Chii chinonzi Bictegravir-Emtricitabine-Tenofovir Alafenamide: Zvinoshandiswa, Mishonga, Migumisiro Yemuviri uye Zvimwe

Bictegravir-emtricitabine-tenofovir alafenamide mushonga weHIV unosanganisa unobatsira kuchengetedza hutachiona mumuviri wako. Iri piritsi rimwe chete rinosanganisa mishonga mitatu ine simba inoshanda pamwe chete kudzivirira HIV kubva pakuzviparadzanisa nekupararira mumuviri wako wese. Ungangoziva mushonga uyu nezita rawo rekutengesa Biktarvy, uye wakagadzirirwa kuita kuti kurapwa kweHIV kuve nyore nekugadzira zvese zvaunoda mune piritsi rimwe rezuva nezuva.

Chii chinonzi Bictegravir-Emtricitabine-Tenofovir Alafenamide?

Mushonga uyu ipiritsi rine zvitatu-mu-imwe rinorapa hutachiona hweHIV. Piritsi rega rega rine bictegravir (50mg), emtricitabine (200mg), uye tenofovir alafenamide (25mg) vachishanda sechikwata kurwisa hutachiona. Funga nezvazvo sekunge uine makiyi matatu akasiyana pamusuwo wako - chimwe nechimwe chinovhara HIV nenzira yakasiyana, zvichiita kuti zvinyanye kuomera hutachiona kukonzera matambudziko.

Nzira yekusanganisa zvinoreva kuti unongoda kutora piritsi rimwe chete zuva rega rega panzvimbo yemishonga yakawanda yakaparadzana. Izvi zvinoita kuti zvive nyore kunamatira kuronga kwako kurapwa uye kunoderedza mukana wekusavapo kwemishonga. Chiremba wako anowanzo kunyora izvi sechikamu chechirongwa chakazara chekurapa HIV.

Chii chinonzi Bictegravir-Emtricitabine-Tenofovir Alafenamide chinoshandiswa?

Mushonga uyu unorapa hutachiona hweHIV-1 muvanhu vakuru nevana vanorema angangoita makirogiramu makumi maviri nemashanu (anenge mapaundi makumi mashanu nemashanu). Inoshandiswa kune vanhu vari kungotanga kurapwa kweHIV uye avo vanoda kuchinja kubva kune mamwe mishonga yeHIV. Chinangwa ndeche kuderedza huwandu hweHIV muropa rako kusvika kumazinga asinganzwisisike, izvo zvinodzivirira immune system yako uye zvinodzivirira kupararira kune vamwe.

Vanachiremba vanowanzo nyora mushonga uyu nekuti unoshanda zvakanyanya uye unotsungirirwa zvakanaka. Zvinonyanya kubatsira vanhu vanoda kurerutsa maitiro avo emishonga kana avo vakawana matambudziko nemamwe marapirwo eHIV. Murapi wako wehutano achasarudza kana musanganiswa uyu wakakodzera mamiriro ako chaiwo.

Bictegravir-Emtricitabine-Tenofovir Alafenamide Inoshanda Sei?

Mushonga uyu unoshanda nekudzivisa HIV pazvikamu zvakasiyana zveupenyu hwayo. Bictegravir is integrase inhibitor inodzivirira HIV kubva pakupinza zvinhu zvayo zvemajini mumasero ako ane hutano. Emtricitabine uye tenofovir alafenamide ese ari nucleoside reverse transcriptase inhibitors anodzivirira HIV kubva pakugadzira makopi ayo.

Pamwe chete, izvi zvitatu zvinogadzira chipingamupinyi chakasimba kurwisa kuwanda kweHIV. Kana hutachiona husingakwanise kubereka zvakare, huwandu hweHIV muropa rako hunoderera zvakanyanya. Izvi zvinoonekwa semusanganiswa wemishonga yakasimba nekuti inorwisa HIV nenzira dzakawanda panguva imwe chete, zvichiita kuti zvive zvakaoma kuti hutachiona hukure kuramba.

Mishonga haiporesi HIV, asi inogona kuderedza hutachiona kusvika pamatanho asinganzwisisike muropa rako. Kana HIV isinganzwisisike, zvinoreva kuti haugone kutapurira hutachiona kune vadyidzani vepabonde, uye immune system yako inogona kupora uye kuramba iine hutano.

