Chii chinonzi Abciximab: Zvinoshandiswa, Mishonga, Migumisiro Yakaipa uye Zvimwe

Abciximab mushonga une simba unobatsira kudzivirira ropa kuumbana panguva yekuvhiyiwa kwemoyo kwakakomba. Imushonga wakakosha unovhiyiwa nachiremba muzvipatara kana uri kuita mamwe marapirwo emoyo senge angioplasty kana stent placement.

Mishonga iyi inoshanda nekudzivisa maseru madiki eropa anonzi platelets kubva pakunamatirana. Funga nezvazvo sechidzitiro chenguva pfupi chinochengeta ropa rako richiyerera zvakanaka panguva dzakakosha apo kuumbwa kweropa kunogona kuva kwengozi.

Chii chinonzi Abciximab?

Abciximab mushonga unopiwa nachiremba uyo ari muboka rinonzi platelet inhibitors. Ndicho chiremba chinoti "monoclonal antibody" - zvakanyanya protein yakagadzirwa murabhoritari inotarisa zvikamu zvakakosha zvemaseru ako eropa.

Iwe unongogamuchira mushonga uyu muchipatara kuburikidza neIV line. Haisi chinhu chaunotora kumba kana kutora kubva kukiriniki. Chikwata chekurapa chinokutarisa zvakanyatso chenjerera paunogamuchira.

Mishonga iyi ine simba uye inoshanda nekukurumidza kana yapinda muropa rako. Yakagadzirirwa kushandiswa kwenguva pfupi panguva yemaitiro ekurapa akasiyana apo kudzivirira ropa kuumbana kwakakosha zvachose.

Chii chinonzi Abciximab chinoshandiswa?

Vachiremba vanonyanya kushandisa abciximab panguva yekuvhiyiwa kwemoyo kudzivirira ropa rinokuvadza. Inowanzo kupiwa panguva yepercutaneous coronary intervention (PCI) - maitiro ayo vanachiremba vanovhura tsinga dzemoyo dzakavharika.

Mamiriro makuru aunogona kugamuchira abciximab anosanganisira angioplasty, uko vanachiremba vanovhuvhuta bhururu diki kuvhura tsinga dzakavharika, uye stent placement, uko vanoisa machubhu madiki emesh kuchengeta tsinga dzakavhurika. Inoshandiswawo panguva dzemamwe marudzi emoyo catheterization maitiro.

Dzimwe nguva vanachiremba vanoriraira kuvarwere vane nzira dzekukurumidza dzemoyo, kunyanya kana uri panjodzi huru yekuvandudza magwamba. Chiremba wako wemoyo angakurairawo kana uine angina isina kugadzikana - kurwadziwa muchipfuva kunoitika zvisingatarisirwi.

Abciximab Inoshanda Sei?

Abciximab inoshanda nekudzivisa ma receptors akati wandei pa platelets yako anonzi GP IIb/IIIa receptors. Aya ma receptors akaita sema docking stations uko platelets inowanzo batana kuumba magwamba.

Kana abciximab yabatana nema receptors aya, inodzivirira platelets kubva pakubatanidzwa pamwe chete. Izvi zvinonyanya kukosha panguva yenzira dzemoyo nekuti maturusi nemidziyo inoshandiswa dzimwe nguva inogona kukonzera kuumbwa kwemagwamba asingadiwi.

Mishonga iyi inoonekwa seyakasimba kwazvo - ine simba rakawanda kupfuura zvinoderedza ropa zvakajairika zvakaita seaspirin. Inopa dziviriro yakasimba asi yenguva pfupi pamusoro pekuumbwa kwemagwamba, izvo ndizvo chaizvo zvinodiwa panguva yenzira dzine njodzi huru.

Mhedzisiro inotanga mukati memaminitsi mashoma ekutanga infusion yeIV. Kugona kweropa rako kuumbwa magwamba kunoramba kuchideredzwa zvakanyanya kwemaawa akati wandei, kunyangwe mushonga wakamiswa.

Ndingatora Sei Abciximab?

Hautore abciximab iwe pachako - inogara ichipihwa nenyanzvi dzezvekurapa dzakadzidziswa muchipatara. Mushonga unouya kuburikidza neIV line, kazhinji muruoko rwako kana ruoko.

Chikwata chako chekurapa chichatanga ne loading dose, iyo iri huwandu hukuru hwekutanga hunopihwa nekukurumidza. Izvi zvinoteverwa nekuenderera mberi kwe infusion iyo inopa huwandu hudiki kwemaawa akati wandei.

