Chii chinonzi Buprenorphine-Naloxone: Zvinoshandiswa, Dosage, Side Effects uye Zvimwe

Buprenorphine-naloxone mushonga unopiwa nachiremba unosanganisa mishonga miviri ine simba kubatsira vanhu kupora kubva mukupindwa muropa neopioid. Musanganiswa uyu unoshanda nekuderedza zviratidzo zvekubvisa uye zvishuvo ukuwo uchivharira mhedzisiro yeimwe opioids, zvichiita kuti ive kurapa kwakakosha kweopioid kushandiswa disorder.

Unotora mushonga uyu nekuisa firimu kana piritsi pasi perurimi rwako kana mukati mematama ako, uko kunonyungudika zvishoma nezvishoma. Iyi nzira yekutumira yakakosha inobatsira muviri wako kutora mushonga zvakanaka uku uchikuchengetedza kubva mukushandisa zvisizvo.

Chii chinonzi Buprenorphine-Naloxone?

Buprenorphine-naloxone imushonga unosanganiswa unorapa kupindwa muropa neopioid nekushanda pane imwecheteyo yehuropi receptors iyo opioids inokanganisa. Chinhu chekutanga, buprenorphine, i partial opioid agonist inobatsira kuderedza zviratidzo zvekubvisa uye zvishuvo pasina kukonzera yakazara opioid high.

Chinhu chechipiri, naloxone, chinoshanda sechinhu chekuchengetedza. Paunotora mushonga sezvakanyorwa pasi perurimi rwako, naloxone inoramba isina basa. Zvisinei, kana mumwe munhu akaedza kuisa kana kushandisa zvisizvo mushonga, naloxone inodzivisa opioid mhedzisiro uye inogona kukonzera zviratidzo zvekubvisa.

Musanganiswa uyu wakangwara unoita kuti mushonga uve unobatsira pakurapa uye wakachengeteka kubva mukushungurudzwa. Chiremba wako angangodaidza nemazita emhando seSuboxone, Zubsolv, kana Bunavail, asi vese vane izvi zvakafanana zviviri zvinoshanda.

Chii chinonzi Buprenorphine-Naloxone Chinoshandiswa Kuti?

Mushonga uyu unonyanya kurapa opioid kushandiswa disorder, kubatsira vanhu vanovimba nemishonga yekurwadziwa, heroin, kana mamwe maopioid. Iyo chikamu che nzira yekurapa yakazara inonzi medication-assisted treatment (MAT) iyo inosanganisira counseling uye tsigiro yetsika.

Chiremba wako angangokupa mushonga uyu munguva mbiri huru dzekupora. Chekutanga, inobatsira kudzora zviratidzo zvekubvisa kana uchirega mamwe maopioids. Mushonga unoderedza zviratidzo zvisingafadzi zvemuviri zvakaita semarwadzo, kurwadziwa kwemhasuru, nekushushikana izvo zvinoita kuti kusiya kuve kwakaoma.

Chechipiri, inopa kurapwa kwenguva refu kudzivirira kudzoka. Nekugutsa maopioid receptors ehuropi hwako nemushonga unodzorwa, wakachengeteka, inoderedza chido uye inokubatsira kuti utarise pakuvakazve hupenyu hwako pasina kukurumidza kushandisa mamwe maopioids.

Buprenorphine-Naloxone Inoshanda Sei?

Mushonga uyu unoshanda nekunamatira kune imwecheteyo maopioid receptors muuropi hwako ayo mamwe maopioids anotariswa, asi inozvibata zvakasiyana. Buprenorphine ndizvo zvinodaidzwa nachiremba kuti partial opioid agonist, zvinoreva kuti inongoshandisa chikamu cheizvi receptors panzvimbo yekuzvikurudzira zvizere sezvinoita mamwe maopioids.

Funga nezvazvo sekunge uine mhedzisiro yedenga - hazvina mhosva kuti unotora zvakadii, buprenorphine inogona chete kugadzira mhinduro shoma. Izvi zvinoita kuti zvive zvakachengeteka zvakanyanya kupfuura maopioids akazara nekuti hazviite kuti zvikonzerese mhedzisiro ine njodzi yakaita sekufema kwakaderera, kunyanya pamadosi akakwira.

