Pheochromocytoma

Pheochromocytoma (fee-o-kroe-moe-sy-TOE-muh) chirwere chisingaperi chinoita tumor munokukuru adrenal. Kazhinji, tumor haisi kanesa. Kana tumor isiri kanesa, inonzi benign. Une makukuru maviri e adrenal - imwe iri pamusoro peitsvo imwe neimwe. Makukuru e adrenal anoita mahomoni anobatsira kudzora maitiro akakosha mumuviri, akadai sekumanikidza kwe ropa. Kazhinji, pheochromocytoma inoumbwa mukukuru rimwe chete re adrenal. Asi matumor anogona kukura mumakukuru ese e adrenal. Ne pheochromocytoma, tumor inoburitsa mahomoni anogona kukonzera zviratidzo zvakasiyana-siyana. Zvinosanganisira kumanikidza kwepamusoro kweropa, kurwadziwa kwemusoro, kupererwa nemvura uye zviratidzo zvekushamisika. Kana pheochromocytoma isina kurapwa, kukuvara kwakakomba kana kunotyisa kune mamwe masisitimu emuviri kunogona kuitika. Kuvhiya kubvisa pheochromocytoma kazhinji kunodzosera kumanikidza kwepamusoro kweropa kune huwandu hune hutano.

Pheochromocytoma inowanzoita zviratidzo zvinotevera: Kuwedzera kweropa.Kutadza musoro.Kuwedzera kwekuita zvemukati.Kurova kwemoyo nekukurumidza. Vamwe vanhu vane pheochromocytomas vane zviratidzo zvakadai se: Kuzunguza kwetsoka.Ganda rinotendeuka ruvara rwakajeka, rinonziwo pallor.Kushomeka kwemhepo.Zviratidzo zvekutambudzika kwepanic, izvo zvinogona kusanganisira kutya kukuru kamwe kamwe.Kunetseka kana kunzwa kwekufamba kwakaipa.Matambudziko ekutarisa.Kunetsekana.Kurasikirwa nehuremu. Vamwe vanhu vane pheochromocytomas havaone zviratidzo. Havazivi kuti vane gomba kusvika bvunzo yekufananidzira ikawana. Kazhinji, zviratidzo zvepheochromocytoma zvinouya uye zvinoenda. Kana zvichizoitika kamwe kamwe uye zvichienderera mberi, zvinozivikanwa sekuita kana kurwiswa. Aya maitiro angave kana kusaitika trigger inogona kuwanikwa. Zvimwe zviitiko kana mamiriro ezvinhu zvinogona kutungamira pakurwara, zvakadai se: Kushanda kwemuviri kwakaoma.Kunetseka kana kushushikana.Kuchinja kwemamiriro emuviri, sekubendera, kana kuenda kubva pakugara kana kurara kusvika kumira.Kubereka nekuzvara.Kuopereta uye mushonga unoita kuti uve munhu ari kurara panguva yekuopereta, unonzi anesthetic. Zvokudya zvine tyramine yakawanda, chinhu chinoita kuti ropa riwedzere, zvinogona kutungamirawo pakurwara. Tyramine inowanzova muzvokudya zvakachendwa, zvakakwegura, zvakachengetedzwa, zvakasvibiswa, zvakakura kana zvakashata. Aya mazai anosanganisira: Mamwe chizi.Mamwe biera nemavhinzi.Soybeans kana zvigadzirwa zvakagadzirwa ne soy.Chocolate.Nyama yakaoma kana yakasvuta. Mishonga nemidziyo inogona kutungamira pakurwara inosanganisira: Mishonga yekudzikisa manzwiro inonzi tricyclic antidepressants. Mimwe mienzaniso yetricyclic antidepressants ndiyo amitriptyline ne desipramine (Norpramin).Mishonga yekudzikisa manzwiro inonzi monoamine oxidase inhibitors (MAOIs), senge phenelzine (Nardil), tranylcypromine (Parnate) ne isocarboxazid (Marplan). Njodzi yekurwara yakakwirira kana aya mishonga ichitorwa nezvokudya kana zvinwiwa zvine tyramine yakawanda.Zvinokurudzira senge caffeine, amphetamines kana cocaine. Kuwedzera kweropa chimwe chezviratidzo zvikuru zvepheochromocytoma. Asi vanhu vazhinji vane kuwedzera kweropa havafaniri kuva nehomba ye adrenal. Taura nachiremba wako kana chimwe chezvinhu izvi zvichikuitikira iwe: Zviratidzo zvechiratidzo zvakabatana ne pheochromocytoma, zvakadai sekutambudzika musoro, kuita zvemukati uye kurova kwemoyo nekukurumidza, kwakasimba.Kunetseka kudzora kuwedzera kweropa nekurapa kwako ikozvino.Kuwedzera kweropa kunotanga usati wazara makore makumi maviri.Kuwedzera kukuru kwenguva refu mukuwedzera kweropa.Nhoroondo yemhuri yepheochromocytoma.Nhoroondo yemhuri yemamiriro ezvinhu ane hukama. Izvi zvinosanganisira multiple endocrine neoplasia, rudzi 2 (MEN 2), von Hippel-Lindau chirwere, inherited paraganglioma syndromes ne neurofibromatosis 1.

