Chii chinonzi Conjugated Estrogens uye Bazedoxifene: Zvinoshandiswa, Dosage, Side Effects uye Zvimwe

Conjugated estrogens uye bazedoxifene imishonga yekubatanidza mahomoni inobatsira kurapa zviratidzo zvemenopause apo ichidzivirira mapfupa ako. Iyi musanganiswa wega wega unosanganisa mahomoni eestrogen ne selective estrogen receptor modulator (SERM) kuti ikupe zororo kubva kumoto unopisa uye dikita rehusiku pasina kuwedzera njodzi yako yekenza yeendometrial.

Funga nezve mushonga uyu semaitiro akaringana e hormone therapy. Chikamu cheestrogen chinotarisana nezviratidzo zvisinganzwisisike zvemenopause, nepo bazedoxifene ichiita sechidziviriro chekudzivirira uterine lining yako, ichibvisa kudiwa kwemishonga yakaparadzana ye progestin.

Chii chinonzi Conjugated Estrogens uye Bazedoxifene?

Mushonga uyu unosanganisa zvinoshanda zviviri zvinoshanda pamwechete kuti zvitungamire zviratidzo zvemenopause zvakachengeteka. Conjugated estrogens musanganiswa wemahomoni eestrogen anobva kune zvakasikwa, nepo bazedoxifene iri rudzi rutsva rwehomoni modulator iyo inosarudza estrogen receptors.

Musanganiswa uyu wakagadzirirwa zvakananga vakadzi vachiri nemimba yavo uye vanoda hormone therapy. Kusiyana neyakajairwa hormone replacement therapy iyo inoda kuwedzera progestin kudzivirira uterine lining, mushonga uyu unosanganisira bazedoxifene kuti ipe dziviriro iyoyo zvakasikwa.

Unogona kuziva mushonga uyu nezita rayo rekutengesa Duavee. Inouya sepiritsi remuromo raunotora kamwe chete pazuva, zvichiita kuti ive sarudzo iri nyore yekugadzirisa zviratidzo zvemenopause apo uchichengetedza hutano hwemapfupa.

Chii chinonzi Conjugated Estrogens uye Bazedoxifene Inoshandiswa Kune?

Mushonga uyu unonyanya kurapa kupisa kwepakati kusvika kwakanyanya uye dikita rehusiku rine chekuita ne menopause. Kana iwe uri kusangana nezviratidzo izvi zvevasomotor zvinokanganisa hupenyu hwako hwezuva nezuva kana kurara, iyi yekubatanidza therapy inogona kupa zororo rakakura.

Mushonga uyu unobatsirawo kudzivirira osteoporosis muvakadzi vakapfuura menopause avo vari panjodzi yekutyoka mapfupa. Sezvo mazinga e estrogen achiderera panguva ye menopause, mapfupa ako anogona kuita akasimba uye anowanzo tyoka. Kurapa uku kunobatsira kuchengetedza kuwanda kwemapfupa uye simba.

Chiremba wako angakurudzira mushonga uyu kana uine zviratidzo zvinonetsa zve menopause uye uchida kudzivisa kutora mishonga yakasiyana yekubatsira zviratidzo uye kuchengetedza mapfupa. Zvinobatsira zvikuru kuvakadzi vanowana mhedzisiro kubva kumishonga yechinyakare yekurapa mahomoni.

Conjugated Estrogens uye Bazedoxifene Inoshanda Sei?

Mushonga uyu unoshanda kuburikidza nemaitiro ekuita kaviri anogadzirisa zviratidzo zvemenopause uku uchidzivirira matishu ako ekubereka. Chikamu che estrogen chinotsiva mamwe emahormone anomira kugadzira muviri wako panguva ye menopause, zvichibatsira kudzora sisitimu yekudzora tembiricha yemuviri wako.

