Chii Chinonzi Undifferentiated Pleomorphic Sarcoma? Zviratidzo, Zvinokonzera, & Kurapa

Undifferentiated pleomorphic sarcoma (UPS), rudzi rwekenza inowanikwa munyama yakapfava mumuviri, kazhinji mumaoko, makumbo, kana mudumbu. Zita rayo rinobva pakuti masero ayo anotaridzika zvakasiyana-siyana pasi pemikroskopu, asingafaniri chero rudzi rwe tishu.

UPS inonzi kenza isingawanzoitika, ichikanganisa vanhu 1 pavagumi zviuru gore rega rega. Kunyange zvazvo kuziva izvi kungaita kuti unzwe uchitya, kunzwisisa zviri kuitika kwauri kunogona kukubatsira kuti ugadzirire zviri nani uye uve nechivimbo mu rwendo rwe kurapwa rwuri pamberi.

Chii chinonzi undifferentiated pleomorphic sarcoma?

Undifferentiated pleomorphic sarcoma ikensa inokura munyama yakapfava senge tsandanyama, mafuta, ropa, kana tishu dzinobatanidza. Shoko rokuti "undifferentiated" rinoreva kuti masero ekensa haataridziki serudzi rwakati rwe sero remunhu, zvichiita kuti zviome kuziva rudzi rwayo.

Shoko rokuti "Pleomorphic" rinotsanangura kuti masero aya ekensa ane maumbirwo akasiyana-siyana nehukuru kana akaonekwa pasi pemikroskopu. Kuwanda uku kunotaridzika ndicho chimwe chezvinhu zvikuru vanachiremba vanoshandisa kuziva rudzi urwu rwe sarcoma.

UPS kazhinji inokura semasumbu akaoma, asingarwadzi, anogona kunge ari masendimita mashoma kusvika makuru. Vanhu vazhinji vanotanga kuona semasumbu anokura zvishoma nezvishoma kwemavhiki kana mwedzi.

Kenza iyi kazhinji inokanganisa vanhu vakuru vane makore 50 kusvika ku70, kunyange zvazvo inogona kuitika pazera ripi zvaro. Varume nevakadzi vanokanganiswa zvakafanana, uye inogona kuitika kune vanhu vemarudzi ose.

Ndeapi zviratidzo zve undifferentiated pleomorphic sarcoma?

Chiratidzo chokutanga cheUPS ndicho masumbu asingarwadzi aunonzwa pasi peganda rako. Masumbu aya kazhinji anonzwa akaoma kana akaoma kubata uye anogona kukura zvishoma nezvishoma nekufamba kwenguva.

Vanhu vazhinji havazvirwadzi pakutanga, izvo dzimwe nguva zvinoita kuti vanonoka kutsvaka rubatsiro rwechiremba. Heano mamwe ezviratidzo zvaunogona kuona:

• Masumbu akaoma, anokura chero kupi mumuviri mako
• Kuvirima munzvimbo yakakanganiswa
• Kurwadziwa kana kunzwa kusagadzikana, kunyanya sezvo tumor ikakura
• Kusakwanisa kufamba zvakanaka kana tumor ikakanganisa tsandanyama kana majoini
• Kunzwa kusanzwa kana kupisa kana tumor ikamanikidza mitsipa

Vamwe vanhu vanonzwa zviratidzo zvakasiyana zvichienderana nekwakakura tumor. Kana UPS ikakura mumukono wako kana gumbo, unogona kuona kushaya simba kana kuoma kufamba nechigunwe chacho.

Mu zviitiko zvisingawanzoitika, kana UPS ikakura munyama dziri mukati kana ikakanganisa nhengo dzemukati, unogona kunzwa zviratidzo zvakawanda senge kurasikirwa nehuremu pasina chikonzero, kuneta, kana kupisa. Zvisinei, izvi zviratidzo hazviwanzoitika uye kazhinji zvinoitika chete kana chirwere chacho chava chakakura.

Chii chinokonzera undifferentiated pleomorphic sarcoma?

Chikonzero chaicho che undifferentiated pleomorphic sarcoma hachizivisike zvizere, asi vatsvakurudzi vanofunga kuti inokura kana masero enyama yakapfava achichinja majeni awo zvichiita kuti akure zvisingadzoreki. Kuchinja uku kazhinji kunoitika pasina chikonzero pane kurigadzirwa kubva kuvabereki vako.

