Chii chinonzi Colistimethate: Zvinoshandiswa, Mishonga, Mhedzisiro uye Zvimwe

Colistimethate mushonga une simba unovandudzwa nachiremba kana dzimwe nzira dzisina kushanda pakurwisa zvirwere zvakakomba zvebhakitiriya. Iyo ndeyeboka remishonga inonzi polymyxins, iyo inoonekwa se "yekupedzisira nzira" yemishonga inorwisa mabhakitiriya ezvirwere zvinotyisa zvehupenyu zvinokonzerwa nemabhakitiriya anoramba mishonga yakawanda.

Mishonga iyi inopiwa sejekiseni, kungave mutsinga kana tsandanyama, nekuti inoda kushanda nekukurumidza uye nemazvo mumuviri wako wese. Kunyange zvazvo iri mushonga une simba unogona kuponesa hupenyu, inouyawo neimwe njodzi iyo timu yako yehutano ichanyatso tarisa.

Chii chinonzi Colistimethate chinoshandiswa?

Colistimethate inorapa zvirwere zvakakomba zvinokonzerwa nemabhakitiriya egram-negative asingapinduri kune mamwe maantibiotics. Chiremba wako anowanzo kuraira mushonga uyu kana uine chirwere chakakomba uye dzimwe nzira dzisina kushanda.

Zvirwere zvakajairika zvinorapwa necolistimethate zvinosanganisira pneumonia, zvirwere zveropa, zvirwere zveti, uye zvirwere zvepaganda. Inonyanya kubatsira kurwisa mabhakitiriya akadai sePseudomonas aeruginosa, Acinetobacter, uye mamwe marudzi eE. coli akave asingapinduri kune akawanda maantibiotics.

Dzimwe nguva vanachiremba vanoshandisawo colistimethate kudzivirira zvirwere muvanhu vari panjodzi huru, vakaita seavo vane cystic fibrosis kana varwere vari muintensive care units. Zvisinei, kushandiswa uku kwekudzivirira hakuna kujairika uye kunoda kufunga zvakanyanya nezve mabhenefiti achienzaniswa nenjodzi.

Colistimethate inoshanda sei?

Colistimethate inoshanda nekurwisa rusvingo rwekunze rwemaseru ebhakitiriya, zvichiita kuti aparadzane uye afe. Funga nezvazvo sekubaya maburi mubhaluni - kana rusvingo rweseru yebhakitiriya rwakuvadzwa, bhakitiriya harigoni kurarama.

Iri mushonga une simba unorwisa mabhakitiriya akawana kuramba kune mamwe mishonga. Ndizvo zvinonzi nachiremba "bactericidal" antibiotic, zvinoreva kuti inouraya mabhakitiriya panzvimbo yekungomisa kukura kwawo.

Mishonga iyi inoshandurwa kuita chimiro chayo chinoshanda chinonzi colistin kana yapinda mumuviri wako. Iyi nzira yekushandura inobatsira kuderedza mamwe emigumisiro isingadiwi asi ichichengetedza simba remishonga yekurwisa mabhakitiriya.

Ndingatora Sei Colistimethate?

Uchagamuchira colistimethate sejojo muchipatara kana munzvimbo yekiriniki, kwete semupfuhwira waunotora kumba. Mishonga iyi inopiwa kuburikidza nemutsara weIV muvheni yako kana sejojo mumhasuru yako, zvichienderana nemamiriro ako chaiwo.

Vashandi vehutano vachaverenga chiyero chako chaicho zvichienderana nehuremu hwako, basa reitsvo, uye kuoma kwehutachiona hwako. Kurapa kunowanzoitika kunosanganisira kugamuchira mishonga 2-4 nguva pazuva, nechiyero chimwe nechimwe chinopiwa zvishoma nezvishoma kwemaminitsi makumi matatu kusvika kumaawa maviri kana iri kuburikidza neIV.

Haufaniri kunetseka nezvekutora mushonga uyu nechikafu sezvo uchipiwa sejojo. Zvisinei, zvakakosha kuti ugare uine mvura yakawanda panguva yekurapa, saka inwa mvura yakawanda kunze kwekunge chiremba wako akuudza zvimwe.