Ndinofanira Kutora Sei Bictegravir-Emtricitabine-Tenofovir Alafenamide?

Tora piritsi rimwe nemuromo kamwe pazuva, uine kana pasina chikafu. Unogona kuitora nemvura, muto, kana mukaka - chero zvinoita sekunyaradza kwauri. Edza kuitora panguva imwe chete zuva rega rega kuti ikubatsire kuyeuka uye kuchengetedza mazinga akagadzikana emishonga mumuviri wako.

Haufaniri kudya usati watora mushonga uyu, asi vamwe vanhu vanoona zviri nyore mudumbu ravo kana vakatora vaine chikafu. Kana ukaona kusagadzikana mudumbu, edza kuutora nechikafu chidiki kana chikafu. Medza piritsi rose - usapwanye, utaune, kana kuripwanya, sezvo izvi zvinogona kukanganisa mashandiro emushonga.

Kana ukatora antacids, calcium supplements, kana iron supplements, zviise zvakasiyana neawa 2 kubva kumushonga uyu. Izvi zvinogona kukanganisa mashandiro emuviri wako ekutora mushonga weHIV. Murapi wako wemishonga anogona kukubatsira kuronga nguva yakanaka yemishonga yako yese.

Ndinofanira Kutora Bictegravir-Emtricitabine-Tenofovir Alafenamide Kwenguva Yakareba Sei?

Unofanira kutora mushonga uyu kwenguva isingagumi kuti uchengetedze HIV pasi pekutonga. Kurapa HIV ibasa reupenyu hwese, uye kumisa mushonga kunobvumira hutachiona kuti huwedzere zvakare nekukurumidza. Vanhu vazhinji vanoramba vachitora mushonga uyu kwemakore, chero uchiramba uchishanda uye uchitsungirirwa zvakanaka.

Chiremba wako achatarisa kufambira mberi kwako nekuongororwa kweropa nguva dzose kuti aongorore viral load yako uye CD4 cell count. Miedzo iyi inobatsira kuona kuti mushonga uri kushanda sei. Kana viral load yako ikava isingaonekwe uye ikaramba yakadaro, chiratidzo chekuti mushonga uri kuita basa rawo nemazvo.

Usambomira kutora mushonga uyu usati wataura nachiremba wako kutanga. Kunyangwe ukanzwa uine hutano hwakakwana, mushonga ndiyo iri kuchengetedza hutachiona hwakadzvanywa. Chikwata chako chehutano chichashanda newe kuti chigadzirise chero zvinokunetsa uye chive nechokwadi chekuti unogona kuramba kurapwa zvakabudirira.

Ndezvipi Zvakaipa ZveBictegravir-Emtricitabine-Tenofovir Alafenamide?

Vanhu vazhinji vanotsungirira mushonga uyu zvakanaka, asi semishonga yese, inogona kukonzera mhedzisiro. Mashoko akanaka ndeokuti mhedzisiro yakakomba haisi yakajairika, uye vanhu vazhinji vanowana matambudziko mashoma kana asipo vachiiutora.

Heano mhedzisiro yakajairika yaungasangana nayo, kunyangwe vanhu vazhinji vasina chero nyaya idzi:

• Kutemwa nemusoro
• Manyoka
• Kunzwa kusvotwa
• Kuneta kana kunzwa kuneta
• Kutenderera musoro
• Kutadza kurara
• Kurota zvisinganzwisisike

Mhedzisiro iyi inowanzoita nyoro uye inowanzoita nani mukati memavhiki mashoma ekutanga sezvo muviri wako uchigadzirisa mushonga. Kana vachiramba kana kukutambudza, taura nemupi wako wezvehutano nezve nzira dzekuvagadzirisa.

Dzimwe mhedzisiro dzisingawanzoitiki asi dzakakomba dzinoda kutariswa kwekurapa nekukurumidza. Kunyangwe izvi zvichishamisa, zvakakosha kuzviziva:

• Kushungurudzika kwakanyanya kana pfungwa dzekuzviuraya
• Matambudziko akakomba eitsvo (kuderera kwemvura, kuzvimba, kuvhiringidzika)
• Matambudziko emapfupa (kurwadziwa kwemapfupa kusinganzwisisike, mapfupa akaputsika)
• Matambudziko echiropa (kuita yero kweganda kana maziso, weti yakasviba, kurwadziwa kwakanyanya mudumbu)
• Lactic acidosis (kurwadziwa kwemhasuru kusinganzwisisike, kutadza kufema, kurwadziwa mudumbu, kutenderera musoro)

Bata chiremba wako nekukurumidza kana uine chero zviratidzo izvi zvakakomba. Kunyangwe zvisingawanzoitiki, kuziva nekutanga kurapwa kwakakosha kuchengetedzeka kwako uye kugara zvakanaka.

