Chii Chinonzi Chirwere cheWilson? Zviratidzo, Zvinokonzera, & Kurapa

Chirwere cheWilson chirwere chisingawanzoitika chinowanikwa nemagwenya umo muviri wako usingakwanisi kubvisa koppa zvakakwana, zvichiita kuti iunganidzwe muchiropa chako, uropi, nemamwe matunhu emuviri. Kuunganidzwa uku kwekoppa kunoitika nekuti unogara uchitakura majini asina kunaka kubva kuvabereki vako vose anokanganisa kuti muviri wako unogadzirisa sei mineral iyi inokosha.

Kunyangwe koppa ichibatsira muviri wako muzvikamu zviduku, yakawanda inorova nekufamba kwenguva. Chirwere ichi chinotapukira vanhu vanosvika 1 pavagumi ve30,000 pasi rose, uye zviratidzo zvinowanzoonekwa pakati pemakore 5 ne35, kunyangwe zvingaoneka kare kana gare gare mune dzimwe nyaya.

Ndeapi zviratidzo zvechirwere cheWilson?

Zviratidzo zvechirwere cheWilson zvakasiyana-siyana zvichienderana nekuti ndeapi matunhu emuviri akanyanya kukanganiswa nekuunganidzwa kwekoppa. Zviratidzo zvepakutanga zvinogona kunge zvisina kunaka uye zviri nyore kukanganisa nezvimwe zvirwere, ndosaka vanhu vazhinji vasingawanikwi pakarepo.

Zviratidzo zvakajairika zvaunogona kuona zvinosanganisira:

• Kuneta uye kushaya simba kunoshaya kugadziriswa nekuzorora
• Kurwadziwa mudumbu kana kuzvimba munzvimbo yemudumbu rako
• Kuyerera kweganda rako kana maziso (jaundice)
• Kutetemeka kana kudedera, kunyanya mumaoko ako
• Kunetseka kutaura zvakanaka kana kutaura kwakanyanyisa
• Matambudziko ekurongeka uye kuenzana
• Kusimba mumasumbu ako
• Kushanduka kwemanzwiro, kuora mwoyo, kana kunetseka
• Kunetseka kuisa pfungwa kana matambudziko ekurangarira

Vamwe vanhu vanogadzirawo zvidzitiro zvebrown kana girini-girini pamativi emaziso avo zvinonzi Kayser-Fleischer rings. Aya mazinga ndeakuunganidzwa kwekoppa uye anogona kuonekwa panguva yekutarisa maziso, kunyangwe asingawanikwi kune munhu wese ane chirwere cheWilson.

Mune zviitiko zvakakomba, unogona kuwana kukundikana kwechiropa kamwe kamwe, zviratidzo zvakakomba zvehuropi senge kunetseka kumira, kana kushanduka kukuru kwepfungwa. Aya maratidzo akakomba anoda rubatsiro rwekurapa nekukurumidza uye haafaniri kuregererwa.

Ndeapi marudzi echirwere cheWilson?

Chirwere cheWilson chinowanzosiyaniswa zvichienderana nezviratidzo zvinoonekwa kutanga uye matunhu emuviri akanyanya kukanganiswa. Kunzwisisa marudzi aya kunobatsira vanachiremba kugadzira chirongwa chakakodzera chekurapa kwauri.

Rudzi rwechiropa runokanganisa chiropa chako zvikuru uye runowanzoonekwa muvana nechirikadzi. Unogona kuona kuneta, kurwadziwa mudumbu, kana zviratidzo zvematambudziko echiropa senge jaundice usati waona chero zviratidzo zvine chekuita neuropi.

Rudzi rwehuropi runokanganisa uropi hwako uye sisitimu yematumbu, kazhinji rinoonekwa muvakuru vaduku. Iyi fomu kazhinji inokonzera matambudziko ekufamba, kudedera, kunetseka kutaura, uye matambudziko ekurongeka sezviratidzo zvepakutanga zvinoonekwa.

Rudzi rwepfungwa runokanganisa manzwiro ako nemafambisirwo ako, zvichikonzera kuora mwoyo, kunetseka, kushanduka kwepfungwa, kana kunetseka kufunga zvakanaka. Iyi fomu inogona kunge iri yakaoma kunzwisisa nekuti zviratidzo zvinoenderana nezvirwere zvepfungwa zvakajairika.

