Chii chinonzi Alectinib: Zvazvinoshandiswa, Madosi, Migumisiro Yemuviri uye Zvimwe

Alectinib mushonga wekenza unovavarira uyo unobatsira kurapa rudzi rwakati rwepfungwa kenza inonzi ALK-positive non-small cell lung cancer. Mushonga uyu unoshanda nekudzivisa mapuroteni akati wandei anobatsira maseru ekenza kukura nekupararira, zvichipa muviri wako mukana uri nani wekurwisa chirwere.

Kana iwe kana mumwe munhu waunoda akanyorerwa alectinib, ungangove uine mibvunzo yakawanda yekuti inoshanda sei uye zvekutarisira. Ngatitarisei zvese zvaunoda kuziva nezve mushonga uyu mumashoko akajeka, akarurama.

Chii chinonzi Alectinib?

Alectinib mushonga unonyorerwa chiremba uyo uri muboka remishonga inonzi tyrosine kinase inhibitors. Funga nezvazvo sechinhu chinovavarira kurapa chinonyanya kuenda kumasero ekenza ane shanduko yakati wandei yegeni.

Mushonga uyu wakagadzirirwa vanhu vane kenza yepfungwa ine shanduko yakati wandei yegeni inonzi ALK rearrangement. Chiremba wako achaedza maseru ako ekenza kuti aone kana aine shanduko iyi vasati vanyora alectinib.

Mushonga uyu unouya muchimiro chemakapsule uye unotorwa nemuromo, zvichiita kuti zvive nyore kupfuura kurapwa kunoda kushanya kuchipatara kuti utore infusions.

Chii chinonzi Alectinib chinoshandiswa?

Alectinib inonyanya kubvumidzwa kurapa ALK-positive non-small cell lung cancer. Rudzi urwu rwekenza yepfungwa runoumba anenge 3-5% yeese kenza yepfungwa, uye inowanzoitika muvanhu vadiki uye vasiri vaputi fodya.

Chiremba wako anogona kunyora alectinib sekurapa kwako kwekutanga kana wangobvunzwa kuti une rudzi urwu rwekenza. Inogonawo kushandiswa kana mamwe maALK inhibitors asina kushanda zvakanaka kwauri kana akamira kushanda.

Mushonga uyu unoshanda zvakanyanya kana kenza yapararira kune dzimwe nhengo dzemuviri wako, kusanganisira uropi. Zvidzidzo zvinoratidza kuti zvinogona kubatsira kuderedza tumor uye kunonotsa kukura kwekenza.

Alectinib inoshanda sei?

Alectinib inoshanda nekudzivisa protein inonzi ALK iyo inobatsira masero ekenza kukura nekuzara. Kana iyi protein yakanyanya kushanda nekuda kwekuchinja kwemajini, inotumira zviratidzo zvinoita kuti masero ekenza akure nekukurumidza.

Nekudzivisa zviratidzo izvi, alectinib inonyatsoisa mabhureki pakukura kwekenza. Izvi zvinopa immune system yako nemamwe marapirwo mukana wakanaka wekushanda kurwisa kenza.

Mishonga iyi inoonekwa semushonga wakasimba uye unoshanda wekenza yepfupa yeALK-positive. Vanhu vazhinji vanoona tuma tumor twavo tuchiderera mukati memwedzi mishoma yekutanga yekurapa.

Ndingatora sei Alectinib?

Tora alectinib sezvinorairwa nachiremba wako, kazhinji kaviri pazuva uine chikafu. Kuitora nechikafu kunobatsira muviri wako kutora mushonga zviri nani uye kunogona kuderedza dumbu.

Unogona kutora alectinib nechero rudzi rwechikafu, asi kuva nacho nechikafu chine mafuta anogona kubatsira pakutora. Usanetseke nezvekuisa nguva yacho nezvikafu zvakakosha - ingoita shuwa kuti hausi kuitora mudumbu risina chinhu.

Medza makapisi ese nemvura. Usavhura, kupwanya, kana kuitsenga, sezvo izvi zvinogona kukanganisa mashandiro emishonga. Kana uine dambudziko rekumedza makapisi, taura nachiremba wako nezveimwe nzira.

Edza kutora zvikamu zvako panguva imwe chete zuva rega rega kuti uchengetedze mazinga akagadzikana emushonga mumuviri wako. Kugadzirisa zviyeuchidzo zvefoni kunogona kukubatsira kuyeuka.

Ndingatora Alectinib kwenguva yakareba sei?

