Chii chinonzi Buprenorphine: Kushandiswa, Dosages, Side Effects uye Zvimwe

Buprenorphine mushonga unopiwa nachiremba unobatsira kudzora kurwadziwa kwakanyanya uye kurapa kupindwa muropa neopioid. Iyo ndeyeboka remishonga inonzi partial opioid agonists, zvinoreva kuti inoshanda zvakasiyana nemamwe maopioid nekupa zororo rekurwadziwa kana kuderedza zviratidzo zvekubvisa pasina kukonzera imwecheteyo njodzi yekuvimba.

Mushonga uyu unouya mumhando dzakawanda, kusanganisira mahwendefa anonyungudika pasi perurimi rwako (sublingual) kana kurwisa matama ako (buccal). Iyi nzira dzakakosha dzekutumira dzinobatsira mushonga kunyudzwa zvakananga muropa rako kuburikidza nemaseru mumuromo mako, zvichiita kuti ushande nekukurumidza uye nekukurumidza kupfuura mapiritsi aunomedza.

Chii chinonzi Buprenorphine chinoshandiswa?

Buprenorphine inoshanda zvinangwa zviviri mukurapa kwekurapa. Kutanga, inobatsira vanhu kudzora kurwadziwa kwakanyanya, kusingaperi kana mamwe marwadzo emishonga asina kushanda zvakanaka zvakakwana. Chechipiri, inotamba basa rakakosha mukurapa opioid kushandiswa disorder nekuderedza zvishuwo uye zviratidzo zvekubvisa.

Kuti utarise kurwadziwa, vanachiremba vanowanzo nyora buprenorphine kana iwe uchida zororo rekurwadziwa nguva dzose yezvinhu zvakaita sekenza, arthritis yakanyanya, kana kurwadziwa kwemashure kusingaperi. Mushonga unopa kugadzirisa marwadzo zuva rese, kukubatsira kuchengetedza hupenyu huri nani.

Mukurapa kupindwa muropa, buprenorphine inobatsira vanhu kupora kubva mukuvimba nemaopioid senge heroin, mishonga yekurwadziwa yakanyorwa, kana fentanyl. Inoderedza zviratidzo zvisingafadzi zvekubvisa uye inoderedza zvishuwo, zvichiita kuti zvive nyore kutarisa pakupora uye kuvaka hupenyu hwako patsva.

Buprenorphine inoshanda sei?

Buprenorphine inoshanda nekunamatira kune imwecheteyo uropi receptors ayo mamwe maopioid anotariswa, asi inoita kudaro nenzira yakasiyana. Semuenzaniso weopioid agonist, inoshandisa aya ma receptors zvakakwana kuti ape zororo rekurwadziwa kana kudzivirira zviratidzo zvekubvisa pasina kugadzira kukwirisa kwakanyanya kunobatanidzwa nemamwe maopioid.

Funga nezvazvo sekiyi inokwana mugonhi asi inongotendeuka hafu. Iyi activation isina kukwana inoreva kuti buprenorphine ine "ceiling effect" yekudzora kufema, zvichiita kuti ive yakachengeteka kupfuura full opioid agonists. Kunyangwe ukatora zvakanyanya, hazviite kuti zvikonzere matambudziko ekufema ane njodzi.

Mishonga iyi inoonekwa seyepakati nepakati yakasimba ichienzaniswa nemamwe maopioids. Iyo ine simba kupfuura codeine kana tramadol asi yakagadzirirwa kuve yakachengeteka kupfuura morphine kana oxycodone. Iyi chiyero inoita kuti ive inoshanda pakurapa uku ichideredza njodzi yekunyanyisa.

Ndingatora Sei Buprenorphine?

Nzira yaunotora buprenorphine inoenderana nefomu rakarairwa nachiremba wako. Kune sublingual tablets, isa piritsi pasi perurimi rwako uye rega rinyungudike zvachose usingatsengi kana kumedza. Izvi zvinowanzo tora maminitsi mashanu kusvika gumi.

Kana iwe uchishandisa buccal tablets, isa izvo pamukati mematama ako uye rega zvinyungudike zvishoma nezvishoma. Usadye, kunwa, kana kutaura apo piritsi richinyungudika, sezvo izvi zvinogona kukanganisa kuti mushonga unotora sei mumuviri wako.