Vamwe vanhu vanowana rudzi rwakasanganiswa umo zviratidzo zvechiropa, uropi, uye zvepfungwa zvose zvinoonekwa pamwe chete kana nekukurumidza. Iyi musanganiswa inogona kuita kuti kuongororwa kuve kwakaoma asi zvakare inopa mazano akawanda kune timu yako yekurapa.

Chii chinokonzera chirwere cheWilson?

Chirwere cheWilson chinokonzerwa nekushayikwa kwegene rinonzi ATP7B rinodzora kuti muviri wako unogadzirisa sei koppa. Unogara uchitakura chirwere ichi kubva kuvabereki vako, uye unofanira kugamuchira kopi isina kunaka yegene kubva kuna amai vako nababa kuti ubude nechirwere.

Gene rako reATP7B rinowanzoita puroteni inobatsira kufambisa koppa kubva muchiropa chako kuenda mubile rako, rinobva raendesa koppa kubva mumuviri wako kuburikidza nesimba rako rekudiridzira. Kana gene iri isingashande zvakanaka, koppa inotanga kuunganidzwa muchiropa chako panzvimbo yekubviswa.

Nekufamba kwenguva, kuunganidzwa uku kwekoppa kunorova uye kunotanga kukuvadza masero echiropa rako. Kana chiropa chako chisingakwanisi kuchengeta koppa yakawanda zvakachengeteka, koppa yakawandisa inopinda muropa rako uye inofamba kuenda kune mamwe matunhu emuviri senge uropi hwako, itsvo, uye maziso.

Huwandu hwekoppa hunounganidzwa uye kuti inounganidzwa nekukurumidza sei inosiyana kubva kune munhu kune mumwe munhu, kunyangwe mumhuri imwe chete. Izvi zvinotsanangura kuti nei vamwe vanhu vachiwana zviratidzo pakutanga kwehudiki nepo vamwe vasingaoni matambudziko kusvika vave vakuru.

Rini unofanira kuona chiremba nekuda kwechirwere cheWilson?

Unofanira kuona chiremba kana uine zviratidzo zvinogara zvichiratidza chirwere cheWilson, kunyanya kana uine nhoroondo yemhuri yechirwere ichi. Kuongororwa nekukurumidza uye kurapwa kunogona kudzivirira matambudziko akakomba uye kukubatsira kuchengetedza hupenyu hwakanaka.

Taura nachiremba wako kana ukaona kuneta kunogara kwenguva refu, kurwadziwa mudumbu kusina tsananguro, kudedera, kana kushanduka mukurongeka kwako kunogara kwemavhiki anopfuura mashoma. Aya maratidzo anogona kunge asingabatani, asi pamwe chete anogona kuratidza chirwere cheWilson.

Tsvaga rubatsiro rwekurapa nekukurumidza kana ukawana zviratidzo zvakakomba kamwe kamwe senge kurwadziwa kwakanyanya mudumbu, kuyerera kweganda rako kana maziso, kusanzwisisa, kana kunetseka kumira. Aya maratidzo anogona kuratidza kuti mazinga ekoppa asvika pamwero unotyisa uye anoda kurapwa nekukurumidza.

Kana uine nhengo dzemhuri dzine chirwere cheWilson, zvakakosha kuti uongororwe kunyangwe uchinzwa zvakanaka. Kuongororwa kwemagwenya uye kuongororwa kunogona kuona chirwere ichi usati waona zviratidzo, zvichibvumira kurapwa nekukurumidza kunodzivirira kukuvara kwezvikamu zvemuviri.

Ndeapi njodzi dzechirwere cheWilson?

Njodzi huru yechirwere cheWilson ndeyekuve nevabereki vane gene reATP7B risina kunaka. Sezvo iri chirwere chemagwenya chinowanzoitika, unofanira kutora kopi isina kunaka kubva kumubereki mumwe nemumwe kuti ubude nechirwere.

Rudzi rwako runogona kukanganisa njodzi yako zvishoma, sezvo mamwe marudzi ane huwandu hwakakwira hwekutakura gene rechirwere cheWilson. Vanhu vekuEastern Europe, Mediterranean, kana Middle East vane huwandu hwakakwira zvishoma, kunyangwe chirwere ichi chinogona kukanganisa munhu wese pasinei nerudzi rwavo.

Kuve nehama dzine chirwere cheWilson kunowedzera njodzi yako zvakanyanya, sezvo munogovana vabereki vakaenzana uye nhoroondo yemagwenya. Kana mumwe wehama dzako kana hanzvadzi dzako akaongororwa, une mukana we25% wekuvawo nechirwere ichi.

