Triple X Syndrome

Triple X syndrome, ino inonziwo trisomy X kana 47,XXX, chirwere chemagene chinotapura vakadzi vanenge 1 pavakadzi 1,000. Vakadzi vanowanzova nema chromosome maviri e-X mune ese masero — chromosome rimwe re-X kubva kuna mubereki mumwe nemumwe. MuTriple X syndrome, musikana ane ma chromosome matatu e-X.

Vasikana vakawanda nevakadzi vane Triple X syndrome havaoni zviratidzo kana kuti vane zviratidzo zvishoma. Kune vamwe, zviratidzo zvinogona kuoneka zvakajeka — zvichiita kuti pave nekunetseka kukura uye kusakwanisa kudzidza. Kuita seizure uye matambudziko etsinga kunoitika kune vasikana nevakadzi vashoma vane Triple X syndrome.

Kurapa kweTriple X syndrome kunoenderana nezviratidzo, kana zviripo, uye huwandu hwazvo.

Zviratidzo nezvirwere zvinogona kusiyana zvikuru pakati pevasikana nevakadzi vane triple X syndrome. Vakawanda havaoni zvinoita sekunge zvine matambudziko kana kuti vane zviratidzo zvishoma.

Kuva kureba kupfuura avhareji ndicho chiratidzo chinonyanya kuoneka chemuviri. Vakadzi vakawanda vane triple X syndrome vane kukura kwemukati kwakajairwa uye vane mukana wekuva nepamuviri. Vamwe vasikana nevakadzi vane triple X syndrome vane hungwaru hunowanzoitika, asi zvichida zvishoma kana zvichienzaniswa nehama. Vamwe vangave vane zvikonzero zvepfungwa uye dzimwe nguva vangave nezvinetso zvemaitiro.

Dzimwe nguva, zviratidzo zvikuru zvinogona kuitika, izvo zvinosiyana pakati pevanhu. Aya maratidzo nezviratidzo zvinogona kuoneka se:

• Kusakurumidza kukura kweutaurirano neunyanzvi rwekutaura, pamwe neunyanzvi hwemotokari, sekugara pasi kufamba
• Zvinetso zvechikoro, sekunetsa nekuverenga, kunzwisisa kana masvomhu
• Zvinetso zvemaitiro, sekusava nepfungwa/hyperactivity disorder (ADHD) kana zviratidzo zve autism spectrum disorder
• Zvinetso zvepfungwa, sekushushikana uye kuora mwoyo
• Zvinetso neunyanzvi hwemotokari hwakanaka uye hukuru, ndangariro, kutonga uye kuita kwemashoko

Dzimwe nguva vakadzi vane triple X syndrome vane aya maratidzo nezviratidzo:

• Makwinya akamira eganda anovhara makona mukati memaziso (epicanthal folds)
• Maziso akaparadzana
• Minwe yakakombama
• Makumbo akati sandara
• Bvudzi repfupa rine chimiro chakakombama mukati
• Simba resimbi rakasimba (hypotonia)
• Kuita zvekuvhiringidzika
• Zvinetso neitsvo
• Ovaries dzisingashande zvakanaka pazera duku (premature ovarian failure)

Kana uine hanya nezviratidzo zvipi zvacho kana zvirwere, gara wakaita appointment kuti utaure nachiremba wemhuri yako kana chiremba wevana, avo vanogona kukubatsira kuziva chikonzero uye kukurudzira matanho akakodzera.

Kunyangwe syndrome ye-triple X iri yemagwenga, kazhinji haina kuwanikwa kubva kuvabereki—inokonzerwa nechakaipa chemagwenga chakaitika kamwe kamwe.

Kazhinji, vanhu vane makromozomu makumi mana nemitanhatu mune imwe neimwe cell, akarongeka mumapeya makumi maviri nematatu, kusanganisira makromozomu maviri ekubereka. Imwe seti yemakromozomu inobva kuna amai uye imwe seti inobva kuna baba. Aya makromozomu ane majini, anokwanisa mirairo inotsanangura zvinhu zvose kubva pakureba kusvika kune ruvara rwemaziso.

