Chii chinonzi Aminolevulinic Acid (Nzira Yemuromo): Zvinoshandiswa, Mishonga, Migumisiro Yemuviri uye Zvimwe

Aminolevulinic acid (ALA) chinhu chinoitika zvakasikwa chinogadzirwa nemuviri wako sechikamu chekugadzira maseru matsvuku eropa. Kana ichitorwa semushonga, inoita semumiririri wephotosensitizing, zvinoreva kuti inoita kuti maseru akati wandei ave nyore kuona chiedza. Iyi pfuma yakasarudzika inobvumira vanachiremba kuishandisa mukurapa kwakakosha kunonzi photodynamic therapy, kunyanya kune mamwe marudzi ezvirwere zvepaganda uye kenza.

Chii chinonzi Aminolevulinic Acid?

Aminolevulinic acid ikomponi iyo muviri wako unogadzira zvakasikwa mumari shoma zuva rega rega. Mushonga wemuromo une synthetic vhezheni yechinhu chimwe chete ichi, chakagadzirirwa kuunganidza mumasero asina kujairika mumuviri wako wese. Funga nezvazvo semubatsiri akatarisirwa anoratidza nzvimbo dzeproblemu dzekurapa.

Mushonga unoshanda nekutorwa zvakanyanya nemasero anokura nekukurumidza kana asina kujairika, senge maseru ekenza kana tishu isati yave nekenza. Kana maseru aya akatora aminolevulinic acid, anova nyore kuona wavelengths yakati wandei yechiedza, iyo inogona kushandiswa kurapa kuaputsa.

Chii chinonzi Aminolevulinic Acid chinoshandiswa?

Kushandiswa kukuru kweaminolevulinic acid yemuromo ndeye photodynamic therapy kune mamwe mamiriro ezvinhu ekurapa. Chiremba wako angakupa mushonga kuti akubatsire kuongorora kana kurapa mamwe marudzi ekukura kwetishu isina kujairika, kunyanya munzvimbo dzakaoma kusvika nemishonga yepamusoro.

Zvishandiso zvakajairika zvinosanganisira kurapa mamwe mamiriro ebladder, kunyanya isiri-muscle invasive bladder cancer uye carcinoma in situ. Vamwe vanachiremba vanoishandisawo pakuona tishu isina kujairika mubladder panguva yekuvhiya, sezvo nzvimbo dzakabatwa dzichipenya pasi pechiedza chebhuruu chakakosha, zvichiita kuti zvive nyore kuziva nekubvisa.

Mune dzimwe nguva, chiremba wako anogona kukurudzira aminolevulinic acid yekushandiswa kunze kwemavara, sekurapa mamwe mamiriro eganda kana mamwe marudzi ekenza yepamusoro. Zvisinei, kushandiswa uku hakusi kwakajairika uye kunoda kufunga zvakanyanya nezve mabhenefiti nenjodzi.

Aminolevulinic Acid Inoshanda Sei?

Aminolevulinic acid inoonekwa semushonga une simba repakati nepakati unoshanda kuburikidza nemaitiro ebiological anofadza. Paunotora nemuromo, inofamba kuburikidza neropa rako uye inotorwa nemaseru mumuviri wako wese, nemaseru asina kujairika achitora yakawanda kupfuura maseru ane hutano.

Mukati memaseru aya anotariswa, aminolevulinic acid inoshanduka kuita chinhu chinonzi protoporphyrin IX, iyo inoita seantenna yechisikigo yechiedza. Kana chiremba wako akazoratidza nzvimbo yakabatwa kune chaiwo blue kana tsvuku chiedza wavelengths, protoporphyrin IX inotora simba iri uye inogadzira reactive oxygen species inoparadza maseru asina kujairika.

Maitiro aya anosarudzwa zvakanyanya, zvinoreva kuti inonyanya kukanganisa maseru ane matambudziko ichisiya tishu ine hutano isina kukuvadzwa zvakanyanya. Maitiro ese anowanzo tora maawa akati wandei kubva panguva yaunotora mushonga kusvika kurapwa kwechiedza kutanga, zvichibvumira kuunganidzwa kwakanyanya mumaseru anotariswa.

Ndinofanira Sei Kutora Aminolevulinic Acid?

Unofanira kutora aminolevulinic acid sezvinorayirwa nachiremba wako, kazhinji semadosi emuromo imwechete yakavhenganiswa nemvura. Mushonga unowanzo kuuya seupfu hunoda kunyungudutswa mumvura yakati wandei usati wamwa, uye timu yako yehutano ichagadzirira musanganiswa uyu kwauri.

