Chii chinonzi Abaloparatide: Zvayakashandiswa, Mishonga, Zvazvinokonzera uye Zvimwe Zvakawanda

Abaloparatide mushonga unopiwa nachiremba unobatsira kuvaka mapfupa akasimba muvanhu vane osteoporosis yakakomba. Inoshanda nekutevedzera mahomoni echisikigo mumuviri wako anokurudzira kuumbwa kwemapfupa, zvichiita kuti ive inokosha kune avo vari panjodzi huru yekutyoka.

Mushonga uyu unomiririra nzira itsva yekurapa osteoporosis. Kusiyana nemimwe mishonga yemapfupa inonyanya kudzivirira kurasikirwa kwemapfupa, abaloparatide inobatsira muviri wako kugadzira nyowani mapfupa matishu, izvo zvinogona kukurudzira kana wanga uchibata nemapfupa anopera simba.

Chii chinonzi Abaloparatide?

Abaloparatide ishanduro yekugadzirwa ye parathyroid hormone-related protein iyo muviri wako unogadzira pachisikigo. Iyo ndeyeboka remishonga inonzi bone anabolic agents, zvinoreva kuti inobatsira kuvaka mapfupa matsva panzvimbo yekungodzivirira kurasikirwa kwemapfupa.

Mushonga uyu unouya sepeni yakazadzwa kare yaunojowa pasi peganda rako kamwe chete pazuva. Yakagadzirirwa zvakananga vanhu vane osteoporosis vane njodzi huru yekutyoka, kunyanya vakadzi vakapfuura menopause uye varume vane kurasikirwa kwemapfupa kwakanyanya.

Chiremba wako angakurudzira abaloparatide kana mamwe marapirwo eosteoporosis asina kushanda zvakanaka kana njodzi yako yekutyoka yakanyanya. Inoonekwa semushonga wakasimba unogona kuita mutsauko unokosha musimba remapfupa nekufamba kwenguva.

Chii chinonzi Abaloparatide chinoshandiswa?

Abaloparatide inonyanya kushandiswa kurapa osteoporosis muvakadzi vakapfuura menopause vane njodzi huru yekutyoka. Inobvumidzwawo kurapa osteoporosis muvarume vane kurasikirwa kwemapfupa kwakanyanya avo vari panjodzi yakawedzerwa yekutyoka.

Chiremba wako angakupa mushonga uyu kana iwe wakambotyoka nekuda kweosteoporosis, uine zvibodzwa zvakaderera kwazvo zvemapfupa, kana usina kupindura zvakanaka kune mamwe marapirwo eosteoporosis. Zvinonyanya kubatsira vanhu vane mapfupa avo akava asina simba zvakanyanya.

Mushonga uyu wakagadzirirwa zvakananga nyaya dzakakomba dze osteoporosis. Kazhinji haisi iyo yekutanga sarudzo yekurapa asi inochengeterwa mamiriro ezvinhu apo kuvaka mapfupa matsva nekukurumidza kwakakosha kudzivirira kuputsika kwakakomba.

Abaloparatide Inoshanda Sei?

Abaloparatide inoshanda nekumutsa maseru mumapfupa ako anonzi osteoblasts, ayo ane basa rekuvaka nyama itsva yemapfupa. Inotevedzera chiito cheparathyroid hormone-related protein, chinhu chechisikigo chinogadzirwa nemuviri wako kuti utarise kuumbwa kwemapfupa.

Paunobaya abaloparatide, inoratidza maseru ako ekuvaka mapfupa kuti ashande zvakanyanya. Iyi nzira inobatsira kugadzira matrix itsva yemapfupa uye inowedzera kuwanda kwemapfupa nekufamba kwenguva. Fungidzira sekupa mapfupa ako kusimudzira zuva nezuva kuti azvivakezve akasimba.

