Chii chinonzi Azathioprine: Zvinoshandiswa, Madosi, Matambudziko uye Zvimwe

Azathioprine mushonga unopiwa nachiremba unobatsira kudzikamisa immune system inoshanda zvakanyanya. Iyo ndeyeboka remishonga inonzi immunosuppressants, iyo inoshanda nekuderedza mhinduro dzemuviri dzemuviri dzemuviri kana dzichiva dzakanyanya kana kutanga kurwisa matishu ane hutano.

Mushonga uyu wakashandiswa zvakachengeteka kwemakumi emakore kurapa mamiriro akasiyana-siyana eautoimmune uye kudzivirira kurambwa kwenhengo mushure mekuisa nhengo. Kunyange zvazvo zvichida kutariswa zvakanaka, azathioprine inogona kuchinja hupenyu zvechokwadi kune vanhu vanobata nemamiriro ezvinhu apo immune system yavo inoda kutungamirirwa zvinyoro nyoro kuti ishande zvakanaka.

Chii chinonzi Azathioprine Chinoshandiswa Kuti?

Azathioprine inoshanda sechinhu chikuru chekurapa mamiriro akakomba ekurapa apo immune system yako inoda kutarisirwa zvakanaka. Chiremba wako angangokupa mushonga uyu kana muviri wako wekudzivirira uri kushanda zvakanyanya kana kutarisira zvinhu zvisiri izvo.

Mushonga uyu unonyanya kushandiswa kudzivirira muviri wako kuramba nhengo yakaiswa, senge itsvo kana chiropa. Inoshanda pamwe chete nemimwe mishonga kubatsira muviri wako kugamuchira nhengo itsva sechikamu chayo pachayo panzvimbo yekurwisa.

Kupfuura kutarisirwa kwekuisa nhengo, azathioprine inoratidza kukosha kwayo kurapa zvirwere zveautoimmune. Aya mamiriro apo immune system yako inokanganisa kurwisa matishu ako ane hutano, zvichikonzera kuzvimba uye kukuvadza mumuviri wako wose.

Heano mamiriro makuru apo azathioprine inogona kuita mutsauko chaiwo muhutano hwako:

• Arthritis yeRheumatoid, kunyanya kana dzimwe nzira dzekurapa dzisina kupa zororo rakakwana
• Zvirwere zvinopisa ura zvakaita sechirwere chaCrohn ne ulcerative colitis
• Mhosva dzakakomba dze systemic lupus erythematosus
• Mhando dzakasiyana dze vasculitis, uko tsinga dzeropa dzinopisa
• Myasthenia gravis, mamiriro anokanganisa simba remhasuru
• Eczema yakakomba kana dermatitis isingapinduri kune dzimwe nzira dzekurapa
• Mamwe mafomu e hepatitis anokonzerwa nekupindura kwe autoimmune

Muzviitiko zvisingawanzoitiki, chiremba wako angangofunga azathioprine yezvirwere zvakaita se psoriasis yakakomba, mamwe marudzi ekuputika kwemaziso, kana zvirwere zveropa zvakakosha. Sarudzo inogara ichienderana nemamiriro ako ega uye kuti dzimwe nzira dzekurapa dzakashanda sei kwauri.

Azathioprine Inoshanda Sei?

Azathioprine inoshanda nekunonotsa zvinyoro nyoro basa re immune system yako, kunyanya ichinangana nemaseru anokonzera kuzvimba uye kukuvadzwa kwetishu. Funga nezvazvo sekudzikisa vhoriyamu pane mhinduro ye immune inofarira zvakanyanya pane kuibatidza zvachose.

Mishonga inoshandurwa mumuviri wako kuita makomisheni anoshanda anokanganisa maitiro emaseru e immune anowedzera uye kushanda. Iyi nzira inoitika zvishoma nezvishoma, ndosaka azathioprine ichionekwa seyakasimba-pakati immunosuppressant pane imwe ine simba.