Kutora mushonga mudumbu risina chinhu zvinowanzo kurudzirwa, sezvo chikafu chinogona kukanganisa kutora kwayo. Chiremba wako anogona kukukumbira kuti usadya kwemaawa angangoita 2-3 usati watora dose. Unogona kazhinji kutangazve kudya maawa anenge 4-6 mushure mekutora mushonga, kunze kwekunge chiremba wako akupa mamwe mirairo.

Nguva yekutora aminolevulinic acid yakakosha nekuti inoda nguva kuti iunganidze mumaseru anotarisirwa pamberi pekurapa nechiedza kunotanga. Zvirongwa zvakawanda zvinoda kuti utore mushonga maawa 1-3 usati waita photodynamic therapy, zvichienderana nemamiriro chaiwo ari kurapwa.

Ndingatora Aminolevulinic Acid Kwenguva Yakareba Sei?

Aminolevulinic acid inowanzo kupiwa sedosi imwe chete panzvimbo yemushonga wenguva refu. Zvirongwa zvakawanda zvekurapa zvinosanganisira kutora dosi imwe chete pamberi pechikamu chimwe nechimwe chephotodynamic therapy, uye unogona kuda zvikamu zvakawanda zvakaparadzirwa mavhiki kana mwedzi.

Huwandu hwekurapa huchadiwa hunoenderana nemamiriro ako chaiwo uye kuti unopindura sei kurapa. Vamwe vanhu vanoona kuvandudzwa kukuru mushure mechikamu chimwe chete, nepo vamwe vachida kurapwa 2-4 kuti vawane mhedzisiro yaunoda. Chiremba wako achatarisa kufambira mberi kwako uye achasarudza chirongwa chekurapa chakakodzera mamiriro ako.

Pakati pekurapa, hauzotore aminolevulinic acid zuva nezuva. Pane kudaro, iwe unongozvitora pamazuva aunorongerwa photodynamic therapy, zvichiita kuti zvive zvakasiyana zvakanyanya kubva kune mamwe mishonga yaungave uchiziva.

Ndezvipi Zvakaipa zveAminolevulinic Acid?

Semushonga chero upi zvake, aminolevulinic acid inogona kukonzera mhedzisiro, kunyangwe vanhu vazhinji vachizvitsungirira zvakanaka. Kunzwisisa zvekutarisira kunogona kukubatsira kuti unzwe wakagadzirira uye uzive nguva yekubata timu yako yehutano.

Mhedzisiro yakajairika yaungasangana nayo inosanganisira kusvotwa, kurutsa, uye kusagadzikana mudumbu, kunyanya mumaawa mushure mekuwana dosi yako. Zviratidzo izvi zvekugaya zvinowanzoenda zvega mukati me24-48 maawa uye zvinowanzoitwa nemishonga inorwisa kusvotwa kana zvichidikanwa.

Heano mhedzisiro inowanzoziviswa iyo varwere vanosangana nayo:

• Kutadza kufara uye kurutsa (kunokanganisa vanenge 10-30% yevanhu vanorwara)
• Kurwadziwa mudumbu kana kukakavara
• Manyoka kana zvigaro zvakasununguka
• Kuneta kana kunzwa kusagadzikana
• Kutemwa nemusoro
• Dizziness kana lightheadedness

Izvi zvinowanzoitika zvinowanzoitika zvinyoro kusvika pakati nepakati uye kwenguva pfupi. Vanhu vazhinji vanowana kuti kugara vakanyoroveswa uye kuzorora kunobatsira kubata zviratidzo izvi zvinobudirira.

Zvimwe zvinokanganisa zvakanyanya hazviwanzoitiki asi zvinoda kutariswa kwekurapa nekukurumidza. Unofanira kubata chiremba wako nekukurumidza kana ukaona maitiro akakomba ekuita allergic, kusanganisira kuoma kufema, kuzvimba kwechiso chako kana huro, kana rash yakapararira. Uye zvakare, kurutsa kwakanyanya kana kuramba kuchidzika kunokutadzisa kuchengeta mvura pasi kunoda kuongororwa kwekurapa nekukurumidza.

Zvimwe zvisingawanzoitiki asi zvakakosha zvinokanganisa zvinosanganisira shanduko yebasa rechiropa, ndosaka chiremba wako angatarisa ma enzymes ako echiropa nemiedzo yeropa. Kazhinji, varwere vanogona kusangana nezvimwe zvinokanganisa mwoyo kana kuita kweganda kwakanyanya, kunyanya kana vakafumurwa nechiedza chakajeka nekukurumidza mushure mekurapa.