Mushonga uyu unoonekwa seune simba zvakanyanya maererano nemhedzisiro yekuvaka mapfupa. Kusiyana nemimwe mishonga ye osteoporosis iyo inonyanya kunonotsa kurasikirwa kwemapfupa, abaloparatide inoshingairira kumutsa kukura kwemapfupa matsva, izvo zvinogona kutungamira mukuvandudzwa kunokosha musimba remapfupa mukati memwedzi yekutanga kurapwa.

Ndingatora Sei Abaloparatide?

Iwe uchabaya abaloparatide kamwe chete pazuva uchishandisa mudziyo wepeni wakazadzwa kare, kazhinji muchidya chako kana dumbu. Kubaya kunoenda pasi peganda rako (subcutaneous), kwete mumhasuru, uye iwe uchachinja nzvimbo dzekubaya kudzivirira kutsamwa.

Tora jekiseni rako panguva imwe chete zuva rega rega kuti uchengetedze mazinga akagadzikana mumuviri wako. Vanhu vazhinji vanozviwana zvichibatsira kuzvibaya mangwanani, asi unogona kusarudza chero nguva inoshanda zvakanyanya pachirongwa chako.

Haufaniri kutora mushonga uyu nechikafu, asi zvakakosha kuti urambe wakanyatsogadzirwa nemvura uye uchengetedze calcium yakakwana uye vitamini D paunenge uchishandisa abaloparatide. Chiremba wako anogona kukurudzira calcium uye vitamini D zvinowedzera kutsigira maitiro ekuvaka mapfupa.

Chengetai mapeni emishonga yenyu mufiriji uye muvabvumire kuti vasvike pakupisa kwemumba vasati vabaya. Musambofa makazunza peni, uye nguva dzose shandisai tsono itsva pakuita jekiseni rega rega kudzivirira hutachiona uye kuona kuti mishonga inosvika zvakanaka.

Ndingatora Abaloparatide Kwenguva Yakareba Sei?

Abaloparatide inowanzo nyorerwa kwemwedzi makumi maviri nemana (makore maviri) muhupenyu hwenyu hwose. Muganho uyu uripo nekuti ruzivo rwekuchengeteka kwenguva refu kupfuura makore maviri rwakatemerwa, uye mhedzisiro yekuvaka mapfupa yemushonga inonyanya kuoneka munguva iyi.

Chiremba wenyu achatarisa kufambira mberi kwenyu kuburikidza nekutarisa kuwanda kwemapfupa uye mamwe maedzo panguva yekurapa. Vanhu vazhinji vanoona kuvandudzwa kunobatsira mukuwanda kwemapfupa mukati memwedzi mitanhatu kusvika gumi nemiviri yekutanga mushonga.

Mushure mekupedza kosi yenyu ye abaloparatide, chiremba wenyu anogona kukurudzira kuchinjira kumumwe mushonga we osteoporosis kuchengetedza simba remapfupa ramakawana. Kurapa uku kunotevera kwakakosha nekuti mhedzisiro yekuvaka mapfupa ye abaloparatide inogona kudzikira kana isina kuteverwa nekurapa kunochengetedza mapfupa.

Ndezvipi Zvipingamupinyi zveAbaloparatide?

Semishonga yose, abaloparatide inogona kukonzera zvipingamupinyi, kunyange vanhu vazhinji vachizvigamuchira zvakanaka. Zvipingamupinyi zvakajairika zvinowanzoita zvinyoro uye zvinowanzoita nani muviri wenyu paunojaira mushonga.