Zera haringakonzere chirwere cheWilson zvakananga, asi rinoita kuti zviratidzo zviwanzoonekwa. Vanhu vazhinji vanowana zviratidzo pakati pemakore 5 ne35, kunyangwe dzimwe nyaya dzisingawanzoitika dzicharatidza zviratidzo muhudiki kana gare gare muhupenyu hwevakuru.

Ndeapi matambudziko anogona kuitika echirwere cheWilson?

Pasina kurapwa kwakakodzera, chirwere cheWilson chinogona kukonzera matambudziko akakomba sezvo koppa ichigara ichikwira muzvikamu zvemuviri wako. Mashoko akanaka ndeaekuti akawanda ematambudziko aya anogona kudzivirirwa kana kutungamirwa nekurapa kwakakodzera.

Matambudziko akajairika aunogona kusangana nawo anosanganisira:

• Cirrhosis yechiropa kana kuita mavara kunokanganisa basa rechiropa
• Kukundikana kwechiropa kwakakomba kunoda kurapwa nekukurumidza
• Kukuvara kwenguva refu kwehuropi kunokanganisa kufamba nekutaura
• Matambudziko etsvo kubva pakukuvadzwa nekuppa
• Matambudziko emwoyo
• Matambudziko emwongo nemapfupa
• Zviratidzo zvakakomba zvepfungwa zvinosanganisira psychosis

Mune zviitiko zvisingawanzoitika, chirwere cheWilson chisingarapwi chinogona kukonzera kukundikana kwechiropa kunouraya kana kukuvara kwakakomba kwehuropi. Vamwe vanhu vanogona kuwana mamiriro anonzi hemolytic anemia, umo koppa inokuvadza masero matsvuku eropa uye inoita kuti aparare nekukurumidza kupfuura kazhinji.

Pamimba inogona kuunza matambudziko chaiwo kune vakadzi vane chirwere cheWilson, sezvo mazinga ekoppa angashanduka uye kugadziriswa kwemishonga kungadiwa. Zvisinei, nekutarisa kwakakodzera nekutarisirwa, vakadzi vazhinji vane chirwere cheWilson vanogona kuva nepamuviri nevana vane utano.

Chirwere cheWilson chinoongororwa sei?

Kuongorora chirwere cheWilson kunoda bvunzo dzakasiyana-siyana nekuti hapana bvunzo imwe chete inogona kusimbisa chirwere ichi. Chiremba wako anogona kutanga nebvunzo dzeropa kuti aone mazinga ako ekoppa uye basa rechiropa.

Bvunzo dzekuongorora dzakajairika dzinosanganisira kuyeresa ceruloplasmin (puroteni inotakura koppa muropa rako), kuongorora mazinga ako ekoppa muviri wemaawa makumi maviri nemana, uye kuongorora basa rechiropa rako kuburikidza nebasa reropa. Ceruloplasmin yakaderera pamwe chete nekuppa yakawanda muviri kazhinji inoratidza chirwere cheWilson.

Chiremba wako achaitawo bvunzo yemaziso kuti aone Kayser-Fleischer rings, aya mazinga ekoppa ari pamativi ecornea yako. Kunyangwe kwete munhu wese ane chirwere cheWilson ane aya mazinga, kuawana kunosimbisa zvakanyanya kuongororwa.

Kuongororwa kwemagwenya kunogona kusimbisa kuongororwa nekutsvaga kushayikwa kwegene reATP7B. Bvunzo iyi inobatsira zvikuru kune nhengo dzemhuri dzinoshuvira kuziva kana dzine chirwere ichi, kunyangwe dzisina zviratidzo zvichiri.

Mune dzimwe nyaya, chiremba wako anogona kukurudzira biopsy yechiropa kuti aone zvakananga mazinga ekoppa mune tishu yechiropa rako. Iyi nzira inosanganisira kutora sampuli diki yetishu yechiropa kuti iongororwe uye inopa kuyerwa kwakanyanya kwekuunganidzwa kwekoppa.

Kurapa kwechirwere cheWilson ndechii?

Kurapa kwechirwere cheWilson kunotarisa pakubvisa koppa yakawandisa mumuviri wako uye kudzivirira kuunganidzwa kwakawanda. Nekurapa kwakakodzera, vanhu vazhinji vanogona kurarama hupenyu hunowanzoitika, hune utano uye kudzivirira matambudziko akakomba.