Zvinhu zvakati zvinogona kuita kuti UPS iite, kunyange zvazvo kuva nezvinhu izvi zvinokonzera hazvirevi kuti uchava nekensa iyi:

• Kurapwa nekuradhiya nekuda kwekenza imwe
• Kuwanikwa kwemakemikari kana zvinhu zvine chepfu
• Kuvirisa kwenguva refu kana kukuvara kwetishu yakapfava
• Zvimwe zvirwere zvemajeni zvinogara (zvisingawanzoitika)
• Kuchinja kwemasero nekukwegura kwenguva refu

Kurapwa nekuradhiya ndechimwe chezvinhu zvakakosha zvinokonzera. Kana wakamborapwa nekuradhiya nekuda kwekenza imwe makore apfuura, pane njodzi shoma yekuwana UPS munzvimbo yakamborapwa.

Zvisinei, zvakakosha kuziva kuti vanhu vazhinji vane UPS havazivi zvinhu zvinokonzera. Kensa iyi inoita sekukura pasina chikonzero kune vanhu vane hutano, izvo zvinogona kukunetsa kana uchiedza kunzwisisa kuti nei izvi zvakakukonzerai.

Rini unofanira kuona chiremba nekuda kwe undifferentiated pleomorphic sarcoma?

Unofanira kuona chiremba wako kana ukaona chero masumbu matsva anogara kwenguva yakareba kupfuura mavhiki mashoma, kunyanya kana ari kukura kana kuchinja. Kunyange zvazvo mazhinji emasumbu ari asina ngozi, zviri nani kuti aongororwe pakutanga.

Rongedza nguva nekukurumidza kana ukaona zviratidzo izvi zvekutyisidzira:

• Masumbu makuru kupfuura masendimita mashanu (5 centimeters) muhupamhi
• Chero masumbu ari kukura kana kuchinja maumbirwo
• Masumbu anonzwa akaoma kana akasimba munzvimbo
• Kurwadziwa, kusanzwa, kana kushaya simba munzvimbo yakakanganiswa
• Chero masumbu anokanganisa kufamba kwakajairwa

Usamirira kana masumbu ari kukunetsa kana kukanganisa mabasa ako ezuva nezuva. Kuonekwa pakutanga nekurapwa kazhinji kunounza migumisiro iri nani ne sarcomas.

Kana uine nhoroondo yekurapwa nekuradhiya, chenjera zvikuru nezve masumbu matsva munzvimbo dzakamborapwa. Kunyange zvazvo njodzi ichiri shoma, chiremba wako achida kuongorora chero masumbu matsva zvakanyanya.

Ndeapi njodzi dze undifferentiated pleomorphic sarcoma?

Kunzwisisa njodzi kunogona kukubatsira kuti urambe uchiri kuziva zviratidzo zvinogona kuitika, kunyange zvazvo kuva nenjodzi hazvirevi kuti uchava neUPS. Vanhu vazhinji vane kenza iyi havazivi zvinhu zvinokonzera.

Zvinhu zvikuru zvinokonzera njodzi izvo vanachiremba vakaziva zvinosanganisira:

• Zera riri pakati pemakore 50-70 (kunyange zvazvo inogona kuitika pazera ripi zvaro)
• Kurapwa nekuradhiya kare, kazhinji makore 10-20 apfuura
• Zvimwe zvirwere zvemajeni zvisingawanzoitika senge Li-Fraumeni syndrome
• Kuwanikwa kwemakemikari akati munzvimbo dzebasa
• Lymphedema refu (kuvirima kwenguva refu)

Kurapwa nekuradhiya ndicho chinhu chakakosha chinokonzera njodzi. Kana wakamborapwa nekuradhiya nekuda kwekensa yemukaka, lymphoma, kana kenza imwe, pane njodzi shoma yekuwana UPS munzvimbo yakarapwa makore mazhinji gare gare.

Zvimwe zvirwere zvemajeni zvinogonawo kuwedzera njodzi, asi izvi zvinosanganisira pasi pe 5% yezviitiko zveUPS zvose. Vanhu vazhinji vane UPS havazivi nhoroondo yemhuri yekenza uye havazivi kuti vane njodzi yemajeni.

Zvakakosha kucherechedza kuti zvinhu zvehupenyu senge kudya, kurovedza muviri, kana kusvuta hazvina kuoneka kuti zvinokanganisa njodzi yeUPS. Kensa iyi inoita sekukura nekuda kwechikonzero pane zvinhu zvinogona kudzivirirwa.

Ndeapi matambudziko anogona kuitika e undifferentiated pleomorphic sarcoma?

