Chii chinonzi Alendronate uye Cholecalciferol: Zvinoshandiswa, Dosage, Side Effects uye Zvimwe

Alendronate uye cholecalciferol mushonga unosanganisa unovandudza mapfupa ako uye kudzivirira mabhureki. Mushonga uyu unosanganisa zvinosanganiswa zviviri zvakakosha: alendronate, iyo inomisa kurasikirwa kwemapfupa, uye cholecalciferol (vhitamini D3), iyo inobatsira muviri wako kutora calcium zviri nani. Pamwe chete, vanoshanda sechikwata kuchengetedza mapfupa ako aine hutano uye akasimba, kunyanya kana iwe uchibata ne osteoporosis kana uri panjodzi yekuiwana.

Chii chinonzi Alendronate uye Cholecalciferol?

Mushonga uyu unosanganisa zvinosanganiswa zviviri zvinotsigira mapfupa mune imwe piritsi riri nyore. Alendronate ndeyeboka remishonga inonzi bisphosphonates, iyo inobatsira kudzivirira mapfupa ako kubva pakuparara nekukurumidza. Cholecalciferol ingori vhitamini D3, vhitamini imwechete iyo ganda rako rinoita kana richinge richisangana nezuva.

Mapfupa ako anogara achizvivakazve muhupenyu hwako hwese. Funga nezvazvo sekugadzirisa imba - zvikamu zvekare zvinobvarurwa apo zvikamu zvitsva zvinovakwa. Sezvatikukura, maitiro ekubvarura anowanzo kumhanya apo kuvaka kunononoka. Mushonga uyu unosanganisa unobatsira kudzorera chiyero ichocho nekumisa kuparara uye kutsigira maitiro ekuvaka.

Mushonga uyu unobatsira zvakanyanya kune vanhu vane mapfupa akava matete kana akaputsika. Vanachiremba vazhinji vanouraya kana calcium yenguva dzose uye vitamin D supplements chete zvisina kukwana kuchengetedza simba remapfupa.

Chii chinonzi Alendronate uye Cholecalciferol chinoshandiswa?

Mushonga uyu unosanganisa unovandudza uye unodzivirira osteoporosis, mamiriro apo mapfupa anova asina simba uye anoputsika nyore nyore. Zvinobatsira zvakanyanya vakadzi mushure mekuenda kumwedzi, apo shanduko yehomoni inogona kukonzera kurasikirwa kwemapfupa nekukurumidza. Mushonga uyu unogonawo kubatsira varume vane osteoporosis uye vanhu vanotora mishonga inoderedza mapfupa.

Chiremba wako angakurudzira mushonga uyu kana wakambovhunikwa kubva mukudonha kudiki kana kukuvadzwa. Inogona kuderedza zvakanyanya njodzi yako yekuvhunikwa mune ramangwana mumuzongoza wako, chiuno, uye ruoko. Aya ndiwo nzvimbo dzakajairika uko kuputsika kunoenderana ne osteoporosis kunoitika.

Dzimwe nguva vanachiremba vanorayira mushonga uyu kudzivirira osteoporosis isati yatanga. Izvi zvinogona kuitika kana uine njodzi dzakadai senhoroondo yemhuri ye osteoporosis, kushandiswa kwenguva refu kwema steroid, kana mamwe mamiriro ekurapa anokanganisa hutano hwemapfupa.

Mishonga iyi inoshandiswawo kurapa chirwere chePaget, mamiriro apo mapfupa anokura zvakanyanya uye asina simba. Muchiitiko ichi, alendronate inobatsira kujairika maitiro ekuvaka mapfupa.

Alendronate ne Cholecalciferol Zvinoshanda Sei?

Uyu mushonga une simba zvishoma unoshanda nemigwagwa miviri yakasiyana kudzivirira mapfupa ako. Chikamu che alendronate chinonamatira kunyama yako yemapfupa uye chinononotsa maseru anonzi osteoclasts, ayo anowanzo putsa mapfupa ekare. Nekunonotsa maitiro aya, mapfupa ako akawanda anoramba akabatana.

Chikamu che cholecalciferol (vhitamini D3) chinobatsira matumbu ako kutora calcium kubva muzvokudya zvinobudirira. Pasina vhitamini D yakakwana, muviri wako unogona chete kutora anenge 10-15% ye calcium yaunodya. Nevhitamini D yakakwana, nhamba iyoyo inokwira kusvika 30-40% kana kupfuura.

