Chii chinonzi Clozapine: Zvinoshandiswa, Madosi, Matambudziko, nezvimwe

Clozapine mushonga une simba weantipsychotic unotaurwa nachiremba kana mamwe marapirwo asina kushanda zvakanaka. Mushonga uyu ndeweboka rakakosha rinonzi atypical antipsychotics, uye rinoonekwa seimwe yesarudzo dzinoshanda zvakanyanya kune mamwe mamiriro ehutano hwepfungwa, kunyanya kurapwa-kunodzivisa schizophrenia.

Chinonyanya kuita clozapine chakasiyana ndechekuti chinoda kunyatsoongororwa kuburikidza nemiedzo yeropa yenguva dzose. Kunyangwe izvi zvichigona kurira zvichikonzera, izvi zvekuchenjerera zviripo nekuti clozapine inogona kubatsira zvinoshamisa vanhu vasina kuwana zororo nemamwe mishonga.

Chii chinonzi Clozapine?

Clozapine mushonga weantipsychotic unoshanda zvakasiyana nemamwe akawanda emishonga yepfungwa. Yakanga iri imwe yeiyo yekutanga atypical antipsychotics yakagadzirwa, uye inoramba iri goridhe chiyero chekurapa kune mamwe mamiriro.

Mushonga uyu unokanganisa makemikari akawanda ehuropi, kusanganisira dopamine uye serotonin, izvo zvinobatsira kutsanangura nei ichigona kushanda kana mamwe marapirwo asina kushanda. Funga nezvazvo semaitiro akazara ekuenzanisa kemisitiri yehuropi.

Nekuda kwezvinhu zvayo zvakasiyana uye matambudziko anogona kuitika, clozapine inowanzo chengeterwa mamiriro chaiwo apo mamwe mishonga asina kupa zororo rakakwana. Chiremba wako achangofunga nezvemushonga uyu mushure mekunyatso kuyera mabhenefiti achipesana nenjodzi.

Clozapine Inoshandiswa Kunei?

Clozapine inonyanya kutaurwa ye kurapwa-inodzivisa schizophrenia, zvinoreva schizophrenia isina kupindura zvakanaka kune angangoita maviri mamwe antipsychotic mishonga. Inoshandiswawo kuderedza maitiro ekuuraya vanhu vane schizophrenia kana zvirwere zvine hukama.

Chiremba wako angakurudzira clozapine kana wakaedza mishonga mimwe ye antipsychotic kwenguva yakakwana usina kuona kuvandudzwa kwakakwana muzviratidzo zvako. Izvi zvinogona kusanganisira zviratidzo zvenguva refu, zvekufungidzira, kana zvimwe zviratidzo zvinokanganisa zvikuru hupenyu hwako hwezuva nezuva.

Dzimwe nguva, vanachiremba vanonyorawo clozapine kune mamwe mamiriro akadai se bipolar disorder kana matambudziko akakomba ekuzvibata, kunyange zvazvo kushandiswa uku kusiri kwakajairika. Sarudzo yekushandisa clozapine inogara ichibatanidza kufunga zvakanyanya nezve mamiriro ako chaiwo uye nhoroondo yekurapa.

Clozapine Inoshanda Sei?

Clozapine inoshanda nekudzivisa mamwe ma receptors muuropi hwako, kunyanya dopamine uye serotonin receptors. Kusiyana nemamwe ma antipsychotics mazhinji, ine maitiro akasiyana ekuita kwe receptor inoita kuti ive inonyanya kushanda kune kesi dzinodzivirira kurapwa.

Mishonga iyi inoonekwa se antipsychotic yakasimba uye inoshanda zvakanyanya, asi inoshanda zvinyoro-nyoro munzvimbo dzeuropi dzine chekuita nekufamba. Izvi zvinoreva kuti hazviiti kuti zvikonzere mhedzisiro yemotokari iyo vamwe vanhu vanowana nemamwe ma antipsychotics.

Nzira chaiyo iyo clozapine inobatsira nayo nezviratidzo zvepfungwa haizivikanwi zvizere, asi chiito chayo chakakura pamasisitimu akawanda ehuropi anogona kubatsira mukushanda kwayo. Inonyanya kubatsira kudzorera chiyero chiri nani chemakemikari ehuropi anokanganisa mafungiro, kufunga, uye kunzwisisa.

Ndingatora Sei Clozapine?

Tora clozapine sezvinorayirwa nachiremba wako, kazhinji kamwe kana kaviri pazuva uine kana pasina chikafu. Unogona kuitora nemukaka, mvura, kana muto, uye hazvina basa kuti unodya usati kana watora.