Chikamu chenaloxone chinoshanda sechinhu chakavakirwa mukati mekuchengetedza. Paunotora mushonga nemazvo pasi perurimi rwako, naloxone shoma inotorwa mumuviri wako. Zvisinei, kana mumwe munhu akaedza kuisa mushonga kuti awane high, naloxone inova inoshanda uye inovharisa mhedzisiro yeopioid.

Iyi musanganiswa inoonekwa semushonga une simba zvine mwero mukurapa kwekuwedzera. Iine simba rakakwana kudzivirira kubvisa uye kuderedza chido, asi yakachengeteka kupfuura maopioid agonists akazara se methadone.

Ndinofanira Kutora Sei Buprenorphine-Naloxone?

Unofanira kutora mushonga uyu sezvaunorairwa nachiremba wako, kazhinji kamwe chete pazuva mangwanani. Chinhu chakanyanya kukosha ndechokuisa firimu kana piritsi pasi perurimi rwako kana mukati mematama ako uye rega rinyunguduke zvakakwana - izvi zvinowanzo tora maminitsi mashanu kusvika gumi.

Usatsenga, kumedza, kana kufambisa mushonga mumuromo mako uchinyunguduka. Dzivisa kudya, kunwa, kana kusvuta panguva ino, sezvo zviitiko izvi zvinogona kukanganisa kuti muviri wako unotora sei mushonga.

Unogona kutora mushonga uyu uine kana usina chikafu, asi vanhu vazhinji vanozviwana zviri nyore kutora mangwanani vasati vadya. Kana ukaona kusvotwa, kuutora nechikafu chidiki chingabatsira, asi mirira kusvikira mushonga wanyunguduka zvakakwana.

Chiremba wako achakutanga padosi yakaderera uye zvishoma nezvishoma achiigadzirisa zvichienderana nekuti unopindura sei. Usambochinja dosi yako usina kutaura nemupi wehutano wako kutanga, sezvo kuwana huwandu hwakakodzera kwakakosha kuchengeteka kwako uye kubudirira mukurapa.

Ndingatora Buprenorphine-Naloxone Kwenguva Yakareba Sei?

Kureba kwekurapa kunosiyana zvakanyanya kubva kumunhu nemunhu, uye hapana nguva yakajairika inoshanda kune vese. Vamwe vanhu vanobatsirwa nekurapa kwenguva pfupi kunotora mwedzi yakati wandei, nepo vamwe vachida kurapa kwenguva refu kunogona kuenderera mberi kwemakore.

Chiremba wako achashanda newe kuti aone nguva yakanakisa zvichienderana nemamiriro ako. Zvinhu zvakaita sekuti wakashandisa maopioid kwenguva yakareba sei, hutano hwako hwese, tsigiro yemagariro, uye zvinangwa zvako zvekupora zvinokanganisa sarudzo iyi.

Vanhu vazhinji vanoona kuti nguva refu yekurapa inopa mhedzisiro iri nani uye inoderedza njodzi yekudzoka. Tsvagiridzo inoratidza kuti kugara pamushonga-kubatsirwa nekurapa kwegore rimwe chete kazhinji kunotungamira kubudirira kwenguva refu, asi vamwe vanhu vanobatsirwa nekurapa kwenguva refu.

Chinhu chikuru kushanda pamwe chete nechikwata chako chekuchengetwa kwehutano kuti uwane zvakakunakira. Chirongwa chako chekurapa chinofanira kunzwa chichitsigira uye chichigoneka, kwete kukurumidza kana kumanikidzwa.

Ndezvipi Zvakaipa zveBuprenorphine-Naloxone?

Semishonga yese, buprenorphine-naloxone inogona kukonzera mhedzisiro, kunyangwe kwete munhu wese achizviona. Mazhinji emhedzisiro yacho akapfava kusvika pakati nepakati uye anowanzoita nani muviri wako uchigadzirisa mushonga mumavhiki mashoma ekutanga.