Heano mamwe matungamirirwo akakosha ekutevera paunenge uchitora buprenorphine:

• Tora mushonga panguva imwe chete zuva rega rega kuti uchengetedze mazinga akagadzikana mumuviri wako
• Usadya kana kunwa chero chinhu kwemaminitsi gumi nemashanu mushure mekunge piritsi ranyungudika
• Dzivisa kusvuta kana kushandisa zvigadzirwa zvefodya nguva pfupi usati kana mushure mekutora chiyero chako
• Chengeta muromo wako wakanyorova asi usaite mvura usati waisa piritsi
• Kana uchida kutora mapiritsi akawanda, rega rimwe nerimwe rinyungudike zvachose usati watora rinotevera

Unogona kutora buprenorphine uine kana pasina chikafu, asi kuenderana kunobatsira muviri wako kutora mushonga nenzira inotaurwa. Vamwe vanhu vanoona zviri nyore kutora chiyero chavo mangwanani-ngwanani vasati vadya kana kunwa chero chinhu.

Ndingatora Buprenorphine Kwenguva Yakareba Sei?

Kureba kwemushonga we buprenorphine kunosiyana zvakanyanya zvichienderana nekuti uri kuutora nei uye muviri wako unopindura sei. Panyaya yekurapa marwadzo echirwere, unogona kuda kuutora kwemwedzi kana makore, chero uchiramba uchibatsira uye usingakonzeri matambudziko.

Panyaya yekurapa kusvuta zvinodhaka zve opioid, nguva yacho inosiyana zvakanyanya uye inowanzoenda kwemwedzi yakawanda kana makore. Tsvagiridzo inoratidza kuti nguva refu yekurapa inowanzoita kuti pave nemigumisiro iri nani, nevakawanda vachibatsirwa nekurapa kwekuchengetedza kwenguva yakareba.

Chiremba wako achashanda newe kuti aone kureba kwakakodzera kwekurapa zvichienderana nemamiriro ako chaiwo. Vachafunga zvinhu zvakaita semarwadzo ako, kufambira mberi kwekupora, hutano hwako hwese, uye zvinangwa zvako pachako. Usambomira kutora buprenorphine kamwe kamwe usina kutarisirwa nachiremba, nekuti izvi zvinogona kukonzera zviratidzo zvekubvisa zvisingafadzi.

Ndezvipi Zvakaipa zveBuprenorphine?

Semishonga yese, buprenorphine inogona kukonzera mhedzisiro, kunyangwe kwete munhu wese anozviwana. Mazhinji emhedzisiro yacho yakapfava kusvika pakati nepakati uye inowanzoita nani sezvo muviri wako uchigadzirisa kumushonga mumavhiki mashoma ekutanga ekurapa.

Mhedzisiro yakajairika yaungasangana nayo inosanganisira:

• Kutadza kufara uye kurutsa, kunyanya mumazuva mashoma ekutanga
• Musoro uye dzungu
• Kuvharika, izvo zvinogona kutarisirwa nekuchinja kudya uye mvura
• Kuzara kana kunzwa kuneta
• Matambudziko ekurara kana kusarara
• Kutukwa zvakanyanya kupfuura zvakajairika
• Muromo wakaoma kana kunzwa kunyorova panonyungudutswa piritsi

Mhedzisiro iyi yakajairika inowanzoita isinganyanyi kunetsa sezvo muviri wako uchigadzirisa kumushonga. Kunwa mvura yakawanda, kudya chikafu chine fiber yakawanda, uye kuita maekisesaizi akajairika anogona kubatsira kutarisira zvimwe zvezviratidzo izvi.

Panguva iyo isingawanzoitiki, vamwe vanhu vanogona kusangana nemhedzisiro yakakomba inoda kutarisirwa nachiremba:

• Matambudziko makuru ekufema kana kufema zvishoma
• Kurwadziwa muchipfuwa kana kurova kwemoyo kusingaite zvakanaka
• Dizziness yakanyanya kana kupfeka
• Kuvhiringidzika kana kuoma kufunga
• Kurwadziwa mudumbu kwakanyanya kana kurutsa kusingapere
• Zviratidzo zvekuita allergic senge rash, kuita ganda, kana kuzvimba

Kana ukaona chero mhedzisiro yakakomba iyi, taura nemupi wezvehutano wako nekukasira kana kutsvaga rubatsiro rwekurapa rwechimbichimbi. Kuchengeteka kwako ndiko kukosha kukuru, uye zviratidzo izvi hazvifanirwe kufuratirwa.

Ndiani Asingafaniri Kutora Buprenorphine?

Buprenorphine haina kukodzera munhu wese, uye mamwe mamiriro ehutano kana mamiriro anoita kuti isachengeteke kushandisa. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa usati wanyora mushonga uyu kuti uve nechokwadi chekuti wakakodzera kwauri.