Kunyangwe vanhu vazhinji vane UPS vanogona kurapwa zvakanaka, kunzwisisa matambudziko anogona kuitika kunokubatsira kuti uzive zvaunofanira kutarisa uye rini unofanira kubata timu yako yehutano. Chidzvinyo chikuru cheUPS ndicho kukwanisa kwayo kupararira kune dzimwe nzvimbo dzemuviri wako kana isina kurapwa nekukurumidza.

Matambudziko akakomba anosanganisira:

• Metastasis (kupararira) kumapfupa, chiropa, kana dzimwe nhengo
• Kudzokera kwemuno mushure mekurapwa
• Kukuvara kwemitsipa kana tumor ikamanikidza mitsipa inokosha
• Kurasikirwa nebasa retsandanyama kana majoini akakanganiswa
• Matambudziko kubva pakuvhiya kana kurapwa kwakati

UPS ine tsika yekupararira kuburikidza neropa, mapapu ari nzvimbo yakajairika yekupararira. Ndokusaka chiremba wako achida kuita bvunzo dzemapapu sechikamu chekuongorora kwako kutanga nekutarisa zvinotevera.

Kudzokera kwemuno, uko kenza inodzokera munzvimbo imwechete mushure mekurapwa, kunogona kuitika kana masero ekensa asina kuonekwa achiripo mushure mekuvhiya. Ndokusaka kubviswa kwakakwana kwekuvhiya nemiganhu yakajeka kwakakosha kwazvo.

Mu zviitiko zvisingawanzoitika, matumor makuru anogona kukonzera matambudziko makuru usati watanga kurapwa. Izvi zvinogona kusanganisira kumanikidzwa kwemapoto eropa, mitsipa, kana nhengo, zvichienderana nenzvimbo ye tumor.

Undifferentiated pleomorphic sarcoma inoziviswa sei?

Kuziva UPS kunoda nhanho dzakati kuti uone rudzi rwekensa uye kuti yakapararira sei. Chiremba wako anotanga nekuongorora kwemuviri uye anozobva aita bvunzo dzakati kuti awane ruzivo rwakakwana.

Maitiro ekuongorora kazhinji anosanganisira:

1. Kuongorora kwemuviri nenhoroondo yekurapa
2. Bvunzo dzekuona (MRI, CT scan, kana ultrasound)
3. Biopsy kuongorora tishu pasi pemikroskopu
4. Bvunzo dzakawedzerwa kuona kana yakapararira (staging)
5. Kuongorora majeni etumor (mumamiriro ezvinhu akati)

Biopsy ndiyo nhanho inokosha nekuti ndiyo nzira chete yekuziva UPS. Chiremba wako achaburitsa chidimbu chidiki che tumor uchishandisa tsono kana kuburikidza nekucheka duku.

Bvunzo dzekuona dzinopa ruzivo rwakakwana pamusoro pehukuru nenhambo ye tumor, pamwe chete nehukama hwayo nezvinhu zviri pedyo senge ropa, mitsipa, nemapfupa. Ruzivo urwu runokosha pakuronga kurapwa kwako.

Bvunzo dzekuona kana yakapararira, dzinosanganisira X-rays yemapapu kana CT scans, dzinopa ruzivo rwakakwana kana kenza yakapararira kune dzimwe nzvimbo dzemuviri. Ruzivo urwu runokanganisa zvikuru sarudzo dzako dzekurapa uye zvinotarisirwa.

Kurapa kwe undifferentiated pleomorphic sarcoma ndekupi?

Kurapa kweUPS kazhinji kunosanganisira nzira dzakasiyana-siyana dzakagadzirirwa mamiriro ako chaiwo. Kuvhiya kazhinji ndiko kurapwa kukuru, kazhinji kunobatanidzwa nekurapwa nekuradhiya kana chemotherapy kuti ukwanise kurapwa zvakakwana.

Chirongwa chako chekurapwa chingasanganisira:

• Kuvhiya kubvisa tumor nemiganhu yakajeka
• Kurapwa nekuradhiya usati wavhiyiwa kana mushure mekuvhiya
• Chemotherapy, kunyanya kumatumor makuru kana ane grade yepamusoro
• Kurapwa kwakatarwa kana immunotherapy (mumamiriro ezvinhu akati)
• Kurapa nekutsigira

Kuvhiya kunangidzirwa kubvisa tumor yose pamwe ne tishu dzakapoteredza. Dzimwe nguva izvi zvinoda kubvisa tsandanyama dzakakanganiswa, uye mumamiriro ezvinhu asingawanzoitika, kucheka gumbo kunogona kudiwa, kunyange zvazvo kuvhiya kunogona kuchengetedza gumbo mumamiriro ezvinhu mazhinji.

