe vanhu vanonetseka nezvemigumisiro yemanzwiro nepfungwa yekutambura nekenza yemazamu. Aya matambudziko akajairika uye akakodzera. Nzvimbo dzakawanda dzekurapa dzinopfumisa mazano uye rubatsiro rwekupa kuti zvikubatsire kufamba nezvinhu zvemumuviri nepfungwa zvechirwere chako nekurapwa.

Paget's Disease Yemazamu Inoziviswa Sei?

Kuziva Paget's disease kunoda kusanganiswa kwekuongororwa kwemuviri, kudzidza kwemaitiro, uye kuongororwa kwetishu. Nachiremba wako anotanga nekuongorora zvakanyanya nipple nenharaunda yemazamu ako, achitsvaga kuchinja kwakasiyana-siyana kunoratidza chirwere ichi.

Maitiro ekuongorora kazhinji anosanganisira nhanho dzakati wandei. Kutanga, nachiremba wako achaita bvunzo yemuviri yemazamu uye kubvunza nezvezviratidzo zvako uye kuti wakanga uine kwenguva yakareba sei. Vachanzwa kana kuchinja kuri kukanganisa mazamu rimwe kana maviri uye kana wakamboedza kurapwa kupi zvaro.

Zvadaro, ungada kuongororwa kwemaitiro kuti uone kenza iri mukati memazamu. Mammogram kazhinji ndiyo bvunzo yekutanga yemaitiro, inoteverwa ne ultrasound yemazamu kana MRI kana zvichidiwa. Aya maitiro anobatsira kuziva chero zvirwere kana nzvimbo dzine njodzi dzisinganzwikwi panguva yekuongororwa kwemuviri.

Kuongororwa kwakakwana kunobva kubiopsy yenzvimbo yenyupple yakabatwa. Panguva iyi, nachiremba wako anobvisa sampuli diki yeganda, iyo inozooongororwa pasi pemikroskopu nenhengo inonzi pathologist. Vachatsvaga Paget cells chaiyo dzinoratidza chirwere chacho.

Kana Paget's disease yakasimbiswa, zvimwe zvibvunzo zvingadiwa kuti zione huwandu hwenza iri mukati. Izvi zvingasanganisira zvimwe zvidzidzo zvemaitiro kana kuti mamwe mabiopsy kubatsira kuronga nzira yekurapa yakakodzera kune mamiriro ako chaiwo.

Kurapa kwePaget's Disease Yemazamu Kudii?

Kurapa kwePaget's disease kunotarisa pakugadzirisa kuchinja kwenipple nekenza iri mukati. Purogiramu yako yekurapa ichagadzirirwa mamiriro ako chaiwo, kusanganisira saizi nemhando yekenza iri mukati uye kana kenza yakapararira kuma lymph nodes.

Kuoperezha kazhinji ndiyo nzira huru yekurapa. Sarudzo yakajairika yekuoperezha ndeye mastectomy, iyo inobvisa mazamu ese, nipple, neareola. Nzira iyi inoona kuti zvese Paget's disease nekenza iri mukati zvakabviswa zvizere.

Muimwe nguva, kuoperezha kunodzivirira mazamu kungave kuitika kana kenza iri mukati iri diki uye iri kure nenharaunda yenyupple. Zvisinei, nzira iyi inoda kubviswa kwenipple neareola, pamwe chete nekenza netishu dziri pedyo. Sarudzo inobva pazvinhu zvakaita saizi yekenza, nzvimbo, uye zvaunoda.

Mushure mekuoperezha, zvimwe zvekurapa zvingarumbidzwa zvichibva pazvinhu zvekensa yako. Izvi zvingasanganisira:

• Chemotherapy kubvisa chero masero ekenza asara
• Radiation therapy kuderedza njodzi yekenza kudzoka
• Hormone therapy kana kenza yako ichinzwa mahomoni
• Mishonga inorwisa kenza chaiyo yemamwe marudzi ekenza

Timu yako yekurapa ichaita basa newe kugadzira purogiramu yekurapa yakazara inogadzirisa kenza yako uchifunga nezveutano hwako hwese, zvaunoda, nezvinangwa zvako zveupenyu. Sarudzo dzekurapa dzinoitwa nguva dzose pamwe chete newe nevanachiremba vako.

Nzira Yekutarisira Zviratidzo Pamba Panguva Yekurapa?

Paunenge uri kurapwa kwePaget's disease, kune nzira dzakapfava dzekuzvichengeta pamba dzinoita kuti unzwe wakasununguka. Aya matanho ekutsigira anoshanda pamwe chete nekurapa kwako kwezvekurapa, kwete sechinoshandiswa panzvimbo payo.