Ndiani Asingafaniri Kutora Bictegravir-Emtricitabine-Tenofovir Alafenamide?

Mushonga uyu hauna kukodzera munhu wese, uye chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akuraira. Hauzofaniri kutora mushonga uyu kana uine allergic kune chero zvinhu zvawo kana kana uine chirwere chakakomba cheitsvo.

Vanhu vane mamwe mamiriro ehutano vanoda kuongororwa kwakakosha kana vangangoda kushandisa mumwe mushonga weHIV panzvimbo. Chiremba wako achanyatso chenjerera kana uine:

• Chirwere cheitsvo kana kuderedzwa kwekuita kweitsvo
• Chirwere chechiropa, kusanganisira hepatitis B kana C
• Matambudziko emapfupa kana nhoroondo yemapfupa akaputsika
• Kushungurudzika kana mamwe mamiriro ehutano hwepfungwa
• Chirwere chemoyo

Kana uine hepatitis B, kumisa mushonga uyu kamwe kamwe kunogona kukonzera hepatitis yako kuti itange zvakanyanya. Chiremba wako achakutarisa zvakanyanya uye anogona kuda kunyora mishonga yekuwedzera kuchengetedza chiropa chako.

Vakadzi vane pamuviri vanogona kutora mushonga uyu, asi zvakakosha kukurukura njodzi nemabhenefiti nachiremba wako. Mushonga unogona kupinda mumukaka wemazamu, saka sarudzo dzekuyamwisa dzinofanirwa kuitwa nekuchenjerera nekutungamirirwa kwekurapa.

Bictegravir-Emtricitabine-Tenofovir Alafenamide Zita reBrand

Zita rebrand remushonga uyu mubatanidzwa ndiBiktarvy. Inogadzirwa neGilead Sciences uye yakatenderwa neFDA muna 2018. Unogona kuona mushonga uyu uchinzi nezita rebrand kana zvikamu zvaro zvakajairika.

Biktarvy inowanikwa sepiritsi repurple, rakaita oval rine

Mhando dzese dzemishonga idzi dzinobatsira zvikuru pakudzora HIV, uye sarudzo yakanaka zvinoenderana nemamiriro ako ega. Marongerwo emishonga ane bictegravir-based akadai seBiktarvy uye marongerwo emishonga ane dolutegravir-based akadai seTriumeq ese anoonekwa semishonga yekutanga nemirairo yekurapa HIV.

Biktarvy inogona kuva nezvimwe zvakanakira maererano nekudyidzana kwemishonga kushoma uye pamwe kuwedzera uremu kushoma kana ichienzaniswa nemamwe marongerwo emishonga ane dolutegravir-based. Zvisinei, misanganiswa ine dolutegravir-based yakashandiswa kwenguva refu uye ine ruzivo rwakawanda rwechokwadi. Zvese zviri zviviri zvisarudzo zvakanaka kune vanhu vazhinji vari kutanga kurapwa kweHIV.

Chiremba wako achafunga nezvezvinhu zvakaita semimwe mishonga yako, mamiriro ehutano, uye zvaunofarira pachako paunenge uchisarudza pakati pezvisarudzo izvi. Marongerwo ese ane kubudirira kwakanyanya pakuwana nekuchengetedza mitoro yevirus isingaonekwe.

Mibvunzo Inowanzo Bvunzwa Nezve Bictegravir-Emtricitabine-Tenofovir Alafenamide

Q1. Bictegravir-Emtricitabine-Tenofovir Alafenamide Yakachengeteka Kune Vanhu Vane Chirwere Cheitsvo Here?