Ndiani Asingafaniri Kutora Aminolevulinic Acid?

Vanhu vakati wandei havafaniri kutora aminolevulinic acid nekuda kwekuwedzera njodzi yematambudziko kana kuderedzwa kwekubudirira. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa kuti aone kana mushonga uyu wakachengeteka kwauri.

Haufaniri kutora aminolevulinic acid kana uine allergy inozivikanwa kumushonga kana chero zvikamu zvawo. Uye zvakare, vanhu vane mamwe marara eropa, kunyanya porphyria (boka rezvirwere zvisingawanzoitiki zvinokanganisa makemikari eropa), vanofanira kudzivisa mushonga uyu sezvo uchigona kuwedzera mamiriro avo.

Mamwe mamiriro akati wandei anogona kuita kuti aminolevulinic acid isakunakire:

• Chirwere chakakomba cheitsvo kana kutadza kweitsvo
• Chirwere chakakomba chechiropa kana kutadza kwechiropa
• Kuzvitakura kana kuyamwisa
• Kubuda ropa kwakanyanya mudumbu
• Mamiriro emoyo akakomba kana kurwisa kwemoyo kwemazuva achangopfuura
• Mamwe mamiriro ekuzvimiririra anokanganisa kunzwa kwechiedza

Chiremba wako achatarisawo mishonga yaunotora parizvino, sezvo mamwe madhiragi anogona kukanganisa aminolevulinic acid kana kukanganisa nzira inoita muviri wako. Kuongorora uku kunovimbisa kuti kurapwa kwacho kwakachengeteka uye kunoshanda kumamiriro ako chaiwo.

Mazita eAminolevulinic Acid Brand

Aminolevulinic acid inowanikwa pasi pemazita akati wandei emhando, zvichienderana neiyo chaiyo fomula uye kushandiswa kwakatarwa. Fomu yemuromo inonyanya kunyorerwa inozivikanwa seGleolan munyika zhinji, kunyangwe kuwanikwa kuchisiyana nedunhu.

MuUnited States, iyo fomula yemuromo inogona kuwanikwa pasi pemazita akasiyana emhando kana semushonga wegeneric, zvichienderana neiyo chaiyo chiratidzo uye mugadziri. Pharmacy yako ichakupa iwe zita chairo remhando rakanyorwa nachiremba wako.

Zvakakosha kucherechedza kuti kune zvakare topical (zvinoshandiswa paganda) shanduro dzeaminolevulinic acid dziripo pasi pemazita akasiyana emhando, senge Levulan Kerastick. Zvisinei, izvi zvakasiyana zvachose mafomu uye hazvifaniri kuvhiringidzwa nemushonga wemuromo.

Aminolevulinic Acid Alternatives

Kana aminolevulinic acid isina kukodzera iwe, chiremba wako anogona kufunga nezveimwe nzira dzekurapa zvichienderana nemamiriro ako chaiwo. Kancer yeguvhu, dzimwe nzira dzinogona kusanganisira mamwe maagent photosensitizing kana nzira dzakasiyana zvachose dzekurapa.

Mishonga mimwe inogona kushandiswa panzvimbo pemishonga inowedzera kunzwisiswa kwechiedza inosanganisira methyl aminolevulinate (MAL) kana mamwe makomisheni ane porphyrin, kunyange izvi zvichiwanzoshandiswa kune mamwe mamiriro kana nzira dzekuendesa mishonga. Chiremba wako angangofungawo nezvekurapa kwakajairika senge chemotherapy, immunotherapy, kana sarudzo dzekuvhiya.

Sarudzo yekurapa kwakasiyana inoenderana zvakanyanya nekuongororwa kwako, hutano hwako hwese, uye zvinangwa zvekurapa. Chikwata chako chehutano chichashanda newe kuti uwane sarudzo yakakodzera kana aminolevulinic acid isiri sarudzo yakanaka yemamiriro ako ezvinhu.

Ko Aminolevulinic Acid iri nani pane mamwe maPhotosensitizers?

Aminolevulinic acid ine zvakawanda zvakanakira pamusoro pemimwe mishonga inowedzera kunzwisiswa kwechiedza, kunyanya maererano nekukurumidza kwayo kubva mumuviri wako. Kusiyana nemamwe ma photosensitizers anogona kukugadzira kuti unzwe chiedza kwemavhiki, aminolevulinic acid inowanzoita kuti unzwe chiedza kwemaawa makumi maviri nemana kusvika makumi mana nemasere chete.