Kurapwa nekuradhiya kunoshandisa ma beam ane simba kuti auraye masero ekensa uye kazhinji kunoitika usati wavhiyiwa kudzikisa tumor kana mushure mekuvhiya kuparadza masero ekensa achiripo. Nguva inoshandiswa inotsamira pane mamiriro ako chaiwo.

Chemotherapy inogona kukurudzirwa kana tumor yako iri hombe, ine grade yepamusoro, kana paine hanya yekupararira kwe masero asina kuonekwa. Kunyange zvazvo UPS isingapindure zvakanyanya ku chemotherapy, inogona kubatsira mumamiriro ezvinhu akati.

Timu yako yekurapa ichaita basa pamwe chete kuti iite chirongwa chinokupa mukana wakanaka wekurapwa uchichengetedza basa rakawanda sezvinobvira munzvimbo yakakanganiswa.

Nzira yekutarisira undifferentiated pleomorphic sarcoma pamba?

Kutarisira UPS pamba kunosanganisira kutarisira iwe pachako panguva yekurapwa nekudzoreredzwa uchitarisa chero kuchinja kunoda kutarisirwa kwechiremba. Kunyaradza kwako nekugara zvakanaka ndizvikamu zvakakosha zvezvirongwa zvako zve kurapwa.

Heano mamwe maitiro ekutsigira hutano hwako panguva yekurapwa:

• Tevedza chirongwa chako chekurapa sezvakanyorwa
• Chengetedza nzvimbo dzekuvhiya dzakachena uye dzakaoma sezvakarayirwa
• Chengetedza kudya kwakanaka kuti utsigire kuporesa
• Rambai muchiita zviitwa sezvakakurudzirwa nachiremba wenyu
• Tarisa zviratidzo zvehutachiona kana matambudziko

Cherechedza chero kuchinja munzvimbo yako yekuvhiya, senge kuwedzera kutsvuku, kuvirima, kupisa, kana kubuda. Izvi zvinogona kuva zviratidzo zvehutachiona zvinoda kutarisirwa kwechiremba nekukurumidza.

Kurovedza muviri zvinyoro-nyoro uye physiotherapy, sezvakakurudzirwa ne timu yako yehutano, kunogona kubatsira kuchengetedza simba nekufamba panguva yekudzoreredzwa. Usazvipindira zvakanyanya, asi kugara uchiita zviitwa zvakakwana kazhinji kunobatsira pakurapa.

Kutarisira migumisiro kubva ku chemotherapy kana radiation kunogona kusanganisira kudya zviduku, zvokudya zvakawanda kana uine manyoka, kugara wakanyorova, uye kuzorora zvakakwana kana uchinetseka.

Unofanira kugadzirira sei kuenda kuchiremba?

Kugadzirira kuenda kuchiremba kunobatsira kuve nechokwadi chekuti unowana zvakawanda kubva panguva yako ne timu yako yehutano. Kuva nemibvunzo yako nezvinetso zvako zvakarongeka kunogona kubatsira kuderedza kunetseka uye kuve nechokwadi chekuti hapana chinokosha chinokanganwika.

Usati waenda kuchiremba,unganidza ruzivo urwu:

• Ruzivo rwezvinodhaka zvaunotora nezvimwe zvinhu zvaunotora
• Nhoroondo yako yekurapa yakazara, kusanganisira kenza dzakapfuura
• Nhoroondo yemhuri yekenza kana zvirwere zvemajeni
• Chero bvunzo dzekuona kana migumisiro yebvunzo kubva kune vamwe vanachiremba
• Ruzivo rweinshurensi nemafomu ekutumira kana zvichidiwa

Nyora mibvunzo yako usati waenda kuti usakanganwe panguva yekushanya kwako. Mibvunzo yakajairika inogona kusanganisira kubvunza nezve sarudzo dzekurapa, migumisiro inogona kuitika, zvinotarisirwa, uye kuti kurapwa kunogona kukanganisa sei hupenyu hwako hwezuva nezuva.

Funga kuuya neshamwari yakavimbika kana nhengo yemhuri kuti ikubatsire kurangarira ruzivo rwakataurwa panguva yekushanya kwako. Kuva nekutsigira kwemanzwiro kunogonawo kubatsira kana uri kurapwa nekensa.

Usazengurire kubvunza chiremba wako kuti atsanangure chero chinhu chisinganzwisisiki. Zvakakosha kuti unzwe uchigona kurapwa kwako uye unoziva zvaunofanira kutarisira.

Chii chinokosha chekuziva nezve undifferentiated pleomorphic sarcoma?

