Scleroderma

'Scleroderma (sklair-oh-DUR-muh), inozivikanwawo se systemic sclerosis, boka remahoshoma asingawanzoitika anobatanidza kuoma nekukombamira kweganda. Scleroderma inogona zvakare kukonzera matambudziko mutsinga dzeropa, nhengo dzemukati neura hwemudumbu.\n\nScleroderma kazhinji inoratidzirwa seyakaderera kana yakapararira, izvo zvinoreva chete huwandu hwekubatanidzwa kweganda. Marudzi ese maviri anogona kubatanidza chero chimwe chezviratidzo zvevascular kana nhengo dziri chikamu chechirwere ichi. Localized scleroderma, inozivikanwawo se morphea, inokanganisa ganda chete.\n\nKunyangwe kusina mushonga we scleroderma, kurapwa kunogona kuunza nyore zviratidzo, kunononotsa kufambira mberi uye kuvandudza hupenyu.'

Zviratidzo zveScleroderma zvinosiyana kubva kune munhu kuenda kune mumwe munhu, zvichienderana nezvikamu zvemuviri zvakabatwa. Avo vane scleroderma vanenge vose vanosangana nekuoma nekukombamira kwe ganda. Zvikamu zvemuviri zvinotanga kubatwa kazhinji ndemunwe, maoko, tsoka nechemberi. Kune vamwe vanhu, kuwanda kwepasi peganda kunogona kusanganisirawo maoko, maoko epamusoro, chipfuva, mudumbu, makumbo epazasi nemabvi. Zviratidzo zvepakutanga zvinogona kusanganisira kuzvimba nekukwenya. Ruvara rweganda rakabatwa runogona kuva rakachena kana rakaita rima, uye ganda rinogona kuoneka rakapenya nekuda kwekuoma. Vamwe vanhu vanewo mavara maduku matsvuku, anonzi telangiectasia, paruoko nepa chiso. Calcium deposits inogona kuumbwa pasi peganda, kunyanya pamunwe, zvichikonzera mahombekombe anogona kuonekwa pane X-rays. Raynaud's phenomenon inowanzoitika mu scleroderma. Inoitika nekuda kwekuita kwakasimba kwemisodzi midiki yeropa munwe nemunwe semhinduro kune tembiricha inotonhora kana kunetseka kwemanzwiro. Kana izvi zvikaitika, minwe inogona kunzwa marwadzo kana kushaya simba uye kuchinja kuva chena, bhuruu, grey kana tsvuku. Raynaud's phenomenon inogonawo kuitika kune vanhu vasina scleroderma. Scleroderma inogona kukanganisa chero chikamu che digestive system, kubva ku esophagus kuenda ku rectum. Zvichienderana nezvikamu zve digestive system zvakabatwa, zviratidzo zvinogona kusanganisira: - Heartburn. - Kunetseka kukura. - Kuwomba. - Manyoka. - Kuvimbiswa. - Fecal incontinence. Kana scleroderma ikakanganisa mwoyo kana mapapu, inogona kukonzera kushaya mweya, kudzikira kwekuita zvemitambo uye kuzvinzwa musoro. Scleroderma inogona kukonzera kuita mavara mumapapu anogona kukonzera kuwedzera kushaya mweya nekufamba kwenguva. Kune mishonga inogona kubatsira kudzikisira kufambira mberi kwekuvadza kwemapapu aya. Kana scleroderma ikakanganisa mwoyo, kurova kwemoyo kunogona kuva kusina kururama. Kukundikana kwemoyo kunogonawo kuitika kune vamwe vanhu.

Scleroderma inoitika kana muviri wagadzira collagen yakawanda uye inoungana munyama yemuviri. Collagen rudzi rwemaproteni ane shinda unoita tishu dzinobatanidza muviri, kusanganisira ganda.

Nyanzvi hadzina chokwadi chekuti chii chinokonzera iyi nzira kutanga, asi masimba emuviri anoita kunge ane basa. Zvichida, scleroderma inokonzerwa nekusanganiswa kwezvinhu, kusanganisira matambudziko emasimba emuviri, genetics uye zvinokonzera zvakatipoteredza.

