Chii chinonzi Cosyntropin: Zvazvinoshandiswa, Mishonga, Migumisiro Yemuviri uye Zvimwe

Cosyntropin ndiyo vhezheni yekugadzirwa yehomoni inobatsira vanachiremba kuyedza kuti adrenal glands yako iri kushanda sei. Adrenal glands yako inogara pamusoro peitsvo dzako uye inogadzira mahomoni akakosha se cortisol, iyo inobatsira muviri wako kubata kushushikana uye kuchengetedza ropa. Kana vanachiremba vachida kutarisa kana magland aya ari kushanda nemazvo, vanoshandisa cosyntropin kuvakurudzira uye kuona kuti vanopindura sei.

Chii chinonzi Cosyntropin?

Cosyntropin ikopi yakagadzirwa nemunhu yehomoni yechisikigo inonzi ACTH (adrenocorticotropic hormone). Yakagadzirirwa kutevedzera zvinoitwa ne pituitary gland yako kana ichiratidza adrenal glands yako kuti ibudise cortisol. Iyi homoni yekugadzirwa ine chikamu chinoshanda zvakanyanya cheACTH yechisikigo, ichiita kuti ive yakakwana yekuyedzwa kwekurapa.

Mishonga inouya seupfu huchena hunosanganiswa nemvura yakakosha nguva pfupi vasati chiremba wako akuisa jekiseni. Iwe unowanzo gamuchira jekiseni iri muchipatara kana kiriniki uko nyanzvi dzekurapa dzinogona kutarisa mhinduro yako zvakanyanya.

Chii chinonzi Cosyntropin chinoshandiswa?

Cosyntropin inobatsira vanachiremba kuongorora matambudziko ne adrenal glands yako kuburikidza nekuyedzwa kunonzi ACTH stimulation test. Iyi bvunzo inogona kuratidza kana adrenal glands yako ichigadzira cortisol yakakwana kana kuti haisi kupindura zvakanaka kune zviratidzo zvehomoni.

Vanachiremba vanowanzo shandisa bvunzo iyi kana vachifungidzira mamiriro akaita seAddison's disease, uko adrenal glands yako isingagadziri cortisol yakakwana. Vanogonawo kuishandisa kutarisa secondary adrenal insufficiency, iyo inoitika kana pituitary gland yako isingatumire zviratidzo zvakanaka kune adrenal glands yako.

Dzimwe nguva, chiremba wako anogona kukurudzira bvunzo iyi kana wanga uchitora mishonga yema steroid kwenguva refu. Kushandiswa kwenguva refu kwema steroid dzimwe nguva kunogona kukanganisa kuti sisitimu yako yehomoni yechisikigo inoshanda sei, uye bvunzo iyi inobatsira kuona kana adrenal glands yako yapora basa ravo rakajairika.

Cosyntropin Inoshanda Sei?

Cosyntropin inoshanda nekufanana nekuita sekufona kunomutsa zvinyoro nyoro kumaguru ako eadrenal. Kana yakajekeswa, inofamba nemuropa rako uye inosungirira kune zvakakosha zvinogamuchira pamaguru ako eadrenal, sekungaita ACTH yechisikigo.

Kusungirira uku kunomutsa maguru ako eadrenal kuti abudise cortisol muropa rako. Mune vanhu vane hutano, mazinga e cortisol anofanira kukwira zvakanyanya mukati memaminitsi makumi matatu kusvika makumi matanhatu mushure mejekiseni. Chiremba wako achatora mienzaniso yeropa pamberi uye mushure mejekiseni kuyera kuti maguru ako eadrenal akaburitsa cortisol yakawanda sei.

Muedzo uyu unoonekwa seakavimbika nekuti cosyntropin inosimudzira yakasimba yekugadzirwa kwe cortisol. Kana maguru ako eadrenal achishanda zvakajairika, anofanira kupindura zvakasimba kuhomoni iyi yekugadzira.

Ndingatora Sei Cosyntropin?

