Chii chinonzi Basiliximab: Zvazvinoshandiswa, Mishonga, Mativi eMuviri, nezvimwe

Basiliximab mushonga wakakosha unoshandiswa kudzivirira muviri wako kubva pakuramba nhengo yakaiswa, kunyanya itsvo. Inopiwa kuburikidza neIV (intravenous) mutsetse zvakananga muropa rako, kazhinji muchipatara pamberi uye mushure mekuvhiyiwa kwako kwekutamisa.

Mushonga uyu ndeweboka rinonzi immunosuppressants, iro rinoshanda nekudzikamisa mhinduro yemuviri wako kune nhengo itsva. Funga nezvazvo sekubatsira muviri wako kugamuchira itsvo yayo itsva seshamwari panzvimbo pemupambi wekunze anoda kurwiswa.

Chii chinonzi Basiliximab?

Basiliximab ndeye antibody yakagadzirwa murabhoritari inonyanya kutariswa maseru emuviri wako. Yakagadzirirwa kutevedzera ma antibodies echisikigo asi nebasa rakanyanya - kudzivirira kurambwa kwenhengo mushure mekuiswa kwetsvo.

Mushonga ndizvo zvinodaidzwa nachiremba kuti

Chikwata chako chekutapurira chichashandisa basiliximab sechinonzi "kurapa kwekutanga." Izvi zvinoreva kuti chinopihwa pakutanga chaipo rwendo rwako rwekutapurira kuti chipe dziviriro yakasimba, yakananga pakarepo kana njodzi yako yekurambwa iri pamusoro. Mushonga uyu unogara uchishandiswa pamwe chete nemimwe mishonga inodzvinyirira immune system yakaita se cyclosporine, mycophenolate, uye corticosteroids.

Mune dzimwe nguva, vanachiremba vanogona kushandisawo basiliximab pakutapurira chiropa, kunyangwe izvi zvisingawanzoitiki. Sarudzo yekushandisa mushonga uyu inoenderana nezvinhu zvako zvaunotarisirwa, hutano hwako hwese, uye mitemo yenzvimbo yako yekutapurira.

Basiliximab Inoshanda Sei?

Basiliximab inoshanda nekudzivisa kwenguva pfupi maseru eimmune akasarudzika anonzi activated T-lymphocytes kubva pakurwisa itsvo yako yakatapurirwa. Inoonekwa seyakati wandei immunosuppressant inopa dziviriro yakatarwa pasina kuvhara zvachose immune system yako.

Paunogamuchira itsvo itsva, immune system yako inozviziva zvakasikwa setishu yekune imwe nyika uye inoda kuiparadza. Basiliximab inonamatira kune receptors paT-maseru ayo anowanzo kuronga kurwisa uku, zvichinyatsoisa maseru aya pakuzorora kwemavhiki akati wandei.

Mushonga haukuvadzi zvachose maseru ako eimmune - unongovadzivisa kubva pakuve akanyatso shandiswa kurwisa nhengo yako itsva. Izvi zvinopa muviri wako nguva yekujairira kutapurira apo mamwe mishonga yenguva refu inotanga kushanda. Iko kudzivisa kunowanzo gara kwemavhiki 4-6, izvo zvinovhara nguva yakakosha yekurambwa kwekutanga.

Ndingatora Sei Basiliximab?

Basiliximab inogara ichipihwa nevashandi vehutano kuburikidza neIV line muruoko rwako kana central catheter. Hauzive kutora mushonga uyu kumba - unoda kutarisirwa zvakanaka muchipatara kana kiriniki ine midziyo yakakodzera yekutarisa.

Mushonga uyu unosanganiswa nemvura yemunyu isina utachiona uye unopiwa zvishoma nezvishoma kwemaminitsi 20-30. Chikwata chako chehutano chichakutarisa zvakanyanya panguva uye mushure mekuiswa kwega kwega kuti uone kuti hauna chero maitiro ekukurumidza. Haufaniri kutsanya kana kudzivisa kudya usati wapiwa basiliximab.

Vanhu vazhinji vanogamuchira mushonga wavo wekutanga mukati memaawa maviri vasati vavhiyiwa kutamiswa kwavo kunotanga. Mushonga wechipiri unowanzo piwa mazuva mana mushure mekutamiswa, kunyangwe chiremba wako angachinja nguva iyi zvichienderana nekupora kwako uye chero matambudziko.

Ndingatora Basiliximab Kwenguva Yakareba Sei?

Varwere vazhinji vanogamuchira basiliximab kwenguva pfupi - kazhinji madosi maviri chete anopiwa mazuva mana akasiyana. Mushonga wekutanga unopiwa usati wavhiyiwa kutamiswa kwako, uye mushonga wechipiri unopiwa pazuva rechina mushure mekutamiswa kwako.