Kune kutarisira kwenipple neganda, chengeta nzvimbo yakabatwa yakachena uye yakaoma uchishandisa sipo yakapfava, isina kunhuhwirira. Dzivisa kushambidza zvakasimba kana zvinhu zvinokuvadza ganda zvingaita kuti ganda rive rakaipa. Pane kudaro, nyoro nyoro nzvimbo yacho mushure mekushambidza uye dzivisa mabhuresi kana nguo dzakasimba dzisingakuvadze ganda rako.

Kutarisira kusagadzikana kwakakosha kune hutano hwako hwese. Zvinodzora marwadzo zvisingadi kurapwa zvakaita seacetaminophen kana ibuprofen zvinogona kubatsira nekusingafadzi, asi bvunza nachiremba wako kutanga kuti uve nechokwadi chekuti mishonga iyi haizokanganisi kurapwa kwako.

Rubatsiro rwemanzwiro kwakakosha sezvekutarisira kwemuviri. Funga nezvekubatanidza boka rerubatsiro revanhu vane kenza yemazamu, kana munhu kana pamhepo. Kubatana nevamwe vanonzwisisa zvamuri kutambura nazvo kunogona kupa nyaradzo uye mazano anoshanda.

Chengeta chikafu chakanaka uye kurovedza muviri kwakapfava sezvakabvumirwa netimu yako yekurapa. Aya maitiro anotsigira muviri wako wekurapa uye anogona kukubatsira kunzwa ukasimba panguva yekurapa. Yeuka kuti zororo rakakoshawo, saka teerera kumuviri wako uye usazviitisa zvakanyanya.

Ungagadzirira Sei Kune Nguva Yako Yekuona Nachiremba?

Kuagadzirira nguva yako yekuona nachiremba kunobatsira kuona kuti unowana zvakanyanya kubva pakushanya kwako uye usakanganwa ruzivo rwakakosha. Tanga nekunyora zviratidzo zvako zvese, kusanganisira kuti zvakatanga riini uye kuti zvakachinja sei nekufamba kwenguva.

Uye uunze rondedzero yakazara yemishonga yese, mavhitamini, nezvinowedzerwa zvamuri kutora. Sanganisira mishonga inorayirwa nachiremba, mishonga isingadi kurapwa, uye chero mishonga yezvinomera. Nachiremba wako anoda ruzivo urwu kunzwisisa zvinogona kukanganisa uye kuronga kutarisira kwako zvakachengeteka.

Unganidza nhoroondo yako yekurapa, kusanganisira chero matambudziko emazamu apfuura, mabiopsy, kana kuti kuongororwa kwenza. Kana uine nhengo dzemhuri dzine kenza yemazamu kana kuti kenza yeovari, nyora hukama hwavo newe nemazera avo pavakaongororwa. Ruzivo urwu rwenhoroondo yemhuri runobatsira nachiremba wako kuona zvinhu zvinowedzera ngozi.

Gadzira rondedzero yemibvunzo yaunoda kubvunza. Usanetseka nezvekuva nemibvunzo yakawanda - nachiremba wako anokutarisa uye anogamuchira.

• Ndeapi maitiro achafanirwa kuitwa kuti aongorore chirwere ichi?
• Ndeapi maitiro ekurapa anogona kuitwa?
• Ndeapi njodzi uye mabhenefiti emaitiro ese ekurapa?
• Kurapwa kuchakanganisa sei mabasa angu ezuva nezuva?
• Ndeapi masevhisi ekutsigira aripo?

Funga nezvekukoka shamwari kana nhengo yemhuri yakavimbika kune nguva yako yekuona nachiremba. Vanogona kupa rubatsiro rwemanzwiro uye kukubatsira kurangarira ruzivo rwakakosha rwakataurwa panguva yekushanya. Kuva nemunhu aripo kunokupawo mumwe munhu wekubvunza mibvunzo kana uchifunga chimwe chinhu gare gare.

Chii Chinonyanya Kukosha Nezve Paget's Disease Yemazamu?

Paget's disease yemazamu chirwere chisina kujairika asi chinorapika chekenza yemazamu chinotambudza nipple neareola. Kunyange zvazvo zviratidzo zvingave zvichitaridzika sezvirwere zve ganda zvakajairika, kuchinja kwenguva refu kusina kuvandudzwa nekutarisira kwakapfava kunoda kuongororwa nachiremba.

Kuziva nekukurumidza kunoita musiyano mukuru mumigumisiro yekurapa. Kana ukaona kuchinja chero kupi kwenipple, kuomarara, kubuda, kana kuti kutsamwa kwenguva yakareba kupfuura mavhiki mashoma, usambotya kuona nachiremba. Zvingave zvichitaridzika sedambudziko diki reganda zvingave chimwe chinhu chinoda kutarisirwa nekukurumidza.