Iwe unowanzoenderera mberi nekutora alectinib chero ichibatsira kudzora kenza yako uye mhedzisiro yacho ichiramba ichidzoreka. Izvi zvinogona kuva mwedzi kana kunyange makore - mamiriro emunhu wese akasiyana.

Chiremba wako achatarisa kufambira mberi kwako nekutarisisa nguva dzose uye bvunzo dzeropa kuti aone kuti mushonga uri kushanda sei. Vachatsvaga zviratidzo zvekuti tuma tumor tiri kuderera kana kugara zvakagadzikana.

Kana kenza ikatanga kukura zvakare kana ukaona matambudziko akakomba, chiremba wako anogona kuchinja mushonga wako kana kukuchinjira kune mumwe mushonga. Ichi chikamu chakajairika chekuchengetwa kwekenza, kwete kukundikana kwemushonga.

Ndezvipi Zvinhu Zvinokonzerwa neAlectinib?

Semishonga yese, alectinib inogona kukonzera matambudziko, kunyangwe kwete munhu wese anoawana. Mazhinji ematambudziko anogadzirisika, uye timu yako yehutano ichakubatsira kubata chero anomuka.

Heano matambudziko anowanzoitika aunogona kusangana nawo, zvishoma nezvishoma kubva kune akanyanya kuwanda kuenda kune mashoma:

• Kuneta uye kunzwa kuneta kupfuura zvakajairika
• Kurwadziwa kwemhasuru uye kurwadziwa
• Kuzvimba mumaoko ako, tsoka, kana kumeso
• Kuvharika
• Kukosora
• Nausea
• Rash kana kutsamwa kweganda
• Kuchinja mukuona

Mazhinji ematambudziko aya akapfava kusvika pakati nepakati uye anowanzoita nani sezvo muviri wako uchigadzirisa kumushonga. Chiremba wako anogona kukurudzira nzira dzekuvagadzirisa zvinobudirira.

Mamwe matambudziko asingawanzoitiki asi akakomba anoda kutariswa kwekurapa nekukurumidza. Izvi zvinosanganisira kuoma kufema, kurwadziwa kwakanyanya kwemhasuru, shanduko dzakakosha dzemuono, kana zviratidzo zvematambudziko echiropa sekusviba kweganda rako kana maziso.

Kazhinji, alectinib inogona kukonzera kuzvimba kwemapapu kwakakomba kana kukuvadza chiropa zvakanyanya. Chiremba wako achakutarisa zvakanyanya nemiedzo yeropa yenguva dzose kuti abate chero matambudziko nekukurumidza.

Ndiani Asingafaniri Kutora Alectinib?

Alectinib haisi yemunhu wese. Hau faniri kutora mushonga uyu kana wakambove nekuita kwakanyanya kwemuviri kwauri kare kana kana kenza yako isina shanduko yeALK genetic.

Udza chiremba wako nezvemamiriro ako ese ehutano usati watanga alectinib. Izvi zvinonyanya kukosha kana uine matambudziko echiropa, chirwere chemapapu, kana nyaya dzemuono, sezvo mushonga ungaita kuti mamiriro aya aite kuipa.

Kana wakazvitakura, urikuronga kuzvitakura, kana kuti uri kuyamwisa, taura izvi nachiremba wako. Alectinib inogona kukuvadza mwana asati aberekwa, saka kudzora kubata pamuviri kwakakosha panguva yekurapa.

Chiremba wako achatarisawo mishonga yako yese kuti aone kana paine inopindirana. Dzimwe mishonga dzinogona kukanganisa mashandiro ealectinib kana kuwedzera njodzi yako yezvipingamupinyi.

Mazita eAlectinib Brand

Alectinib inotengeswa pasi pezita rekuti Alecensa munyika zhinji, kusanganisira United States. Iri ndiro zita rinowanzoonekwa pabhodhoro rako remishonga.

Mishonga iyi inogadzirwa neRoche/Genentech, uye unogona kuona zita ravo pakavha pamwe chete nezita rekuti Alecensa.

Mishonga ye generic yealectinib haisati yawandisa, saka vanhu vazhinji vanogamuchira vhezheni yezita remhando. Inishuwarenzi yako inogona kuva nezvido zvakakosha zvekuvharwa kwemishonga iyi.

Zvimwe Zvinhu Zviri Kufanana neAlectinib

Kana alectinib isiri yakanaka kwauri kana ikamira kushanda, mamwe marapirwo akatarisana anogona kurapa kenza yemapapu yeALK-positive. Chiremba wako angangofunga crizotinib, ceritinib, kana brigatinib sezvimwe zvinhu.