Bazedoxifene inoshanda se selective estrogen receptor modulator, zvinoreva kuti inozvibata se estrogen mune dzimwe nzvimbo dzemuviri wako (semapfupa) uku ichivharira estrogen effects mune dzimwe (semudumbu). Iyi chiito chekusarudza chinobatsira kudzivirira kuwanda kwemutsara wako we uterine uyo ​​unogona kutungamirira kunjodzi yekenza.

Mubatanidzwa uyu unoonekwa seyakati simba rekurapa mahomoni. Yakasimba zvakakwana kuti ipe rubatsiro rwakakosha rwezviratidzo uye kuchengetedzwa kwemapfupa, asi yakagadzirirwa kuderedza njodzi dzakawanda dzine chekuita nekurapa mahomoni echinyakare.

Ndingatora Sei Conjugated Estrogens uye Bazedoxifene?

Tora mushonga uyu sezvaunorairwa nachiremba wako, kazhinji piritsi rimwe nemuromo kamwe pazuva. Unogona kuitora uine chikafu kana usina, asi kuitora nechikafu kunogona kubatsira kuderedza chero dumbu rinogumbura raungasangana naro pakutanga.

Edza piritsi rako panguva imwechete zuva rega rega kuti uchengetedze mazinga emahormone mumuviri mako. Vakadzi vazhinji vanoona zvichibatsira kuzvitora nekudya kwemangwanani kana kwemanheru sechikamu chetsika yavo yezuva nezuva. Kuenderana uku kunobatsira muviri wako kuti ugadzirise kumushonga zvakanyanya.

Momedza piritsi rose negirazi remvura izere. Usapwanya, kutsenga, kana kuputsa piritsi, sezvo izvi zvinogona kukanganisa nzira iyo mushonga unotorwa uye kuburitswa mumuviri wako. Kana uine dambudziko rekumedza mapiritsi, taura nachiremba wako nezveimwe nzira.

Ndingatora Conjugated Estrogens uye Bazedoxifene kwenguva yakareba sei?

Kureba kwekurapa kunosiyana zvichienderana nezviratidzo zvako uye zvinangwa zveutano. Vakadzi vazhinji vanotora mushonga uyu kwemakore akati wandei kuti vatarise zviratidzo zvemenopause, nepo vamwe vachigona kuushandisa zvakanyanya kuchengetedza mapfupa uye kuramba vachishandisa kwenguva refu.

Chiremba wako achagara achiongorora kana uchiri kuda mushonga uyu, kazhinji mwedzi mitanhatu kusvika gumi nemiviri yega yega. Kuongororwa uku kunobatsira kuona kuti mabhenefiti anoramba achikunda chero njodzi dzinogona kuitika. Vamwe vakadzi vanoona kuti vanogona kuderedza chiyero chavo kana kumisa mushonga sezvo zviratidzo zvavo zvemenopause zvichivandudzika zvakasikwa nekufamba kwenguva.

Kuchengetedzwa kwemapfupa, kushandiswa kwenguva refu kunogona kudikanwa, kunyanya kana uine zvimwe zvinhu zvine njodzi zve osteoporosis. Chiremba wako achafunga nezve bvunzo dzako dzemapfupa, nhoroondo yemhuri, uye hutano hwese paanenge achisarudza nguva yakakodzera yekurapa.

Ndezvipi Zvakaipa zveConjugated Estrogens uye Bazedoxifene?

Semishonga yese, iyi kurapa kwemusanganiswa kunogona kukonzera mhedzisiro, kunyangwe vakadzi vazhinji vachizvitsungirira zvakanaka. Kunzwisisa zvekutarisira kunogona kukubatsira kuti unzwe wakagadzirira uye uzive kana uchifanira kutaurirana nemupi wako wehutano.

Mhedzisiro yakajairika inowanzoita nyoro uye inowanzoita nani sezvo muviri wako uchigadzirisa kumushonga mumavhiki mashoma ekutanga ekurapa.