Kusiyana nemishonga ine simba yekudzivirira immune, azathioprine inobvumira immune system yako kuti ichengetedze zvakawanda zvekukwanisa kwayo kurwisa zvirwere nezvirwere. Zvakafanana nekushandisa mabhureki akapfava kumotokari pane kuvhara pakumira kwemhepo.

Mishonga inonyanya kunangana nemaseru anokurumidza kupatsanurwa, kusanganisira maseru e immune anopfuura anokonzera mamiriro ako. Iyi nzira yekusarudza inobatsira kutsanangura nei azathioprine ichigona kushanda pasina kukanganisa zvachose dziviriro yemuviri wako yechisikigo.

Ndinofanira Kutora Sei Azathioprine?

Kutora azathioprine nemazvo kunobatsira kuona kuti unowana zvakanakisa zvichideredza matambudziko anogona kuitika. Chiremba wako achakupa mirairo yakatarwa zvichienderana nemamiriro ako uye kuti muviri wako unopindura sei kumushonga.

Vanhu vazhinji vanotora azathioprine nemuromo, kazhinji kamwe kana kaviri pazuva vaine chikafu kana mukaka. Kuitora nechikafu kunobatsira kuderedza dumbu rinogumbuka, iro vanhu vamwe vanowana pavanotanga mushonga.

Fomu reintravenous rinowanzo chengeterwa nzvimbo dzekuchipatara kana iwe usingakwanise kutora mapiritsi nemuromo. Kana iwe uchigamuchira IV azathioprine, timu yako yehutano ichabata nekupa uye kukutarisa zvakanyanya panguva yekuita.

Hezvino zvaunofanira kuziva nezvekutora azathioprine nemazvo:

• Tora panguva imwechete zuva rega rega kuti uchengetedze mazinga akagadzikana mumuviri wako
• Medza mahwendefa ese negirazi remvura izere
• Usambofa wakapwanya kana kuputsa mahwendefa, sezvo izvi zvinogona kukanganisa mashandiro emushonga
• Kana ukanzwa kusvotwa, edza kuitora nechikafu kana zvakananga mushure mekudya
• Ramba uchiitora kunyangwe ukanzwa zvakanaka, sezvo kumira kamwe kamwe kunogona kukonzera mamiriro ako kuti abude

Chiremba wako achakutanga padosi yakaderera uye zvishoma nezvishoma achiigadzirisa zvichienderana nekuti unopindura sei uye chero matambudziko aungasangana nawo. Iyi nzira yekuchenjerera inobatsira kuwana chiyero chakakodzera zvinodiwa zvako.

Ndingatora Azathioprine Kwenguva Yakareba Sei?

Kureba kwekurapa kweazathioprine kunosiyana zvakanyanya zvichienderana nemamiriro ako chaiwo uye kuti unopindura sei kumushonga. Vamwe vanhu vanoiisa kwemwedzi mishoma chete, nepo vamwe vachigona kuitora kwemakore kana kunyange kwenguva refu.

Kune varwere vekutapurirana nhengo, azathioprine inowanzoita kuzvipira kwehupenyu hwese kudzivirira kurambwa. Chikwata chako chekutapurirana chichashanda newe kuti uwane dose yakaderera inoshanda iyo inochengetedza nhengo yako itsva iine hutano uye ichishanda zvakanaka.

Kana uri kutora azathioprine nokuda kwechirwere che autoimmune, nguva yacho inowanzoenderana nekuti chirwere chako chiri kushanda zvakadii uye kuti mamwe marapirwo anoshanda zvakanaka sei. Vanhu vazhinji vanowana kuti vanogona zvishoma nezvishoma kuderedza mushonga wavo kana kutomisa mushonga kana mamiriro avo achidzora zvakanaka.

Chiremba wako achagara achiongorora kana uchiri kuda azathioprine nekutarisa zviratidzo zvako, bvunzo dzeropa, uye hutano hwako hwese. Vanogona kukurudzira kuyedza kuderedza mushonga kana kutora zororo kubva kumushonga kana uri kufara.

Ndezvipi Zvakaipa zveAzathioprine?

