Chii chinonzi Abacavir neLamivudine: Zvavanoshandiswa, Mishonga, Matambudziko, nezvimwe

Abacavir ne lamivudine imishonga inosanganisa HIV inobatsira kudzora hutachiona mumuviri wako. Mushonga uyu unoda kunyorerwa chiremba une mishonga miviri ine simba inorwisa hutachiona inoshanda pamwechete kuti ideredze kugona kweHIV kuzviparadzanisa nekupararira mumuviri wako.

Ungangoziva mushonga uyu nemazita awo emhando seEpzicom kana Kivexa. Chikamu chechirongwa chekurapa chinogona kukubatsira kurarama hupenyu hune hutano, hurefu neHIV kana uchitora nguva dzose sezvakanyorwa nachiremba wako.

Chii chinonzi Abacavir neLamivudine?

Abacavir ne lamivudine itafura inosanganisa mishonga inosanganisa madosi akagadziriswa ine mishonga miviri yakasiyana yeHIV mupiritsi rimwe. Zvese zvinosanganiswa zvinobva kuboka remishonga inonzi nucleoside reverse transcriptase inhibitors, iyo inoshanda nekudzivirira HIV kubva kuzvinyora mukati memaseru ako.

Iyi musanganiswa inoita kuti zvive nyore kwauri kutora kurapwa kwako kweHIV sezvo iwe uchitora mishonga miviri mune imwechete dose. Mushonga uyu unouya setafura yaunomedza yese, uye yakagadzirirwa kuve chikamu chekurapa kwakazara kweHIV pamwe chete nemimwe mishonga inorwisa hutachiona.

Chiremba wako achanyora mushonga uyu sechikamu cheizvo zvinonzi highly active antiretroviral therapy kana HAART. Iyi nzira inoshandisa mishonga yakawanda yeHIV pamwechete kugadzira dziviriro ine simba kurwisa hutachiona mumuviri wako.

Chii chinonzi Abacavir neLamivudine chinoshandiswa?

Mushonga uyu unoshandiswa kunyanya kurapa HIV-1 infection muvanhu vakuru nevana vanorema angangoita makirogiramu makumi maviri nemashanu (anenge mapaundi makumi mashanu nemashanu). Inoshanda sechikamu chekurapa kwemusanganiswa kubatsira kuderedza huwandu hweHIV muropa rako kusvika kumazinga asingawanikwe.

Chinangwa chikuru ndechekubatsira immune system yako kupora uye kuramba yakasimba uchidzivirira HIV kubva pakuenda kuAIDS. Kana ichishandiswa nemazvo nemimwe mishonga yeHIV, iyi musanganiswa inogona kukubatsira kuchengetedza hupenyu hwakajairika uye kudzivirira kuparadzirwa kwehutachiona kune vamwe.

Mupi wehutano hwako anogona kukurudzira musanganiswa uyu kana uri kutanga kurapwa kweHIV kekutanga kana uchida kuchinja kubva kune imwe nzira yekurapa. Zvakakosha kunzwisisa kuti mushonga uyu unorapa HIV asi haupore zvachose.

Mabasa eAbacavir neLamivudine Sei?

Mushonga uyu unoshanda nekukanganisa kugona kweHIV kuzvibereka mukati memaseru ako. Zvese abacavir ne lamivudine zvinovharisa enzyme inonzi reverse transcriptase, iyo HIV inoda kukopa zvinhu zvayo zvemajini uye kugadzira zvitsva zvevirusi.

Funga nezvazvo sekaisa wrench mumagetsi emuchina wekopa weHIV. Kana virusi ichiedza kuwanda, mishonga iyi inoidzivirira kubva kupedzisa maitiro acho zvinobudirira. Izvi zvinobatsira kuderedza huwandu hwevirusi muropa rako nekufamba kwenguva.

Mushonga uyu unoonekwa seune simba zvine mwero kana ukasanganiswa nemimwe mishonga yeHIV. Kunyangwe ichishanda, inoshanda zvakanyanya sechikamu chekurapa kwemishonga mitatu panzvimbo yekushandiswa yega, ndosaka chiremba wako achanyora mimwe mishonga yeHIV pamwe chete nayo.

Ndinofanira Kutora Sei Abacavir neLamivudine?