KBP yakakwira imwe yezviratidzo zvikuru zve pheochromocytoma. Asi vanhu vakawanda vane BP yakakwira havave nekenza ye adrenal. Taura nachiremba wako kana chimwe chezvinhu izvi zvichikuitikira: Zvikamu zve zviratidzo zvine chekuita ne pheochromocytoma, sekusuruvara kwemusoro, kupererwa neperspiration uye kurova kwemoyo nekukurumidza, kwakasimba. Dambudziko rekudzora BP yakakwira nerapiro rauri kushandisa iye zvino. BP yakakwira inotanga usati wasvika makore makumi maviri. Kuwedzera kukuru kwenguva nenguva muBP. Nhoroondo yemhuri ye pheochromocytoma. Nhoroondo yemhuri yemamiriro ezvinhu ane hukama hwemajini. Izvi zvinosanganisira multiple endocrine neoplasia, rudzi 2 (MEN 2), von Hippel-Lindau chirwere, inherited paraganglioma syndromes uye neurofibromatosis 1.

Vatsvakurudzi havazivi chaizvoizvo chinokonzera pheochromocytoma. Utachiona hunoonekwa muma cell anonzi chromaffin cells. Aya ma cell ari pakati pe adrenal gland. Anoburitsa mamwe mahomoni, kunyanya adrenaline nenoradrenaline. Aya mahomoni anobatsira kudzora mabasa akawanda emuviri, akadai sekukurumidza kwemoyo, kumanikidza kweropa neshuga yeropa. Adrenaline nenoradrenaline zvinokonzera kupindura kwekuita zvekurwa kana kutiza kwemuviri. Iyo kupindura kunoitika kana muviri uchifunga kuti pane ngozi. Mahomoni anokonzera kuti kumanikidza kweropa kukwire uye moyo urove nekukurumidza. Anogadzirirawo mamwe masisitimu emuviri kuitira kuti ugone kupindura nekukurumidza. Pheochromocytoma inokonzera kuti mamwe ema hormones aya abudiswe. Uye inokonzera kuti abudiswe kana usinga siyi munzvimbo ine ngozi. Mazhinji ema chromaffin cells ari mu adrenal glands. Asi mapoka madiki aya ma cell ariwo mumoyo, musoro, mutsipa, nebladder, nzvimbo yemudumbu uye pamusoro pe spine. Chromaffin cell tumors dziri kunze kwe adrenal glands anonzi paragangliomas. Anogona kukonzera zvimwe chete zvinoita pheochromocytoma mumuviri.

Vanhu vane MEN 2B vane zvironda zvemitsipa muhuro, mukanwa, maziso nemuura. Vangavewo nezvironda pachikamu che adrenal gland, chinonzi pheochromocytoma, uye kenza ye medullary thyroid. Zera remunhu nezvimwe zvirwere zvinogona kuwedzera njodzi yekuve ne pheochromocytoma. Kazhinji pheochromocytomas inowanikwa muvanhu vane makore ari pakati pemakore makumi maviri nemakumi mashanu. Asi chironda chinogona kuumbwa pazera ripi neripi. Vanhu vane zvimwe zvirwere zvisingawanzoitika vane njodzi yakakwira yekuve ne pheochromocytomas. Zvironda zvinogona kuva zvakanaka, zvinoreva kuti haisi kenza. Kana zvinogona kuva zvakaipa, zvinoreva kuti kenza. Kazhinji, zvironda zvakanaka zvine chekuita nezvirwere izvi zvinoumbwa mune ese ari maviri adrenal glands. Zvirwere zvine chekuita ne pheochromocytoma zvinosanganisira:

• Multiple endocrine neoplasia, rudzi 2 (MEN 2). Iyi mamiriro anogona kukonzera zvironda muzvikamu zvakawanda zvehurongwa hwekuita mahomoni emuviri, rinonzi endocrine system. Kune marudzi maviri eMEN 2 - rudzi 2A ne rudzi 2B. Ese ari maviri anogona kusanganisira pheochromocytomas. Zvimwe zvironda zvine chekuita neaya mamiriro zvinogona kuoneka mune dzimwe nhengo dzemuviri. Izvi zvinosanganisira thyroid, parathyroid glands, miromo, mukanwa uye ura.
• Von Hippel-Lindau chirwere. Iyi mamiriro anogona kukonzera zvironda muzvikamu zvakawanda zvemuviri. Nzvimbo dzinogona kusanganisira uropi ne spinal cord, endocrine system, pancreas neitsvo.
• Neurofibromatosis 1. Iyi mamiriro inokonzera zvironda paganda rinonzi neurofibromas. Inogona zvakare kukonzera zvironda zvemitsipa kumashure kwemaziso anobatanidza neuropi, rinonzi optic nerve.
• Hereditary paraganglioma syndromes. Aya mamiriro anopfuudzwa mumhuri. Anogona kukonzera pheochromocytomas kana paragangliomas.