Haufanire kutora buprenorphine kana uine:

• Allergy inozivikanwa ku buprenorphine kana chero zvinhu mumushonga
• Matambudziko makuru ekufema kana kuora mwoyo kwekufema
• Kuvharika mudumbu rako kana matumbu
• Chirwere chechiropa chakanyanya kana kutadza kwechiropa
• Wakanga uchimwa doro kana kutora ma sedatives munguva pfupi yapfuura

Mapoka evanhu vanoda kufunga kwakakosha uye kuongororwa zvakanyanya pavanenge vachitora buprenorphine. Chiremba wako achayerera mabhenefiti nenjodzi kana iwe wakazvitakura, uchiyamwisa, wakuru, kana uine matambudziko eitsvo, mamiriro ehutano hwepfungwa, kana nhoroondo yekukuvara kwemusoro.

Vanhu vane sleep apnea, matambudziko ethyroid, kana adrenal gland disorders vanodawo kuongororwa zvakanyanya vasati vatanga kurapwa. Mupi wako wezvehutano achasarudza kana buprenorphine yakachengeteka kumamiriro ako chaiwo.

Mazita eBuprenorphine Brand

Buprenorphine inowanikwa pasi pemazita akati wandei emhando, imwe neimwe yakagadzirirwa kushandiswa kwakakosha uye nzira dzekutumira. Mazita akajairika emhando anosanganisira Suboxone, iyo inobatanidza buprenorphine ne naloxone kudzivirira kushandiswa zvisizvo, uye Subutex, iyo ine buprenorphine chete.

Mamwe mazita emhando yaungasangana nawo anosanganisira Belbuca yekurapa kurwadziwa kusingaperi, Bunavail yekurapa kuvimba neopioid, uye Zubsolv, rimwe mushonga wakasanganiswa. Mhando imwe neimwe ine mafomula akasiyana zvishoma kana masisitimu ekutumira, asi ese ane chinhu chimwe chete chinoshanda.

Chiremba wako achasarudza mhando yakakodzera zvichienderana nezvido zvako, inishuwarenzi, uye zvinangwa zvekurapa. Usachinje pakati pemhando dzakasiyana pasina kubvunza mupi wako wehutano, sezvo vangave vaine mitengo yakasiyana yekutora kana mhedzisiro.

Zvimwe Zvinhu Zviri Panzvimbo yeBuprenorphine

Kune dzimwe nzira dzakawanda dzekurapa kurwadziwa uye kurapwa kwekuvhiya kweopioid, zvichienderana nezvido zvako uye mamiriro ako ekurapa. Chiremba wako achakubatsira kuongorora sarudzo idzi kana buprenorphine isiri yako kana ikamira kushanda nemazvo.

Pakuita manejimendi ekurwadziwa kusingaperi, dzimwe nzira dzinogona kusanganisira mamwe maopioid anogara kwenguva refu se morphine kana oxycodone, mishonga yekurwadziwa isiri yeopioid se gabapentin kana duloxetine, kana nzira dzisiri dzemishonga senge physiotherapy uye cognitive behavioral therapy.

Pakuita manejimendi ekuvhiya kweopioid, dzimwe nzira dzinosanganisira methadone maintenance therapy, naltrexone (mumuromo kana injectable), kana kuraira kwakanyanya uye zvirongwa zvekutsigira. Sarudzo imwe neimwe ine zvakasiyana zvinobatsira uye zvekufunga izvo timu yako yehutano ichakurukura newe.

Nzira yakanakisa yekurapa inowanzo sanganisa mishonga nekupa mazano, mapoka ekutsigira, uye shanduko yehupenyu. Chiremba wako achashanda newe kuti agadzire chirongwa chakazara chekurapa chinotarisana nezvido zvako nemamiriro ako.

Ko Buprenorphine Zviri Nani Pane Methadone Here?

Bvose buprenorphine uye methadone mishonga inoshanda yekurapa kuwanzika kweopioid, asi anoshanda zvakasiyana uye ane zvakanakira zvakasiyana. Sarudzo pakati pavo inoenderana nezvido zvako, mararamiro, uye nhoroondo yako yekurapa.

Buprenorphine inopa zvakanakira zvakawanda pamusoro pe methadone. Iine njodzi shoma yekupfuudzwa nekuda kweceiling effect yayo, inogona kunyorerwa nemachiremba akatenderwa mumahofisi, uye kazhinji inokonzera kushoma kwekuneta uye matambudziko ekufema. Iwe zvakare une kuchinjika kwakawanda mukuyera uye haufanirwe kushanyira kiriniki zuva rega rega.

Methadone, zvisinei, inogona kunge iri nyore kune vanhu vane zvakanyanya, kudyisa kwenguva refu kweopioid kana avo vasina kupindura zvakanaka ku buprenorphine. Zvakare kazhinji hazvina kudhura uye zvakashandiswa zvakabudirira kwemakumi emakore mukurapa kwekuwedzera.