Semishonga yese inokanganisa immune system yako, azathioprine inogona kukonzera mhedzisiro, kunyangwe vanhu vazhinji vachizvitsungirira zvakanaka. Kunzwisisa zvekutarisira kunogona kukubatsira kuti unzwe wakavimbika pamusoro pekurapa kwako uye kuziva nguva yekubata chiremba wako.

Mhedzisiro yakajairika inowanzoita nyoro uye inowanzoita nani muviri wako uchigadzirisa kumushonga. Izvi zvinowanzoita kuti zvisade kumisa mushonga, asi zvakakosha kuti ukurukure navo nemupi wako wehutano.

Heano mhedzisiro iwe yaunonyanya kuona:

• Kunyara kudiki kana dumbu kusagadzikana, kunyanya kana uchitanga
• Kuwedzera kutapukirwa nezvirwere zvidiki zvakaita sema colds
• Kuneta kana kunzwa kuneta kupfuura zvakajairika
• Kutetepa kwebvudzi kwenguva pfupi, iyo inowanzo dzokera mushure mekumisa mushonga
• Ganda rinonzwa zvishoma kune zuva
• Dhiria kana zvigaro zvakasununguka

Vamwe vanhu vanowana mhedzisiro yakakosha inoda kutarisa pedyo. Kunyange zvazvo izvi zvisingawanzoitiki, zvakakosha kuti utarise uye utaure kuchiremba wako nekukurumidza.

Mhedzisiro yakakomba inoda kutariswa kwekurapa inosanganisira:

• Fivha inoramba iripo, kutonhora, kana zviratidzo zvechirwere chakakomba
• Kubuda ropa kusinganzwisisike kana kupwanyika
• Kurwadziwa kwakanyanya mudumbu kana kurutsa kunoramba kuripo
• Kusvava kweganda kana maziso, izvo zvingaratidza matambudziko echiropa
• Kuneta kwakanyanya kusingavanduki nekuzorora
• Mavhundi asinganzwisisike kana kuzvimba chero kupi zvako pamuviri wako

Muzviitiko zvisingawanzoitiki, kushandiswa kwenguva refu kweazathioprine kunogona kuwedzera zvishoma njodzi yemamwe marudzi ekenza, kunyanya kenza yeganda uye lymphomas. Chiremba wako achakurukura njodzi iyi newe uye achatsanangura kuti kuongorora nguva dzose kunobatsira sei kubata chero matambudziko nekukurumidza.

Ndiani Asingafaniri Kutora Azathioprine?

Nepo azathioprine ichiwanzoita kuti ive yakachengeteka kune vanhu vazhinji, vamwe vanhu vanofanira kudzivisa mushonga uyu kana kuushandisa nekuchenjerera kwakanyanya. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akuraira.

Vanhu vane allergy inozivikanwa kune azathioprine kana imwe compound yayo, 6-mercaptopurine, havafaniri kutora mushonga uyu. Kana wakambove nezvinetso zvakakomba kumishonga yakafanana munguva yakapfuura, ita shuwa kuti chiremba wako anoziva nezvazvo.

Mamwe mamiriro ekurapa anoita kuti azathioprine isachengeteke zvishoma kana kuda kuongororwa kwakakosha. Chiremba wako achada kuyera mabhenefiti achipesana nenjodzi mumamiriro ezvinhu aya.

Unofanira kukurukura azathioprine zvakanyatsonaka nachiremba wako kana uine:

• Zvirwere zvinoshanda kana nhoroondo yezvirwere zvakakomba zvinodzokororwa
• Chirwere chechiropa kana nhoroondo yematambudziko echiropa
• Chirwere cheitsvo kana kushanda kweitsvo kwakaderedzwa
• Nhoroondo yekenza, kunyanya kenza yeropa
• Kusiyana kwemajini kunokanganisa maitiro ako ekugadzirisa mushonga
• Matambudziko akakomba emuongo wemapfupa kana zvirwere zveropa

Kuzvitakura nekuyamwisa zvinoda kufunga kwakakosha. Nepo azathioprine dzimwe nguva ichigona kushandiswa panguva yekuzvitakura kana mabhenefiti achipfuura njodzi, haisi sarudzo yekutanga yemamiriro mazhinji. Chiremba wako achakubatsira kuita sarudzo yakanakisa kwauri nemwana wako.

