Zoster-Ellison Syndrome Chii? Zviratidzo, Zvinokonzera, & Kurapa

Zoster-Ellison syndrome chirwere chisingawanzoitika apo zvimwe zvinhu zviri mu pancreas yako kana mumatumbo maduku zvinogadzira asidhi yakawanda yemudumbu. Aya ma tumors, anonzi gastrinomas, anoburitsa hormone inoudza mudumbu rako kuti rigadzire asidhi yakawanda, izvo zvinotungamira pakukuvara kwematumbo kunorwadza uye matambudziko ekugaya chikafu.

Iyi chirwere chinotapura vanhu vangangosvika 1 kusvika 3 pamuwana mumwe chete gore rega rega, zvichiita kuti ive isingawanzoitika. Kunyange zita rayo richinzwa richitya, kunzwisisa zviri kuitika mumuviri wako kunogona kukubatsira kushanda nesangano rehutano hwako kuti utungamirire zviratidzo zvakanaka.

Zviratidzo zveZoster-Ellison syndrome ndeapi?

Chiratidzo chakajairika chaungave nacho kurwadziwa kwemudumbu kunogara kwenguva refu, kunyanya mudumbu rako repamusoro. Iyi kurwadziwa kazhinji inonzwa sekuvheneka uye inogona kuipa kana mudumbu rako risina chinhu kana usiku.

Mhinduro yemuviri wako kune asidhi yakawanda yemudumbu inogona kugadzira zviratidzo zvakawanda zvisingafadzi izvo zvinowanzo kuitika zvishoma nezvishoma:

• Kukuvadzwa kwematumbo kunogara kwenguva refu kunorasikirwa nekurapwa kwakajairwa
• Heartburn yakakomba kana acid reflux inonzwa yakanyanya kupfuura indigestion yakajairwa
• Diarrhea inogara kwenguva refu, kazhinji mvura uye kazhinji
• Kusvotwa uye kurutsa, kunyanya mushure mekudya
• Kurasikirwa nechido chekudya kunotungamira pakurasikirwa uremu usingatarisirwi
• Kutemwa uye kunzwa wakazara nekukurumidza panguva yekudya

Mumazuva amwe, ungave nezviratidzo zvisingawanzoitika senge kuoma kumeza kana kurwadziwa pachipfuva. Aya maratidzo anogona dzimwe nguva kunyengera mamwe mamiriro ekugaya chikafu, ndosaka kuwana chirwere chakanyatsojeka kuchikosha.

Chii chinokonzera Zoster-Ellison syndrome?

Zoster-Ellison syndrome inoitika kana gastrinomas ikaunda mu pancreas yako kana pamusoro pematumbo ako maduku anonzi duodenum. Aya ma tumors anoshanda senge mafekitari madiki, achigadzira hormone yakawanda inonzi gastrin.

Kana mazinga e gastrin akawanda zvakanyanya, mudumbu rako rinopindura nekugadzira asidhi yakawanda kupfuura iyo muviri wako unoda. Funga nezvazvo senge thermostat iri pamusoro - mudumbu rako rinoramba richigadzira asidhi kunyangwe painofanira kurega.

Gastrinomas yakawanda inoitika pasina chikonzero chakajeka, asi anenge 25% ezviitiko zvinoitika sechitsiko chechirwere chemagene chinonzi Multiple Endocrine Neoplasia type 1 (MEN1). Kana uine MEN1, une mukana mukuru wekuwana ma tumors mune dzakawanda hormone-producing glands mumubiri wako.

Chikonzero chaicho chekuti aya ma tumors anoita hachizivisike zvizere mune akawanda mamiriro. Nekudaro, vatsvakurudzi vanotenda kuti kusanganiswa kwezvinhu zvemagene uye zvimwe zvinhu zvakapoteredza zvine basa mukukura kwavo.

Marudzi eZoster-Ellison syndrome ndeapi?

Vanachiremba kazhinji vanotsanangura Zoster-Ellison syndrome zvichienderana nekuti inoitika yoga kana sechitsiko chechirwere chemagene chakakura. Kunzwisisa aya marudzi kunobatsira kutungamira nzira yako yekurapa.

Sporadic Zoster-Ellison syndrome inoumba anenge 75% ezviitiko uye inoitika yoga pasina chero chirwere chemagene chinogona kuwanikwa. Munzira iyi, kazhinji une gastrinoma imwe kana dzakawanda, uye kazhinji dziri mu pancreas yako kana duodenum.