Undifferentiated pleomorphic sarcoma ikensa isingawanzoitika asi inorapika inoda kutarisirwa kwechiremba nekukurumidza nekurapwa kwakakwana. Kunyange zvazvo kuziva izvi kungaita kuti unzwe uchitya, vanhu vazhinji vane UPS vanogona kurapwa zvakanaka, kunyanya kana kenza yakawanikwa pakutanga uye isina kupararira kune dzimwe nzvimbo dzemuviri.

Chinhu chakakosha ndechekuti kuonekwa pakutanga nekurapwa ne timu ine ruzivo rwe sarcoma zvinowedzera migumisiro. Kana ukaona chero masumbu anokura, usamirira kuti aongororwe.

Mamiriro emunhu mumwe nemumwe akaoma, uye chirongwa chako chekurapwa chichagadzirirwa zvaunoda. Kubata ne timu yako yehutano, kubvunza mibvunzo, uye kuramba uchiudzwa nezve mamiriro ako zvichakubatsira kuti unzwe uchikwanisa kutonga rwendo rwako.

Kunyangwe nzira iri pamberi ichioneka yakaoma, yeuka kuti kufambira mberi mukurapa kwe sarcoma kuri kuramba kuchivandudza migumisiro yevanhu vane UPS. Timu yako yekurapa iripo kukutsigira nhanho imwe neimwe.

Mibvunzo inowanzo bvunzwa nezve undifferentiated pleomorphic sarcoma

Q.1 Undifferentiated pleomorphic sarcoma inogara ichiuraya here?

Kwete, UPS haigari ichiuraya. Vanhu vazhinji vane UPS vanogona kurapwa, kunyanya kana kenza yakawanikwa pakutanga uye isina kupararira kune dzimwe nzvimbo dzemuviri. Zvinotarisirwa zvinoenderana nezvinhu senge hukuru nenhambo ye tumor, kana yakapararira, uye kuti inopindura sei kurapwa. Nekurapwa kwakakodzera kubva kune timu ine ruzivo rwe sarcoma, varwere vazhinji vanorarama hupenyu hunowanzoitika, hune hutano.

Q.2 Undifferentiated pleomorphic sarcoma inogona kudzokera mushure mekurapwa here?

Hungu, UPS inogona kudzokera mushure mekurapwa, kunyange zvazvo izvi zvisingawanzoitiki kune munhu wese. Kudzokera kwemuno munzvimbo imwechete kunoitika mu 10-20% yezviitiko, nepo kudzokera kure (metastasis) kushoma. Ndokusaka zvakakosha kuita bvunzo dzekutarisa zvinotevera. Kuonekwa pakutanga kwe chero kudzokera kunobvumira kurapwa nekukurumidza, izvo zvinogona kunge zvichiri kushanda zvakanyanya.

Q.3 Undifferentiated pleomorphic sarcoma inokura nekukurumidza sei?

UPS kazhinji inokura zvishoma nezvishoma kwemavhiki kusvika kumwedzi, kunyange zvazvo kukura kunogona kusiyana kubva kune munhu kune mumwe. Matumor mamwe anogona kukura nekukurumidza, nepo mamwe achikura zvishoma nezvishoma kwenguva yakareba. Grade ye tumor, inotsanangura kuti masero ekensa anotaridzika sei pasi pemikroskopu, inogona kupa vanachiremba pfungwa yekuti inogona kukura nekukurumidza sei uye kupararira.

Q.4 Ndichacheka gumbo here kana ndine undifferentiated pleomorphic sarcoma?

Kucheka gumbo kunowanzodiwa kune UPS. Mumamiriro ezvinhu mazhinji, kuvhiya kunogona kubvisa tumor uchichengetedza gumbo. Matekinoroji matsva ekuvhiya, pamwe chete nekurapwa nekuradhiya, anobvumira vanachiremba kuti vawane kudzora kenza zvakanaka vachichengetedza basa. Kucheka gumbo kunongofungwa mumamiriro ezvinhu asingawanzoitika apo zvakakosha kubvisa kenza yose.

Q.5 Undifferentiated pleomorphic sarcoma inogara ichigara mumhuri here?

UPS haigari ichigara mumhuri. Pasi pe 5% yezviitiko zvinobatanidzwa nezvirwere zvemajeni zvinogara senge Li-Fraumeni syndrome. Vanhu vazhinji vane UPS havazivi nhoroondo yemhuri yerudzi urwu rwekensa uye havazivi kuti vane njodzi yemajeni. Kensa iyi kazhinji inokura nekuda kwe kuchinja kwemajeni kunoitika muhupenyu hwemunhu pane kurigadzirwa kubva kuvabereki.