Kana muri kuronga kuva nemimba kana makatomboita nemimba, kurukurai izvi nemupi wehutano wenyu nekukurumidza sezvinobvira. Vanogona kuda kugadzirisa chirongwa chenyu chekurapa kana kukuchinjirai kune imwe nzira yakachengeteka.

Mazita eBrand eAzathioprine

Azathioprine inowanikwa pasi pemazita akati wandei ebrand, kunyangwe vhezheni ye generic ichishanda zvakanyanya uye inowanzoita mari shoma. Zita rebrand rinowanzozivikanwa rauchasangana naro iImuran, iyo yave iripo kwemakore mazhinji.

Mamwe mazita ebrand anosanganisira Azasan mune dzimwe nzvimbo, kunyangwe kuwanikwa kuchisiyana nenyika. Murapi wemishonga wenyu anogona kukubatsirai kunzwisisa kuti ndiyo vhezheni ipi yauri kuwana uye kana kuchinja pakati pemabhurandi kungakanganisa kurapwa kwenyu.

Mungave muchitora zita rebrand kana vhezheni ye generic, chinhu chinoshanda uye kushanda zvinoramba zvakafanana. Vamwe vanhu vanosarudza kunamatira kumugadziri mumwe chete kuti vave nechokwadi chekuenderana, nepo vamwe vachigutsikana nekuchinja zvichienderana nemutengo kana kuwanikwa.

Zvimwe Zvinhu Zviri Kutsiva Azathioprine

Kana azathioprine isiri yakanaka kwamuri kana ikamira kushanda nemazvo, mishonga yakati wandei inogona kupa mabhenefiti akafanana. Chiremba wenyu achasarudza sarudzo yakanakisa zvichienderana nemamiriro enyu chaiwo uye maitiro amakaita kune dzimwe nzira dzekurapa.

Kune mamiriro eautoimmune, methotrexate inowanzoonekwa seimwe nzira yakavharana. Inoshanda zvakasiyana neazathioprine asi inogona kushanda zvakaenzana kune vanhu vazhinji, kunyangwe ichiuya nezvayo zvekufunga uye zvinodiwa zvekutarisa.

Mishonga mitsva inonzi biologics inopa imwe sarudzo, kunyanya kune mamiriro akadai se rheumatoid arthritis uye inflammatory bowel disease. Izvi zvinosanganisira zvinodhaka zvakaita se adalimumab, infliximab, uye etanercept, iyo inotarisa zvikamu zvakakosha zve immune system.

Zvimwe zvingasarudzwa chiremba wenyu angatarisa zvinosanganisira:

• Mycophenolate mofetil, kunyanya kuvarwere vakaisirwa nhengo
• Leflunomide ye rheumatoid arthritis
• Cyclosporine ye severe autoimmune conditions
• Hydroxychloroquine ye lupus uye mamwe mamiriro akafanana
• Sulfasalazine ye inflammatory bowel disease

Sarudzo yeimwe nzira inotsamira pazvinhu zvakawanda, kusanganisira mamiriro ako chaiwo, mamwe mishonga yaunotora, uye maitiro ako pachako kumishonga yakasiyana. Chiremba wako achashanda newe kuti awane sarudzo yakanaka kana azathioprine isingashande zvakanaka kwauri.

Azathioprine Ari Nani Pane Methotrexate Here?

Ose ari maviri azathioprine uye methotrexate mishonga inodzvinyirira immune system, asi hapana kana imwe yacho iri nani pane imwe. Sarudzo inotsamira pamamiriro ako chaiwo, nhoroondo yako yezvokurapa, uye kuti muviri wako unopindura sei kumishonga yega yega.