Vashandi vako vezvokurapa vachakutarisa zvakanyanya panguva yekurapa, vachiongorora ropa rako nguva dzose kuti vaone kuti mushonga uri kushanda nemazvo uye haukonzere migumisiro inokuvadza.

Ndingatora Kwenguva Yakareba Sei Colistimethate?

Kureba kwekurapa necolistimethate kunowanzoita mazuva 7 kusvika ku14, asi izvi zvinogona kusiyana zvakanyanya zvichienderana nehutachiona hwako chaihwo uye maitiro ako ekurapa. Chiremba wako achasarudza nguva chaiyo zvichienderana nezvinhu zvakawanda.

Kune zvirwere zvakawanda zvebhakitiriya, unofanirwa kuramba uchirapwa kusvika bvunzo dzemurabhoritari dzichiratidza kuti mabhakitiriya apera uye zviratidzo zvako zvavandudzwa. Zvimwe zvirwere zvakakomba zvinogona kuda nguva refu yekurapa, nepo zvimwe zvichigona kupindura nekukurumidza.

Chikwata chako chehutano chichatarisa kufambira mberi kwako kuburikidza nebvunzo dzeropa dzenguva dzose, zvidzidzo zvekuongorora, uye kuongororwa kwemuviri. Vachatarisawo zviratidzo zvekuti hutachiona huri kupora, senge kuderedzwa kwemwaranzi, kufema kuri nani, kana kupora kwemavanga akabatwa.

Zvakakosha kupedzisa nzira yese yekurapa kunyangwe ukatanga kunzwa zviri nani. Kumira nekukurumidza kunogona kubvumira mabhakitiriya kudzoka akasimba uye achidzivisa kurapwa.

Ndezvipi Zvipingamupinyi zveColistimethate?

Kufanana nemishonga yese ine simba, colistimethate inogona kukonzera mhedzisiro, kunyangwe kwete munhu wese anoiziva. Mhedzisiro yakajairika inowanzo manejwa uye chikwata chako chekurapa chichazvitarisa zvakanyanya.

Heano mhedzisiro yaungasangana nayo, kutanga neayo akajairika:

• Matambudziko eitsvo, kusanganisira shanduko mukuyerera kwemvura kana kuzvimba mumakumbo ako kana tsoka
• Dizziness kana kunzwa usina kugadzikana, kunyanya kana uchimira
• Kutinhira kana kusanzwa mumawoko ako, tsoka, kana pamuromo wako
• Nausea kana dumbu rakatsamwa
• Kurwadziwa kana kutsamwa panzvimbo yekujekesa
• Musoro kana kunzwa wakavhiringidzika
• Kushaya simba kwemhasuru kana kuoma kwekubatana

Mazhinji emhedzisiro iyi idiki uye yenguva pfupi, asi chikwata chako chehutano chichakutarisa zvakanyanya kuti ubate chero matambudziko nekukurumidza. Vachatarisa basa reitsvo dzako uye mhinduro dzetsinga nguva yekurapa.

Zvimwe zvisingawanzoitiki asi zvakakomba mhedzisiro zvinosanganisira kukuvadzwa kwakanyanya kweitsvo, matambudziko ekufema, kana shanduko dzakakosha mumamiriro ako epfungwa. Chikwata chako chekurapa chakadzidziswa kuziva zviratidzo izvi uye chichatora matanho nekukurumidza kana akaitika.

Ndiani Asingafaniri Kutora Colistimethate?

Colistimethate haikodzeri munhu wese, uye chiremba wako achanyatsoongorora nhoroondo yako yezvokurapa asati akuraira. Vanhu vane mamiriro ezvinhu akati wandei vanogona kuda kurapwa kwakasiyana kana kuongororwa kwakakosha.

Haufanire kugamuchira colistimethate kana uine allergic ku colistin, polymyxin antibiotics, kana chero zvinhu zviri mumushonga. Udza timu yako yehutano nezve chero maitiro ekare ekuita allergic kune maantibiotics, kunyangwe akaita seasina hukama.

