Chii chinonzi Dapagliflozin uye Metformin: Zvavanoshandiswa, Dosage, Migumisiro Yemuviri uye Zvimwe Zvakawanda

Dapagliflozin uye metformin mushonga unosanganiswa unobatsira kubata chirwere cheshuga che mhando 2 nekushanda nenzira mbiri dzakasiyana dzekudzikisa mazinga eshuga yeropa. Iyi nzira yekushanda kaviri inogona kushanda zvakanyanya pane kushandisa mushonga mumwe chete, ichikupa kutonga kuri nani pamusoro pechirwere chako cheshuga nekureruka kwekutora mapiritsi mashoma zuva rega rega.

Chii chinonzi Dapagliflozin uye Metformin?

Mushonga uyu unosanganisa mishonga miviri yakaratidza kubatsira kurwisa chirwere cheshuga mupiritsi rimwe chete. Dapagliflozin ndeyeboka remishonga inonzi SGLT2 inhibitors, nepo metformin iri kubva kumhuri ye biguanide yemishonga.

Funga nezvekusanganiswa uku sechikwata chekugadzirisa shuga yako yeropa. Chinhu chimwe nechimwe chinobata dambudziko kubva kune imwe kona, vachishanda pamwechete kubatsira muviri wako kugadzirisa glucose zvakanyanya. Iyi musanganiswa inowanikwa pasi pemazita emhando seXigduo XR muUnited States.

Chiremba wako angangokurudzira kusanganiswa uku kana metformin yega isingapi kutonga kwakakwana kweshuga yeropa, kana kana uchida mabhenefiti emishonga yese asi uchida nyore nyore kwepiritsi rimwe.

Chii chinonzi Dapagliflozin uye Metformin chinoshandiswa?

Iyi musanganiswa wemishonga inonyanya kushandiswa kurapa chirwere cheshuga che mhando 2 muvanhu vakuru. Inobatsira kudzikisa mazinga eshuga yeropa kana kudya uye kurovedza muviri zvoga zvisina kukwana kuchengetedza mazinga eglucose ane hutano.

Mupi wako wehutano angangokurudzira mushonga uyu kana iwe uchitotora metformin asi uchida imwe kutonga kweshuga yeropa. Inorayirwawo kana iwe uchikwanisa kubatsirwa kubva kune zvakasarudzika zvakanakira zvinopihwa ne dapagliflozin, senge kurasikirwa uremu uye kuderedzwa kweropa.

Kupfuura manejimendi eshuga yeropa, vamwe vanhu vanowana mamwe mabhenefiti senge kurasikirwa uremu zvishoma uye kuderedzwa zvishoma kweropa. Zvisinei, izvi zvinosiyana kubva kumunhu nemunhu, uye mushonga haufaniri kushandiswa chete nekuda kwekurasa uremu.

Mashandisirwo Anoita Dapagliflozin ne Metformin?

Mubatanidzwa uyu unoshanda nemaitiro maviri akasiyana anotsinhirana zvakanaka. Metformin inonyanya kushanda muchiropa chako, ichideredza huwandu hweglucose hunogadzirwa nechiropa chako uye ichibatsira tsandanyama dzako kushandisa insulin zvakanyanya.

Dapagliflozin inotora nzira yakasiyana zvachose nekushanda mumatsvo ako. Inovharira protein inonzi SGLT2 iyo inowanzoita kuti itsvo dzako dzitore glucose zvakare muropa rako. Kana protein iyi yakavharirwa, glucose yakawandisa inobviswa nemumugumo wako panzvimbo yekugara muropa rako.

Chiito ichi chine zvikamu zviviri zvinoreva kuti muviri wako unogadzira glucose shoma ukuwo uchibvisa glucose yakawanda, zvichigadzira mubatanidzwa une simba wekudzora shuga yeropa. Mushonga uyu unoonekwa seune simba zvine mwero uye unoshanda, kazhinji uchipa kuvandudzwa kukuru mumazinga eshuga yeropa mukati memavhiki mashoma ekutanga kurapwa.

Ndingatora Sei Dapagliflozin ne Metformin?

