Chii chinonzi Daclatasvir: Zvinoshandiswa, Madosi, Migumisiro uye Zvimwe

Daclatasvir mushonga unodzivirira mavhairasi wakagadzirirwa kurapa hepatitis C, hutachiona hunokonzerwa nemavhairasi hunokanganisa chiropa chako. Mushonga uyu unopiwa nachiremba unobva kuboka remishonga inonzi direct-acting antivirals, iyo inoshanda nekudzivirira mavhairasi kuti asawedzere mumuviri wako. Kunyange zvazvo daclatasvir yaichimboshandiswa pamwe chete nemimwe mishonga yehepatitis C, nzira itsva dzekurapa dzakatsiva zvakanyanya mumapurogiramu mazhinji ekurapa nhasi.

Chii chinonzi Daclatasvir?

Daclatasvir mushonga unodzivirira mavhairasi unovavarira kurwisa hepatitis C virus (HCV) nekukanganisa protein chaiyo inodiwa nevairasi kuti ibereke. Fungidzira sekiyi inovharira rimwe remabasa akakosha evairasi, ichidzivirira kuti isagadzire makopi ayo mumaseru ako echiropa.

Mushonga uyu wakagadzirwa sechikamu cheshanduko mukurapa hepatitis C iyo yakabva kune dzakare, dzakaomarara kurapa. Daclatasvir inonyanya kuvavarira protein yeNS5A, iyo yakakosha pakukwanisa kwevairasi kubereka uye kuunganidza zvikamu zvitsva zvevairasi.

Mushonga uyu unogara uchishandiswa pamwe chete nemimwe mishonga yehepatitis C nekuti kushandisa mishonga yakawanda pamwe chete kunonyanya kushanda pane kushandisa mushonga mumwe chete. Iyi nzira yekubatanidza inobatsira kuona kuti mavhairasi haagadziri kuramba kurapwa.

Chii chinonzi Daclatasvir chinoshandiswa?

Daclatasvir inoshandiswa kurapa hutachiona husingaperi hwehepatitis C virus muvanhu vakuru. Chiremba wako anogona kuunyora kana uine mamwe marudzi ehepatitis C, kunyanya genotype 3, kunyange zvichigona kushanda kune mamwe ma genotypes zvakare.

Mushonga uyu unowanzo kurudzirwa kune vanhu vasina kurapwa hepatitis C kare, pamwe nevaya vakaedza mamwe marapirwo asina kushanda. Inoshandiswawo kune varwere vane cirrhosis yechiropa (kukuvara) kunokonzerwa nehepatitis C, kunyange izvi zvichida kutariswa zvakanyanya.

Mune dzimwe nguva, vanachiremba vanonyora daclatasvir kuvashandi vane zvese hepatitis C uye HIV infections. Nzira yekurapa iyi inobatsira kubata zvese zvirwere panguva imwe chete uku ichideredza njodzi yekudyidzana kwemishonga.

Daclatasvir Inoshanda Sei?

Daclatasvir inoshanda nekunangana nekudzivisa protein yeNS5A, iyo hepatitis C virus inoda kuti iwedzere uye ipararire muropa rako. Kana protein iyi yakavharwa, virus haigone kupedzisa hupenyu hwayo uye inozofa.

Mushonga uyu unoonekwa seune simba zvishoma pauri wega, ndosaka uchigara uchibatanidzwa nemimwe mishonga inorwisa mavhairasi. Kubatanidzwa uku kunogadzira kurapwa kwakasimba kunorwisa virus kubva kumativi akawanda, zvichiita kuti zvisakwanise kuti virus ipone kana kuita kuramba.

Mishonga inoshanda nekukurumidza, nevashandi vazhinji vachiona kudonha kukuru mumutoro wavo wevairasi mukati memavhiki mashoma ekutanga ekurapa. Zvisinei, kupedzisa nzira yakazara yekurapa kwakakosha kuti uve nechokwadi chekuti virus inobviswa zvachose kubva muhurongwa hwako.

Ndingatora Sei Daclatasvir?

Tora daclatasvir sezvakanyorwa nachiremba wako, kazhinji kamwe pazuva uine kana usina chikafu. Madosi akajairika anowanzoita 60mg pazuva, kunyangwe chiremba wako angachinja izvi zvichienderana nemimwe mishonga yaunotora kana mamiriro ako chaiwo ekurapa.