Unofanira kutora mushonga uyu sezvinorayirwa nachiremba wako, kazhinji kamwe pazuva uine kana pasina chikafu. Piritsi rinogona kutorwa nemvura, mukaka, kana muto, uye haufanirwe kunetseka nezvekuisa nguva yacho nezvikafu sezvo chikafu chisinganyanyi kukanganisa maitiro emuviri wako anotora mushonga.

Edza kutora chiyero chako panguva imwe chete zuva rega rega kuti ubatsire kuchengetedza mazinga emushonga mumuviri wako. Unogona kumisa alarm yezuva nezuva kana kushandisa murongi wepiritsi kuti akubatsire kuyeuka, sezvo kusavapo kwemadosi kunogona kubvumira HIV kuti ive isingadzivirirwe kurapwa.

Medza piritsi rose panzvimbo yekuripwanya, kutsenga, kana kuripwanya. Kana uine dambudziko rekumedza mapiritsi, taura nemuongorori wako wemishonga nezve nzira dzinogona kubatsira, asi usachinje chimiro chepiritsi pasina gwara.

Usati watanga mushonga uyu, chiremba wako achakuedza kuti uone chiratidzo chemajini chinonzi HLA-B*5701. Muedzo uyu wakakosha nekuti vanhu vane shanduko iyi yemajini vane njodzi yakakura yekuwana mhinduro dzakakomba dzekurwara kune abacavir.

Ndinofanira Kutora Abacavir neLamivudine Kwenguva Yakareba Sei?

Unofanira kutora mushonga uyu kweupenyu hwako hwese sechikamu chekurapa kwako HIV kuri kuenderera mberi. Kurapa HIV ibasa renguva refu rinoda mushonga wezuva nezuva kuti utadzise hutachiona uye kuchengetedza immune system yako iine hutano.

Vanhu vazhinji vanotanga kuona kuvandudzwa muviral load yavo mukati mevhiki 2-8 kubva pakutanga kurapwa, nekuderedzwa kukuru kunowanzoitika mukati memwedzi 3-6. Chiremba wako achatarisa kufambira mberi kwako kuburikidza nemiedzo yeropa yenguva dzose kuti ave nechokwadi chekuti mushonga uri kushanda nemazvo.

Usambomira kutora mushonga uyu usati wataura nemupi wehutano wako kutanga, kunyangwe ukanzwa zvakanaka zvachose. Kumisa kurapwa kweHIV kunogona kukonzera hutachiona kuti huwedzere nekukurumidza uye hunogona kukudziridza kuramba mishonga, zvichiita kuti kurapwa kwemunguva yemberi kuve kwakaoma.

Ndezvipi Zvakaipa ZveAbacavir neLamivudine?

Vanhu vazhinji vanotsungirira mushonga uyu zvakanaka, asi semishonga yese, inogona kukonzera mhedzisiro. Mhedzisiro yakajairika inowanzoita nyoro uye inowanzoita nani muviri wako paunojaira kurapwa mumavhiki mashoma ekutanga.

Heano mhedzisiro yakajairika yaungasangana nayo:

• Kutemwa nemusoro uye kuneta
• Nausea uye dumbu rinogumbuka
• Dhiria kana zvigaro zvakasununguka
• Kutadza kurara kana kurota zvakajeka
• Dizziness kana lightheadedness
• Mhino yakavharika kana inoyerera

Izvi zvinowanzoitika mhedzisiro zvinowanzoita zvishoma sezvo muviri wako uchijaira mushonga. Kana vakapfuurira kana kukanganisa mabasa ako ezuva nezuva, mupi wako wehutano anogona kukurudzira nzira dzekuvagadzirisa.

Zvisinei, kune mamwe matambudziko akakomba anoda kutariswa kwekurapa nekukurumidza, kunyangwe asiri akajairika:

• Kutambudzika kwakanyanya kwemuviri (hypersensitivity syndrome)
• Lactic acidosis (kuwanda kwe lactic acid muropa)
• Matambudziko akakomba echiropa
• Kuwedzera kwehepatitis B (kana uine co-infection iyi)

Hypersensitivity reaction ku abacavir ndiyo inonyanya kukonzeresa matambudziko akakomba. Inogona kukonzera fivha, rash, kuneta kwakanyanya, kurwadziwa mudumbu, uye zviratidzo zvakaita sefuruwenza. Kana uine zviratidzo izvi, kunyanya mukati memavhiki matanhatu ekutanga ekurapa, taura nachiremba wako nekukurumidza uye usambofa wakatora mushonga zvakare.