Heano zvipingamupinyi zvaungasangana nazvo, uye zvinobatsira kuziva zvekutarisira kuitira kuti muzvigadzirise zvakanaka:

• Kushatirwa panzvimbo yekubaya - Kutsvukira, kuzvimba, kana kurwadziwa kudiki panobayirwa, kazhinji kwenguva pfupi
• Muviri kusanzwa zvakanaka (Nausea) - Kazhinji kudiki uye kunogona kuvandudzika nekufamba kwenguva
• Kutemwa nemusoro - Kazhinji kunogona kudzoreka nemishonga yekurwadziwa inowanikwa pasina chiremba
• Kutadza kufema (Dizziness) - Kunyanya kana uchimuka nekukurumidza
• Kuneta - Kunzwa kuneta kupfuura zvakajairika, kunyanya mumavhiki mashoma ekutanga
• Kurwadziwa mudumbu rekumusoro - Kazhinji kudiki uye kwenguva pfupi

Izvi zvinowanzoitika zvinogumbura zvinowanzoita zvishoma sezvo muviri wako uchigadzirisa kumishonga, uye vanhu vazhinji vanozviona zvichidzoreka zvakakwana kuti vaenderere mberi nekurapwa.

Zvimwe zvinokonzeresa zvakanyanya hazviwanzoitiki asi zvinoda kutariswa kwekurapa nekukurumidza. Izvi zvinosanganisira maitiro akakomba ekuita allergic, muviri usinganzwe zvakanaka unogara uine kurutsa, kana kurwadziwa kwemapfupa kusingajairiki kusingavandudzi.

Vamwe vanhu vanogona kusangana nemazinga akakwira ecalcium muropa ravo, ndosaka chiremba wako achatarisa mazinga ako ecalcium kuburikidza nekuongororwa kweropa nguva dzose. Zviratidzo zvecalcium yakakwira zvinosanganisira nyota yakanyanyisa, kuwanzokanda mvura, kana kuvhiringidzika.

Ndiani Asingafaniri Kutora Abaloparatide?

Abaloparatide haina kukodzera munhu wese, uye kune mamiriro akati wandei akakosha apo mushonga uyu unofanirwa kudziviswa. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa usati wanyora.

Haufanire kutora abaloparatide kana uine nhoroondo yegomarara remapfupa, mamwe magomarara akapararira kumapfupa, kana mazinga akakwira asingatsananguriki e alkaline phosphatase. Mushonga uyu haukurudzirwiwo kana wakambove neradiation therapy inosanganisira mapfupa ako.

Vanhu vane chirwere chakakomba cheitsvo, mazinga akakwira ecalcium muropa ravo, kana nhoroondo yematombo eitsvo vanofanirwa kushandisa mushonga uyu nekuchenjerera kwakanyanya kana kuudzivisa zvachose. Vakadzi vane pamuviri kana vanoyamwisa havafaniri kushandisa abaloparatide, sezvo mhedzisiro yayo pavacheche vari kukura isingazivikanwe.

Kana uine chirwere chePaget chemupfupa, wakambobatwa nemimwe mishonga yemupfupa kwemakore anopfuura 2, kana uine nhoroondo yerwadziwa rwemapfupa risingatsananguriki, chiremba wako achada kuongorora zvakanyatso kana abaloparatide yakakunakira.

Mazita eAbaloparatide Brand

Abaloparatide inowanikwa pasi pezita remhando reTymlos muUnited States. Iri ndiro zita guru remhando raunosangana naro kana chiremba wako akanyora mushonga uyu.

Mushonga uyu unouya sepeni yekuzadza-isina-kuzadzwa inosanganisira zviyero zvakawanda. Peni imwe neimwe yakagadzirirwa nyore kushandisa uye kuyera zvakarurama, zvichiita kuti jekiseni rezuva nezuva rive nyore kubata kune vanhu vazhinji.

Nguva dzose shandisa mhando yakanyorwa nachiremba wako, sezvo mafomu akasiyana anogona kuva nezvinhu zvakasiyana zvishoma kana zvinodiwa zvekuyera.

Zvimwe Zvinhu zveAbaloparatide

Kana abaloparatide isina kukunakira, mishonga yakati wandei yeosteoporosis iripo. Sarudzo inoenderana nemamiriro ako chaiwo, nhoroondo yako yezvokurapa, uye kuti osteoporosis yako yakakomba sei.