Unogona kutora mushonga uyu nemvura, mukaka, kana muto, uye hazvina basa kuti unoutora nezvokudya kana mudumbu risina chinhu. Zvisinei, edza kuutora panguva imwe chete zuva rega rega kuti uchengetedze mazinga akagadzikana muropa rako.

Kana uri kutora mimwe mishonga, kunyanya mimwe mishonga yeHIV, chiremba wako angaderedza daclatasvir yako kusvika 30mg pazuva. Usambofa wakachinja madosi ako wega, sezvo izvi zvingakanganisa kuti kurapwa kunoshanda sei.

Momedza piritsi rose risina kupwanya, kutsenga, kana kuputsa. Kana uine dambudziko rekumedza mapiritsi, taura nachiremba wako nezve dzimwe nzira kana nzira dzinogona kubatsira.

Ndinofanira Kutora Daclatasvir Kwenguva Yakareba Sei?

Vanhu vazhinji vanotora daclatasvir kwemavhiki gumi nemaviri (anenge mwedzi mitatu) sechikamu chekurapa kwavo hepatitis C. Zvisinei, nguva yako yekurapa inogona kusiyana zvichienderana nemamiriro ako chaiwo, kusanganisira rudzi rwehepatitis C yaunayo uye kana uine cirrhosis.

Vamwe varwere vangangoda mavhiki makumi maviri nemana ekurapa, kunyanya kana vaine chirwere chechiropa chakanyanya kana vakaedza dzimwe nzira dzekurapa hepatitis C kare. Chiremba wako achasarudza urefu hwakakodzera hwekurapa zvichienderana nenhoroondo yako yezvokurapa uye mhinduro yekurapa.

Zvakakosha kupedzisa nzira yese yekurapa, kunyangwe ukatanga kunzwa zviri nani kana bvunzo dzako dzemurabhoritari dzichiratidza kuti hutachiona hahuwanikwe. Kumisa kurapa nekukurumidza kunowedzera zvakanyanya njodzi yekuti hutachiona huchadzoka uye hunogona kuita kuti kurapwa kwemunguva yemberi kusashanda zvakanaka.

Ndezvipi Zvipingamupinyi zveDaclatasvir?

Vanhu vazhinji vanotsungirira daclatasvir zvakanaka, asi semishonga yese, inogona kukonzera zvipingamupinyi. Mashoko akanaka ndeokuti zvipingamupinyi zvakakomba hazviwanzoitiki, uye vanhu vazhinji vanogona kupedzisa kurapwa kwavo vasina matambudziko makuru.

Heano zvipingamupinyi zvakajairika zvaungasangana nazvo uchitora daclatasvir:

• Kutemwa nemusoro uye kuneta
• Nausea uye kurutsa dzimwe nguva
• Diarhea kana kuvharika
• Dizziness kana lightheadedness
• Kutadza kurara
• Mild skin rash kana itching

Izvi zvipingamupinyi zvakajairika zvinowanzoita nani sezvo muviri wako uchigadzirisa kumishonga uye kazhinji haidi kumisa kurapa.

Zvimwe zvipingamupinyi zvakakomba hazviwanzoitiki asi zvinoda kutariswa kwekurapa nekukurumidza. Izvi zvinosanganisira:

• Kusangana nekurwara zvakanyanya nekufema kwakaoma kana kuzvimba
• Kuchinja kusinganzwisisike mumoyo
• Zviratidzo zvematambudziko echiropa sekusvava kweganda kana weti yakasviba
• Kushungurudzika kwakanyanya kana pfungwa dzekuzvikuvadza
• Kurwadziwa kwakanyanya kunodzivirira kudya

Kana ukaona chero zviratidzo izvi zvakakomba, taura nachiremba wako nekukasira kana kutsvaga rubatsiro rwekurapa nekukurumidza.

Ndiani Asingafaniri Kutora Daclatasvir?

Daclatasvir haikodzeri munhu wese, uye chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akuisa pamushonga uyu. Hau faniri kutora mushonga uyu kana uine allergic ku daclatasvir kana chero zvinhu zvayo.