Peji yemakromozomu ekubereka—XX kana XY—inotsanangura pabonde remwana. Amai vanogona kupa mwana kromozomu ye-X chete, asi baba vanogona kupasa kromozomu ye-X kana Y:

• Kana mwana akagamuchira kromozomu ye-X kubva kuna baba, peji ye-XX inoita kuti mwana ave musikana maererano nemagwenga.
• Kana mwana akagamuchira kromozomu ye-Y kubva kuna baba, peji ye-XY zvinoreva kuti mwana ndiye murume maererano nemagwenga.

Vakadzi vane syndrome ye-triple X vane kromozomu ye-X yechitatu kubva pakanganiso yekaparadzaniswa kwema cell. Iyi kanganiso inogona kuitika usati wabata pamuviri kana pakutanga kwekusimukira kwemwana, zvichiguma neimwe yemafomu aya e-triple X syndrome:

• Kusaparadzana. Muzviitiko zvizhinji, kana cell yezai raamai kana cell yesperm yababa inoparadzana zvisina kunaka, zvichiguma nekromozomu ye-X yakawedzerwa mumwana. Iyi kanganiso inonzi kusaparadzana, uye ma cell ose emuviri wemwana achava nekromozomu ye-X yakawedzerwa.
• Mosaic. Dzimwe nguva, kromozomu yakawedzerwa inokonzerwa nekukanganisa kwekuparadzana kwema cell kunokonzerwa nechiitiko chakaitika kamwe kamwe pakutanga kwekusimukira kwemwana. Kana zvakadaro, mwana ane fomu ye-mosaic ye-triple X syndrome, uye mamwe ma cell chete ane kromozomu ye-X yakawedzerwa. Vakadzi vane fomu ye-mosaic vangave nezviratidzo zvisinganzwisisiki.

Syndrome ye-triple X inonziwo 47,XXX syndrome nekuti kromozomu ye-X yakawedzerwa inoguma nemakromozomu makumi mana nemanomwe mune imwe neimwe cell panzvimbo yemakumi mana nemitanhatu akajairika.

Kunyangwe vakadzi vamwe vangave vasina zviratidzo kana kuti vane zviratidzo zvishoma zvine chekuita neTriple X syndrome, vamwe vanosangana nematambudziko ekukura, epfungwa neehutsika anogona kukonzera matambudziko akawanda, anosanganisira:

• Matambudziko ekubasa, kuchikoro, nemagariro evanhu nezvehukama
• Kuora mwoyo
• Kuda rubatsiro rwakawedzerwa kana kutsigirwa pakudzidza, mabasa ezuva nezuva, kuchikoro kana kubasa

Vanaamai vakawanda nevakadzi vane triple X syndrome vane hutano uye havaoneki zviratidzo zvechirwere ichi, vanogona kuramba vasina kuongororwa kweupenyu hwavo hwese, kana kuti chirwere ichi chingawanikwa pakuongorora matambudziko mamwe. Triple X syndrome inogona kuwanikwawo pakuongororwa kwepamuviri kuti zvirwere zvimwe zvemajini zvizive. Panguva yekuzvitakura, sampuli yeropa raamai inogona kuongororwa kuti ione DNA yemwana. Kana bvunzo ikaratidza njodzi yakawedzera ye triple X syndrome, sampuli yemvura kana tishu kubva mukati mechibereko inogona kuunganidzwa. Kuongororwa kwemajini emvura kana tishu kucharatidza kana paine chromosome yeX yakawedzerwa, yechitatu. Kana triple X syndrome ikakurukurwa mushure mekuberekwa zvichienderana nezviratidzo, inogona kusimbiswa nekuongororwa kwemajini. Kuwedzera pakuongororwa kwemajini, mazano emajini anogona kukubatsira kuwana ruzivo rwakakwana nezve triple X syndrome.