Mhedzisiro yakajairika yaungasangana nayo inosanganisira:

• Kunzwa kusvotwa kana kusagadzikana mudumbu, kunyanya kana uchitanga mushonga
• Kutapira mazamu kana kuzvimba
• Kutemwa nemusoro, izvo zvinowanzoita zvishoma uye zvenguva pfupi
• Kubuda ropa muchikadzi kana kuona ropa, kunyanya mumwedzi mishoma yekutanga
• Kukramba kwemakumbo kana spasms dzemhasuru
• Dizziness kana kunzwa musoro

Izvi zvinowanzoitika zvinowanzoita zvishoma sezvo muviri wako uchigadzirisa kuchinja kwehomoni. Kutora mushonga uyu pamwe chete nechikafu kunogona kubatsira kuderedza kusvotwa uye kusagadzikana mudumbu.

Zvisingawanzoitiki asi zvakanyanya kukomba zvinokonzeresa zvinoda kutariswa kwechiremba nekukurumidza, kunyangwe zvichiwanzowanikwa kune vakadzi vazhinji.

Bata chiremba wako nekukurumidza kana ukaona:

• Kurwadziwa kwakanyanya mudumbu kana kusvotwa kunoramba kuripo uye kurutsa
• Kubuda ropa zvisina kujairika muchikadzi kwakanyanya kana kunoramba kuchipfuura mwedzi mishoma yekutanga
• Kutemwa nemusoro kwakanyanya kusingapinduri kurapwa kwakajairika
• Kuchinja kwekuona kana kurasikirwa nekuona kamwe kamwe
• Kurwadziwa muchipfuva kana kuoma kufema
• Kurwadziwa kwakanyanya kwemakumbo kana kuzvimba izvo zvinogona kuratidza ropa
• Kusviba kweganda rako kana maziso, izvo zvinogona kuratidza matambudziko echiropa

Nepo mhedzisiro yakakomba isingawanzoitiki, kuziva zviratidzo izvi zvekuyambira kunobatsira kuona kuti unowana kutarisirwa kwekurapa nekukurumidza kana zvichidikanwa.

Ndiani Asingafaniri Kutora Conjugated Estrogens uye Bazedoxifene?

Mushonga uyu hauna kukodzera munhu wese, uye mamiriro ehutano akati wandei anoita kuti zvisachengeteke kushandisa. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akurudzira kurapwa uku kuti ave nechokwadi chekuti zvakakunakira.

Haufanire kutora mushonga uyu kana uine nhoroondo yeropa, sitiroko, kana kurwisa kwemoyo. Chikamu cheestrogen chinogona kuwedzera njodzi yako yekuvandudza zviitiko izvi zvakakomba zve cardiovascular, kunyanya kana iwe uine zvatove zvinhu zvine njodzi.

Vakadzi vane nhoroondo yekenza yemazamu, kenza yemucheto wemimba, kana mamwe mhando dzekenza dzinonzwa mahomoni vanofanira kudzivisa mushonga uyu. Chikamu che estrogen chinogona kukuchidzira kukura kwetumor dzinonzwa mahomoni, zvichiita kuti zvisachengeteke kuvakadzi vane mamiriro aya.

Zvimwe zvinopesana zvinosanganisira:

• Chirwere chechiropa chiri kushanda kana ma enzymes echiropa akakwira zvakanyanya
• Kubuda ropa muvhavha kusingatsanangurwi kusina kuongororwa nachiremba
• Kuzivikanwa kana kufungirwa pamuviri
• Chirwere chakakomba cheitsvo
• Zvirwere zvekubuda ropa zvinogara nhaka
• Kurwadziwa kwemusoro kwakanyanya kwe migraine ne aura

Kana uine chirwere cheshuga, BP yakakwira, kana mamwe mamiriro ekusingaperi, chiremba wako achayerera zvakanakira nenjodzi zvakanyatso chenjerera asati akurudzira mushonga uyu.