Rudzi rumwe rwakaita neMEN1 syndrome, chirwere chinogona kuwanikwa chinokanganisa dzakawanda hormone-producing glands. Kana uine fomu iri, une mukana mukuru wekuwana gastrinomas diki dzakawanda uye ungavewo une ma tumors mu parathyroid glands yako kana pituitary gland.

Chiremba wako achaona rudzi rwawakaita kuburikidza nekuongororwa kwemagene uye kuongororwa kwakanyatsojeka kwehunhu hwako hwe tumor. Ruzivo urwu runovabatsira kugadzira chirongwa chekurapa chakakodzera mamiriro ako chaiwo.

Rini unofanira kuona chiremba nezve Zoster-Ellison syndrome?

Unofanira kubata nehutano hwako kana uine kurwadziwa kwemudumbu kunogara kwenguva refu kunorasikirwa nekurapa kwakajairwa kana kuchinja kwezvokudya. Izvi zvinokosha zvikuru kana kurwadziwa kuchikanganisa mabasa ako ezuva nezuva kana hope.

Tsvaka rubatsiro rwechiremba nekukurumidza kana ukaona zviratidzo zvinogara zvakaita se heartburn yakakomba, diarrhea inogara kwenguva refu, kana kurasikirwa uremu usingazivikanwe. Aya maratidzo, kunyanya kana achiitika pamwe chete, anoda kuongororwa nemunyanzvi.

Fonera chiremba wako nekukurumidza kana uine zviratidzo zvinogona kuratidza kukuvadzwa kwematumbo, sekurutsa ropa, matumbo madema kana akasviba, kana kurwadziwa kwemudumbu kwakakomba. Aya maratidzo anoda rubatsiro rwekukurumidza rwechiremba.

Kana uine nhoroondo yemhuri yeMEN1 syndrome kana ma tumors akawanda endocrine, kurukura nezvekuongororwa nezvinhu nehutano hwako kunyangwe usina zviratidzo zvakadaro. Kuonekwa pakutanga kunogona kuita musiyano mukuru mumagumisiro ako ekurapa.

Zvinhu zvinowedzera mukana weZoster-Ellison syndrome ndeapi?

Zvinhu zvakawanda zvinogona kuwedzera mukana wako wekuwana Zoster-Ellison syndrome, kunyangwe kuva nezvinhu izvi hazvirevi kuti iwe uchava nechinetso ichi. Kunzwisisa izvi kunokubatsira iwe nechikura wako kuti mugare makangwarira nezviratidzo zvepakutanga.

Chinhu chakakosha chinowedzera mukana ndechekuva neMultiple Endocrine Neoplasia type 1 (MEN1) syndrome, iyo inowedzera zvikuru mukana wako wekuwana gastrinomas. Iyi chirwere chemagene inofamba mumhuri uye inokanganisa vanhu vangangosvika 1 mu30,000.

Zera rine basawo - vanhu vakawanda vanoita Zoster-Ellison syndrome pakati pemakore 30 ne60, neavhareji yemakore iri anenge 50. Nekudaro, kana uine MEN1 syndrome, zviratidzo zvinowanzoonekwa pakutanga, dzimwe nguva mumakore ako makumi maviri kana makumi matatu.

Gender inoratidza muenzaniso mudiki, nevarume vane mukana mukuru wekuwana zviitiko zvisingawanzoitiki. Nekudaro, pakati pevanhu vane MEN1 syndrome, chirwere ichi chinotapura varume nevakadzi zvakafanana. Kuva nenhoroondo yemhuri ye endocrine tumors kana kukuvadzwa kwematumbo usingazivikanwe kunogonawo kuwedzera mukana wako.

Matambudziko anogona kuitika eZoster-Ellison syndrome ndeapi?

Pasina kurapwa kwakakodzera, Zoster-Ellison syndrome inogona kutungamira kumatambudziko akakomba nekuda kwekuvadza kunogara kwenguva refu kubva kune asidhi yakawanda yemudumbu. Mashoko akanaka ndeawo kuti akawanda matambudziko anogona kudzivirirwa nekurapa kwakakodzera.