Mishonga huru inoshandiswa ndeye chelating agents inobatanidza nekuppa uye inobatsira muviri wako kuibvisa kuburikidza nemiriro. Penicillamine ne trientine ndidzo chelators dzakanyanya kunyorwa, uye dzinoshingaira nekubata pamolekyuli dzekoppa uye kuendesa kunze kwemuviri wako.

Zvimwe zvekudya zveZinc zvinomiririra imwe nzira yekurapa inoshanda nekudzivirira koppa kubva mukati memudumbu rako. Panzvimbo yekubvisa koppa iripo, zinc inodzivirira koppa itsva kubva kupinda mumuviri wako uye kazhinji inoshandiswa kurapa kwenguva refu.

Chiremba wako achaongorora kufambira mberi kwako nekurapa kuburikidza nebvunzo dzeropa nemiriro nguva dzose kuti aone kuti mishonga inoshanda zvakanaka uye kugadzirisa zvikamu sezvinodiwa. Vanhu vazhinji vanoda kutora mishonga kweupenyu hwese kuti vachengete mazinga ekoppa pasi pekudzora.

Mune zviitiko zvakakomba apo kukuvara kwechiropa kwakakura, kuisirwa kwechiropa kunogona kudiwa. Izvi zvinowanzochengeterwa vanhu vane kukundikana kwechiropa kamwe kamwe kana cirrhosis yakakomba avo vasingapindure kurapwa kwemishonga.

Nzira yekutungamira sei chirwere cheWilson pamba?

Kutungamira chirwere cheWilson pamba kunosanganisira kutevera chirongwa chako chemishonga zvakavimbika uye kuita mamwe magadzirirwo ekudya kuti ubatsire kurapwa kwako. Kuenderera mberi nemishonga yako yakanyorwa kwakakosha zvikuru pakuchengetedza mazinga ekoppa pasi pekudzora.

Uchada kuderedza zvekudya zvine koppa yakawanda, kunyanya mugore rekutanga re kurapwa apo muviri wako uri kushanda kubvisa koppa yakawandisa. Zvekudya zvekudzivisa kana kuderedza zvinosanganisira chiropa, shellfish, nati, chocolate, howa, uye michero yakaoma.

Kutora mishonga yako panguva yakakodzera uye nezvekudya zvakakodzera zvinokosha pakushanda kwavo. Mishonga yeChelating inoshanda zvakanaka kana ikatengwa mudumbu risina chinhu, nepo zinc inofanira kutengwa pakati pezvokudya kuti iwedzere kunwa uye kuderedza kurwadziwa mudumbu.

Kuita zvemitambo nguva dzose kunogona kubatsira kuchengetedza hutano hwako hwese uye kunogona kubatsira basa rechiropa, kunyangwe unofanira kukurukura mazinga akakodzera emishonga nachiremba wako. Zviitiko zvinononoka senge kufamba, kushambira, kana yoga zvakachengeteka uye zvinobatsira.

Kudzivisa doro kwakakosha nekuti kunogona kuipa kukuvara kwechiropa uye kukanganisa kurapwa kwako. Kunyangwe zvikamu zviduku zvedoro zvinogona kukuvadza kana chiropa chako chakanyanya kushanda nekukuvadzwa nekuppa.

Unofanira kugadzirira sei kuonana nachiremba wako?

Kugadzirira kuonana nachiremba wako kunobatsira kuve nechokwadi chekuti unowana zvakanyanya kubva pakushanya kwako uye kupa timu yako yekurapa ruzivo rwavanoshuvira kukubatsira zvakakwana. Tanga nekunyora zviratidzo zvako zvese, kunyangwe izvo zvinoita sekusabatana.

Gadzira runyorwa rwemishonga yese nezvimwe zvekudya zvauri kutora ikozvino, kusanganisira zvikamu uye kuti unotora sei kazhinji. Izvi zvinosanganisira mishonga inotengeswa pasina chinyorwa chechiremba nemavhitamini, sezvo zvimwe zvinogona kukanganisa kurapwa kwechirwere cheWilson.

Unganidza ruzivo nezve nhoroondo yemhuri yako yekurapa, kunyanya chero hama dzave dzine matambudziko echiropa, zvirwere zvehuropi, kana zvirwere zvepfungwa. Kana uchiri kuziva chero nhengo dzemhuri dzine chirwere cheWilson, taura nezvezvinhu izvozvo kuti ugozvipa.