Kusiyana nemimwe mishonga yako yekutamiswa yaunozotora zuva nezuva muhupenyu hwako hwese, basiliximab yakagadzirirwa kupa dziviriro yenguva pfupi, yakasimba panguva yenguva ine njodzi yakanyanya. Mushure memadosi ako maviri, hauzogamuchiri basiliximab zvakare, asi ucharamba uchitora mimwe mishonga yako yekudzivirira immune sezvakanyorwa.

Mhedzisiro ye basiliximab inoramba ichishanda mumuviri wako kwemavhiki akati wandei mushure memushonga wako wekupedzisira. Dziviriro iyi yakawedzerwa inobatsira kuvhara mukaha apo mimwe mishonga yako inosvika pakushanda kwayo kwakazara uye muviri wako unochinjika kune itsvo itsva.

Ndezvipi Zvipingamupinyi zveBasiliximab?

Vanhu vazhinji vanotsungirira basiliximab zvakanaka, asi semishonga yese, inogona kukonzera mhedzisiro. Mashoko akanaka ndewekuti maitiro akakomba haawanzoitiki, uye chikwata chako chehutano chichakutarisa zvakanyanya panguva yekurapa.

Heano mhedzisiro yakajairika yaungasangana nayo, uye yeuka kuti zhinji dzeizvi dzinogonawo kuve dzichibatanidzwa nekuvhiyiwa kwako kutamiswa kana mimwe mishonga yaunotora:

• Kutemwa nemusoro nekuneta kwese
• Kunzwa kuda kurutsa kana dumbu kusagadzikana
• Manyoka kana kuvharika mudumbu
• Kuzvimba mumaoko ako, tsoka, kana makumbo
• Kutadza kurara
• Kutenderera kana kunzwa musoro uchirwadza
• Kurwadziwa kana kunzwa munzvimbo yekubaiwa jekiseni

Zviratidzo izvi zvinowanzoita zvinyoro uye zvenguva pfupi. Chikwata chako chekutapurirana chinogona kukubatsira kudzora kusagadzikana chero kupi nekuchengetedza uye kugadzirisa mishonga yako imwe kana zvichidikanwa.

Vamwe vanhu vanogona kusangana nemigumisiro yakakomba inoda kutariswa kwekurapa nekukurumidza. Izvi hazviwanzoitiki asi zvakakosha kuziva:

• Zviratidzo zvekuita allergic senge rash, kukwenya, kana kutadza kufema
• Kuzvimba kwakanyanya kwechiso, miromo, rurimi, kana huro
• Kubuda ropa kusinganzwisisike kana kupwanya
• Zviratidzo zvehutachiona senge fivha, kutonhora, kana kurwadziwa kwehuro
• Kurwadziwa mudumbu kwakanyanya kana kurutsa kusingaperi
• Kurwadziwa muchipfuva kana kurova kwemoyo kusingaite

Kana ukaona chero zviratidzo izvi, taura nechikwata chako chekutapurirana nekukurumidza. Vakashongedzerwa kukubatsira kuziva kana zviratidzo zvine chekuita nebasiliximab kana zvimwe zvezvako zvekutariswa.

Ndiani Asingafaniri Kutora Basiliximab?

Basiliximab haina kukodzera munhu wese, uye chikwata chako chekutapurirana chichanyatsoongorora nhoroondo yako yekurapa usati waikurudzira. Haufanirwe kugamuchira mushonga uyu kana uine allergic ku basiliximab kana chero zvikamu zvaro.

Vanhu vane hutachiona hunoshanda, hunokosha vanowanzoita kuti vave nazvo vasati vagamuchira basiliximab. Sezvo mushonga uchiisa pasi immune system yako, unogona kuita kuti hutachiona huripo huwedzere kana kuoma kurapa.

Chiremba wako achafungawo basiliximab zvakanyatso kana uine nhoroondo yegomarara, kunyanya magomarara eropa senge lymphoma. Kunyange mushonga usingakonzeri gomarara zvakananga, unogona kuwedzera njodzi yako nekudzora immune surveillance.

Vakadzi vane pamuviri vanoda kutariswa zvakanyanya, nekuti basiliximab inopfuura placenta uye inogona kukanganisa mwana ari kukura. Kana iwe uri nepamuviri kana kuronga kuva nepamuviri, kurukurai izvi zvakadzama nechikwata chako chekutapurirana kuti uenzanise njodzi nemabhenefiti.

Mazita eBasiliximab Brand

Basiliximab inowanikwa zvakanyanya pasi pezita rekuti Simulect, rinogadzirwa neNovartis. Iyi ndiyo fomu inoshandiswa zvakanyanya muzvipatara uye nzvimbo dzekutapurirana pasi rese.