Haufaniri kunetseka nezve zvirambidzo zvekudya usati wagamuchira abciximab. Zvisinei, chiremba wako angakukumbira kuti udzivise mishonga kana zvinowedzera zvinogona kuwedzera njodzi yekubuda ropa.

Vashandi vekuchengeta vachakutarisa zvakanyanya panguva yese yekuita. Vanoongorora zviratidzo zvako zvakakosha nguva dzose uye vanotarisa chero zviratidzo zvekubuda ropa kana dzimwe matambudziko.

Ndingatora Abciximab Kwenguva Yakareba Sei?

Kurapa neAbciximab kunogara kwenguva pfupi, kazhinji kwemaawa 12 kusvika ku24. Kureba chaiko kunoenderana nemaitiro ako chaiwo uye njodzi dzako pachako.

Varwere vazhinji vanogamuchira mushonga kwemaawa anenge 12 mushure mekunge maitiro avo emoyo apedzwa. Mune dzimwe nguva, kunyanya maitiro akaoma, chiremba wako anogona kuwedzera kurapwa kusvika kumaawa 24.

Chikwata chako chekurapa chichasarudza nguva chaiyo zvichienderana nekuti maitiro ako akafamba sei uye mhinduro yemuviri wako. Vachafunga nezvezvinhu zvakaita senjodzi yekubuda ropa uye kuti moyo wako uri kupora sei.

Kana kupinza kwapera, mhedzisiro yemushonga inopera zvishoma nezvishoma mukati mezuva rimwe kana maviri anotevera. Kugona kwako kwemuviri kuita ropa rinobuda kunodzoka, asi izvi zvinoitika zvishoma nezvishoma kuti uve nechokwadi chekuchengeteka kwako.

Ndezvipi Zvakaipa zveAbciximab?

Mhedzisiro yakanyanya yeabciximab kubuda ropa, iyo inogona kubva pakukuvadzwa kudiki kusvika kune kwakakomba. Izvi zvinoitika nekuti mushonga unoderedza nemaune kugona kweropa rako kuita bundu.

Heano mhedzisiro yakajairika yaungasangana nayo:

• Kubuda ropa panzvimbo yeIV kana nzvimbo yekupinza catheter
• Kukuvara nyore paganda rako
• Kusvotwa kana kusagadzikana mudumbu
• Kutemwa nemusoro kana dzungu
• Kurwadziwa kwemumashure, kunyanya panzvimbo yemaitiro
• Kuderera kweropa

Mhedzisiro iyi inowanzo manejwa uye inotariswa zvakanyanya nechikwata chako chehutano. Vazhinji vanogadzirisa vega sezvo mushonga uchibviswa muhurongwa hwako.

Mhedzisiro yakakomba asi isingawanzoitiki inoda kutariswa kwekurapa nekukurumidza:

• Kubuda ropa kwakanyanya kusingamire nekumanikidza
• Ropa mumvura yako kana chigaro
• Kubuda ropa kusinganzwisisike kubva mumagumbeze ako kana mhino
• Kurwadziwa kwakanyanya muchipfuva kana kufema kwemhepo
• Zviratidzo zve stroke sekusagadzikana kamwe kamwe kana kusimba
• Maitiro akakomba ekugadzirisa muviri ane rash kana kuoma kufema

Chikwata chako chekurapa chakadzidziswa kuziva nekukurumidza nekurapa matambudziko aya. Vane mishonga uye maitiro akagadzirira kushandura mhedzisiro yeabciximab kana zvichidikanwa.

Matambudziko asingawanzoitiki asi akakomba anogona kusanganisira kubuda ropa kukuru kwemukati kana thrombocytopenia - kudonha kunotyisa muhuwandu hwemaplatelet. Izvi zvinoitika muvanhu vashoma pane 1% asi zvinoda kupindira nekukurumidza.

Ndiani Asingafaniri Kutora Abciximab?

Abciximab haina kuchengeteka kune munhu wese, kunyanya avo vane mamiriro anowedzera njodzi yekubuda ropa. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati asarudza kana yakakodzera kwauri.

Haufaniri kugamuchira abciximab kana uine kubuda ropa kunoshanda chero kupi zvako mumuviri wako. Izvi zvinosanganisira kubuda ropa kuri pachena senge kubuda ropa mumhino kana kubuda ropa kwakavanzika senge maronda mudumbu.