Nyora mibvunzo yaunoda kubvunza chiremba wako usati waenda kuonana naye kuti usakanganwa panguva yekushanya kwako. Funga kubvunza nezve nzira dzekurapa, kushanduka kwehupenyu, zvinodiwa pakutarisa, uye zvaunofanira kutarisira kuenda mberi.

Uya neshamwari yakavimbika kana nhengo yemhuri kuonana kwako kana zvichibvira, kunyanya kana uri kunetseka nekurangarira kana kuisa pfungwa. Vanogona kukubatsira kurangarira ruzivo rwakakosha uye kupa rutsigiro rwemanzwiro.

Chii chinonyanya kukosha nezve chirwere cheWilson?

Chirwere cheWilson chirwere chemagwenya chinogona kutungamirwa chinoda kurapwa kweupenyu hwese asi hachifanire kuderedza hupenyu hwako. Chinhu chakakosha chokurangarira ndechekuti kuongororwa nekukurumidza uye kurapwa kwenguva dzose kunogona kudzivirira matambudziko akakomba uye kukubatsira kurarama zvakajairika.

Kunyangwe kuongororwa kungaita sekutyisa pakutanga, vanhu vazhinji vane chirwere cheWilson vanoenderera mberi vachiva nebasa rabudirira, hukama, nemhuri nekurapa kwakakodzera. Chinhu chikuru ndechekushanda pedyo netimu yako yekurapa uye kuramba wakazvipira kuchirongwa chako chekurapa.

Rangarira kuti chirwere cheWilson chinotapukira munhu wese zvakasiyana, saka ruzivo rwako harufanire kuenderana nezvaunoverenga online kana kunzwa kubva kune vamwe. Tarisa pachirongwa chako chekurapa uye kufambira mberi, uye usambotya kutaura nachiremba wako nemibvunzo kana zvinetso.

Mibvunzo inowanzo bvunzwa nezve chirwere cheWilson

Chirwere cheWilson chinogona kupora zvachose here?

Chirwere cheWilson hachigone kupora, asi chinogona kutungamirwa zvakakwana nekurapwa kweupenyu hwese. Vanhu vazhinji vanowana kurapwa kwakakodzera vanogona kudzivirira kukuvara kwakawanda kwezvikamu zvemuviri uye kurarama hupenyu hunowanzoitika, hune utano. Chinhu chikuru ndechekutanga kurapwa nekukurumidza uye kutora mishonga nguva dzose sezvakanyorwa nachiremba wako.

Ndichapa chirwere cheWilson kuvana vangu here?

Kana uine chirwere cheWilson, mumwe nemumwe wevana vako ane mukana we50% wekuva mutariri uye mukana mudiki wekuva nechirwere icho pachacho. Mukomana wako achadawo kuva mutariri kuti mwana wako aite chirwere cheWilson. Kuita mazano emagwenya kunogona kukubatsira kunzwisisa njodzi chaiyo uye sarudzo dzemhuri yako.

Zvinotora nguva yakareba sei kuti kurapwa kushande?

Unogona kutanga kunzwa zvakanaka mukati memwedzi mishoma yekutanga kurapwa, asi zvinogona kutora makore 1-2 kuti uone kugadziriswa kukuru muzviratidzo zvehuropi. Basa rechiropa kazhinji rinowedzera nekukurumidza, dzimwe nguva mukati memavhiki kusvika kumwedzi. Chiremba wako achaongorora kufambira mberi kwako kuburikidza nebvunzo dzeropa nguva dzose uye kugadzirisa kurapwa sezvinodiwa.

Ndingararama hupenyu hunowanzoitika here ndine chirwere cheWilson?

Hungu, vanhu vazhinji vane chirwere cheWilson vanogona kurarama hupenyu hunowanzoitika zvachose nekurapa kwakakodzera. Unogona kushanda, kuita zvemitambo, kuva nehukama, uye kutanga mhuri senge munhu wese. Chinhu chikuru ndechekutora mishonga yako nguva dzose uye kutevera netimu yako yekurapa nguva dzose.

Chii chinoitika kana ndikarega kutora mishonga yangu?

Kurega mishonga yako yeWilson kunogona kuva ngozi nekuti koppa ichagara ichikwira muzvikamu zvemuviri wako zvakare. Izvi zvinogona kukonzera matambudziko akakomba anosanganisira kukundikana kwechiropa, matambudziko ehuropi, kana zviratidzo zvepfungwa. Kana uri kunetseka nemishonga yako iripo, taura nachiremba wako nezvemamwe masarudzo panzvimbo pekurega kurapwa zvachose.