Conjugated Estrogens uye Bazedoxifene Zita reBrand

Mishonga iyi yakasanganiswa inowanikwa pasi pezita rebrand Duavee muUnited States. Duavee ine 0.45 mg ye conjugated estrogens uye 20 mg ye bazedoxifene mutablet imwe neimwe.

Mishonga iyi inogadzirwa nePfizer uye yakabvumidzwa neFDA muna 2013. Parizvino ndiyo chete musanganiswa we conjugated estrogens uye bazedoxifene pamusika, saka hapana mhando dzemajenari dziripo.

Pharmacy yako dzimwe nguva inogona kuita kuti utaure nezvayo nezita rayo re generic, asi paunotora mushonga wako, uchagamuchira mahwendefa eDuavee brand. Mahwendefa acho akaita oval uye epingi, zvichiita kuti azivikanwe nyore.

Conjugated Estrogens uye Bazedoxifene Zvimwe Zvinhu

Kana mushonga uyu usingakukodzere, dzimwe nzira dzinogona kubatsira kubata zviratidzo zvemenopause uye kuchengetedza hutano hwemapfupa. Chiremba wako anogona kukubatsira kuongorora dzimwe nzira idzi zvichienderana nezvido zvako uye hutano.

Mishonga yechinyakare yekurapa mahomoni inosanganisira estrogen pamwe chete nemishonga ye progestin yakaita sePrempro kana Premphase. Sarudzo idzi dzingave dzakakodzera kana usingakwanise kutora bazedoxifene asi uchiri kuda kurapwa nemahomoni.

Dzimwe nzira dzisiri dzemahomoni dzekugadzirisa zviratidzo zvemenopause zvinosanganisira:

• Selective serotonin reuptake inhibitors (SSRIs) yakaita separoxetine (Brisdelle) yekupisa kwemuviri
• Gabapentin yekuderedza kupisa kwemuviri uye kuvandudza kurara
• Clonidine yekugadzirisa zviratidzo zvevasomotor
• Kugadziridzwa kwehupenyu kusanganisira kurovedza muviri nguva dzose uye shanduko dzekudya

Kudzivirira mapfupa zvakananga, chiremba wako angakurudzira bisphosphonates yakaita sealendronate (Fosamax) kana risedronate (Actonel), kana mamwe mishonga yakaita sedenosumab (Prolia).

Ko Conjugated Estrogens uye Bazedoxifene Zviri Nani Pane Kurapa Kwemahomoni Echinyakare?

Mubatanidzwa uyu unopa zvimwe zvakanakira pamusoro pechinyakare hormone replacement therapy, kunyanya kune vakadzi vanoda kudzivisa progestin-related side effects. Kubatanidzwa kwe bazedoxifene panzvimbo ye progestin kunogona kuderedza kuzvimba, shanduko dzemood, uye kunyorova kwemazamu ayo vamwe vakadzi vanowana neyakajairika hormone therapy.

Mishonga inogona zvakare kuve nemhedzisiro yakanaka pane yako lipid profile ichienzaniswa nemamwe mahomoni echinyakare. Zvimwe zvidzidzo zvinoratidza kuti zvinogona kubatsira kuchengetedza kana kuvandudza cholesterol mazinga uchipa menopause symptom relief.

Zvisinei, chinyakare hormone therapy inogona kunge yakakodzera kune vamwe vakadzi, kunyanya avo vanoda yakakwirisa estrogen doses kana vane hutano hwakakosha. Chiremba wako anogona kubatsira kuona kuti ndeipi nzira inokodzera zvakanyanya zvaunoda uye zvinangwa zvehutano.

Mibvunzo Inowanzo Bvunzwa Nezve Conjugated Estrogens uye Bazedoxifene

Ko Conjugated Estrogens uye Bazedoxifene Zvakachengeteka Kune Vakadzi vane Osteoporosis?