Vanhu vane matambudziko eitsvo vanoda kufunga kwakakosha, sezvo colistimethate inogona kukanganisa basa reitsvo. Chiremba wako achayera mabhenefiti achipesana nenjodzi uye anogona kugadzirisa muyero wako kana kusarudza kurapwa kwakasiyana kana itsvo dzako dzisingashande zvakanaka.

Kana uine myasthenia gravis (mamiriro ekushaya simba kwemhasuru), matambudziko etsinga, kana matambudziko ekunzwa, chiremba wako achafanirwa kukutarisa zvakanyanya. Mamiriro aya anogona kuwedzerwa ne colistimethate, kunyangwe kurapwa kungave kuchiri kudikanwa kana uine hutachiona hwakakomba.

Vakadzi vane pamuviri uye vanoyamwisa vanoda kufunga kwakakosha, sezvo paine ruzivo rushoma nezve kuchengeteka kwe colistimethate panguva yekuzvitakura. Chiremba wako achangokuraira kana mabhenefiti achipfuura njodzi dzinogona kuitika.

Mazita eColistimethate Brand

Colistimethate inowanikwa pasi pemazita akati wandei emhando, neColy-Mycin M iri imwe yeanowanzoitika muUnited States. Mamwe mazita emhando anosanganisira Colistin uye Promixin, kunyangwe kuwanikwa kuchisiyana nenyika.

Zita re generic

Kana colistimethate isingakodzeri kana kuwanikwa, chiremba wako angatarisa mamwe maantibiotics, kunyangwe sarudzo dzemabhakitiriya anoramba dzichingova shoma. Sarudzo inoenderana nekuti mabhakitiriya api ari kukonzera hutachiona hwako uye kunzwisisika kwavo kumishonga yakasiyana.

Dzimwe nzira dzinosanganisira tigecycline, iyo inoshanda pamabhakitiriya mazhinji anoramba, kana kurapa kwakabatanidzwa uchishandisa maantibiotics akawanda pamwechete. Mishonga mitsva yakaita se ceftazidime-avibactam kana meropenem-vaborbactam inogona zvakare kuva sarudzo dzemamwe marudzi ekuvhenekera.

Mune dzimwe nguva, chiremba wako angangayedza polymyxin B, iyo yakabatana zvakanyanya ne colistimethate uye inoshanda zvakafanana. Zvisinei, maprofiles emigumisiro yakafanana, saka izvi hazvisi nguva dzose imwe nzira yakanaka kana uine matambudziko ne colistimethate.

Chokwadi ndechekuti kune hutachiona hwakawanda hunoramba zvakanyanya, colistimethate inoramba iri imwe yemishonga inoshanda zvikuru iripo. Chikwata chako chekurapa chichagara chichiedza kuwana sarudzo yakachengeteka inoshanda yemamiriro ako chaiwo.

Ko Colistimethate Zviri Nani Kupfuura Mamwe Maantibiotics?

Colistimethate haisi zvakanyanya "zviri nani" kupfuura mamwe maantibiotics - inongoshanda pamabhakitiriya asingapinduri kune mamwe marapirwo. Funga nezvayo sechishandiso chakakosha chemamiriro chaiwo panzvimbo yemushonga wakanyanya.

Kune hutachiona hunokonzerwa nemabhakitiriya anonzwa kune mamwe maantibiotics, vanachiremba vanowanzo sarudza izvo zvimwe zvingasarudzwa kutanga. Izvi zvinodaro nekuti colistimethate inotakura njodzi dzakawanda dzemigumisiro, kunyanya kumatsvo uye nehurongwa hwetsinga.

Simba re colistimethate rinovanda mukukwanisa kwayo kurwisa mabhakitiriya anoramba mishonga yakawanda kana mamwe maantibiotics akatadza. Mumamiriro ezvinhu aya anotyisa upenyu, anogona kununura hupenyu, zvichiita kuti isakoshe kunyangwe paine njodzi dzayo.

Chiremba wako achagara achiedza kushandisa mushonga unonyaradza asi unoshanda pakutanga, achienda kune dzimwe nzira dzakasimba dzakadai se colistimethate chete kana zvichidikanwa. Nzira iyi inobatsira kuchengetedza kushanda kwemishonga iyi ine simba kana ichidikanwa zvechokwadi.