Teriparatide imwe mushonga wekuvaka mapfupa unoshanda zvakafanana neabaloparatide asi wave uripo kwenguva refu. Inopiwawo sejekiseni rezuva nezuva uye ine kushanda kwakafanana mukuvaka density yemupfupa.

Kune vanhu vanosarudza mishonga yemuromo, bisphosphonates senge alendronate kana risedronate inogona kubatsira kudzivirira kurasikirwa kwemapfupa, kunyangwe vasiri kuvaka mapfupa matsva seabaloparatide. Izvi zvinowanzo shandiswa sekurapa kwekuchengetedza mushure mekupera kwemushonga wekuvaka mapfupa.

Denosumab ijojo inopiwa mwedzi mitanhatu yega yega iyo inodzivirira kurasikirwa kwemapfupa uye inoderedza njodzi yekutyoka. Zvinonyanya kubatsira kune vanhu vasingakwanise kutsungirira majekiseni ezuva nezuva kana mishonga yemuromo.

Abaloparatide Zviri Nani Pane Teriparatide Here?

Zvese abaloparatide uye teriparatide mishonga inoshanda yekuvaka mapfupa, uye sarudzo pakati pavo inowanzouya pasi pezvinhu zvemunhu mumwe nemumwe uye kuongorora kwachiremba wako kwezvaunoda.

Zvidzidzo zvinoratidza kuti abaloparatide inogona kukonzera kusimudzwa kushoma mumazinga ecalcium yeropa ichienzaniswa ne teriparatide, izvo zvinogona kubatsira kune vamwe vanhu. Mishonga yese ine kushanda kwakafanana mukuvaka kuwanda kwemapfupa uye kuderedza njodzi yekutyoka.

Mhedzisiro yezvinhu zvakafanana pakati pemishonga miviri, nekuti ese ari maviri anokonzera maitiro ekudzivirira jekiseni, kusvotwa, uye dzungu kune vamwe vanhu. Chiremba wako achafunga nezve nhoroondo yako yezvokurapa, mamwe mishonga yaunotora, uye zvaunofarira iwe pachako paunenge uchisarudza pakati pavo.

Mutengo uye inishuwarenzi inogonawo kukanganisa sarudzo, sezvo izvi zvinhu zvinogona kusiyana zvakanyanya pakati pemishonga yakasiyana uye zvirongwa zveinishuwarenzi.

Mibvunzo Inowanzo Bvunzwa Nezve Abaloparatide

Abaloparatide Yakachengeteka Here Kune Vanhu vane Chirwere Chemoyo?

Abaloparatide inowanzoonekwa seyakachengeteka kune vanhu vane chirwere chemoyo, asi chiremba wako achada kuongorora mamiriro ako chaiwo emoyo. Mushonga hauwanzokonzera mhedzisiro yakakosha ine chekuita nemoyo kune vanhu vazhinji.

Zvisinei, kana uine chirwere chemoyo chakakomba kana kutora mishonga yakawanda yemoyo, chiremba wako anogona kuda kukutarisa zvakanyanya paunotanga abaloparatide. Vamwe vanhu vanogona kuona dzungu, izvo zvinogona kukanganisa avo vane mamwe mamiriro emoyo.

Gara uchizivisa chiremba wako nezve mishonga yese yemoyo yaunotora, sezvo vachida kuona kuti hapana kubatana uye kuti mamiriro ako emoyo akagadzikana usati watanga kurapwa uku kwekuvaka mapfupa.

Ndingaita Sei Kana Ndikashandisa Abaloparatide Yakawandisa Netsaona?

Kana ukabaya abaloparatide yakawanda kupfuura yakarairwa netsaona, fonera chiremba wako kana mupi wehutano nekukasira. Kutora yakawanda zvikuru kungakonzera kuwedzera kwe calcium muropa rako, izvo zvinogona kuva zvakakomba.