Munhu wese anogona kuwana scleroderma, asi inowanzoitika kune vanhu vakapihwa vakadzi panguva yekuzvarwa. Vanhu vanowanzo kuwana scleroderma pakati pemakore makumi matatu nemakumi mashanu. Vanhu vatema kazhinji vane kutanga kare uye vane mukana mukuru wekuve nekutambudzika kwepanyama uye chirwere chemapapu.

Zvimwe zvinhu zvakawanda zvakasanganiswa zvinoita sekunge zvinokanganisa njodzi yekuve ne scleroderma:

• Genetics. Vanhu vane shanduko dzemajini vanoita sekunge vane mukana mukuru wekuvandudza scleroderma. Izvi zvinogona kutsanangura kuti sei scleroderma inoita sekufamba mumhuri muhuwandu hudiki hwevanhu uye nei mamwe marudzi e scleroderma ari akajairika kune vanhu vari mune dzimwe nharaunda nedzinza.
• Zvinokonzera zvakatipoteredza. Kutsvagisa kunoratidza kuti mune vamwe vanhu, zviratidzo zve scleroderma zvinogona kukonzerwa nekuiswa kune mamwe mavhairasi, mishonga kana zvinodhaka. Kuwanikwa kwakawanda, sekushanda, kune zvinhu zvine ngozi kana makemikari zvinogona zvakare kuwedzera njodzi ye scleroderma. Chinokonzera chakatipoteredza hachizivikanwi kune vanhu vazhinji.
• Zvirwere zve immune system. Scleroderma inofungidzirwa kuva chirwere che autoimmune. Izvi zvinoreva kuti chinoitika zvikamu nekuti immune system yemuviri inotanga kurwisa connective tissues. Vanhu vane scleroderma vanogonawo kuva nezviratidzo zvechirwere chimwe cheautoimmune se rheumatoid arthritis, lupus kana Sjogren syndrome.

Zvinetso zveScleroderma zvinosvika kubva pazvishoma kusvika pakukomba uye zvinogona kukanganisa zvinotevera:

• Minwe yeminwe. Mu systemic sclerosis, Raynaud's phenomenon inogona kuva yakakomba zvokuti ropa rinodzika rinotambudza tishu pamunwe wemunwe, zvichikonzera maburi kana maronda eganda. Kune vamwe vanhu, tishu pamunwe wemunwe inogona kufa.
• Mwoyo. Kuita mavara etishu yemwoyo kunowedzera njodzi yekusagadzikana kwemwoyo nekutadza kwemwoyo. Scleroderma inogona zvakare kukonzera kuzvimba kwechikwama chinopoteredza mwoyo.
• Sisitimu yekugaya. Zvinetso zveScleroderma zvekugaya zvinogona kusanganisira heartburn uye kuoma kukurya. Scleroderma inogona zvakare kukonzera kurwadziwa kwemimba, kuzvimba, kuvimbiswa kana manyoka. Vamwe vanhu vane scleroderma vanogonawo kuva nezvinetso zvekugamuchira zvinovaka muviri nekuda kwekuwanda kwemabhakitiriya mumatumbo.
• Joints. Ganda pamusoro pejoints rinogona kuoma zvokuti rinodzivisa kufamba, kunyanya mumaoko.

Nekuda kwokuti scleroderma inogona kutora zvimiro zvakawanda uye kukanganisa nzvimbo dzakawanda dzomuviri, zvinogona kuoma kuiziva.

Mushure mekuongororwa kwemuviri kwakakwana, nyanzvi yako yehutano inogona kukurudzira bvunzo yeropa kuti uone kana paine maantibody akawanda akagadzirwa nehurongwa hwemudziviriri wemumuviri.

Nyanzvi yako yehutano inogonawo kukurudzira bvunzo dzakasiyana dzeropa, mifananidzo kana bvunzo dzebasa retsvina. Bvunzo idzi dzinogona kubatsira kuona kana hurongwa hwako hwekugaya, mwoyo, mapapu kana itsvo zvakakanganiswa.