Tora mushonga uyu sezvinorayirwa nachiremba wako, kazhinji kamwe chete pazuva nekudya kwako kwemangwanani. Kuitora nekudya kunobatsira kuderedza dumbu rinogumbura, iro rinogona kuva dambudziko ne metformin, uye rinobatsira muviri wako kutora mushonga zvakanaka.

Mamedza piritsi rose nemvura yakazara. Usapwanya, kuputsa, kana kutsenga mapiritsi anoburitswa kwenguva yakareba, sezvo izvi zvinogona kukanganisa mashandisirwo anoita mushonga mumuviri wako. Kana iwe uchitora vhezheni inoburitswa kwenguva yakareba, unogona kuona goko repiritsi risina chinhu mumugumo wako, izvo zvakajairika zvachose.

Usati watora mushonga wako, idya chikafu chakaringana chinosanganisira mamwe macarbohydrates. Izvi zvinobatsira kudzivirira shuga yeropa rako kubva pakuderera zvakanyanya uye kuderedza mukana wekutsamwa kwedumbu. Dzivisa kutora mushonga mudumbu risina chinhu, kunyanya kana uchitanga kurapwa.

Garai muchinwa mvura yakawanda zuva rese. Izvi zvinokosha zvikuru nekuti dapagliflozin inowedzera kuita weti, uye kunwa mvura zvakanaka kunobatsira kudzivirira matambudziko akadai sekupera mvura mumuviri kana zvirwere zvemumugero wemweti.

Ndingatora Dapagliflozin neMetformin kwenguva yakareba sei?

Mishonga iyi inowanzoita kurapwa kwenguva refu yekudzora chirwere cheshuga che mhando 2. Vanhu vazhinji vanoenderera mberi vachii tora chero ichiri kushanda uye ichigamuchirika, izvo zvinowanzoita kwemakore mazhinji kana kusvika pakusingaperi.

Chiremba wako achatarisa mhinduro yako kumushonga kuburikidza nekuongororwa kweropa nguva dzose, kazhinji achitarisa mazinga ako eA1C mwedzi mitatu kusvika kumatanhatu oga oga. Miedzo iyi inobatsira kuona kana mushonga uri kushanda nemazvo uye kana kuchidikanwa kugadzirisa muyero.

Usambomira kutora mushonga uyu kamwechete usina kubvunza chiremba wako. Kumira kamwechete kunogona kukonzera kuti mazinga ako eshuga yeropa akwire, zvichikonzera matambudziko akakomba. Kana uchida kumisa mushonga, chiremba wako achagadzira chirongwa chekukuendesa kune dzimwe nzira dzekurapa zvakachengeteka.

Ndezvipi Zvakaipa zveDapagliflozin neMetformin?

Semishonga yese, iyi musanganiswa inogona kukonzera mhedzisiro, kunyangwe vanhu vazhinji vachigamuchira zvakanaka. Kunzwisisa zvekutarisira kunogona kukubatsira kuti unzwe wakavimbika pamusoro pekurapa kwako uye kuziva nguva yekubata chiremba wako.

Mhedzisiro yakajairika yaungasangana nayo inosanganisira:

• Kuwedzera kuita weti uye nyota (nekuda kwemaitiro e dapagliflozin)
• Kunyara kudiki kana dumbu kusagadzikana, kunyanya kana uchitanga kurapwa
• Manyoka kana zvigaro zvakasununguka (zvinowanzoitika kwenguva pfupi uye zvinovandudzwa nekufamba kwenguva)
• Kuravira kwesimbi mumuromo mako (kubva ku metformin)
• Zvirwere zvemumugero wemweti (zvinowanzoitika muvakadzi)
• Zvirwere zvembiriso, kunyanya muvakadzi

Mhedzisiro iyi inowanzoitika inowanzovandudzika muviri wako sezvaunojaira mushonga, kazhinji mukati memavhiki mashoma ekutanga ekurapa.