Tarisa zviratidzo zve calcium yakawanda, kusanganisira nyota yakanyanya, kuenda chimbuzi kakawanda, kusvotwa, kurutsa, kuvharika mudumbu, kana kuvhiringidzika. Kana ukaona chero zviratidzo izvi, tsvaga rubatsiro rwekurapa nekukasira.

Usaedze "kugadzirisa" overdose nekusvetuka madosi emunguva yemberi. Panzvimbo pezvo, tevera gwara rechiremba wako rekuti ungatanga riini chirongwa chako chekushandisa mishonga. Chengeta mapaketi emushonga newe paunotsvaga rubatsiro rwekurapa kuitira kuti vapi vehutano vazive chaizvo zvawakatora uye zvakawanda sei.

Ndingaita Sei Kana Ndakanganwa Dose yeAbaloparatide?

Kana ukakanganwa dose ye abaloparatide, itore paunorangarira zuva rimwe chetero. Kana zvatoita zuva rinotevera, svetuka dose yakakanganwa uye uenderere mberi nechirongwa chako chezuva nezuva zuva rinotevera.

Usambofa wakatora madosi maviri pazuva rimwe chetero kuti ugadzirise dose yakakanganwa, sezvo izvi zvingawedzera njodzi yako yezvinhu zvisingadiwi, kunyanya kuwedzera kwe calcium. Zviri nani kukanganwa dose imwe pane kuwedzera.

Kana uchikanganwa madosi kakawanda, funga kumisa alarm yezuva nezuva kana kushandisa app yekukuyeuchidza mishonga. Kushandisa mishonga zuva nezuva kunobatsira kuchengetedza mazinga akagadzikana emushonga mumuviri wako kuti uwane mhedzisiro yakanaka yekuvaka mapfupa.

Ndingamira Rini Kutora Abaloparatide?

Unofanira kungomira kutora abaloparatide pasi pekutungamirirwa nachiremba wako. Mushonga unowanzo rairwa kwemwedzi inosvika makumi maviri nemana, uye kumira kare zvingareva kuti hauwani mabhenefiti akazara ekuvaka mapfupa.

Chiremba wako achatarisa kufambira mberi kwako kuburikidza nekuongorora kuwanda kwemapfupa uye anogona kuraira kumira kana ukaona zvinhu zvisingadiwi zvakanyanya kana kana kuwanda kwemapfupa ako kwakavandudzika zvakakwana. Zvisinei, chisarudzo ichi chinofanira kugara chichiitwa pamwe chete nemupi wako wehutano.

Kana ukamira kushandisa abaloparatide, chiremba wako anogona kukurudzira kuchinja kune rimwe mushonga we osteoporosis kuti uchengetedze simba remapfupa raunowana. Kurapa uku kunotevera kwakakosha nekuti mabhenefiti e abaloparatide anogona kudzikira pasina kuramba uchishandisa mushonga unochengetedza mapfupa.

Ndingafamba ne Abaloparatide here?

Hongu, unogona kufamba ne abaloparatide, asi zvinoda kuronga nekuti mushonga unofanirwa kuchengetwa mufiriji. Paunenge uchifamba, shandisa cooling pack kana bhegi rine insulation kuti uchengetedze tembiricha yakakodzera.

Pazvifambiso zvepamhepo, takura mushonga wako mumutoro wako wecarry-on pane mutoro wakaongororwa kudzivirira tembiricha yakanyanyisa. Uya netsamba kubva kuchiremba wako ichitsanangura kudiwa kwako mushonga uye zvinhu zvekujekesa.

Kana uri kufamba uchipfuura nenzvimbo dzenguva, edza kuchengetedza chirongwa chako chekushandisa mushonga sezvazvinogona. Ungangoda kugadzirisa zvishoma nezvishoma nguva yako yekujekesa mumazuva mashoma kuti ienderane nenzvimbo yako itsva yenguva uchichengetedza zvikamu anenge maawa makumi maviri nemana akaparadzana.