Mushonga uyu unogona kushandiswa kune vanhu vane chirwere cheitsvo chinyoro kusvika pakati nepakati, asi zvinoda kutariswa zvakanyanya. Chiremba wako achaongorora basa reitsvo yako nguva dzose nemiedzo yeropa uye anogona kugadzirisa chirongwa chako chekurapa kana zvichidikanwa. Vanhu vane chirwere cheitsvo chakakomba (creatinine clearance isingasviki 30 mL/min) havafaniri kutora mushonga uyu.

Chikamu chetenofovir alafenamide chiri nyore pamapapu pane mafomu ekare e tenofovir, zvichiita kuti musanganiswa uyu uve sarudzo yakanaka kune vanhu vazhinji vane hanya neitsvo. Zvisinei, mupi wako wehutano achayeresa zvakanakira nenjodzi zvichienderana nebasa rako reitsvo.

Q2. Ndingaita Sei Kana Ndikatora Bictegravir-Emtricitabine-Tenofovir Alafenamide zvakanyanya netsaona?

Kana ukangoerekana watora piritsi rinopfuura rimwe chete pazuva, taura nachiremba wako kana muzvinabhuku kuti uwane zano. Kutora imwe dose nguva nenguva hazvingakonzere kukuvadza zvakanyanya, asi zvakakosha kuwana gwara rekurapa. Usaedze "kugadzirisa" dose yakawedzerwa nekusvetuka dose yako inotevera yakarongwa.

Kana wakatora zvakawanda zvakanyanya kupfuura zvakarairwa kana kunzwa usina kunaka mushure mekutora mushonga wakawedzerwa, tsvaga kutariswa kwekurapa nekukurumidza. Chengeta rekodhi rekuti wakatora riini uye zvakadii kuti ubatsire vanopa hutano kukupa zano rakanaka.

Q3. Ndingaita Sei Kana Ndikakanganwa Dose yeBictegravir-Emtricitabine-Tenofovir Alafenamide?

Kana ukakanganwa dose, itore paunorangarira zuva rimwe chetero. Kana yava nguva yechikamu chako chinotevera (mukati me12 maawa), svetuka dose yakakanganwa uye tora dose yako inotevera yakarongwa. Usambofa wakatora madosi maviri panguva imwe chete kuti ugadzirise dose yakakanganwa.

Edza kudzokera pachirongwa chako chetsika nekukurumidza sezvinobvira. Kukanganwa madosi nguva nenguva hakuzokonzeri matambudziko nekukurumidza, asi kukanganwa madosi nguva dzose kunogona kubvumira HIV kuti ivake kuramba mushonga. Funga nezvekuseta zviyeuchidzo zvefoni kana kushandisa murongi wepiritsi kuti akubatsire kurangarira.

Q4. Ndingamira Rini Kutora Bictegravir-Emtricitabine-Tenofovir Alafenamide?

Haufanire kumira kutora mushonga uyu usati wataura nachiremba wako kutanga. Kurapa HIV ndekwehupenyu hwese, uye kumisa mushonga kunobvumira hutachiona kuti huwedzere zvakare nekukurumidza. Kunyangwe kana mutoro wako wehutachiona usingaonekwe uye uchinzwa uine hutano, mushonga ndiyo iri kuchengetedza hutachiona hwakadzvanywa.

Chiremba wako angangofunga nezvekuchinja mushonga wako kana uine mhedzisiro kana kana mamwe mamiriro ehutano akaitika, asi izvi zvingabatanidza kuchinjira kune imwe HIV regimen pane kumisa kurapwa zvachose. Chinangwa ndechinogara chiri kuchengetedza kudzvinyirirwa kweHIV kunoshanda.

Q5. Ndinganwa Doro Ndiri Kutora Bictegravir-Emtricitabine-Tenofovir Alafenamide?

Kunwa doro zvine mwero kazhinji kwakanaka uchitora mushonga uyu, asi zvakanaka kukurukura tsika dzako dzekunwa nedhokotera wako. Doro harina hukama zvakananga nemishonga iyi yeHIV, asi kunwa zvakanyanya kunogona kukanganisa chiropa chako uye hutano hwako hwese.

Kana uine matambudziko echiropa, kusanganisira hepatitis B kana C, chiremba wako anogona kukurudzira kuderedza kana kudzivisa doro zvachose. Rangarira kuti kugara uine hutano hwakanaka zvinobatsira kurapwa kwako kweHIV kushanda zviri nani uye kunoderedza njodzi yematambudziko.