Mamwe mamiriro ekurapa anoda kufunga kwakakosha kana anogona kukudzivirira kutora daclatasvir zvakachengeteka. Izvi zvinosanganisira:

• Kusangana nechirwere chechiropa chakanyanya kupfuura hepatitis C
• Mamwe matambudziko emoyo
• Kusangana nechirwere cheitsvo chakanyanya chinoda dialysis
• Kushandisa zvinodhaka zvakanyanya zvinogona kukanganisa kurapwa
• Kuzvitakura kana kuronga kuva nepamuviri

Vanhu vari kutora mimwe mishonga vanogonawo kudzivisa daclatasvir kana kuti zviyero zvavo zvinofanirwa kuchinjwa zvakanyatso kudzivirira kusangana kunotyisa.

Kana uine pamuviri kana kuyamwisa, taura nezve njodzi nemabhenefiti nachiremba wako. Kunyange daclatasvir pachayo isingakuvadzi mwana ari kukura, inowanzo sanganiswa nemimwe mishonga inogona kuva nematambudziko panguva yekuzvitakura.

Mazita eDaclatasvir Brand

Daclatasvir inowanikwa pasi pezita rekuti Daklinza munyika zhinji, kusanganisira United States. Iri ndiro zita rinonyanya kuzivikanwa remushonga uyu pasi rose.

Mune dzimwe nzvimbo, unogona kuwana daclatasvir ichitengeswa pasi pemazita akasiyana emhando kana sechikamu chemapiritsi akasanganiswa anosanganisira mamwe mishonga yehepatitis C. Nguva dzose bvunza chiremba wako wemishonga kuti uve nechokwadi chekuti uri kuwana mushonga wakarurama nesimba.

Mhando dzakajairika dzedaclatasvir dzinogona kuwanikwa mune dzimwe nyika, izvo zvinogona kubatsira kuderedza mari yekurapa. Zvisinei, gara uchishandisa zita chairo kana vhezheni yakajairika iyo chiremba wako anoraira, sezvo vagadziri vakasiyana vangave nemafomu akasiyana zvishoma.

Zvimwe Zvinhu Zvokutsiva Daclatasvir

Mishonga mitsva yakati wandei yehepatitis C yave kuwanikwa iyo inogona kuve yakasununguka kana kushanda zviri nani pane daclatasvir-based regimens. Zvimwe zvinhu zvokutsiva izvi zvinosanganisira mapiritsi akasanganiswa ane mishonga yakawanda mune piritsi rimwe chete, zvichiita kuti kurapwa kuve nyore.

Zvimwe zvinhu zvakajairika zvingafungwa nachiremba wako zvinosanganisira:

• Sofosbuvir/velpatasvir (Epclusa)
• Glecaprevir/pibrentasvir (Mavyret)
• Sofosbuvir/ledipasvir (Harvoni)
• Elbasvir/grazoprevir (Zepatier)

Mishonga mitsva iyi inowanzoita mashoma mativi, nguva pfupi yekurapa, kana mitengo iri nani yekushanda pane yekare daclatasvir-based combinations.

Chiremba wako achasarudza nzira yakanakisisa yekurapa zvichienderana nehepatitis C genotype yako, nhoroondo yako yezvokurapa, mamwe mishonga yaunotora, uye mamiriro ako ega. Mari uye inishuwarenzi inogonawo kukanganisa sarudzo yekurapa.

Ko Daclatasvir Ari Nani Pane Sofosbuvir Here?

Daclatasvir na sofosbuvir vanoshanda zvakasiyana uye vanowanzo shandiswa pamwechete panzvimbo pekuenzaniswa sezvinhu zviri kukwikwidzana. Sofosbuvir inovharira chikamu chakasiyana chehupenyu hwehepatitis C virus, zvichiita kuti mishonga miviri iyi ive inowedzerana panzvimbo pekuita zvemakwikwi.

Kana zvasanganiswa, daclatasvir na sofosbuvir vanogadzira musanganiswa une simba unoshanda zvakanyanya kurwisa hepatitis C. Musanganiswa uyu une mitengo yekurapa ye90% kana kupfuura mune vazhinji varwere, izvo zvakanaka zvikuru pakurapa hepatitis C.

Asi, kurapwa kutsva kwakabatanidzwa uko kunobatanidza mishonga yakawanda mumapiritsi rimwe chete kwave kuchizivikanwa nekuti kuri nyore uye dzimwe nguva kunoshanda zvakanyanya. Zvinhu izvi zvitsva zvingave zvakanaka kune varwere vakawanda kupfuura musanganiswa we daclatasvir-sofosbuvir.