Heano mhedzisiro yakajairika yaungasangana nayo muviri wako uchijaira mushonga:

• Kutemwa nemusoro uye dzungu
• Nausea uye dumbu rinogumbuka
• Kuzvimbirwa
• Kuzara kana kuneta
• Kutukwa zvakanyanya kupfuura zvakajairika
• Matambudziko ekurara kana zviroto zvakajeka
• Kufa nhengo yemuromo kana kutsamwa kwaunoisa mushonga

Izvi zvinowanzoitika zvinowanzoita zvishoma sezvo muviri wako uchigadzirisa. Kunwa mvura yakawanda, kudya chikafu chine fiber yakawanda, uye kuchengetedza hutano hwakanaka hwemuromo zvinogona kubatsira kubata zvimwe zvezviitiko izvi.

Zvimwe zvinokuvadza zvinogona kuitika, kunyangwe zvisingawanzoitiki. Unofanira kubata chiremba wako nekukasira kana ukaona chero zviratidzo zvinonetsa izvi:

• Kuzara kwakanyanya kana kuoma kuramba wakamuka
• Kufema kunonoka, kusingadzike, kana kuoma
• Kurwadziwa mudumbu kwakanyanya kana kurutsa kusingaperi
• Zviratidzo zvekuita allergic senge rash, kuita ganda kana kuzvimba
• Kuvhiringidzika kana shanduko dzemafungiro
• Kuzvimbirwa kwakanyanya kunogara mazuva anopfuura mashoma

Kazhinji, vamwe vanhu vanogona kusangana nematambudziko echiropa kana nyaya dzegland ye adrenal. Chiremba wako achatarisa hutano hwako nekutarisa nguva dzose uye bvunzo dzeropa kuti abate chero matambudziko kare.

Ndiani Asingafaniri Kutora Buprenorphine-Naloxone?

Vanhu vakati wandei vanofanira kudzivisa mushonga uyu kana kuushandisa nekuchenjerera kukuru. Chiremba wako achanyatsoongorora nhoroondo yako yezvokurapa asati akupa buprenorphine-naloxone kuti ave nechokwadi chekuti zvakachengeteka kwauri.

Haufaniri kutora mushonga uyu kana uchiziva kuti une allergy ku buprenorphine kana naloxone. Vanhu vane matambudziko ekufema akakomba, senge kuora mwoyo kukuru kwekufema, vanofanirawo kudzivisa mushonga uyu sezvo unogona kuwedzera mamiriro aya.

Mamiriro ezvinhu akati wandei ezvokurapa anoda kufunga kwakakosha usati watanga kurapwa. Chiremba wako achada kukutarisa zvakanyanya kana uine chero mamiriro aya:

• Chirwere chechiropa kana hepatitis
• Matambudziko eitsvo
• Matambudziko emoyo
• Kuderera kweropa
• Kukuvara kwemusoro kana matambudziko ehuropi
• Chirwere che gallbladder
• Matambudziko e adrenal gland
• Prostate yakakura kana matambudziko ekuyera

Kuzvitakura nekuyamwisa zvinoda kufunga kwakakosha. Kunyange buprenorphine-naloxone ichigona kushandiswa panguva yekuzvitakura kana mabhenefiti achipfuura njodzi, chiremba wako angakuchinjira ku buprenorphine chete kuti udzivise kuratidza mwana wako ku naloxone.

Zera zvakare rine basa - vanhu vakuru vangave vanonyanya kukanganiswa nemigumisiro yemushonga uye vanoda madosi akaderera kana kuongororwa kakawanda.

Mazita eBuprenorphine-Naloxone Brand

Mushonga uyu unowanikwa pasi pemazita akati wandei emhando, imwe neimwe iine mafomula akasiyana zvishoma asi iine zvinhu zvakafanana zvinoshanda. Mhando inonyanya kupihwa ndeye Suboxone, iyo inouya semufirimu unonyungudika pasi perurimi rwako.

Mamwe mazita emhando anosanganisira Zubsolv, iyo inouya semapiritsi anonyungudika pasi perurimi rwako, uye Bunavail, iyo ifirimu raunoisa mukati mematama ako. Chiremba wako angangokupawo mhando dzakajairika, dzine zvinhu zvakafanana zvinoshanda asi zvinodhura zvishoma.

Mhando dzakasiyana dzinenge dzichishanda zvakafanana, asi dzinogona kunge dziine simba rakasiyana rinowanika kana mwero wekunyudzwa wakasiyana zvishoma. Chiremba wako achasarudza sarudzo yakanakisa zvichienderana nezvido zvako zvakananga uye inishuwarenzi yako.