Imwe neimwe yemishonga iyi inoshanda zvishoma zvakasiyana uye ine maitiro ayo ezvipingamupinyi. Chiremba wako achasarudza sarudzo yakanakisa zvichienderana nemamiriro ako chaiwo, kusanganisira marapirwo aedzwa kare.

Mune dzimwe nguva, chiremba wako angakurudzira chemotherapy yechinyakare kana immunotherapy panzvimbo ye, kana pamwe chete ne, kurapwa kwakatarwa. Sarudzo inoenderana nezvinhu zvakawanda, kusanganisira maitiro akaita kenza yako kumishonga yapfuura.

Alectinib Ari Nani Kupfuura Crizotinib Here?

Zvidzidzo zvekiriniki zvinoratidza kuti alectinib inogona kunge iri nani pane crizotinib, kunyanya kudzivirira kenza kubva pakupararira kuuropi. Alectinib inowanzoitawo zvishoma zvipingamupinyi zvakakomba pane crizotinib.

Vanachiremba vazhinji zvino vanosarudza alectinib sechinhu chekutanga chekurapa kenza yemapapu yeALK-positive ichangobva kuongororwa. Zvisinei, mishonga yose iri miviri inoshanda, uye chiremba wako achasarudza zvichienderana nemamiriro ako ega.

Mishonga "iri nani" inoenderana nezvido zvako zvakananga, mamwe mamiriro ehutano, uye kuti muviri wako unoita sei kumishonga. Zvinoshanda zvakanyanya kune mumwe munhu zvingasava sarudzo yakanakisisa kune mumwe.

Mibvunzo Inowanzo Bvunzwa Pamusoro peAlectinib

Alectinib Yakachengeteka Here Kune Vanhu vane Chirwere Chemoyo?

Alectinib inowanzofungidzirwa kuti yakachengeteka kune vanhu vane matambudziko emoyo, asi chiremba wako achakutarisa zvakanyanya. Kusiyana nemimwe mishonga yekenza, alectinib haiwanzokonzera matambudziko akakomba emoyo.

Zvisinei, kana uine nhoroondo yechirwere chemoyo, chiremba wako anogona kuda kutarisa basa remoyo wako usati watanga kurapwa uye nguva nenguva panguva yekurapwa. Vanogonawo kugadzirisa muyero wako kana zvichidikanwa.

Ndoitei Kana Ndikatora Alectinib yakawanda netsaona?

Kana ukatora alectinib yakawanda netsaona kupfuura yakarairwa, taura nachiremba wako kana nzvimbo yekudzora muchetura nekukasika. Usamirira kuti uone kana zviratidzo zvichivapo - zviri nani kuwana zano rekurapa nekukasira.

Kutora alectinib yakawanda kunogona kuwedzera njodzi yako yemigumisiro yakakomba. Chikwata chako chehutano chinogona kuda kukutarisa zvakanyanya kana kupa kurapwa kwakakosha zvichienderana nekuti wakatora mishonga yakawanda sei.

Ndoitei Kana Ndikakanganwa Dose yeAlectinib?

Kana ukakanganwa dose uye zvapfuura maawa matanhatu kubva panguva yako yakarongwa, tora dose yakakanganwa nechikafu. Kana zvapfuura maawa anopfuura matanhatu, siya dose yakakanganwa uye tora dose yako inotevera panguva yakajairika.

Usambofa wakatora madosi maviri panguva imwe chete kuti ugadzirise dose yakakanganwa. Izvi zvinogona kuwedzera njodzi yako yemigumisiro pasina kupa rubatsiro rwakawedzerwa.

Ndingamira Rini Kutora Alectinib?

Regai kumwa alectinib chete kana chiremba wako akuudza kudaro. Kunyangwe kana uchinzwa zviri nani, mushonga unogona kunge uchiri kushanda kudzora kenza yako.

Chiremba wako achasarudza kuti ungamira rini zvichienderana nekuti kenza yako iri kupindura sei, mhedzisiro yaunowana, uye hutano hwako hwese. Vachashandisa ma scans uye bvunzo dzeropa kuti vaite sarudzo iyi.

Ndinganwa Doro Ndiri Kutora Alectinib Here?

Zvidiki zvedoro zvinowanzoita zvakanaka uchi tora alectinib, asi zviri nani kuti utange wakurukura izvi nachiremba wako. Doro dzimwe nguva rinogona kuwedzera mhedzisiro yakaita sekuneta kana kusvotwa.

Kana ukamwa, namatira kuzvinhu zvine mwero uye teerera kuti muviri wako unopindura sei. Vamwe vanhu vanowana kuti doro rinovakanganisa zvakanyanya pavanenge vachirapwa kenza.