Ye rheumatoid arthritis, methotrexate inowanzoedzwa kutanga nekuti yakadzidzwa zvakanyanya uye inoshanda nekukurumidza kune vanhu vazhinji. Zvisinei, azathioprine inogona kuva imwe nzira yakanaka kana methotrexate ichikonzera migumisiro kana isingashande zvakanaka.

Azathioprine inogona kufarirwa kana uine matambudziko echiropa, sezvo ichiita zvishoma pachiropa kupfuura methotrexate. Kune rimwe divi, methotrexate inogona kusarudzwa kana uine mamwe ma genetic variations anoita kuti azathioprine isashande zvakanaka.

Ye inflammatory bowel disease, azathioprine ine nhoroondo yakareba uye inowanzoita yekutanga immunosuppressant kuyedzwa. Zvisinei, mishonga yese inogona kushanda, uye sarudzo inowanzoenderana nezvinhu zvemunhu uye zvinofarirwa nachiremba.

Chiremba wako achafunga nezvezvinhu zvakaita sebasa rako reitsvo nechiropa, mamwe mishonga yaunotora, uye mararamiro ako paunenge uchisarudza pakati pezvisarudzo izvi. Vanhu vazhinji vanoita zvakanaka pamushonga wese, uye kuchinjana pakati pavo kunogara kuchibvira kana zvichidikanwa.

Mibvunzo Inowanzo Bvunzwa Nezve Azathioprine

Azathioprine Yakachengeteka Here Kune Vanhu vane Chirwere cheItsvo?

Azathioprine inogona kushandiswa kune vanhu vane chirwere cheitsvo, asi inoda kunyatso tariswa uye pamwe kugadzirisa muyero. Sezvo itsvo dzako dzichibatsira kugadzirisa nekubvisa mushonga, kushanda kwetsvo kwakaderera kunogona kukanganisa maitiro emuviri wako azathioprine.

Chiremba wako anogona kuraira bvunzo dzeropa dzenguva dzose kuti aongorore kushanda kwetsvo dzako uye anogona kukutanga pamuyero wakaderera kana uine matambudziko eitsvo. Mashoko akanaka ndewekuti azathioprine kazhinji haina kuoma pamatsvo kupfuura mamwe mishonga yekudzivirira immune.

Kana uine chirwere cheitsvo chakakomba kana uri pa dialysis, chiremba wako achashanda pedyo nenyanzvi dzeitsvo kuti ave nechokwadi chekuti azathioprine yakachengeteka uye inoshanda kwauri. Vanogona kuda kugadzirisa nguva yemadosi ako kutenderedza zvikamu zve dialysis.

Ndoita Sei Kana Ndakatora Azathioprine Yakawandisa Netsaona?

Kana iwe netsaona ukatora azathioprine yakawanda kupfuura yakarairwa, taura nachiremba wako kana nzvimbo yekudzora chepfu nekukasira, kunyangwe ukanzwa zvakanaka. Kutora zvakanyanya kunogona kudzvinyirira immune system yako kupfuura zvaitarisirwa kana kukonzera mamwe matambudziko akakomba.

Usaedze kugadzirisa muyero wekuwedzera nekusvetuka muyero wako unotevera wakarongeka. Pane kudaro, tevera mirairo yachiremba wako nezvekuti ungadzokera riini kuhurongwa hwako hwakajairika.

Zviratidzo zvekutora azathioprine yakawanda zvinogona kusanganisira kusvotwa kwakanyanya, kurutsa, manyoka, kana kuneta kusinganzwisisike. Kana iwe ukaona chero zviratidzo izvi mushure mekutora mushonga wekuwedzera, tsvaga rubatsiro rwekurapa nekukurumidza.

Kuti udzivise overdoses netsaona, funga kushandisa murongi wepiritsi kana kumisikidza zviyeuchidzo pafoni yako. Chengeta mushonga wako mumudziyo wawo wekutanga uine mavara akajeka, uye usambofa wakatora madosi ekuwedzera kuti "ubate" kana wakanganisa avo vakapfuura.