Hongu, mushonga uyu wakabvumirwa zvakananga kudzivirira osteoporosis muvakadzi vakapfuura menopause uye unogona kuva sarudzo yakanaka kana uri panjodzi yekutyoka mapfupa. Chikamu che estrogen chinobatsira kuchengetedza kuwanda kwemapfupa, nepo bazedoxifene ichipa mamwe mhedzisiro yekudzivirira mapfupa.

Chiremba wako achatarisa kuwanda kwemapfupa ako kuburikidza neDEXA scans nguva dzose kuti ave nechokwadi chekuti mushonga uri kudzivirira mapfupa ako nemazvo. Vakadzi vazhinji vanoona kuvandudzwa mumamaki avo ekuwanda kwemapfupa mukati megore rekutanga rekurapa.

Ndoita Sei Kana Ndikashandisa Zvakawandisa Conjugated Estrogens uye Bazedoxifene?

Kana ukatora zvakawanda kupfuura chiyero chawakanyorerwa, taura nachiremba wako kana nzvimbo yekudzora chepfu nekukasira. Kutora zvakawanda kunogona kuwedzera njodzi yako yemhedzisiro yakakomba senge magwamba eropa, kusvotwa kwakanyanya, kana kubuda ropa zvisina kujairika.

Usaedze "kugadzirisa" overdose nekusvetuka chiyero chako chinotevera. Pane kudaro, dzokera kuchirongwa chako chekushandisa mushonga sezvakarairwa nachiremba wako. Chengeta rekodhi rekuti overdose yakaitika riini kuitira kuti upe ruzivo rwakaringana kune nyanzvi dzekurapa.

Ndoita Sei Kana Ndikakanganwa Chiyero cheConjugated Estrogens uye Bazedoxifene?

Kana ukakanganwa chiyero, tora nekukasira paunorangarira, kunze kwekunge yava nguva yechiyero chako chinotevera. Muchiitiko ichocho, svetuka chiyero chawakakanganwa uye dzokera kuchirongwa chako chekushandisa mushonga nguva dzose.

Usambofa wakatora zviyero zviviri panguva imwe chete kuti ugadzirise chiyero chawakakanganwa, sezvo izvi zvinogona kuwedzera njodzi yako yemhedzisiro. Kana iwe uchikanganwa zviyero kazhinji, funga kumisa alarm yezuva nezuva kana kushandisa chirongwa chemushonga kuti zvikubatsire kurangarira.

Ndingamira Rini Kutora Conjugated Estrogens uye Bazedoxifene?

Unofanira kungomira kutora mushonga uyu pasi pekutungamirirwa nachiremba wako. Kumira kamwe kamwe kunogona kukonzera zviratidzo zvako zvemenopause kudzoka nekukurumidza uye zvinogona kukanganisa hutano hwemapfupa ako kana uri kutora osteoporosis kudzivirira.

Chiremba wako angaderedza zvishoma nezvishoma mushonga wako usati wamira zvachose, kunyanya kana wanga uchitora mushonga kwenguva yakareba. Iyi nzira yekuderera inogona kubatsira kuderedza kudzoka kwezviratidzo uye kuita kuti shanduko ive nyore.

Ndingatora Conjugated Estrogens uye Bazedoxifene nemimwe mishonga here?

Mushonga uyu unogona kushamwaridzana nemimwe mishonga yakawanda, saka zvakakosha kuti uudze chiremba wako nezve mishonga yese, zvinowedzera, uye zvigadzirwa zvechirimwa zvauri kutora. Mimwe mishonga inogona kuwedzera kana kuderedza kushanda kwemishonga yehomoni.

Mamwe maantibayoti, mishonga yekurwisa fungal, uye mishonga yekubata matambudziko anogona kukanganisa maitiro emuviri wako emushonga uyu. Chiremba wako angangoda kugadzirisa mushonga wako kana kukutarisa zvakanyanya kana uri kutora mhando idzi dzemishonga pamwe chete.