Kana uchitora kaviri pazuva, edza kupatsanura zvikamu zvakaenzana zuva rese. Vanhu vazhinji vanoona zvichibatsira kutora clozapine panguva imwe chete zuva rega rega kuti vachengetedze mazinga akagadzikana muhurongwa hwavo.

Tangira nemushonga mudiki uyo chiremba wako achawedzera zvishoma nezvishoma kwemavhiki akati wandei. Kuwedzera uku zvishoma nezvishoma kunobatsira muviri wako kuti ujairane nemushonga uye kunoderedza njodzi yezvinhu zvisingadiwi. Usambochinja mushonga wako usina kutanga wataura nachiremba wako.

Unoda kuongororwa ropa nguva dzose paunenge uchitora clozapine, kunyanya mumwedzi mishoma yekutanga. Miedzo iyi inoongorora huwandu hwemasero ako machena eropa kuti uve nechokwadi chekuti mushonga wacho wakachengeteka kuti urambe uchiutora.

Ndingatora Clozapine Kwenguva Yakareba Sei?

Vanhu vazhinji vanotora clozapine kwemwedzi kana makore, sezvo inowanzo kurairwa kune mamiriro akareba anoda manejimendi enguva refu. Kureba chaiko kunoenderana nekupindura kwako kwega uye kuongorora chiremba wako zvezvido zvako zvinoramba zvichiitika.

Chiremba wako achagara achiongorora kana clozapine ichiramba iri kurapwa kwakanakisa kwauri. Vamwe vanhu vangada kuitora zvachose, nepo vamwe vangazopedzisira vachichinjira kune mamwe mishonga.

Usambomira kutora clozapine kamwe kamwe, sezvo izvi zvinogona kukonzera zviratidzo zvekubviswa kana kudzoka kwezviratidzo zvepfungwa. Kana iwe nachiremba wako mukasarudza kumisa clozapine, zvichaitwa zvishoma nezvishoma kwemavhiki akati wandei kana mwedzi.

Chinhu chakakosha ndechichengetedza kutaurirana pachena nechikwata chako chehutano nezvekuti unonzwa sei uye chero zvaunonetseka nazvo nezvekutora mushonga uyu.

Ndezvipi Zvinhu Zvisingadiwi zveClozapine?

Semishonga yese, clozapine inogona kukonzera zvinhu zvisingadiwi, kunyangwe kwete munhu wese anozviwana. Kunzwisisa zvekutarisira kunogona kukubatsira kuti unzwe wakagadzirira uye uzive kuti ungataurirana riini nachiremba wako.

Zvimwe zvezvinhu zvisingadiwi zvinowanzoitika izvo vanhu vazhinji vanowana zvinosanganisira:

• Kuzara kana kurara, kunyanya kana uchitanga
• Kuwedzera kugadzirwa kwemate, kunyanya usiku
• Kuwedzera uremu nekufamba kwenguva
• Dizziness kana kumira nekukurumidza
• Kuvharika
• Kurova kwemoyo nekukurumidza
• Kuona kwakajeka

Mhedzisiro iyi inowanzoita nani muviri wako sezvaunojaira mushonga, kunyangwe dzimwe dzingaramba dziripo panguva yekurapa.

Mhedzisiro yakakomba inoda kutariswa kwekurapa nekukurumidza, kunyangwe isingawanzoitiki:

• Kuderera kwakanyanya kwemasero machena eropa (agranulocytosis)
• Kuzvimba kwemhasuru yemoyo (myocarditis)
• Moyo wakakura (cardiomyopathy)
• Kutapukirwa
• Kuvharika kwakanyanya kwemudumbu kunogona kukonzera kuvharika kwematumbu
• Fivha yakanyanya ine kuoma kwemhasuru
• Kufema kana kumedza zvakaoma

Miedzo yeropa yaunowanzoitwa yakagadzirirwa kunzwisisa mhedzisiro yakakomba, iyo iri kudonha kunotyisa kwemasero machena eropa. Iyi sisitimu yekutarisa yakaita kuti clozapine ive yakachengeteka kushandisa.

Mhedzisiro isingawanzoitiki asi yakakomba inogona kusanganisira shanduko yeshuga yeropa, matambudziko echiropa, uye mumamiriro ezvinhu asingawanzoitiki, mamiriro anonzi neuroleptic malignant syndrome. Chiremba wako achatarisa izvi kuburikidza nekutarisa nguva dzose uye miedzo yeropa.

Ndiani Asingafaniri Kutora Clozapine?

Clozapine haina kukodzera munhu wese, uye chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akuisa mushonga. Mamwe mamiriro kana mamiriro anoita kuti clozapine isachengeteka kana kusakodzera.

