X-Linked Agammaglobulinemia

X-linked agammaglobulinemia (a-gam-uh-glob-u-lih-NEE-me-uh), inozivikanwawo seXLA, chirwere chema immune system chinopfuudzwa kubva kumhuri, chinonzi chinogara. XLA inoita kuti zviomere kurwisa hutachiona. Vanhu vane XLA vangave nehutachiona hwemukati me nzeve, sinuses, respiratory tract, bloodstream nemidziyo yemukati. XLA inowanzokanganisa varume. Asi vakadzi vanogona kutakura majini akabatana nechirwere ichi. Vanhu vakawanda vane XLA vanoonekwa panguva yevacheche kana muhudiki, mushure mekunge vave nehutachiona kakawanda. Vamwe vanhu havaonekwi kusvika vave vakuru.

Vana vazhinji vane XLA vanoonekwa vakagwinya mumwedzi mishomanana yekutanga. Vanodzivirirwa nemapuroteni anonzi antibodies aakawana kubva kunaamai vavo vasati vaberekwa. Kana aya antibodies abuda mumuviri wavo, vana vanotanga kuwana hutachiona hwebhakitiriya kakawanda. Hutachiona uhwu hunogona kuuraya. Hutachiona hunogona kusanganisira nzeve, mapapu, sinuses neganda. Vacheche vevarume vakaberekwa vane XLA vane: Matonsi madiki kwazvo. Lymph nodes diki kana kuti hapana.

X-linked agammaglobulinemia inokonzerwa nechinja muchiitiko chejini. Vanhu vane chirwere ichi havawanzo gadzira mapuroteni anozivikanwa se antibodies anorwisa hutachiona. Anenge 40% yevanhu vane chirwere ichi vane nhengo yemhuri ine chirwere icho.