Hauzozvitore iwe pachako cosyntropin - inogara ichipiwa nenyanzvi yehutano munzvimbo yekurapa. Jekiseni rinowanzoitwa mumhasuru (intramuscular) kana mutsinga (intravenous), zvichienderana nezvinofarirwa nachiremba wako uye rudzi rwemuedzo waunenge uchiita.

Mberi kwemuedzo wako, haufanirwe kutsanya kana kudzivisa kudya, asi chiremba wako angakukumbira kuti udzivise mishonga yakati wandei kwemazuva mashoma. Zvimwe zvinodhaka, kunyanya ma steroids, zvinogona kukanganisa mhedzisiro yemuedzo, saka zvakakosha kuti uudze chiremba wako nezve mishonga yese yaunotora.

Jekiseni pacharo rinowanzo kurwadza kupfuura kupfura kwakajairika. Unogona kunzwa kubaya zvishoma kana tsono yapinda, asi kusagadzikana kunopfuura nekukurumidza. Mushure mejekiseni, unozofanira kugara munzvimbo yekurapa kweawa imwe kuitira kuti chiremba wako atore mienzaniso yeropa yekutevera.

Ndingatora Cosyntropin Kwenguva Yakareba Sei?

Cosyntropin inoshandiswa kamwe chete panguva yemuedzo wako wekuongorora - haisi mushonga waunotora nguva dzose kana nekufamba kwenguva. Maitiro ese ekuongorora anowanzo tora anenge awa imwe kusvika kumaawa maviri kubva pakutanga kusvika kumagumo.

Chiremba wako achakupa jekiseni wobva watevedzera mhinduro yako nekutora mienzaniso yeropa panguva dzakatarwa. Kazhinji, vachatora mienzaniso pamaminitsi makumi matatu nemakumi matanhatu mushure mejekiseni kuti vaone kuti mazinga ako e cortisol anoshanduka sei.

Kana chiremba wako achida kudzokorora bvunzo nechikonzero chipi zvacho, vachaironga semusangano wakasiyana. Izvi zvinogona kuitika kana mhedzisiro yekutanga yebvunzo isina kujeka kana kana vachida kuteedzera kushanda kwegland yako ye adrenal nekufamba kwenguva.

Ndezvipi Zvipingamupinyi zveCosyntropin?

Vanhu vazhinji vanotsungirira cosyntropin zvakanaka, uye zvipingamupinyi zvakakomba hazviwanzoitiki. Zvipingamupinyi zvakajairika zvakapfava uye zvenguva pfupi, kazhinji zvinogara maawa mashoma mushure mejekiseni.

Heano zvipingamupinyi zvaungasangana nazvo, kutanga neizvo zvakajairika:

• Kunyara kudiki kana kusagadzikana mudumbu
• Dzungu diki kana kunzwa kusimba mumusoro
• Kutsva kwenguva pfupi kana kudziya pachiso chako
• Kutsamwa kudiki panzvimbo yejekiseni
• Kurwadziwa kwemusoro kudiki

Izvi zvipingamupinyi zvakajairika zvinowanzoenda zvega mukati memaawa mashoma uye hazvidi chero kurapwa kwakakosha.

Zvimwe zvipingamupinyi zvakakomba hazviwanzoitiki asi zvinogona kusanganisira mhinduro dzekurwara. Heano zviratidzo zvisingawanzoitiki asi zvinonyanya kukosha zvekutarisa:

• Mhinduro dzakakomba dzekurwara nekufema kwakaoma kana kuzvimba
• Kurova kwemoyo nekukurumidza kana kusina kujairika
• Dzungu rakanyanya kana kufenda
• Kunyara kwakanyanya kana kurutsa
• Kurwadziwa muchipfuva kana kusimba

Kana iwe ukasangana nechero zviratidzo izvi zvakakomba, timu yako yezvokurapa ichazvigadzirisa nekukasira. Ichi ndicho chikonzero nei bvunzo ichigara ichiitwa munzvimbo yezvokurapa uko rubatsiro runowanikwa nyore nyore.