Haufaniri kutora clozapine kana uine:

• Nhoroondo yekuderera kwakanyanya kwemasero machena eropa
• Epilepsy isingadzoreki kana zvirwere zvekurwara
• Moyo wakakomba, itsvo, kana chirwere chechiropa
• Nhoroondo yeclozapine-induced agranulocytosis
• Kuderera kwakanyanya kwetsinga dzepakati
• Paralytic ileus (kuvharika kwakanyanya kwematumbu)

Kungwarira kwakakosha kunodiwa kana uine chirwere cheshuga, matambudziko emoyo, glaucoma, prostate yakakura, kana kana uri munhu mukuru. Chiremba wako achayerera mabhenefiti achipesana nenjodzi mumamiriro ezvinhu aya.

Vakadzi vane pamuviri kana vanoyamwisa vanoda kutariswa zvakanyanya, sezvo clozapine inogona kukanganisa mwana ari kukura. Kana uri kuronga kuva nepamuviri kana wakatova nepamuviri, taura izvi nachiremba wako nekukasira.

Vanhu vane nhoroondo yekushandisa zvinodhaka zvisiri pamutemo vangangodawo kutariswa zvakanyanya, sezvo clozapine inogona kushamwaridzana nedoro nezvimwe zvinodhaka.

Mazita eClozapine Brand

Clozapine inowanikwa pasi pemazita akati wandei emhando, neClozaril ndiyo mhando yekutanga inozivikanwa zvakanyanya. Mamwe mazita emhando anosanganisira Versacloz, iyo inouya semumvuri wemuromo, uye FazaClo, iyo iri piritsi rinoparara mumuromo.

Mhando dzakajairika dzeclozapine dziripo zvakare uye dzinobata zvakanyanya semhando dzemhando. Kusarudza pakati pemhando uye generic kazhinji kunoenderana nekavharidhe yeinishuwarenzi uye zvaunofarira.

Chiremba wako kana wezvemishonga anogona kukubatsira kunzwisisa kuti ndeipi fomu ingashanda zvakanyanya kwauri. Vamwe vanhu vanosarudza fomu yemvura kana vachinetseka kumedza mahwendefa, nepo vamwe vachida mahwendefa anoparara kuti ave nyore.

Zvimwe Zvingasarudzwa zveClozapine

Mishonga yakati wandei inowanikwa kana clozapine isingakukodzere kana ukawana mhedzisiro isingashiviriki. Izvi zvinotsiva zvinowanzoedzwa pamberi peclozapine, sezvo kazhinji vaine zvidiki zvekutarisa zvinodiwa.

Zvinowanzoitika zvinosanganisira mamwe maantipsychotics asina kujairika seolanzapine, risperidone, quetiapine, kana aripiprazole. Imwe neimwe ine yayo mbiri yezvakanakira uye mhedzisiro, uye zvinoshanda zvakanyanya zvinosiyana kubva kumunhu nemunhu.

Mune zvimwe zviitiko, vanachiremba vanogona kukurudzira kurapwa kwakabatanidzwa kana kuwedzera-pamishonga kuti vawedzere kushanda kwemamwe maantipsychotics. Iyi nzira dzimwe nguva inogona kupa zvakafanana zvakanakira clozapine pasina kudiwa kwekutariswa kwakanyanya.

Sarudzo yezvimwe zvinotsiva zvinoenderana nezviratidzo zvako zvakajeka, nhoroondo yako yezvokurapa, uye maitiro ako kumishonga yapfuura. Chiremba wako achashanda newe kuti awane sarudzo yakakodzera.

Clozapine iri nani here pane Olanzapine?

Clozapine inowanzofungidzirwa kuti inoshanda zvakanyanya kupfuura olanzapine pakurapa schizophrenia isingapinduri, asi inoda kuongororwa kwakanyanya. Sarudzo pakati pavo inoenderana nemamiriro ako chaiwo uye nhoroondo yekurapa.

Olanzapine inowanzoedzwa kutanga nekuti zviri nyore kubata uye ine mashoma mativi akakomba. Zvisinei, kana olanzapine isingapi rubatsiro rwakakwana rwezviratidzo, clozapine inogona kunge iri sarudzo iri nani pasinei nezvinodiwa zvekutarisa.

Mishonga yese miviri inogona kukonzera kuwedzera uremu uye shanduko yemetabolic, asi clozapine inoda bvunzo dzeropa nguva dzose nepo olanzapine isingadi. Vamwe vanhu vanopindura zviri nani kune imwe pane imwe, ndosaka kurapwa kuchiwanzoitwa munhu mumwe nemumwe.

Chiremba wako achafunga nezvezvinhu zvakaita sekukomba kwezviratidzo zvako, kupindura kwemishonga yapfuura, uye kugona kwako kutevedzera zvinodiwa zvekutarisa pakusarudza pakati pemishonga iyi.

Mibvunzo Inowanzo Bvunzwa Pamusoro peClozapine

Clozapine Yakachengeteka Here Kune Vanhu vane Chirwere cheShuga?