Apo izvi zviviri zvinoshanda pamwe chete, zvinogadzira simba rekudzivirira mapfupa. Iyo alendronate inochengetedza mapfupa aripo nepo vhitamini D ichivimbisa kuti muviri wako une calcium yaunoda kuvaka itsva, yakasimba mapfupa.

Iwe unowanzoona mabhenefiti mukati memwedzi mitatu-6, kunyangwe mhedzisiro yekudzivirira yakazara inokura pamusoro pegore rimwe-2 rekushandisa nguva dzose. Mishonga inovaka mumapfupa ako nekufamba kwenguva, ichipa dziviriro yakareba.

Ndingatora Sei Alendronate ne Cholecalciferol?

Kutora mushonga uyu nemazvo kwakakosha pakushanda kwavo nekuchengeteka. Unofanira kuutora mangwanani-ngwanani mudumbu risina chinhu nemvura yakazara. Usashandise kofi, muto, kana mukaka, nekuti izvi zvinogona kukanganisa kunyudzwa.

Mushure mekutora piritsi, unofanira kugara wakamira (wakagara kana kumira) kwemaminitsi angangoita 30. Izvi zvinodzivirira mushonga kubva mukutsamwisa esophagus yako, chubhu inobatanidza muromo wako mudumbu rako. Vanhu vazhinji vanoona zvichibatsira kutora mushonga wavo pavano muka, wobva waenda kunoita basa ravo remangwanani.

Mirira angangoita maminitsi makumi matatu usati wadyisa, kunwa chimwe chinhu kunze kwemvura, kana kutora mamwe mishonga. Kudya kwako kwekutanga kwezuva kunofanirwa kusanganisira chikafu chine calcium yakawanda senge zvigadzirwa zvemukaka, miriwo yemashizha, kana chikafu chakawedzerwa kuti chishande pamwe chete nevhitamini D mumushonga wako.

Vanhu vazhinji vanotora mushonga uyu kamwechete pavhiki, kazhinji pazuva rimwechete vhiki rega rega. Sarudza zuva rinoshanda nehurongwa hwako uye unamate kwairi. Kuisa chirangaridzo pafoni kunogona kukubatsira kuyeuka mushonga wako wevhiki nevhiki.

Kana uine dambudziko rekumedza mapiritsi, usava putsa kana kuatsenga. Pane kudaro, taura nachiremba wako nezveimwe nzira dzemvura kana mamwe mafomu anogona kushanda zviri nani kwauri.

Ndingatora Alendronate na Cholecalciferol kwenguva yakareba sei?

Vanhu vazhinji vanotora mushonga uyu kwemakore 3-5 pakutanga, kunyangwe vamwe vachigona kuda kurapwa kwenguva refu. Chiremba wako achatarisa kuwanda kwemapfupa ako uye hutano hwako hwese kuti uone nguva yakakodzera kwauri. Mushonga uyu unoenderera mberi uchishanda mumapfupa ako kunyangwe ukamira kuutora, uchipa dziviriro inoenderera mberi.

Mushure memakore 3-5, chiremba wako anogona kukurudzira

Vamwe vanhu vane njodzi yakanyanya yekutyoka kana mamwe mamiriro ezvinhu ekurapa vangangoda kutora mushonga kwenguva refu. Chiremba wako achayerera mabhenefiti ekuenderera mberi nekudzivirira mapfupa achipesana nenjodzi ipi neipi yenguva refu.

Panguva yekurapa, iwe uchava nekuongororwa kwemapfupa nguva dzose, kazhinji makore 1-2 ega ega. Miedzo iyi inobatsira chiremba wako kutevera kuti mushonga uri kushanda sei uye kutungamira sarudzo dzekuenderera mberi kana kugadzirisa kurapwa kwako.

Ndezvipi Zvipingamupinyi zveAlendronate neCholecalciferol?

Vanhu vazhinji vanotsungirira mushonga uyu zvakanaka, asi semishonga yese, inogona kukonzera mhedzisiro. Nyaya dzakajairika ndedzekureruka uye dzinokanganisa hurongwa hwako hwekugaya. Kunzwisisa zvekutarisira kunogona kukubatsira kuti unzwe wakavimbika nezvekurapa kwako.