Kunzwisisa aya matambudziko anogona kuitika kunokubatsira kuziva kuti nei kurapwa kunogara kwenguva refu kuchikosha:

• Peptic ulcers yakakomba inogona kubvaruka kana kukonzera kubuda ropa kunotyisa
• Gastroesophageal reflux disease (GERD) inogona kukuvadza esophagus yako
• Diarrhea inogara kwenguva refu inotungamira pakushomeka kwemvura uye kushomeka kwezvinovaka muviri
• Matambudziko ematumbo kubva pakugadzira tishu
• Kushomeka kwezvinovaka muviri nekuda kwekukanganisa kwemvura
• Matombo emuviri nekuda kwekuchinja muma calcium levels emuviri wako

Mumazuva mashoma, gastrinomas inogona kupararira kune dzimwe nzvimbo dzemuviri wako, kunyanya chiropa chako kana lymph nodes iri pedyo. Nekudaro, aya ma tumors anowanzo kukura zvishoma nezvishoma, uye kuonekwa pakutanga kunowedzera zvikuru tariro yako.

Nekurapa kwakakodzera, vanhu vakawanda vane Zoster-Ellison syndrome vanogona kudzivirira aya matambudziko uye kuchengetedza hupenyu hwakanaka. Kurapwa kunogara kwenguva refu kunobatsira kubata chero matambudziko pakutanga kana ari kurapika zvakanyanya.

Zoster-Ellison syndrome inoongororwa sei?

Kuongorora Zoster-Ellison syndrome kunosanganisira nhanho dzakawanda nekuti zviratidzo zvaro zvinogona kutevedzera mamwe mamiriro ekugaya chikafu. Chiremba wako anotanga nekuteerera zviratidzo zvako uye kukuongorora, ipapo anorayira bvunzo chaiyo kuti aone chirwere chacho.

Bvunzo huru yekuongorora inoyeresa mazinga e gastrin muropa rako. Kana gastrin yako yakakwira zvakanyanya, kunyanya kana yakabatana nekugadzira asidhi yakawanda yemudumbu, izvi zvinoratidza zvakasimba Zoster-Ellison syndrome.

Chiremba wako anogona kuita bvunzo yekukurudzira secretin, kwaanokupa hormone inonzi secretin uye ipapo anoyeresa kuti mazinga ako e gastrin anopindura sei. Muvanhu vane Zoster-Ellison syndrome, mazinga e gastrin anowedzera mushure me secretin, izvo zviri zvakapesana nezvinoitika kune vanhu vane hutano.

Kuongororwa kwemafirimu kunobatsira kuwana gastrinomas mumuviri wako. Izvi zvinogona kusanganisira CT scans, MRI scans, kana bvunzo dzakasarudzika senge somatostatin receptor scintigraphy, iyo inogona kuona ma tumors anogadzira hormone kunyangwe ari madiki zvikuru.

Chiremba wako anogonawo kuita endoscopy kuti aone zvakananga mudumbu rako neatumbo ako maduku, achiongorora kukuvadzwa kwematumbo uye kutora zvikamu zve tishu kana zvichidiwa. Nzira iyi yakakwana inoita kuti uve nechokwadi chekuongororwa kwakanyatsojeka uye inobatsira kuronga kurapa kwako.

Kurapa kweZoster-Ellison syndrome chii?

Kurapa kweZoster-Ellison syndrome kunotarisa pane zvinangwa zviviri zvikuru: kudzora kugadzirwa kwe asidhi yemudumbu uye kugadzirisa gastrinomas pachayo. Vanhu vakawanda vanopindura zvakanaka pakurapa uye vanogona kurarama hupenyu hunowanzoitika, hunofadza.

Mutsara wekutanga wekurapa unosanganisira mishonga inonzi proton pump inhibitors (PPIs), iyo inoderedza zvakanyanya kugadzirwa kwe asidhi yemudumbu. PPIs dzakajairwa dzinosanganisira omeprazole, lansoprazole, uye pantoprazole, uye dzinoshanda zvikuru pakurapa kukuvadzwa kwematumbo uye kudzivirira itsva.

Chiremba wako anogona kutanga kukupa huwandu hwakawanda hwe PPIs kupfuura iyo inowanzo shandiswa kune heartburn yakajairwa. Usazvidya mwoyo - aya mishonga yakachengeteka kushandiswa kwenguva refu kana ichiongororwa zvakanaka, uye vanhu vakawanda vanoitora kwemakore vasina matambudziko.