Clozapine inogona kushandiswa kune vanhu vane chirwere cheshuga, asi inoda kunyatsoongororwa mazinga eshuga yeropa. Mushonga uyu unogona kukanganisa glucose metabolism uye unogona kuwedzera kutonga kwechirwere cheshuga kune vamwe vanhu.

Chiremba wako achatarisa shuga yako yeropa kakawanda kana uine chirwere cheshuga uye uchitora clozapine. Unogona kuda kugadzirisa mishonga yako yechirwere cheshuga kana dosi re insulin. Kukurukurirana nguva dzose nachiremba wako wepfungwa uye timu yekuchengeta chirwere cheshuga kwakakosha.

Kana ukawana chirwere cheshuga uchitora clozapine, izvi hazvirevi kuti unofanira kumisa mushonga. Kazhinji, chirwere cheshuga chinogona kubatwa uchiramba uchitora clozapine kana ichipa mabhenefiti akakosha epfungwa.

Ndingaita Sei Kana Ndakashandisa Clozapine Yakawandisa Netsaona?

Kana ukatora clozapine yakawandisa netsaona, fonera masevhisi ekukurumidza kana nzvimbo yekudzora muchetura nekukasira. Kudzivisa mushonga wakawandisa kunogona kuva kwakakomba uye kunoda kutarisirwa kwekurapa nekukurumidza.

Zviratidzo zvekuwandisa clozapine zvinogona kusanganisira kurara zvakanyanya, kuvhiringidzika, kurova kwemoyo nekukurumidza, kuoma kufema, kana kurasikirwa nekuziva. Usamirira kuti uone kana zviratidzo zvichivapo, tsvaga rubatsiro nekukasira.

Paunofona kuti uwane rubatsiro, ita kuti bhodhoro rako remishonga rivepo kuti ugone kuvaudza chaizvo kuti wakatora yakawanda sei uye rini. Ruzivo urwu runobatsira nyanzvi dzekurapa kupa kurapwa kwakakodzera.

Ndingaita Sei Kana Ndakakanganwa Dose yeClozapine?

Kana ukakanganwa dose yeclozapine, itore paunorangarira, kunze kwekunge yaswedera nguva yekutora dose yako inotevera. Muchiitiko ichocho, siya dose yakakanganwa uye tora dose yako inotevera panguva yakajairika.

Usambofa wakatora madosi maviri panguva imwe chete kuti ugadzirise dose yakakanganwa, sezvo izvi zvinogona kuwedzera njodzi yako yemigumisiro. Kana usina chokwadi chekuti chii chekuita, fonera chiremba wako kana wemishonga kuti uwane gwara.

Kana ukakanganwa madosi kazhinji kana kwemazuva akati wandei akateedzana, fonera chiremba wako usati watangazve. Unogona kuda kutangazve padosi yakaderera uye zvishoma nezvishoma kuwedzera zvakare kudzivirira migumisiro.

Ndingamira Rini Kutora Clozapine?

Sarudzo yekumisa clozapine inofanira kugara ichiitwa nehutungamiri hwechiremba wako, sezvo kumira kamwe kamwe kunogona kutungamira kuzviratidzo zvekubvisa kana kudzoka kwezviratidzo zvepfungwa. Vanhu vazhinji vanoda kutora clozapine kwenguva yakareba.

Chiremba wako achagaroongorora kana clozapine ichienderera mberi ichikubatsira. Zvinhu zvakaita sekugadzikana kwezviratidzo, migumisiro, uye mhando yehupenyu hwako zvese zvine basa mukusarudza uku.

Kana iwe nachiremba wako mukasarudza kumisa clozapine, zvichaitwa zvishoma nezvishoma kwemavhiki akati wandei kana mwedzi. Munguva iyi, iwe uchatariswa zvakanyanya kune chero zviratidzo zvekudzoka kana mhedzisiro yekubvisa.

Ndinganwa Doro Ndiri Kutora Clozapine Here?

Zvinowanzo kurudzirwa kudzivisa doro uchitora clozapine, nekuti doro rinogona kuwedzera mhedzisiro yekunyaradza uye zvinogona kuwedzera mhedzisiro yakaita sedzungu uye kuvhiringika.

Doro rinogonawo kukanganisa kushanda kweclozapine uye rinogona kuwedzera njodzi yako yekubatwa nepfari. Kana ukasarudza kunwa dzimwe nguva, taura izvi nachiremba wako kutanga uye usambofa wakanwa zvakanyanya.

Chenjerera zvakanyanya nezvekutyaira kana kushandisa michina kana wakanwa doro uchitora clozapine, nekuti musanganiswa unogona kukanganisa zvakanyanya kubatana kwako nekutonga.