Heano mhedzisiro yaungangove uine, uchifunga kuti vanhu vazhinji havana mhedzisiro zvachose:

• Kusagadzikana mudumbu kana kusvotwa, kunyanya kana kusatorwa zvakanaka
• Heartburn kana acid reflux
• Kuzvimbirwa kana manyoka
• Kutemwa nemusoro
• Kurwadziwa kwemhasuru kana majoini
• Dizziness

Izvi zvinowanzoitika zvinowanzoita nani sezvo muviri wako uchigadzirisa kumushonga. Kutora mushonga sezvakarairwa uye kugara wakamira mushure meizvozvo kunogona kudzivirira nyaya dzakawanda dzekugaya.

Mhedzisiro yakakomba haisi yakajairika asi yakakosha kuziva. Kunyange izvi zvichikanganisa vashoma vanopfuura 1 kubva pa100 vanhu, unofanirwa kuziva zvekutarisa:

• Heartburn yakakomba kana kuoma kumedza
• Kurwadziwa kwemuchipfuva kutsva kana kuwedzera
• Kurwadziwa kwakanyanya kwemashaya kana kuzvimba
• Kurwadziwa kwakajairika kwegumbo kana chiuno
• Zviratidzo zvecalcium yakaderera semakumbo emhasuru kana kunzwa

Mhedzisiro isingawanzoitiki asi yakakomba inosanganisira osteonecrosis yemashaya (matambudziko emapfupa emashaya) uye atypical femur fractures (kusanzwisisika kwegumbo remukati). Izvi zvinoitika muvanhu vashoma vanopfuura 1 kubva pa1,000 vachitora mushonga kwenguva refu.

Kana uine marwadzo anoramba aripo emumashaya, kunyanya mushure mekuvhiyiwa kwemazino, kana marwadzo asingawanzoitika emugumbo, fonera chiremba wako nekukurumidza. Izvi zvinokonzeresa zvisingawanzoitiki zvinowanzoitika mushure memakore ekushandisa, ndosaka chiremba wako achinyatso tarisa kurapwa kwako.

Ndiani Asingafaniri Kutora Alendronate uye Cholecalciferol?

Mishonga iyi haina kukodzera munhu wese, uye chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati ainyora. Mamwe mamiriro anoita kuti mushonga usachengeteke kana kushanda zvishoma, saka zvakakosha kuti ukurukure hutano hwako hwese.

Haufaniri kutora mushonga uyu kana uine matambudziko neesophagus yako, chubhu inotakura chikafu kubva mumuromo mako kuenda mudumbu rako. Izvi zvinosanganisira mamiriro akadai sekusimba, kuoma kumedza, kana nhoroondo yematambudziko eesophageal.

Vanhu vane chirwere chakakomba cheitsvo havawanzo kutora mushonga uyu zvakachengeteka. Itsvo dzako dzinobatsira kugadzirisa mushonga, uye kana dzisingashande zvakanaka, mushonga unogona kuungana kusvika pamatanho ane njodzi mumuviri wako.

Kana uine mazinga mashoma ecalcium yeropa, chiremba wako achada kugadzirisa izvi usati watanga mushonga. Kutora alendronate ine calcium yakaderera kunogona kuita kuti dambudziko riwedzere uye kukonzera matambudziko akakomba.

Iwe zvakare haufaniri kutora mushonga uyu kana usingakwanise kugara kana kumira wakatwasuka kwemaminitsi makumi matatu. Izvi zvinogona kunge zvichikonzerwa nenyaya dzekufamba, matambudziko emusana, kana mamwe mamiriro ehutano anoda kuti urare kazhinji.

Vakadzi vane pamuviri kana vanoyamwisa havafaniri kutora mushonga uyu, sezvo unogona kukanganisa mapfupa nemeno emwana ari kukura. Kana uri kuronga kuva nepamuviri, kurukura izvi nachiremba wako kare.

Alendronate uye Cholecalciferol Mazita eBrand

Mishonga iyi yakasanganiswa inowanikwa pasi pemazita akati wandei ebrand, Fosamax Plus D ndiyo inonyanya kuzivikanwa. Mamwe mazita akajairika ebrand anosanganisira Binosto Plus uye akasiyana siyana egeneric vhezheni ane zvinhu zvakafanana zvinoshanda.

Mishonga yakajairika inoshanda zvakanyanya semishonga yemhando uye kazhinji inodhura zvishoma. Murapi wako wemishonga anogona kukubatsira kunzwisisa kuti ndeyipi vhezheni yaunogamuchira uye kuona kuti uri kuitora nemazvo.