Ndoita Sei Kana Ndikakanganisa Dose yeAzathioprine?

Kana ukakanganwa kutora mushonga weazathioprine, utore paunorangarira, kunze kwekunge yava nguva yekutora imwe dose. Kana zvakadaro, siya dose yawakakanganwa uye rambira nechirongwa chako chemazuva ose.

Usambofa wakatora madosi maviri panguva imwe chete kuti ugadzirise dose yawakakanganwa, nekuti izvi zvinogona kuwedzera njodzi yako yezvinetso. Kana uchikanganwa madosi kakawanda, taura nachiremba wako nezve nzira dzekukubatsira kurangarira kana kugadzirisa chirongwa chako chekushandisa mushonga kungabatsira.

Kukanganwa madosi dzimwe nguva kazhinji hakuna njodzi, asi kugara uchikanganwa madosi kunogona kuderedza kushanda kwemushonga uye zvinogona kukonzera kuparara kwehutano hwako. Kana wakakanganwa madosi akati wandei, taura nachiremba wako kuti uwane gwara rekuti ungadzokera sei pakutora mushonga zvakachengeteka.

Ndingamira Rini Kutora Azathioprine?

Sarudzo yekumisa azathioprine inofanira kugara ichiitwa nekurairwa nachiremba wako, nekuti kumira kamwe kamwe kunogona kukonzera kuti hutano hwako huparare. Chiremba wako anowanzo kuda kuderedza dose zvishoma nezvishoma pane kumisa zvese kamwechete.

Kune zvirwere zvemuviri zvinorwisa muviri, unogona kumisa azathioprine kana chirwere chako chagara chakanaka kwenguva yakareba, kazhinji mwedzi yakati wandei kusvika kumakore. Zvisinei, vamwe vanhu vanoda kuramba vachishandisa mushonga kwenguva refu kudzivirira kudzoka kwechirwere.

Varwere ve transplant vanowanzo kuda kuramba vachishandisa mishonga inodzvinyirira immune system, kusanganisira azathioprine, kwehupenyu hwese kudzivirira kurambwa kwenhengo. Kunyangwe iwe uchinzwa uine hutano hwakakwana, kumisa mishonga iyi kunogona kuisa nhengo yako yakaiswa panjodzi huru.

Chiremba wako achafunga nezvezvinhu zvakaita sekuti wagara uine hutano hwakanaka kwenguva yakareba sei, hutano hwako hwese, uye chimiro chechirwere chako paachifunga kana zvakachengeteka kuderedza kana kumisa azathioprine. Vachataurawo nezve zviratidzo zvekuchenjerera zvekutarisa kana ukamisa mushonga.

Ndinganwa Doro Here Ndichitora Azathioprine?

Zvakanaka kuderedza kunwa doro paunenge uchitora azathioprine, nekuti mushonga nedoro zvinogona kukanganisa chiropa chako. Kunwa doro rakawanda nguva dzose kunogona kuwedzera njodzi yematambudziko echiropa kana zvichibatanidzwa neazathioprine.

Kunwa doro zvishoma dzimwe nguva kunowanzo gamuchirwa kune vanhu vazhinji, asi unofanira kukurukura mamiriro ako chaiwo nachiremba wako. Vanogona kukupa zano zvichienderana nekushanda kwechiropa chako, mamwe mishonga yaunotora, uye hutano hwako hwese.

Kana ukasarudza kunwa doro, ita izvozvo zvine mwero uye teerera kuti unonzwa sei. Vamwe vanhu vanoona kuti doro rinovakanganisa zvakanyanya vachitora azathioprine, zvichikonzera kuneta kwakawedzerwa kana kusvotwa.

Chiremba wako achatarisa kushanda kwechiropa chako nguva dzose kuburikidza nemiedzo yeropa, zvisinei nekunwa kwako doro. Vaudze chokwadi nezve tsika dzako dzekunwa kuti vakwanise kukupa hanya yakanakisisa uye kutarisisa mamiriro ako.