Necrosis Ye Epidermal Yakakonzera Chepfu

TEN inokonzeresa maronda akawanda ane mahwanda, ganda rinobvaruka.

Toxic epidermal necrolysis (TEN) chirwere chisingawanzoitika, chinotyisa ganda, kazhinji chinoitika nekuda kwemishonga. Iyo ndiyo fomu yakakomba yeStevens-Johnson syndrome (SJS). Munhu ane SJS, TEN inoonekwa kana kupfuura 30% yepasi peganda rava kukanganiswa uye zvinhu zvinonamira mumuviri (mucous membranes) zvakakuvadzwa zvakanyanya.

TEN chirwere chinotyisa chinokanganisa vanhu vezera rose. TEN kazhinji inorapwa muchipatara. Apo ganda richirapa, kutarisirwa kunosanganisira kudzora marwadzo, kutarisira maronda uye kuve nechokwadi chekuti uri kunwa mvura yakakwana. Kurapa kunogona kutora mavhiki kusvika kumwedzi.

Kana mamiriro ako akaitika nemushonga, uchafanirwa kudzivisa mushonga iwoyo uye mimwe mishonga yakafanana nayo nekusingaperi.

Zviratidzo nezviratidzo zve toxic epidermal necrolysis zvinosanganisira: Kurwadziwa kwepande rese muviri Kupararira kwemavara epasi peganda kunopfukidza kupfuura 30% yemuviri Maronda nemapazi makuru eganda rinobvaruka Zvikwambo, kuzvimba nekukora pamusoro pemafuta emumuviri, kusanganisira mukanwa, maziso nevhunjini Kurapwa kwekukurumidza ndicho chinhu chikuru kune vanhu vane Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN). Kana uine zviratidzo, tsvaga rubatsiro rwekurapa nekukurumidza. Ungada kutarisirwa nachiremba we ganda (dermatologist) nevamwe nyanzvi muchipatara.

Kurapwa kwekukurumidza kunokosha kune vanhu vane Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN). Kana uine zviratidzo, tsvaga rubatsiro rwekurapa nekukurumidza. Ungada kutarisirwa nachiremba we ganda (dermatologist) nevamwe nyanzvi muchipatara.

SJS/TEN kazhinji inokonzerwa nechirwere che ganda nekuda kwemishonga. Zviratidzo zvinogona kutanga kuoneka mushure memavhiki mashanu kusvika mana watanga kutora mushonga mutsva.

Mishonga inonyanya kukonzera SJS/TEN inosanganisira mishonga inorwisa mabhakitiriya, mishonga yekurapa chirwere chekuvhiringika kwepfungwa, mishonga ye sulfa uye allopurinol (Aloprim, Zyloprim).

Zvinhu zvinoita kuti uve panjodzi yakakura yeSJS/TEN zvinosanganisira:

• Kuvira kweHIV. Pakati pevanhu vane HIV, huwandu hweSJS/TEN hunenge hwakakura ka100 kupfuura pakati pevanhu vose.
• Sisitimu yekudzivirira muviri yakasimba. Sisitimu yekudzivirira muviri inogona kukanganiswa nekusimudzirwa kwechikamu chemukati, HIV/AIDS uye zvirwere zvinorwisa muviri.
• Kenza. Vanhu vane kenza, kunyanya kenza yeropa (hematologic malignancies), vari panjodzi yakakura yeSJS/TEN.
• Nhoroondo yeSJS/TEN. Kana wakamborwara nechirwere ichi chinokonzerwa nemishonga, uri panjodzi yekuzorwara zvakare kana ukashandisa mushonga iwoyo zvakare.
• Nhoroondo yemhuri yeSJS/TEN. Kana hama yepedyo, semubereki kana munun'una, akamborwara neSJS/TEN, unogona kuva panjodzi yakakura yekuzorwarawo.
• Zvinhu zvemagwenya. Kuva nemamwe magwenya kunokukonzera panjodzi yakakura yeSJS/TEN, kunyanya kana uri kutora mishonga yekurwisa kurwadziwa, gout kana chirwere chepfungwa.

Vanhu vane ngozi yakanyanya yematambudziko eTEN ndivo vakuru vemakore anopfuura makumi manomwe nemashanu uye avo vane chirwere chechiropa kana kenza inopararira (metastatic). Matambudziko eTEN anosanganisira:

• Kuvira kweropa (sepsis). Sepsis inoitika kana mabhakitiriya kubva pakuvira apinda muropa rako wozopararira mumuviri wako wese. Sepsis chirwere chinokurumidza kuitika, chinotyisa chinogona kukonzera kukuvara kwemwoyo nekutadza kwezvikamu zvemuviri.
• Kunetseka kwemapapu. Izvi zvinogona kukonzera kukosora, kuoma kufema uye, nechirwere chakakomba, kutadza kwekufema kwenguva pfupi.
• Kuona kusina kunaka. TEN inogona kukonzera matambudziko emaziso, akadai sekuoma kwemaziso, eyelashes dzakakora, kuora kwekornea uye, zvisingawanzoitika, kurasikirwa nekuona.
• Kukuvadzwa kwepamuviri kwenguva refu. Mushure mekupora kubva kuTEN, ganda rako rinogona kuva nehutu, mavara uye kusviba. Matambudziko eganda anogara kwenguva refu anogona kukonzera bvudzi rako kudonha, uye misumari yeminwe nemaoko ako inogona kusakurira zvakanaka.
• Maronda emuviri wemukadzi. Mukadzi, TEN inogona kukonzera maronda munyama inofukidza nhengo dzemukadzi, zvichikonzera kurwadziwa kana, kana ikasarapirwa, kuvhara kwemukadzi.
• Kusuwa kwepfungwa. Iyi mamiriro ezvinhu inokonzera kunetseka uye inogona kuva nemigumisiro yakareba yepfungwa.

Kuti udzivise chimwe chiitiko cheTEN, ziva kana chakakonzerwa nemushonga. Kana zvakadaro, usambofa wakatora mushonga iwoyo kana chimwe chinhu chakafanana zvakare. Kudzokazve kungave kwakaipa uye kunotyisidzira hupenyu. Uyewo taurira vanachiremba vehutano vekare nezve nhoroondo yako yeTEN, uye pfeka bhureki rechiratidzo chekurapa kana cheni ine ruzivo nezve mamiriro ako. Kana kuti tenga pasipoti yeallergy.

TEN inozivoma kana vanhu vane SJS vakawana chirwere chakakomba chinokanganisa kupfuura 30% yemuviri.