Mamwe mabhurendi anopa mafomu akasiyana, senge mahwendefa anonyungudika mumvura. Izvi zvinogona kuve nyore kutora kana uine dambudziko rekumedza mapiritsi, asi achiri kuda nguva imwechete uye kumira wakamira mushure mekutora.

Nguva dzose tarisa nemurapi wako wemishonga kana mushonga wako uchitaridzika zvakasiyana nezvaunojaira. Vagadziri vakasiyana vanogona kushandisa mavara akasiyana kana maumbirwo, asi zvinoshanda zvinoramba zvakafanana.

Zvimwe zvekutora panzvimbo peAlendronate neCholecalciferol

Kune dzimwe nzira dzakawanda kana mushonga uyu usingakukodzere kana usingashande zvakanaka. Mamwe ma bisphosphonates senge risedronate kana ibandronate anoshanda zvakafanana asi anogona kuve nemarongero akasiyana ekushandisa kana mhedzisiro.

Mishonga mitsva inonzi RANK ligand inhibitors, senge denosumab, inoshanda zvakasiyana nekunangana nemaseru chaiwo anoputsa mapfupa. Izvi zvinopihwa semajekiseni mwedzi mitanhatu yega yega uye zvinogona kukodzera kana usingakwanise kutora mishonga yemuromo.

Hormone replacement therapy inogona kubatsira vakadzi vakapfuura menopause kuchengetedza kuwanda kwemapfupa, kunyangwe ichiine njodzi dzakasiyana uye mabhenefiti anoda kufungwa zvakanyanya nachiremba wako.

Kune vamwe vanhu, shanduko yehupenyu yakasanganiswa necalcium uye vitamin D supplements inogona kukwana. Iyi nzira inoshanda zvakanyanya kune vanhu vane kurasikirwa kwemapfupa kwakapfava kana avo vane njodzi shoma yekutyoka.

Chiremba wako achafunga nezve mamiriro ako chaiwo, kusanganisira zera rako, njodzi yekutyoka, mamwe mamiriro ehutano, uye zvaunofarira pachako paunenge uchikurudzira dzimwe nzira.

Ko Alendronate neCholecalciferol zviri nani pane Calcium Supplements chete here?

Mishonga iyi yakasanganiswa inoshanda zvakanyanya kupfuura zvinowedzera calcium chete pakudzivirira mapfupa uye kurapa osteoporosis. Nepo zvinowedzera calcium zvichipa zvivakwa zvemapfupa, hazvigadzirise dambudziko riri pasi rekutyoka kwemapfupa akawandisa.

Zvidzidzo zvinoratidza kuti alendronate uye cholecalciferol inogona kuderedza mapfupa emuzongoza ne40-50% uye mapfupa ehip ne30-40%. Zvinowedzera calcium chete zvinowanzo deredza njodzi yekutyoka ne10-15% chete, uye dzimwe zvidzidzo dzinoratidza kuti hapana chakanaka zvachose.

Chikamu chevhitamini D mumushonga uyu zvakare chakavimbika kupfuura zvinowedzera vhitamini D zvakasiyana. Vanhu vazhinji havanyatso tora vhitamini D kubva mumuviri wavo wekugaya chikafu, asi fomu chaiyo mumusanganiswa uyu inoshanda zvakanyanya.

Zvisinei, zvinowedzera calcium zvichiri kutamba basa rakakosha muhutano hwemapfupa. Vanachiremba vazhinji vanokurudzira kuenderera mberi nezvikafu zvakapfuma mu calcium kana zvinowedzera pamwe chete nemushonga uyu kuti vape zvinhu zvakagadzirwa nemapfupa ako zvaanoda pakuvaka nyama itsva.

Funga nezvazvo nenzira iyi: zvinowedzera calcium zvakaita sematanda ekuvaka imba, nepo mushonga uyu wakaita sematanda nevashandi vane hunyanzvi vanoziva kuashandisa nemazvo.

Mibvunzo Inowanzo Bvunzwa Nezve Alendronate uye Cholecalciferol

Alendronate uye Cholecalciferol Zvakachengeteka Kune Vanhu vane Chirwere Chemoyo Here?

Mushonga uyu unowanzo chengeteka kune vanhu vane chirwere chemoyo, uye chikamu chevhitamini D chinogona kupa zvimwe zvinobatsira pamoyo. Zvisinei, unofanira kuudza chiremba wako nezve chero mishonga yemoyo yaunotora, sezvo imwe ichigona kushamwaridzana nevhitamini D.