Zvimwe Zvinhu Zvokutsiva Buprenorphine-Naloxone

Mishonga yakati wandei inogona kurapa chirwere chekushandisa opioid, uye chiremba wako angangofunga nezvezvimwe zvinhu izvi kana buprenorphine-naloxone isiri iyo yakakunakira. Sarudzo imwe neimwe ine mabhenefiti ayo uye zvinhu zvekufunga nezvazvo.

Methadone iopioid agonist yakazara inoshanda zvakanyanya kurapa kuoma kweopioid, asi inoda kushanya zuva nezuva kuchipatara chakakosha. Zvingave zviri nani kune vanhu vasina kupindura zvakanaka ku buprenorphine-naloxone kana vane kuoma kwakanyanya, kwenguva refu opioid dependence.

Naltrexone iopioid blocker inouya semupiritsi wezuva nezuva kana jekiseni remwedzi. Kusiyana ne buprenorphine-naloxone, haibatsiri nezviratidzo zvekubvisa, saka unofanirwa kunge usina zvachose maopioid usati watanga. Inoshanda zvakanaka kune vanhu vanoda kudzivirira chero mushonga weopioid-like.

Buprenorphine yega (isina naloxone) dzimwe nguva inoshandiswa, kunyanya panguva yekuzvitakura. Inoshanda zvakafanana nemushonga wemubatanidzwa asi isina zvinhu zvekudzivirira kushandiswa zvisina kufanira zve naloxone.

Ko Buprenorphine-Naloxone Yakanyanya Here Kudarika Methadone?

Zvese buprenorphine-naloxone uye methadone ndiyo mishonga inoshanda yekurapa opioid use disorder, asi vane zvakasiyana zvakanakira zvinoita kuti imwe ive nani kune vamwe vanhu. Sarudzo yakanakisa inoenderana nemamiriro ako ega, mararamiro, uye zvinangwa zvekurapa.

Buprenorphine-naloxone inopa kuchinjika uye nyore. Unogona kuitora kumba kamwe pazuva, uye ine ceiling effect inoita kuti overdose isanyanya kuitika. Zvakare zviri nyore kumira kutora paunenge wagadzirira, uine zviratidzo zvekubvisa zvishoma.

Methadone ingaite inoshanda zvakanyanya kune vanhu vane opioid dependence yakakomba, yenguva refu kana avo vasina kupindura zvakanaka kune buprenorphine-naloxone. Zvisinei, inoda kushanya kuchipatara mazuva ose uye ine njodzi yakakwirira yekunyanyisa uye kusangana kwemishonga.

Chiremba wako achafunga nezvezvinhu zvakaita senhoroondo yako yekushandisa opioid, mararamiro, mamwe mishonga, uye zvaunoda iwe pachako paanokubatsira kusarudza pakati pezvisarudzo izvi.

Mibvunzo Inowanzo Bvunzwa Nezve Buprenorphine-Naloxone

Buprenorphine-Naloxone Yakachengeteka Here Kune Chirwere chechiropa?

Vanhu vane chirwere chechiropa vanogona kazhinji kutora buprenorphine-naloxone, asi vanoda kutarisa zvakanyanya uye vanogona kuda madosi akaderera. Chiropa chako chinogadzirisa mushonga uyu, saka matambudziko echiropa anogona kukanganisa kuti muviri wako unogadzirisa sei.

Chiremba wako achaongorora basa rechiropa chako nemiedzo yeropa usati watanga kurapwa uye nguva dzose panguva yekurapwa. Kana uine chirwere chechiropa chinyoro kusvika pakati nepakati, unogona kunge uchikwanisa kutora mushonga uyu zvakachengeteka nekugadzirisa dose.

Vanhu vane chirwere chechiropa chakakomba vanogona kuda kufunga nezveimwe nzira dzekurapa kana kutora madosi akaderera zvikuru. Nguva dzose ita chokwadi nachiremba wako nezvematambudziko echiropa, kusanganisira hepatitis kana kushandisa doro zvakanyanya.

Ndingaita Sei Kana Ndikashandisa Buprenorphine-Naloxone yakawandisa netsaona?