Ndiani Asingafaniri Kutora Abacavir uye Lamivudine?

Haufaniri kutora mushonga uyu kana uine allergic ku abacavir, lamivudine, kana zvimwe zvinosanganiswa mutablet. Uyezve, kana ukaedzwa ukaona kuti une HLA-B*5701 genetic marker, chiremba wako achasarudza imwe nzira yekurapa HIV kudzivirira njodzi yekutambudzika kwakanyanya kwemuviri.

Vanhu vane chirwere chechiropa chakati wandei vanogona kuda madosi akasiyana kana mamwe mishonga. Murapi wako achatarisa kushanda kwechiropa chako usati watanga kurapwa uye achachitarisa nguva dzose paunenge uchitora mushonga.

Kana uine matambudziko eitsvo, chiremba wako angangoda kugadzirisa dose yako kana kufunga nezve mamwe marapirwo. Zvese zvikamu zvekurapa uku zvinogadziriswa kuburikidza neitsvo dzako, saka kushanda kweitsvo kwakakanganiswa kunogona kukanganisa mashandiro emushonga mumuviri wako.

Vakadzi vane pamuviri vanogona kutora mushonga uyu, asi kutariswa kwepedyo kwakakosha. Kana uri kuronga kuva nepamuviri kana kuona kuti une pamuviri paunenge uchitora mushonga uyu, kurukura njodzi nemabhenefiti nemurapi wako nekukurumidza.

Mazita eAbacavir uye Lamivudine Brand Names

Mazita anozivikanwa emishonga iyi yakasanganiswa ndiEpzicom muUnited States neKivexa mune dzimwe nyika. Zvose zvine huwandu hwakafanana hwezvinhu zvinoshanda: 600 mg yeabacavir uye 300 mg ye lamivudine patafura imwe neimwe.

Mishonga yakajairika inogonawo kuwanikwa mune dzimwe nzvimbo, iyo ine zvinhu zvakafanana zvinoshanda asi inogona kunge iine zvinhu zvakasiyana zvisingashandi kana chitarisiko. Murapi wako wemishonga anogona kukubatsira kuziva kana uri kuwana zita remhando kana vhezheni yakajairika.

Nguva dzose taura nemupi wako wehutano usati wachinja pakati pemhando yezita uye vhezheni yakajairika, sezvo vachida kuona kuenderana mukurapa kwako.

Abacavir neLamivudine Zvimwe Zvinhu

Mamwe makomisheni emishonga yeHIV anogona kushanda sezvimwe kana iyi musanganiswa usingakukodzere. Chiremba wako angangofunga emtricitabine uye tenofovir (Truvada), emtricitabine uye tenofovir alafenamide (Descovy), kana mamwe makomisheni e nucleoside reverse transcriptase inhibitor.

Kune vanhu vasingakwanise kutora abacavir nekuda kweHLA-B*5701 positivity, zvimwe zvinowanzo sanganisira tenofovir-based combinations. Izvi zvinoshanda zvakafanana nekudzivisa HIV replication asi zvinoshandisa nzira dzakasiyana uye zvine mativi akasiyana ekushanda.

Mupi wako wehutano achafunga nezvezvinhu zvakaita sebasa remapapu ako, hutano hwemapfupa, mamwe mamiriro ehutano, uye mikana yekudyidzana kwemishonga pakusarudza imwe nzira yakanakisa yemamiriro ako chaiwo.

Ko Abacavir neLamivudine Zviri Nani Pane Tenofovir neEmtricitabine?

Zvese zvinosanganiswa zvinoshanda zvakanyanya kurapa HIV, asi hapana imwe iri yakanaka kupfuura imwe. Sarudzo inoenderana nehutano hwako hwega, zvinhu zvemajini, uye kuti unotsungirira sei mushonga wega wega.