• Kurwara kwemoyo.
• Kutambanudzwa kwetsinga dzemagetsi (stroke).
• Kukundikana kweitsvo.
• Kurasikirwa nekuona.

Zvisingawanzoitika, pheochromocytoma inogona kunge iri kenza, uye masero ekenza anopararira kune dzimwe nzvimbo dzemuviri. Masero ekenza anobva ku pheochromocytoma kana paraganglioma kazhinji anofamba kuenda kune lymph system, mapfupa, chiropa kana mapapu.

Kuti uone kana une pheochromocytoma, nyanzvi yako yehutano inogona kukupa bvunzo dzakasiyana-siyana.

Bvunzo idzi dzinoyera mazinga ehormone adrenaline ne noradrenaline, nezvinhu zvinogona kubva kuhormone idzodzo zvinonzi metanephrines.mazinga akakwirira emetanephrines akajairika kana munhu ane pheochromocytoma.mazinga eMetanephrine haana kukwirira kana munhu ane zviratidzo zvinokonzerwa nechimwe chinhu kunze kwe pheochromocytoma.

• Bvunzo yeropa. Nyanzvi yehutano inotora sampuli yeropa kuti iongororwe murabhoritari.

Pamusoro pemhando mbiri dzebvunzo, bvunza nyanzvi yako yehutano kana uchifanira kuita chero chinhu kuti ugadzirire.Semuenzaniso, unogona kukumbirwa kusadya kwechinguva usati waita bvunzo.Izvi zvinonzi kufunga.Kana kuti unogona kukumbirwa kurega kutora mushonga chaiwo.Usarega kutora mushonga kunze kwekunge nhengo yemhuri yako yehutano ikakuudza uye ikakupa mirairo.

Kana mhinduro dzebvunzo yerabhoroti dzikaona zviratidzo zvepheochromocytoma, bvunzo dzekuona mifananidzo dzinodikanwa.Nyanzvi yako yehutano inogona kukupa imwe kana dzakawanda dzebvunzo idzi kuti uone kana une ganda.Bvunzo idzi dzinogona kusanganisira:

• CT scan, inosanganisa akatevedzana mafoto e-X-ray akatorwa kubva pakona dzakasiyana-siyana dziri pamuviri wako.
• MRI, inoshandisa ma radio wave ne magnetic field kuti uite mifananidzo yakajeka.
• M-iodobenzylguanidine (MIBG) imaging, scan inogona kuona huwandu hudiki hwe compound yeradioactive yakapinzwa.Compound inotorwa ne pheochromocytomas.
• Positron emission tomography (PET), scan inogona kuonawo ma compound eradioactive anotora ganda.

Ganda riri mu adrenal gland rinogona kuwanikwa panguva yekuongorora mifananidzo yakaitwa nezvikonzero zvimwe.Kana izvozvo zvikaitika, vanachiremba vanowanzokupa bvunzo dzakawanda kuti vaone kana ganda rinoda kurapwa.

Nyanzvi yako yehutano inogona kukurudzira bvunzo dzemajini kuti uone kana pheochromocytoma yakabatana nechirwere chemajini.Ruoko rwezvinhu zvinogona kuva zvemajini zvinogona kukosha nezvikonzero zvakawanda:

• Zvimwe zvirwere zvemajini zvinogona kukonzera matambudziko akawanda ehutano.Saka, mhinduro dzebvunzo dzinogona kuratidza kudikanwa kwekuongorora mamwe mamiriro ehutano.
• Zvimwe zvirwere zvemajini zvine mukana mukuru wekuitika zvakare kana kuva cancer.Saka, mhinduro dzebvunzo dzako dzinogona kukanganisa sarudzo dzekurapa kana marongero ekureba ekutevera hutano hwako.
• Mhinduro kubva kubvunzo dzinogona kuratidza kuti nhengo dzemhuri dzakasiyana dzinofanira kuongororwa kuti vaone kana vane pheochromocytoma kana zvirwere zvakabatana nazvo.

Genetic counseling inogona kukubatsira kunzwisisa mhinduro dzebvunzo dzako dzemajini.Inogonawo kubatsira mhuri yako kutarisira chero matambudziko ehutano hwepfungwa akabatana nekushushikana kwekuongororwa kwemajini.