Kuopereta kunogona kukurudzirwa kana gastrinomas yako ichigona kubviswa zvakanaka. Izvi zvinowanzoitika kana uine tumor imwe chete, iri munzvimbo yakanaka. Nekudaro, kuopereta hakusi nguva dzose kunogona kana kudiwa, kunyanya kana uine ma tumors maduku akawanda kana ari munzvimbo dzakaoma kusvika kwazviri.

Kune gastrinomas dzapararira kana dzisingagone kubviswa nekuopereta, chiremba wako anogona kukurudzira kurapa senge chemotherapy, mishonga inorwisa ma tumors, kana nzira dzekudzivirira ropa kuti risapinda muma tumors. Aya maitiro anogona kubatsira kudzora kukura kwe tumor uye kutungamira zviratidzo zvako zvakanaka.

Nzira yekutungamira sei Zoster-Ellison syndrome pamba?

Kunyangwe kurapwa kwemishonga kuchikosha, kune zvinhu zvakawanda zvaunogona kuita pamba kuti ubatsire kutungamira zviratidzo zvako uye kutsigira hutano hwako hwese. Aya marongero anoshanda zvakanaka kana akabatana nemishonga yako yakapihwa.

Kutora mishonga yako nguva dzose ndiyo nhanho inokosha yaunogona kutora. Gadzira maitiro ekutora PPIs yako, zviri nani panguva imwe chete zuva rega rega uye usati wadya kuti uve nemigumisiro yakanaka.

Cherechedza zvokudya zvinoita sekuipa zviratidzo zvako uye funga kuchengeta bhuku rezvokudya. Kunyangwe kuchinja kwezvokudya kuchigona kurapa Zoster-Ellison syndrome, kudzivisa zvokudya zvinokonzera zviratidzo senge zvinonhuwira, zvakasviba, kana mafuta zvinogona kukubatsira kunzwa zvakanaka.

Kudya zviduku, zvokudya zvakawanda kunogona kuderedza mutoro pamatumbo ako. Edza kudya maawa ose 3-4 panzvimbo yekudya zvokudya zvitatu zvikuru, uye usavata nekukurumidza mushure mekudya.

Gara wakanyorova, kunyanya kana uri kuita diarrhea, uye funga kukurukura nezve zvinowedzerwa nechikura wako kana usina kunwa zvinovaka muviri zvakanaka. Kuita zvemitambo zvinyoro uye nzira dzekudzora kushushikana kunogonawo kutsigira hutano hwako hwese hwematumbo.

Unofanira kugadzirira sei kuenda kuchiremba?

Kugadzirira kuenda kuchiremba kunobatsira kuve nechokwadi chekuti unowana zvakawanda kubva panguva yako nehutano hwako. Kuuya wakagadzirira ruzivo nemibvunzo kunoita kuti shanyo ive yakabudirira kwauri vaviri.

Nyora zviratidzo zvako zvese, kusanganisira apo zvakatanga, kazhinji zvinoitika, uye zvinogadzira zvakanaka kana zvakaipa. Iva wakajeka nezve nzvimbo dzekurwadziwa, nguva yezviratidzo zvine chekuita nezvokudya, uye chero kuchinja mumaitiro ako emudumbu.

Uya ne rondedzero yakazara yemishonga yese yaunotora, kusanganisira mishonga yekutengesa, zvinowedzerwa, uye mishonga yemiti. Unganidzawo chero rekodhi dzehutano, kunyanya kana wakambonzwa nematambudziko emudumbu kana kuongororwa kwemafirimu.

Gadzira rondedzero yemibvunzo nezve mamiriro ako, nzira dzekurapa, uye zvaunofanira kutarisira. Usazengurire kubvunza nezve migumisiro yemishonga, kuchinja mararamiro, kana kuti ungaronga rini shanyo dzekutevera.

Funga kuuya neshamwari yakavimbika kana nhengo yemhuri kuti ikubatsire kuyeuka ruzivo rwakakosha rwakakurukurwa panguva yekushanya. Kuva nekutsigira kunogonawo kukubatsira kunzwa wakasununguka kubvunza mibvunzo kana kutaura zvinokunetsa.

Chii chinonyanya kukosha nezve Zoster-Ellison syndrome?