Mushonga hauna zvakananga kukanganisa rhythm yemoyo kana blood pressure, zvichiita kuti ive yakakodzera kune vanhu vazhinji vane mamiriro emwoyo. Zvimwe zvidzidzo zvinototaura kuti mapfupa akasimba anogona kuve akabatana nehutano hwemoyo huri nani.

Kana ukatora mishonga yekutapudza ropa kana mishonga yemoyo, chiremba wako angada kukutarisa zvakanyanya, kunyanya paunotanga mushonga. Vhitamini D inogona kukanganisa maitiro anoita muviri wako mishonga.

Ndingaita Sei Kana Ndakatora Alendronate ne Cholecalciferol Zvakanyanya?

Kana ukatora dose yakawedzerwa netsaona, usavhunduka, asi taura nachiremba wako kana muzvinemishonga kuti uwane gwara. Kutora zvakanyanya kunogona kuwedzera njodzi yako yekutsamwa mudumbu uye mazinga mashoma ecalcium yeropa.

Inwa mvura yakawanda uye dzivisa kurara pasi kwemaawa akati wandei mushure mekuwandisa. Izvi zvinobatsira kudzivirira mushonga kubva pakutsamwisa esophagus yako. Usaedze kuzviita kurutsa, sezvo izvi zvinogona kukonzera kutsamwa kwakawedzerwa.

Tarisa zviratidzo zvecalcium yakaderera, senge mhasuru dzemhasuru, kunzwa kunyorova mumunwe wako kana zvigunwe, kana kuneta kusinganzwisisike. Kana uine zviratidzo izvi, tsvaga rubatsiro rwekurapa nekukurumidza.

Kuti udzivise tsaona dzemunguva yemberi, funga kushandisa chirongwa chemapiritsi kana kuseta zviyeuchidzo zvefoni. Sezvo mushonga uyu uchitorwa vhiki nevhiki, zviri nyore kukanganwa kana wakatora dose yako.

Ndingaita Sei Kana Ndikakanganwa Dose yeAlendronate ne Cholecalciferol?

Kana ukakanganwa dose yako yevhiki uye ukuyeuka mukati mezuva rimwe kana maviri, itore nekukurumidza sezvaunoyeuka, uchitevera maitiro emangwanani akafanana. Wobva wadzokera kuchirongwa chako chevhiki nevhiki vhiki rinotevera.

Kana zvapfuura mazuva anopfuura 2-3 kubva padosi yako yakakanganwa, isvetuke uye tora dose yako inotevera pazuva rako renguva dzose. Usatore madosi maviri pedyo, sezvo izvi zvinowedzera njodzi yemigumisiro isina kupa mamwe mabhenefiti.

Kukanganwa dose dzimwe nguva hakuzokuvadzi mapfupa ako zvakanyanya, sezvo mushonga unogara uchishanda mumuviri wako kwemavhiki. Zvisinei, edza kuchengetedza kuenderana kuti uwane mhedzisiro yakanakisisa.

Funga nezvekubatanidza mushonga wako wevhiki nevhiki nebasa renguva dzose, sekudzidza pepa reSvondo kana kugadzirira chikafu chevhiki nevhiki. Izvi zvinoita kuti zvikuyeuchidzwe nyore uye zvinovaka tsika muhurongwa hwako.

Ndingamira rini kutora Alendronate na Cholecalciferol?

Usambomira kutora mushonga uyu usati wataurirana nachiremba wako kutanga. Kunyangwe ukanzwa zvakanaka, kumira kamwe kamwe kunogona kutungamira mukurasikirwa kwemapfupa zvakare uye kuwedzera njodzi yekutyoka mukati memwedzi.

Chiremba wako anowanzoongorora kudiwa kwako kwekurapa kunoenderera mberi mushure memakore 3-5. Ongororo iyi inosanganisira kuongororwa kwemapfupa, kuongororwa kwenjodzi yekutyoka, uye kuongorora chero mhedzisiro yaunowana.

Vamwe vanhu vanogona kutora zvakachengeteka

Kana uchitora mishonga yakawanda mangwanani, shanda nemushonga wako kuti ugadzire chirongwa chinovimbisa kupatsanurwa kwakakodzera uchikodzera muhurongwa hwako hwezuva nezuva. Vanhu vazhinji vanoona zvichibatsira kutora mushonga wavo wemapfupa mangwanani-ngwanani, wobva watora mimwe mishonga nesarura.