Mhedzisiro yakakomba inoda kutariswa kwekurapa nekukurumidza inosanganisira:

• Zviratidzo zve diabetic ketoacidosis (kusvotwa, kurutsa, kurwadziwa mudumbu, kuoma kufema)
• Kushaya mvura kwakanyanya (dizziness, muromo wakaoma, kuderedzwa kwemvura)
• Matambudziko eitsvo (kuzvimba, shanduko mukuyerera kwemvura, kuneta)
• Zvirwere zvakakomba zvegenital (kubuda zvisingawanzoitiki, kukwenya kwakanyanya, kurwadziwa)
• Lactic acidosis (isingawanzoitiki asi yakakomba - kurwadziwa kwemhasuru, kuoma kufema, kurwadziwa mudumbu)

Bata chiremba wako nekukurumidza kana uine chero zviratidzo izvi zvakakomba, sezvo zvingada kupindira kwekurapa nekukurumidza.

Vamwe vanhu vanogona kusangana nematambudziko asingawanzoitiki asi akakomba seFournier's gangrene (chirwere chakakomba chenzvimbo yegenital) kana maitiro akakomba ekuita allergic. Kunyangwe izvi zvisingawanzoitiki, zvakakosha kuziva zviratidzo zvisingawanzoitiki uye kutsvaga rubatsiro rwekurapa kana uine zvinokunetsa.

Ndiani Asingafaniri Kutora Dapagliflozin uye Metformin?

Mushonga uyu hauna kukodzera munhu wese, uye chiremba wako achanyatsoongorora kana zvakakunakira. Mamwe mamiriro ehutano uye mamiriro anoita kuti musanganiswa uyu usachengeteke kana kusakodzera.

Haufanire kutora mushonga uyu kana uine:

• Type 1 diabetes (muviri wako unoda insulin, kwete kubviswa kweglucose)
• Chirwere cheitsvo chakakomba (mushonga unogona kuwedzera basa reitsvo)
• Diabetic ketoacidosis (matambudziko akakomba anoda kurapwa nekukurumidza)
• Kuziva allergy ku dapagliflozin, metformin, kana chero zvinhu zviri mumushonga
• Chirwere chechiropa chakakomba (chinokanganisa maitiro emuviri wako anogadzira metformin)
• Kukundikana kwemoyo kunoda kupinda muchipatara (kunogona kuwedzera njodzi yematambudziko)

Chiremba wako achashandisawo kungwarira kana uine mamiriro anowedzera njodzi yako yematambudziko, sekunge hutachiona hweurinary tract hunowanzoitika, nhoroondo yekuderera kweropa, kana kana uri vakuru uye uri panjodzi yakakura yekushaya mvura mumuviri.

Mamwe mamiriro anoda kumisa mushonga kwenguva pfupi, sekunge pamberi pekuvhiyiwa, panguva yekurwara ne fivha uye kushaya mvura mumuviri, kana kana uchida ruvara rwekuongorora zvirwere.

Mazita eBrand eDapagliflozin uye Metformin

Mishonga iyi yakasanganiswa inowanikwa pasi pemazita akati wandei ebrand, neXigduo XR ndiyo inonyanya kunyorerwa muUnited States. Iyo "XR" inomirira extended-release, zvinoreva kuti mushonga wakagadzirirwa kuburitsa zvishoma nezvishoma zuva rese.

Mamwe mazita ebrand anogona kuwanikwa mune dzimwe nyika, uye shanduro dzakajairika dzemusanganiswa uyu dzinogona kuwanikwa nekufamba kwenguva. Murapi wako wemishonga anogona kukubatsira kunzwisisa kuti ndeipi fomu yaunogamuchira uye kana iri iyo yekukurumidza-kuburitswa kana yakawedzerwa-kuburitswa vhezheni.

Nguva dzose tarisa nachiremba wako kana murapi wemishonga usati wachinja pakati pemazita ebrand kana shanduro dzakajairika, sezvo mafomu akasiyana anogona kuve nekusiyana kudiki mukuyera kana nguva.

Dapagliflozin uye Metformin Zvimwe Zvinhu

Kana musanganiswa uyu usingakukodzere, dzimwe nzira dzinogona kubatsira kubata chirwere chako cheshuga chetype 2 zvinobudirira. Chiremba wako angangofunga nezvemimwe mishonga yakasanganiswa kana kugadzirisa chirongwa chako chekurapa zvichienderana nezvido zvako zvakananga uye mamiriro ehutano.

Mishonga yakasanganiswa imwe inosanganisira empagliflozin ine metformin (Synjardy), canagliflozin ine metformin (Invokamet), kana sitagliptin ine metformin (Janumet). Musanganiswa wega wega une zvishoma zvakasiyana zvinobatsira uye mativi emhedzisiro.