Zoster-Ellison syndrome chirwere chinogona kutungamirwa kana chakaongororwa zvakanaka uye kurapwa. Kunyangwe iri isingawanzoitika uye inogona kukonzera zviratidzo zvisingafadzi, vanhu vakawanda vane chirwere ichi vanogona kuwana kudzora kwakanaka kwezviratidzo nekurapa kwakakodzera.

Chinhu chakakosha chokuyeuka ndechekuti kurapa kwakakodzera kuripo, uye kuongororwa pakutanga kunotungamira kumigumisiro iri nani. Nekurapa kwakakodzera kwemishonga, vanhu vakawanda vanowana zororo rakakura kubva muzviratidzo zvavo uye vanogona kudzoka kumabasa avo enguva dzose.

Kushanda pedyo nesangano rehutano hwako, kugara uchitsigira mishonga yako, uye kuenda kune zvekutevera nguva dzose ndizvo zvinokosha pakutungamira chirwere ichi zvakanaka. Vanhu vakawanda vane Zoster-Ellison syndrome vanorarama hupenyu hwazvo hwese, hwakanaka nekurapa kwakakodzera.

Kana uri kuita zviratidzo zvemudumbu zvinogara kwenguva refu, usazengurire kutsvaka kuongororwa kwechiremba. Kuonekwa pakutanga nekurapa kunogona kudzivirira matambudziko uye kukubatsira kunzwa zvakanaka nekukurumidza.

Mibvunzo inowanzo bvunzwa nezve Zoster-Ellison syndrome

Zoster-Ellison syndrome inogona kurapika zvachose here?

Kunyangwe pasina mushonga wakajairika, vanhu vakawanda vanowana kudzora kwenguva refu kwezviratidzo zvavo nekurapa kwakakodzera. Kana gastrinomas ichigona kubviswa zvachose nekuopereta, vamwe vanhu vanogona kurapika. Nekudaro, kunyangwe kurapika kuchigona kuitika, vanhu vakawanda vanorarama hupenyu hunowanzoitika nekudzora kwakanaka kwezviratidzo kuburikidza nemishonga.

Zoster-Ellison syndrome inogona kuwanikwa here?

Anenge 25% ezviitiko zvine chekuita nechirwere chinogona kuwanikwa chinonzi MEN1 syndrome, chinogona kupfuudzwa mumhuri. Nekudaro, akawanda ezviitiko (anenge 75%) anoitika yoga pasina nhoroondo yemhuri. Kana uine nhoroondo yemhuri ye endocrine tumors, mazano emagene anogona kubatsira.

Kwenguva yakareba ndinofanira kutora mishonga yeZoster-Ellison syndrome here?

Vanhu vakawanda vanoda kutora mishonga inoderedza asidhi kwenguva refu, kazhinji kweupenyu hwese, kudzivirira kukuvadzwa kwematumbo uye kutungamira zviratidzo. Nekudaro, izvi zvinosiyana zvichienderana nemamiriro ako chaiwo uye kana gastrinomas yako ichigona kubviswa nekuopereta. Chiremba wako acashanda newe kuti aone chirongwa chakanaka chekurapa kwenguva refu.

Kuchinja kwezvokudya kunogona kubatsira kutungamira Zoster-Ellison syndrome here?

Kunyangwe kuchinja kwezvokudya yoga kuchigona kurapa Zoster-Ellison syndrome, kunogona kukubatsira kunzwa zvakanaka pamwe chete nekurapa kwako kwemishonga. Kudzivisa zvokudya zvinonhuwira, zvakasviba, kana mafuta uye kudya zviduku, zvokudya zvakawanda zvinogona kuderedza zviratidzo. Nekudaro, mishonga inoramba iri kurapwa kukuru.

Chii chinotarisirwa kune vanhu vane Zoster-Ellison syndrome?

Zvinotarisirwa zvakanyanya zvakanaka nekurapa kwakakodzera. Vanhu vakawanda vanowana kudzora kwakanaka kwezviratidzo uye vanogona kuchengetedza hupenyu hwavo hwakanaka. Kunyangwe gastrinomas ichigona kubviswa zvachose, hunhu hwekukura zvishoma nezvishoma hwe aya ma tumors uye mishonga inoshanda zvinoreva kuti vanhu vakawanda vanorarama hupenyu hwavo hwese nekudzora kwakanaka kwezviratidzo.