Vanhu vane mamiriro ekurapa akati wandei vanofanirwa kudzivisa mushonga uyu zvachose:

• Kuvhiyiwa kukuru munguva pfupi yapfuura mukati memavhiki matanhatu apfuura
• Nhoroondo ye sitiroko mukati memakore maviri apfuura
• Kukwira kweropa kwakanyanya kusingadzoreki
• Zvirwere zvinobuda ropa zvinozivikanwa senge hemophilia
• Chirwere chakakomba chechiropa kana itsvo
• Kenza inoshanda ine njodzi yekubuda ropa
• Kukuvara kwemunguva pfupi yapfuura kana kukuvara kwemusoro

Chiremba wako achavawo akangwarira kana uri kutora mamwe mishonga inoderedza ropa. Musanganiswa uyu unogona kuwedzera zvakanyanya njodzi yekubuda ropa kupfuura mazinga akachengeteka.

Vakadzi vane pamuviri havafaniri kugamuchira abciximab kunze kwekunge mabhenefiti achipfuura njodzi. Mushonga uyu unogona kuyambuka placenta uye zvinogona kukanganisa mwana ari kukura.

Zera rega rega harisi rekukodzera, asi vanhu vakuru vangangoda kugadzirisa dosi kana kuongororwa kwakawedzerwa nekuda kwekuwedzera kubuda ropa.

Mazita eAbciximab Brand

Abciximab inonyanya kuzivikanwa nezita rayo remhando ReoPro. Iyi ndiyo yekutanga uye yakanyanya kushandiswa yemushonga muzvipatara.

Kusiyana nemishonga yakawanda, abciximab haina mazita akawanda emhando kana mhando dzakajairika. ReoPro inoramba iri iyo fomu yakajairika inoshandiswa muzvipatara pasi rese.

Paunenge uchikurukura kurapwa kwako navanachiremba, vanogona kureva kwairi nezita ripi zvaro - abciximab kana ReoPro. Mazwi ese ari maviri anoreva mushonga mumwe chete une mhedzisiro yakafanana uye kuyera.

Zvimwe Zvingashandiswa Panzvimbo paAbciximab

Mishonga yakati wandei inogona kupa kudzivirirwa kwakafanana kwegwamba reropa panguva yezvirongwa zvemtima. Chiremba wako angasarudza zvimwe zvingashandiswa zvichienderana nemamiriro ako chaiwo uye njodzi.

Eptifibatide na tirofiban ndizvo zviviri zvingashandiswa zvinoshanda zvakafanana ne abciximab. Ndivo zvakare GP IIb/IIIa receptor blockers asi vane nguva shoma yekushanda.

Vamwe vanachiremba vanosarudza izvi zvimwe zvingashandiswa nekuti mhedzisiro yavo inopera nekukurumidza kana matambudziko ekubuda ropa akaitika. Zvisinei, havangave vaine simba se abciximab yezvirongwa zvine njodzi yakawanda.

Mishonga mimwe yekutapudza ropa yakaita se heparin kana bivalirudin inoshanda nemaitiro akasiyana. Chiremba wako wemwoyo achasarudza sarudzo yakanakisa zvichienderana nerudzi rwechirongwa chako uye njodzi yemunhu.

Ko Abciximab Ari Nani Pane Clopidogrel Here?

Abciximab na clopidogrel vanoshanda zvakasiyana uye vanoshanda zvinangwa zvakasiyana mukuchengetwa kwemwoyo. Havasi vakwikwidzi vakananga - asi, vanowanzo shandiswa pamwe chete kuti vawane dziviriro yakanyanya.

Abciximab inopa kudzivirirwa kwegwamba rekukurumidza, kwakanyanya panguva yezvirongwa, nepo clopidogrel ichipa dziviriro yenguva refu yaunotora kumba. Funga nezve abciximab sedziviriro yekukurumidza uye clopidogrel sekuchengetedza zuva nezuva.

Zvekukurumidza panguva yezvirongwa zvemtima, abciximab inowanzo shanda zvakanyanya nekuti inoshanda nekukurumidza uye zvakakwana. Clopidogrel inotora mazuva kuti isvike pakushanda zvizere.

Zvisinei, clopidogrel yakachengeteka kushandiswa kwenguva refu uye haidi kuongororwa muchipatara. Chiremba wako anowanzo shandisa zvese zviri zviviri - abciximab panguva yekuita kwako uye clopidogrel kwemavhiki kana mwedzi mushure meizvozvo.