Mupi wako wehutano achafunga nezvezvinhu zvakaita senhoroondo yako yekudyisa, mamwe mishonga yaunotora, mamiriro ako ekugara, uye zvaunofarira pachako paunenge uchikurudzira sarudzo yakanakisa kwauri. Mishonga yese miviri inogona kushanda zvakanyanya kana ichishandiswa sechikamu chechirongwa chekurapa chakazara.

Mibvunzo Inowanzo Bvunzwa Nezve Buprenorphine

Buprenorphine Yakachengeteka Kune Vanhu Vane Chirwere chechiropa here?

Buprenorphine inogona kushandiswa nekuchenjerera kune vanhu vane matambudziko echiropa akapfava kusvika pakati nepakati, asi inoda kunyatso tarisa uye kazhinji kugadzirisa muyero. Chiremba wako achaongorora basa rechiropa chako nguva dzose uye anogona kukutanga pamuyero wakaderera pane wenguva dzose.

Vanhu vane chirwere chechiropa chakanyanya kana kutadza kwechiropa havafanirwe kutora buprenorphine, sezvo miviri yavo isingakwanise kugadzirisa mushonga zvakachengeteka. Kana uine matambudziko echiropa, zvakakosha kuti ukurukure izvi nemupi wako wehutano usati watanga kurapwa.

Ndoita Sei Kana Ndikashandisa Buprenorphine yakawandisa netsaona?

Kana iwe uchifunga kuti wakatora buprenorphine yakawandisa, tsvaga rubatsiro rwekurapa rwechimbichimbi nekukasira nekufonera 911 kana kuenda kukamuri rekukurumidzira riri pedyo. Kudzivirira kunogona kukonzera matambudziko ekufema akakomba, kuneta zvakanyanya, uye kurasikirwa nekuziva.

Zviratidzo zvekuwandisa buprenorphine zvinosanganisira kufema zvishoma kana kuoma, miromo yebhuruu kana zvipikiri, kuneta zvakanyanya, ganda rinotonhora uye rinonamira, uye kurasikirwa nekuziva. Usamirira kuti uone kana zviratidzo zvichivandudzika, sezvo kurapwa kwekurapa nekukurumidza kwakakosha kuchengeteka.

Ndoita Sei Kana Ndikakanganwa Dose yeBuprenorphine?

Kana ukakanganwa dose ye buprenorphine, itore paunorangarira, kunze kwekunge yava nguva yekuenda kune yako inotevera dose yakarongwa. Muchiitiko ichocho, svika dose yakakanganwa uye uenderere mberi nechirongwa chako chekushandisa.

Usambofa wakatora madosi maviri panguva imwe chete kuti ugadzirise dose yakakanganwa, sezvo izvi zvinogona kuwedzera njodzi yako yemigumisiro. Kana usina chokwadi chekuti chii chekuita kana wakakanganwa madosi akawanda, taura nemupi wako wehutano kuti uwane gwara.

Ndingamira Rini Kutora Buprenorphine?

Sarudzo yekumira kutora buprenorphine inofanira kugara ichiitwa negwara uye rutsigiro rwechiremba wako. Kumira kamwe kamwe kunogona kukonzera zviratidzo zvekubvisa zvisingafadzi, saka chiremba wako anowanzo kurumbidza kuderedzwa zvishoma nezvishoma mune dose kwemavhiki akati wandei kana mwedzi.

Nguva inoenderana nezvinangwa zvako zvekurapa, kwenguva yakadii yave uchitora mushonga, uye kufambira mberi kwako kwese. Vamwe vanhu vanobatsirwa nekurapa kwenguva refu, nepo vamwe vachigona kuve vakagadzirira kudzikisa mushure mekuwana kugadzikana mukupora kwavo kana manejimendi ekurwadziwa.

Ndingatyaira Here Ndichitora Buprenorphine?

Buprenorphine inogona kukonzera kuneta, dzungu, uye nguva dzekuita dzakaderedzwa, kunyanya paunotanga kutora kana dose yako ichigadziriswa. Hauzofaniri kutyaira kana kushandisa michina kusvikira waziva kuti mushonga unokukanganisa sei iwe pachako.

Paunenge wagadzikana pane yako dose uye usingachina migumisiro yakaita sekuneta kana dzungu, vanhu vazhinji vanogona kutyaira zvakachengeteka. Zvisinei, zvakakosha kuva akatendeseka newe pachako pamusoro pekunyatsoteerera kwako uye nguva dzekuita, uye nguva dzose tevera zvinokurudzirwa zvakananga zvechiremba wako pamusoro pekutyaira.