Chinhu chinonyanya kukosha chekurangarira ndechekuti kurapwa kwakakosha kuripo, uye vanhu vakawanda vane Paget's disease vanorarama hupenyu hwazvo hwese, hwakanaka mushure mekurapwa. Kunyange kuwana chero kuongororwa kwenza kunonzwa kuchinetesa, hausi wega mu rwendo urwu.

Ramba uine hukama netimu yako yekurapa, bvunza mibvunzo kana uchida kujeka, uye usatya kutsvaka rubatsiro rwemanzwiro. Kutarisira hutano hwako hwepfungwa nemanzwiro kwakakosha sezvekugadzirisa zvinhu zvemuviri zvechirwere chako.

Mibvunzo InowanzoBvunzwa Nezve Paget's Disease Yemazamu

Mubvunzo 1: Paget's disease yemazamu inogona kuitika muvarume here?

Hungu, kunyange zvazvo zvisingawanzoitika, varume vanogona kutambura nePaget's disease yemazamu. Kenza yemazamu yevamwe pachayo haina kujairika, ichinowanikwa mu1% yezvirwere zvese zvekenza yemazamu, uye Paget's disease muvarume yakanyanya kushomeka. Kana ikaitika muvarume, zviratidzo uye nzira yekurapa zvakafanana nezvevakadzi. Varume vanofanirawo kutarisa kuchinja chero kupi kwenguva refu munzvimbo yenyupple uye kutsvaka kuongororwa nachiremba kana zvichidiwa.

Mubvunzo 2: Paget's disease yemazamu yakafanana nePaget's disease yemapfupa here?

Kwete, aya mamiriro akasiyana zvachose ane mazita akafanana. Paget's disease yemazamu rudzi rwekenza yemazamu inokanganisa nzvimbo yenyupple, nepo Paget's disease yemapfupa chirwere chinoramba chichiitika chinokanganisa kugadzirwa kwemashure uye hachina chekuita nekenza. Chirwere chemapfupa chakajairika zvikuru uye kazhinji chinotambudza vakuru vakwegura, zvichikonzera marwadzo emapfupa nekuora. Kuva nechirwere chimwe hakuwedzeri njodzi yako yechimwe.

Mubvunzo 3: Paget's disease inogona kudzivirirwa here?

Hapana nzira chaiyo yekudzivirira Paget's disease yemazamu sezvo yakabatana zvakasimba nekuitika kwenza yemazamu. Zvisinei, unogona kutevera mazano ekudzivirira kenza yemazamu akajairika senge kuchengeta uremu hwakanaka, kurovedza muviri nguva dzose, kuderedza kunwa doro, uye kudzivisa hormone replacement therapy isingakoshi. Chinonyanya kukosha, gara uchiziva nezvemazano ekutarisa kenza yemazamu uye ita bvunzo dzemazamu pachako nguva dzose kuti uone kuchinja chero kupi nekukurumidza.

Mubvunzo 4: Zvinotora nguva yakareba sei kuti zviratidzo zvePaget's disease zvibude?

Zviratidzo zvePaget's disease kazhinji zvinoonekwa zvishoma nezvishoma kwemwedzi kana kuti kunyange makore. Vanhu vakawanda vanotanga kuona zvinotaridzika sekutsamwa kwepasi reganda risingaperi kana kuti riri kuipa nekufamba kwenguva. Kuenderera mberi kwakanyanya ndechimwe chezvikonzero nei chirwere ichi chinonyengerera sek eczema kana kuti mamwe marudzi eganda pakutanga. Vamwe vanhu vangave nezviratidzo kwemwedzi yakati wandei vasati vatsvaka rubatsiro rwezvekurapa, ndosaka kuchinja kwenguva refu kwenipple kunofanira kuongororwa nachiremba nguva dzose.

Mubvunzo 5: Chii chiyero chehupenyu hurefu hwePaget's disease yemazamu?

Kuongororwa kwePaget's disease kunonyanya kubva pazvinhu zvekensa iri mukati, kunyanya kana yakapararira kuma lymph nodes kana kuti dzimwe nzvimbo dzemuviri. Kana yakawanikwa nekukurumidza uye kenza iri mukati iri mumazamu, huwandu hwehupenyu hurefu hwakanaka, zvakafanana nemamwe makenza emazamu ekutanga. Huwandu hwehupenyu hurefu hwemakore mashanu hunosvika 80-90% kune chirwere chakaganhurirwa. Nachiremba wako anogona kupa ruzivo rwakakwana zvichibva pakuongororwa kwako uye kuongororwa kwenza yako.