Iyi nguva pfupi yekunzwa chiedza inoita kuti zvive nyore kune varwere uye inoderedza njodzi yekusangana nechiedza netsaona. Uye zvakare, aminolevulinic acid inowanikwa mumuviri wako, izvo zvinogona kuderedza njodzi yemamwe marudzi ekugadzirisa muviri kune zvimwe zvezvinhu zvakagadzirwa.

Zvisinei, sarudzo

Asidhi yeAminolevulinic inogona kushandiswa zvakachengeteka muvanhu vane chirwere cheshuga, asi chiremba wako achada kukutarisa zvakanyanya. Mushonga wacho pachake hauna zvakananga mazinga eshuga yeropa, asi kushushikana kwekurapa uye zvingaitika zvinokonzeresa zvakadai senausea kana kurutsa zvinogona kukanganisa kwenguva pfupi kutonga kweshuga yeropa rako.

Kana uine chirwere cheshuga, ita shuwa kuti unozivisa timu yako yehutano kuti vagadzirise kutariswa kwako uye pamwe mishonga yako yechirwere cheshuga panguva yekurapa. Unofanirawo kuronga kutarisa shuga yako yeropa kakawanda pamazuva ekurapa.

Ndingaita Sei Kana Ndakashandisa Asidhi yeAminolevulinic yakawandisa netsaona?

Kana netsaona ukatora asidhi yeaminolevulinic yakawanda kupfuura yakarairwa, taura nachiremba wako kana masevhisi ekukurumidzira nekukasira. Kudhakwa kunogona kuwedzera njodzi yezvipingamupinyi zvakakomba, kunyanya kuwedzera kunzwisiswa kwechiedza uye nausea yakanyanya kana kurutsa.

Usayedze kukonzera kurutsa kunze kwekunge wairairwa zvakananga nenyanzvi dzezvekurapa. Pane kudaro, tsvaga kutariswa kwekurapa nekukasira uko vanopa hutano vanogona kukutarisa kuti uve nematambudziko uye kupa rutsigiro rwakakodzera kana zvichidikanwa.

Ndingaita Sei Kana Ndikarasikirwa neDosi yeAsidhi yeAminolevulinic?

Sezvo asidhi yeaminolevulinic inowanzo kupiwa sedosi imwe chete isati yatanga photodynamic therapy, kupotsa dosi kazhinji zvinoreva kuronga zvakare chikamu chako chose chekurapa. Taura nechikwata chako chehutano nekukasira kana ukapotsa dosi yako yakarongwa.

Chiremba wako achada kuronga zvakare mushonga uye kurapwa kwechiedza, sezvo nguva pakati pezvikamu zviviri izvi yakakosha kuti zviite. Usaedze kutora mushonga wega kana kugadzirisa nguva pasina kutariswa kwekurapa.

Ndingamira Rini Kutora Asidhi yeAminolevulinic?

Hauwanzo "kumira" kutora aminolevulinic acid nenzira yechinyakare, sezvo inowanzo piwa semadosi ega ega panzvimbo yemushonga unopfuurira. Nzira yako yekurapa ichapedzwa kana wapedza zvese zvirongwa zvephotodynamic therapy zvakarongwa nachiremba wako.

Chiremba wako achasarudza kuti kurapwa kwako kwapera rini zvichienderana nekuti unopindura sei kurapa uye kana kurapwa kwekutevera kuchidiwa. Vamwe vanhu vanoda chikamu chimwe chete, asi vamwe vangada kurapwa kwakawanda kwakapararira pamwedzi.

Ndingagona here Kutyaira Mushure meKutora Aminolevulinic Acid?

Unofanira kudzivisa kutyaira mushure mekutora aminolevulinic acid, kunyanya pazuva rekurapa. Mushonga uyu unogona kukonzera dzungu, kusvotwa, uye kuneta izvo zvinogona kukanganisa kugona kwako kutyaira zvakachengeteka.

Uyezve, uchada kudzivisa kuratidzwa kwechiedza chakajeka kwemaawa makumi maviri nemana kusvika makumi mana nemasere mushure mekurapa, izvo zvinosanganisira zuva rinopenya raungasangana naro uchityaira. Ronga kuti mumwe munhu akutyairire kuenda nekubva kumisangano yako yekurapa uye kwemazuva angangoita ekutanga mushure mechikamu chimwe nechimwe.