Abacavir ne lamivudine zvingasarudzwa kana uine matambudziko eitsvo kana matambudziko ekuwanda kwemapfupa, nekuti tenofovir dzimwe nguva inogona kukanganisa nzvimbo idzi. Zvisinei, tenofovir mibatanidzwa inogona kusarudzwa kana ukaedzwa uine HLA-B*5701 kana uine mamwe mamiriro echiropa.

Chiremba wako achatarisa nhoroondo yako yese yezvokurapa, mhedzisiro yelaboratory, uye zvaunofarira iwe pachako paunenge uchisarudza kuti ndeipi mhando inokushandira zvakanaka. Zvese zvingasarudzwa zvine marekodhi akaratidzwa mumayunivhesiti ekiriniki uye kushandiswa kwenyika chaiyo.

Mibvunzo Inowanzo Bvunzwa Nezve Abacavir ne Lamivudine

Abacavir ne Lamivudine Zvakachengeteka Kune Vanhu vane Hepatitis B here?

Mushonga uyu unogona kushandiswa kune vanhu vane hepatitis B, asi zvinoda kunyatsoongororwa. Lamivudine ine basa rinopesana nehutachiona hwehepatitis B, saka kana uine HIV nehepatitis B, kumisa mushonga uyu kunogona kukonzera kuti hepatitis B yako ipararire zvakanyanya.

Chiremba wako achanyatsoongorora basa rechiropa chako uye anogona kuraira imwe kurapwa kwehepatitis B kana zvichidikanwa. Usambomira kutora mushonga uyu usina kutarisirwa nachiremba kana uine hepatitis B co-infection.

Ndingaita Sei Kana Ndikatora Abacavir ne Lamivudine zvakawandisa netsaona?

Kana netsaona ukatora zvakawanda kupfuura chiyero chako chakatemwa, taura nemupi wako wehutano kana nzvimbo yekudzora chepfu nekukasira. Kunyange zvazvo zviratidzo zvakakomba zvekuwandisa zvisingawanzoitiki nemushonga uyu, kutora zvakawanda kunogona kuwedzera njodzi yako yemigumisiro.

Usaedze kutsiva chiyero chakawedzerwa nekusvetuka chiyero chako chinotevera chakarongeka. Pane kudaro, ramba uchienderera mberi nechiyero chako chemazuva ese kunze kwekunge chiremba wako achikuraira zvimwe.

Ndingaita Sei Kana Ndikarasikirwa neDose yeAbacavir ne Lamivudine?

Kana ukakanganwa chiyero, chitore paunorangarira, kunze kwekunge yava nguva yechiyero chako chinotevera chakarongeka. Muchiitiko ichocho, svetuka chiyero chakarasika uye tora chiyero chako chinotevera panguva yakajairika.

Usambotora zvikamu zviviri panguva imwe chete kuti ugadzirise chikamu chawakakanganwa. Kana uchikanganwa zvikamu kazhinji, taura nachiremba wako wehutano nezve nzira dzekukubatsira kuyeuka, sekugadza maalarm emafoni kana kushandisa vagadziri vemishonga.

Ndingamira Rini Kutora Abacavir neLamivudine?

Haufanire kumira kutora mushonga uyu usati wataurirana nachiremba wako wehutano kutanga. Kurapa HIV kunogara kwenguva refu, uye kumisa mushonga kunogona kukonzera kuti hutachiona huwedzere nekukurumidza uye hunogona kukudziridza kuramba.

Chiremba wako angachinja mushonga wako kana uine mhedzisiro kana kana kurapwa kutsva kwawanikwa, asi sarudzo iyi inofanirwa kugara ichiitwa pamwe chete nekutarisa kwekurapa.

Ndinganwa Doro Here Ndichitora Abacavir neLamivudine?

Kunwa doro zvine mwero kunogamuchirwa zvakajairika uchitora mushonga uyu, asi kunwa zvakanyanya kunogona kuwedzera njodzi yako yematambudziko echiropa uye kunogona kukanganisa kushanda kwemushonga wako weHIV.

Kana uine chirwere chechiropa kana nhoroondo yematambudziko edoro, taura nezvekushandiswa kwedoro nachiremba wako wehutano. Vanogona kupa gwara rakagadzirirwa zvinoenderana nemamiriro ako ehutano.