Kusiyana nemimwe mishonga ine mazita akawanda emhando, basiliximab ine shanduko shoma dzemhando nekuti mushonga wakakosha webiologic unoshandiswa munzvimbo dzakakosha dzekurapa. Pharmacy yako yechipatara inowanzo chengeta Simulect, kunyangwe vachigona kushandisa shanduro dzakajairika kana dziripo.

Paunenge uchikurukura kurapwa kwako nevapi vehutano, unogona kuvazwa vachitaura nezve

Chikwata chako chekutapurirana chinogonawo kufunga kushandisa madosi akakwirira eanowanzo immunosuppressants senge tacrolimus kana mycophenolate panzvimbo yeinduction therapy, zvichienderana neako ega njodzi profile uye nzvimbo protocols.

Ko Basiliximab Zviri Nani Kupfuura Antithymocyte Globulin?

Ose ari maviri basiliximab uye antithymocyte globulin (ATG) anobudirira induction therapies, asi anoshanda zvakasiyana uye anokodzera mamiriro akasiyana emurwere. Basiliximab inowanzoita kuti pave nemigumisiro mishoma uye inowanzoita nyore kutsungirira.

ATG inopa yakakura uye yakanyanya immunosuppression, iyo inogona kubatsira varwere vane njodzi huru yekurambwa. Zvisinei, inowedzerawo njodzi yekutapukirwa uye mamwe matambudziko nekuti inodzvinyirira immune system zvakanyanya.

Basiliximab inopa yakatarwa immune kudzvinyirira ine njodzi yakaderera yekutapukirwa kwakakomba uye mamwe matambudziko. Izvi zvinoita kuti ive sarudzo yakanaka yevashandi vane njodzi yakajairika vasingade kudzvinyirira kwakanyanya kunopiwa neATG.

Chikwata chako chekutapurirana chichafunga nezvezvinhu zvakaita sezera rako, hutano hwese, basa reitsvo, uye zvinhu zvakakosha zvenjodzi pakusarudza pakati pezvisarudzo izvi. Hapana mushonga wakanyanya

Sezvo basiliximab ichipiwa nenyanzvi dzehutano munzvimbo inodzorwa, kuwandisa kwemishonga netsaona hakusi kwakajairika. Mishonga inopiwa zvine hungwaru zvichienderana nehuremu hwemuviri wako uye inopiwa zvishoma nezvishoma pasi pekutariswa kwechiremba.

Kana uine hanya nezvehuwandu hwaunogamuchira, taura nechikwata chako chekutapurirana nekukasira. Vanogona kuongorora marekodhi ako ekupa mishonga uye kukutarisa chero zviratidzo zvisingajairiki. Hapana mushonga chaiwo we basiliximab, saka kurapwa kwaizotarisa pane kutarisirwa kunotsigira kana zvichidikanwa.

Ndoita Sei Kana Ndikakanganwa Dose yeBasiliximab?

Kukanganwa dose ye basiliximab kunonetesa nekuti mishonga inopiwa pane chirongwa chakanyatsojeka kuchengetedza itsvo yako yakatapurirwa. Bata chikwata chako chekutapurirana nekukasira kana ukakanganwa dose yako yechipiri yakarongwa.

Vanachiremba vako vachada kuongorora kuti zvatora nguva yakareba sei kubva pa dose yako yakakanganwa uye kana zvichiri kubatsira kuipa. Vanogona kugadzirisa mamwe ako emishonga yekudzivirira immune kuti vatsive dose ye basiliximab yakakanganwa.

Ndingamira Rini Kutora Basiliximab?

Haufanire kunetseka nezvekumira basiliximab nekuti inongopiwa kaviri panguva yekutapurirana kwako. Mushure memadosi ako maviri akarongwa, hauzogamuchiri imwe basiliximab.

Mhedzisiro yemishonga ichapera zvishoma nezvishoma kwemavhiki akati wandei, izvo zviri chikamu chechirongwa chekurapa chinangwa. Mamwe ako emishonga yekudzivirira immune achaenderera mberi nekupa dziviriro sezvo mhedzisiro ye basiliximab ichipera.

Ndingagamuchira Majekiseni Ndiri Kutora Basiliximab?

Majekiseni mhenyu anofanira kudziviswa apo basiliximab ichishanda mumuviri wako uye mukati mekurapwa kwako kwekutapukira. Izvi zvinosanganisira majekiseni seMMR, varicella, uye majekiseni eflu emumhino.

Majekiseni asina simba (akaita semajekiseni e furu, majekiseni e pneumonia, uye majekiseni e COVID-19) anowanzo chengeteka uye anokurudzirwa, kunyangwe angasashanda zvakanaka apo immune system yako yakadzvanywa. Chikwata chako che transplant chichakutungamira panguva yakanakisa yekuti utore majekiseni api ese aunoda.