Mibvunzo Inowanzo Bvunzwa Pamusoro peColistimethate

Colistimethate Yakachengeteka Kune Vanhu vane Chirwere cheItsvo Here?

Colistimethate inogona kukanganisa kushanda kweitsvo, saka vanhu vane matambudziko eitsvo vanoda kutarisirwa kwakakosha uye kuongororwa. Chiremba wako achachinja muyero wako zvichienderana nekuti itsvo dzako dziri kushanda sei uye vachaongorora kushanda kweitsvo dzako nguva dzose panguva yekurapa.

Kana uine matambudziko eitsvo ari nyore, unogona kuramba uchikwanisa kugamuchira colistimethate nemuyero wakaderedzwa uye kuongororwa kwakawanda. Zvisinei, kana kushanda kweitsvo dzako kwakakanganiswa zvakanyanya, chiremba wako angangoda kufunga nezve dzimwe nzira dzekurapa kana kushandisa colistimethate chete kana zvichidikanwa zvachose.

Ndoitei Kana Ndikawana Zvakaipa Zvikuru?

Sezvo iwe uchagamuchira colistimethate muchipatara kana munzvimbo yekiriniki, timu yako yezvokurapa ichakutarisa zvakanyanya kuti uone zvakaipa. Kana ukaona chero zviratidzo zvinonetesa zvakadai sekufema kwakaoma, dzungu rakanyanya, kana shanduko huru mukuyerera kweweti, udza mukoti wako kana chiremba wako nekukasira.

Usanetseke nekunetsa vashandi vezvokurapa - vanoda kuziva nezvezvipi zvako zviratidzo zvauri kusangana nazvo. Kuona nekukurumidza uye kurapwa kwezvakaipa zvinogona kudzivirira matambudziko akakomba kuti asaitike.

Chii Chinoitika Kana Ndikakanganwa Dose yeColistimethate?

Sezvo colistimethate ichipiwa nenyanzvi dzezvehutano munzvimbo yekurapa, haufaniri kunetseka nezvekukanganwa madosi. Timu yako yezvokurapa ichave nechokwadi chekuti unogamuchira mushonga wako panguva yakatarwa sechikamu chechirongwa chako chekurapa.

Kana nokuda kwechimwe chikonzero mushonga ukasara nekuda kwemaitiro ekurapa kana mamwe marapirwo, chikwata chako chehutano chichachinja nguva zvakakodzera. Vachaita shuwa kuti unogamuchira marapirwo akazara anodiwa pachirwere chako.

Ndingamira Rini Kutora Colistimethate?

Haufanire kumira kurapwa kwecolistimethate wega - sarudzo iyi inofanira kugara ichiitwa nechikwata chako chehutano zvichibva pamhinduro yako kumishonga uye mhedzisiro yekuedzwa. Kumira nekukurumidza kunogona kubvumira chirwere kuti chidzoke chakasimba kupfuura kare.

Chiremba wako achasarudza kuti ungamira rini kurapwa zvichibva pazvinhu zvakati wandei: zviratidzo zvako zvichivandudza, bvunzo dzeropa dzichiratidza kuti chirwere chiri kubviswa, uye kuona kuti wagamuchira mishonga yakakwana kudzivirira mabhakitiriya kuti adzoke.

Colistimethate Inogona Kudyidzana Nemimwe Mishonga Here?

Hongu, colistimethate inogona kudyidzana nemimwe mishonga, ndosaka chikwata chako chekurapa chichatarisa mishonga yako yese iripo usati watanga kurapwa. Kudyidzana kwakakosha ndekune mamwe madhiragi anogona kukanganisa itsvo kana tsinga dzemuviri.

Mishonga yakaita seaminoglycoside antibiotics, mamwe ma diuretics, uye mamwe marapirwo ekurwadziwa anogona kuwedzera njodzi yematambudziko eitsvo kana akasanganiswa necolistimethate. Chikwata chako chehutano chichatarisisa kudyidzana uku uye chinogona kuchinja zviyero kana nguva yemimwe mishonga sezvinodiwa.