Ndiani Asingafaniri Kutora Cosyntropin?

Cosyntropin inowanzoita seyakanaka kune vanhu vazhinji, asi pane dzimwe nguva apo chiremba wako angasarudza imwe nzira yekuyedza kana kutora matanho ekuwedzera panguva yebvunzo.

Unofanira kuudza chiremba wako kana uine chero chimwe chezvinhu izvi usati wapiwa cosyntropin:

• Kuziva kusawirirana necosyntropin kana mishonga yakafanana
• Matambudziko emoyo akakomba kana kurwisa kwemoyo kwemazuva ano
• High blood pressure isingadzorwi
• Zvirwere zvinoshanda kana kurwara kwakakomba
• Kuzvitakura kana kuyamwisa

Chiremba wako achanyatso kuyera mabhenefiti nenjodzi kana uine chero chimwe chezvinhu izvi. Muzviitiko zvakawanda, vanogona kuramba vachiita bvunzo zvakachengeteka nekutarisa kwakakodzera uye matanho ekudzivirira.

Kana uri kutora mishonga yakati wandei, kunyanya ma steroids kana zvinodhaka zvinokanganisa mahomoni, chiremba wako angangokukumbira kuti uzvimise kwenguva pfupi usati waita bvunzo. Izvi zvinobatsira kuona mhedzisiro yakanyatsojeka inogoneka.

Mazita eCosyntropin Brand

Cosyntropin inowanikwa pasi pemazita akati wandei emhando, Cortrosyn ndiyo inonyanya kushandiswa muUnited States. Unogona zvakare kusangana nayo pasi pemazita akaita seSynacthen mune dzimwe nyika.

Zvisinei nezita remhando, ese mavhezheni ecosyntropin ane chinhu chimwe chete chinoshanda uye anoshanda nenzira imwechete. Chiremba wako kana pharmacy vachakuzivisa kuti ndeipi mhando yavanoshandisa pabvunzo yako.

Cosyntropin Alternatives

Nepo cosyntropin iri mushonga unonyanya kushandiswa kuyedza basa re adrenal, kune dzimwe nzira dzaungafunga nezvazvo chiremba wako mune dzimwe nguva.

Bvunzo yekushivirira insulin imwe nzira yekutarisa basa re adrenal, asi yakaoma uye inotakura njodzi dzakakwirira. Chiremba wako angashandisawo mamwe bvunzo dzeropa kana zvidzidzo zve imaging kuti aongorore adrenal glands yako, zvichienderana nemamiriro ako chaiwo.

Mune zvimwe zviitiko, chiremba wako angakurudzira kutarisa mazinga ako echisikigo e cortisol zuva rese pane kushandisa bvunzo yekukurudzira. Iyi nzira inogona kubatsira kana mhedzisiro yebvunzo ye cosyntropin isina kujeka kana kana usingakwanise kuwana jekiseni zvakachengeteka.

Ko Cosyntropin Zviri Nani Kupfuura Zvimwe Zviedzo ZveAdrenal Function?

Kuedzwa kweCosyntropin kunoonekwa seyakajairika yegoridhe yekucherechedza kusakwana kweadrenal yekutanga nekuti zvose zviri zviviri zvakarurama uye zvakachengeteka. Inopa mhedzisiro yakajeka, yakavimbika iyo inobatsira vanachiremba kuita zvirwere zvine chivimbo.

Kana ichienzaniswa nezvimwe zviedzo zvakaita se insulin tolerance test, cosyntropin yakachengeteka zvikuru uye iri nyore kuita. Insulin tolerance test inogona kukonzera njodzi yakaderera yeropa, nepo cosyntropin isingawanzo kukonzera matambudziko akakomba.