Chiremba wako achakubatsira kunzwisisa kuti ndeipi nzira yekurapa iri nani kune mamiriro ako chaiwo, achifunga nezvezvinhu zvakaita se hepatitis C genotype yako, nhoroondo yako yekurapa, uye zvaunofarira pakurapa.

Mibvunzo Inowanzo Bvunzwa Pamusoro peDaclatasvir

Q1. Daclatasvir Yakachengeteka Kune Vanhu vane Chirwere cheItsvo here?

Daclatasvir inogona kushandiswa zvakachengeteka muvanhu vane chirwere cheitsvo chinyoro kusvika pakati nepakati, sezvo itsvo dzisingabvise zvakawanda zvemushonga uyu mumuviri wako. Zvisinei, vanhu vane chirwere cheitsvo chakakomba kana avo vari pa dialysis vanoda kutariswa zvakanyanya uye zvichida dzimwe nzira dzekurapa.

Chiremba wako achatarisa kushanda kweitsvo dzako usati watanga kurapwa uye anogona kuzvitarisa panguva yekurapa. Kana uine matambudziko eitsvo, ita shuwa kuti unozivisa mupi wako wehutano kuti vagadzirise chirongwa chako chekurapa zvinoenderana.

Q2. Ndingaita Sei Kana Ndikatora Daclatasvir yakawandisa netsaona?

Kana netsaona ukatora daclatasvir yakawanda kupfuura yakarairwa, taura nachiremba wako kana nzvimbo yekudzora muchetura nekukasira. Kunyange zvazvo overdoses yakakomba isingawanzoitiki, kutora zvakawanda zvingawedzera njodzi yako yemigumisiro kana matambudziko emoyo.

Usaedze kutsiva overdose nekusvetuka mushonga wako unotevera. Pane kudaro, tevera mirairo yachiremba wako nezvekuti ungadzokera riini kune yako yakajairika dosing schedule. Chengeta zvaunenge watora dose yakawedzerwa kuti ubatsire mupi wako wehutano kuongorora chero njodzi.

Q3. Ndingaita Sei Kana Ndikakanganwa Dose yeDaclatasvir?

Kana ukakanganwa dose ye daclatasvir, itore paunenge uchiziva, kunze kwekunge yava nguva yechikamu chako chinotevera. Muchiitiko ichocho, svetuka dose yakakanganwa uye uenderere mberi nechirongwa chako chetsika.

Usambofa wakatora zvikamu zviviri panguva imwe chete kuti uzadze chikamu chawakakanganwa, sezvo izvi zvingawedzera njodzi yako yekuwana mhedzisiro. Kana ukakanganwa zvikamu kazhinji, funga kuisa zviyeuchidzo zvefoni kana kushandisa chirongwa chemishonga kuti zvikubatsire kuti urambe uri munzira.

Q4. Ndingamira Rini Kutora Daclatasvir?

Mira kutora daclatasvir chete kana chiremba wako akuudza, kazhinji mushure mekupedza nzira yako yakazara yekurapa. Vanhu vazhinji vanoitora kwemavhiki gumi nemaviri kusvika makumi maviri nemana, zvichienderana nemamiriro avo chaiwo.

Chiremba wako achatarisa kufambira mberi kwako nemiedzo yeropa uye achakuzivisa kana zvakachengeteka kumisa kurapwa. Kumisa nekukurumidza, kunyangwe ukanzwa zviri nani, kunogona kubvumira hutachiona hwehepatitis C kudzoka uye kungaita kuti kurapwa kwemunguva yemberi kusashanda zvakanaka.

Q5. Ndinganwa Doro Ndiri Kutora Daclatasvir?

Zvakanakisa kudzivisa doro zvachose uchitora daclatasvir yekurapa hepatitis C. Doro rinogona kukuvadza chiropa chako, icho chakatove pasi pekumanikidzwa kubva kuhutachiona hwehepatitis C, uye zvinogona kukanganisa kugona kwemuviri wako kupora.

Uyezve, doro rinogona kuwedzera mamwe mhedzisiro ye daclatasvir, senge kusvotwa uye kuneta. Chiropa chako chinoda kutarisa pakupora kubva kuhutachiona hwehepatitis C, saka kuchipa zororo kubva mukugadzirisa doro kuchabatsira kutsigira kupora kwako.