Mibvunzo Inowanzo Bvunzwa Nezve Abciximab

Abciximab Yakachengeteka Kune Vanhu vane Chirwere cheShuga Here?

Abciximab inogona kuva yakachengeteka kune vanhu vane chirwere cheshuga, asi matanho ekuwedzera anodiwa. Chirwere cheshuga chinogona kukanganisa hutano hwegadziriro yeropa nekupona, izvo chikwata chako chekurapa chichanyatso funga.

Vanhu vane chirwere cheshuga vanogona kuva nenjodzi yakati rebei yekubuda ropa. Madhokotera ako achakutarisa zvakanyanya uye anogona kuchinja muyero kana nguva yekurapa.

Kana uine diabetic retinopathy - matambudziko emaziso kubva kuchirwere cheshuga - chiremba wako achava akanyatso chenjerera. Ichi chimiro chinogona kuwedzera njodzi yekubuda ropa mumaziso.

Ndoitei Kana Ndikagamuchira Abciximab Yakawandisa Netsaona?

Haugone netsaona kugamuchira abciximab yakawandisa nekuti nyanzvi dzekurapa dzakadzidziswa dzinodzora muyero. Zvisinei, kana overdose ikaitika, kupindira kwekurapa nekukurumidza kunowanikwa.

Zvipatara zvine mitemo yakatarwa yekudzosa mhedzisiro yeabciximab. Izvi zvinogona kusanganisira platelet transfusions kana mamwe mishonga anodzosa kuumbwa kweropa kwakajairika.

Chikwata chekurapa chinotarisa mazinga ako ekuumbwa kweropa panguva yekurapa. Vanogona kukurumidza kuona kana mushonga uchiita zvakanyanya uye kugadzirisa zvinoenderana.

Ndoitei Kana Ndikakanganwa Dose yeAbciximab?

Kukanganwa dose yeabciximab hachisi chinhu chaunofanira kunetseka nacho. Mushonga unopihwa nguva dzose kuburikidza neIV, saka chikwata chekurapa chinodzora nguva.

Kana paine kukanganiswa mukuiswa kwako kweIV, vanamukoti vako vachaitangazve nekukurumidza. Vachaongorora kana uchida chero mishonga yekuwedzera yekuchengetedza.

Chikwata chako chekurapa chine mitemo yekubata chero kupi zvako kukanganiswa mukurapa. Vachaita shuwa kuti unowana huwandu hwakakodzera hwemishonga yechimiro chako.

Ndingamira Rini Kutora Abciximab?

Hauzvisarudzire kuti ungamira rini abciximab - chikwata chako chekurapa chinoita sarudzo iyi zvichienderana nemaitiro ako nekupora. Mishonga inowanzo mira yega mushure menguva yakatarwa.

Vazhinji varwere vanogamuchira abciximab kwemaawa gumi nemaviri kusvika makumi maviri nemana mushure mekuvhiyiwa kwemoyo kwavo. Chiremba wako achasarudza nguva chaiyo zvichienderana nekuti unopora sei zvakanaka uye njodzi yako yekubuda ropa.

Usati wamisa mishonga, chikwata chako chekurapa chichaita shuwa kuti nzvimbo yako yekuvhiyiwa yakagadzikana uye hausi panjodzi huru yekuvandudza magwamba. Vacharamba vachikutarisa kunyangwe mushure mekunge kupinza kwapera.

Ndingatyaira Mushure meKugamuchira Abciximab?

Haufanire kutyaira kwemaawa angangoita makumi maviri nemana mushure mekutora abciximab, uye zvichida kwenguva refu zvichienderana nemaitiro ako. Mishonga inogona kukonzera dzungu uye inowedzera njodzi yako yekubuda ropa kana wakuvadzwa.

Vanhu vazhinji vanogamuchira abciximab vari kupora kubva mukuvhiyiwa kwemoyo kunoda mazuva akati wandei ekuzorora. Chiremba wako achakuudza kana zvakachengeteka kutangazve mabasa akajairika sekutyaira.

Kunyangwe mushure mekunge mishonga yapera, ungangoda kudzivisa kutyaira kusvikira nzvimbo yako yekuvhiyiwa yapora zvizere. Izvi zvinokudzivirira kubva kumatambudziko kana uchida kumisa kamwe kamwe kana kufamba nekukurumidza.