Kana iwe ukatora zvakawanda kupfuura zvakarairwa, taura nachiremba wako, nzvimbo yekudzora muchetura, kana masevhisi ekukurumidzira nekukasira. Kunyange buprenorphine-naloxone yakachengeteka kupfuura maopioid mazhinji nekuda kweceiling effect yayo, kutora zvakanyanya kunogona kuva nenjodzi.

Zviratidzo zvekutora zvakawanda zvinosanganisira kurara zvakanyanya, kufema kunonoka kana kuoma, kuvhiringidzika, kana kurasikirwa nekuziva. Usamirira kuti uone kana zviratidzo zvichikura - tsvaga rubatsiro rwekurapa nekukasira kana wakatora zvakawanda kupfuura zvakarairwa.

Chengetai mapakeji emishonga nemi kana muchitsvaga rubatsiro, sezvo nyanzvi dzezvekurapa dzichazoda kuziva chaizvo zvamatorwa uye zvakawanda sei. Musamboedza kuzviita kuti murutse kunze kwekunge makarayirwa zvakananga nachiremba.

Ndoita Sei Kana Ndakanganwa Dose yeBuprenorphine-Naloxone?

Kana mukakanganwa dose, itorai pakarepo pamunoyeuka, kunze kwekunge yava nguva yekuita dose yenyu inotevera. Musaite madosi maviri panguva imwe chete kuti muzadze dose yakakanganwa, sezvo izvi zvinogona kuwedzera njodzi yezvinhu zvisingadiwi.

Kana mukakanganwa madosi akawanda, taurai nachiremba wenyu musati matora dose yenyu inotevera. Zvichienderana nekuti zvatora nguva yakareba sei, mungada kutarisirwa nachiremba kuti mutangezve mushonga zvakachengeteka, kunyanya kana musina kuutora kwemazuva akati wandei.

Edzai kutora mushonga wenyu panguva imwe chete zuva rega rega kuti mubatsirwe kuyeuka. Kuisa alarm kana kushandisa chirongwa chemishonga kunogona kukubatsirai kuti murambe muchitevera chirongwa chenyu chekurapa.

Ndingamira Rini Kutora Buprenorphine-Naloxone?

Sarudzo yekumira kutora buprenorphine-naloxone inofanira kugara ichiitwa nemutungamiri wechiremba wenyu. Kumira nekukurumidza kana pasina kuronga kwakanaka kunogona kukonzera zviratidzo zvekubviswa uye kuwedzera njodzi yekudzokera kumashure.

Chiremba wenyu anowanzo kuraira kuderedza zvishoma nezvishoma dose yenyu kwemavhiki akati wandei kana mwedzi panzvimbo yekumira kamwe kamwe. Iyi nzira, inonzi tapering, inobatsira muviri wenyu kuti ujairane uye inoderedza zviratidzo zvekubviswa.

Zviratidzo zvekuti mungave makagadzirira kufunga kumira zvinosanganisira kunzwa makagadzikana mukupora kwenyu, kuva netsigiro yakasimba, uye kuva nemaitiro ekugadzirisa akagwinya. Zvisinei, vanhu vakawanda vanobatsirwa nekugara vachitora mushonga kwenguva refu, uye hapana nyadzi mukuramba muchirapwa chero bedzi ichikubatsirai.

Ndingatyaira Here Ndichitora Buprenorphine-Naloxone?

Unofanira kudzivisa kutyaira kana kushandisa michina paunotanga kutora buprenorphine-naloxone, nekuti inogona kukonzera kurara uye dzungu. Kana muviri wako wajaira mushonga uye iwe uchiziva kuti unokukanganisa sei, unogona kukwanisa kutyaira zvakachengeteka.

Taura nachiremba wako nezvekuti zvakachengeteka riini kuti utangezve kutyaira. Vachafunga nezvezvinhu zvakaita sedosi yako, kuti wanga uchitora mushonga kwenguva yakareba sei, uye kana iwe uchiona mhedzisiro inogona kukanganisa kugona kwako kutyaira.

Rangarira kuti kutyaira uchishandisa chero mushonga unokanganisa kugona kwako hakusi pamutemo uye kunotyisa. Kana iwe ukanzwa kurara, dzungu, kana kukanganiswa neimwe nzira, usatyaira zvisinei nekuti wanga uchitora mushonga kwenguva yakareba sei.