Cosyntropin test inonyanya kukodzera kupfuura kuyera mazinga echisikigo e cortisol zuva rese, izvo zvinoda kubviswa kweropa kwakawanda uye zvinogona kukanganiswa nekushushikana, kurwara, kana mabasa ezuva nezuva. Nekosyntropin, chiremba wako anowana mufananidzo wakajeka weadrenal yako function mukushanya kumwe chete.

Mibvunzo Inowanzo Bvunzwa Nezve Cosyntropin

Cosyntropin Yakachengeteka Kune Vanhu vane Chirwere Chemoyo Here?

Cosyntropin inogona kushandiswa zvakachengeteka muvanhu vane chirwere chemoyo, asi chiremba wako achatora matanho ekuwedzera panguva yekuedzwa. Vachatarisa kurova kwemoyo wako uye ropa zvakanyanya uye vanogona kuve nemidziyo yekukurumidzira yakagadzirira.

Kana uine matambudziko akakomba emoyo kana uine chirwere chemoyo munguva pfupi yapfuura, chiremba wako angangozvitarisa kusvikira mamiriro ako akagadzikana. Vachagara vachiyera kukosha kwekuwana mhedzisiro yekuedzwa pamusoro pechero njodzi dzinogona kune hutano hwako.

Ndoitei Kana Ndikanzwa Kusagadzikana Mushure meCosyntropin Injection?

Kana iwe ukanzwa usina kunaka mushure mekuwana cosyntropin, udza timu yako yehutano nekukasira. Yeuka kuti iwe uchave uri muchipatara panguva uye mushure mekuongorora, saka rubatsiro runogara ruri pedyo.

Zviratidzo zvishoma zvakaita sekuona kusagadzikana kana dzungu zvakajairika uye zvinowanzoenda nekukurumidza. Zvisinei, kana iwe ukaona zviratidzo zvakakomba zvakaita sekufema zvakaoma, kurwadziwa muchipfuva, kana dzungu rakanyanya, timu yako yekurapa ichapa kurapwa nekukasira.

Ndingatyaira Kumba Mushure meCosyntropin Test here?

Vanhu vazhinji vanogona kutyaira kumba mushure mecosyntropin test, asi izvi zvinoenderana nekuti unonzwa sei mushure mejekiseni. Kana ukaona dzungu kana kusanzwa zvakanaka zvachose, zvakachengeteka kuti mumwe munhu akutyairire kumba.

Vashandi vehutano vako vachaita shuwa kuti unonzwa wakagadzikana usati wabva panzvimbo iyi. Vachakupawo mirairo yekuti uone chii uye kuti ungadaidzira riini kana uine chero zvinokunetsa gare gare.

Mibairo yeCosyntropin Test Yakanyatsojeka Sei?

Cosyntropin tests akanyatsojeka pakuongorora primary adrenal insufficiency, vachiziva zvakarurama mamiriro acho mune angangoita 95% yezviitiko. Muedzo uyu unovimbika zvakanyanya kana waitwa nemazvo uye kana usiri kutora mishonga inogona kukanganisa mibairo.

Zvisinei, muedzo uyu hauvimbike zvakanyanya pakuongorora secondary adrenal insufficiency, kunyanya kana mamiriro acho akagadzirwa nguva pfupi yadarika. Muzviitiko izvi, chiremba wako angangoda mamwe maedzo kana angangodzokorora cosyntropin test mushure mekunge nguva yakwana.

Ndingada Kudzokorora Cosyntropin Test here?

Vanhu vazhinji vanongoda imwe cosyntropin test kuti vawane kuongororwa kwakajeka. Zvisinei, chiremba wako angakurudzira kudzokorora muedzo kana mibairo yekutanga yaive pamuganhu kana isina kujeka.

Ungadawo kudzokorora miedzo kana wakabatwa nezvinetso zveadrenal uye chiremba wako achida kutarisa kuti kurapwa kwako kuri kushanda sei. Vamwe vanhu vanoda kuongororwa nguva nenguva kweadrenal function yavo nekufamba kwenguva, kunyanya kana vachipora kubva kumamiriro akakanganisa hurongwa hwavo hwemahomoni.