Mupi wehutano hwako angakurudzirawo kutora mishonga yakasiyana, kushandisa metformin yega nemumwe mushonga wechirwere cheshuga, kana kuongorora makirasi akasiyana zvachose emishonga yechirwere cheshuga senge GLP-1 receptor agonists kana insulin kana zvichidikanwa.

Sarudzo yeimwe nzira inoenderana nemamiriro ako ega, kusanganisira basa remapapu ako, hutano hwemoyo, zvinangwa zvekudzora uremu, uye kuti unotsungirira sei mishonga yakasiyana.

Ko Dapagliflozin naMetformin Zviri Nani Pane Metformin Yega?

Kune vanhu vazhinji vane chirwere cheshuga chetype 2, kusanganiswa kwe dapagliflozin uye metformin kunopa kutonga kwakanaka kweshuga yeropa kupfuura metformin yega. Zvidzidzo zvinoratidza kuti kuwedzera dapagliflozin ku metformin kazhinji kunokonzera kuwedzera kweA1C kuderedzwa kwe0.5 kusvika 1.0 muzana mapoinzi.

Kusanganiswa kunopa mabhenefiti kupfuura kutonga kweshuga yeropa ayo metformin yega isingakwanise kupa. Izvi zvinosanganisira kurasikirwa uremu (kazhinji 2-5 mapaundi), kuderedzwa kwemuviri kudzvinyirira, uye zvinogona kubatsira mumoyo izvo vatsvagiri vachiri kudzidza.

Zvisinei, kusanganiswa kunouyawo nemigumisiro yakawanda uye mari iyo metformin yega isina. Kuwedzera kuita weti, njodzi yakakwirira yekutapukirwa kwemugero weti, uye mukana wekupera mvura ndezve chikamu che dapagliflozin.

Chiremba wako achayerera mabhenefiti aya nenjodzi zvichienderana nemamiriro ako ega, kutonga kweshuga yeropa, uye zvinangwa zvehutano hwese kuti aone kana kusanganiswa kwakakodzera kuedza kune yako chaiyo kesi.

Mibvunzo Inowanzo Bvunzwa Nezve Dapagliflozin uye Metformin

Ko Dapagliflozin naMetformin Zvakachengeteka Here Kune Chirwere Chemoyo?

Kusanganiswa uku kunogona kuve kunobatsira kune vanhu vane mamwe marudzi echirwere chemoyo. Zvidzidzo zvinoratidza kuti SGLT2 inhibitors senge dapagliflozin inogona kubatsira kuderedza njodzi yekuvharirwa muchipatara nekuda kwekutadza kwemoyo uye kufa kwemoyo muvanhu vane chirwere cheshuga chetype 2.

Asi, kana uine nhoroondo yekukundikana kwemoyo, chiremba wako achakutarisa zvakanyatsonaka paunotanga mushonga uyu. Muzviitiko zvisingawanzoitiki, vamwe vanhu vanogona kusangana nezviratidzo zvakanyanya zvekusashanda kwemoyo, saka nguva dzose dzekutevera-kuona dzakakosha kuti uve nechokwadi chekuti mushonga uri kubatsira pane kukuvadza hutano hwemoyo wako.

Ndingaita Sei Kana Ndikashandisa Zvakanyanya Dapagliflozin uye Metformin?

Kana ukangoerekana watora zvakawanda kupfuura chiyero chawakanyorerwa, taura nechiremba wako kana nzvimbo yekudzora chepfu nekukasira. Kutora zvakanyanya kunogona kuwedzera njodzi yako yezvinetso zvakakomba zvakadai se lactic acidosis kubva kuchikamu chemetformin kana kupera mvura mumuviri kubva ku dapagliflozin.

Tarisa zviratidzo zvakaita senausea yakakomba, kurutsa, kurwadziwa mudumbu, kufema kwakaoma, kunzwa kurara zvisinganzwisisike, kana zviratidzo zvekupera mvura mumuviri kwakanyanya. Usamirira kuti zviratidzo zviitike usati watsvaga rubatsiro, sezvo zvimwe zvinetso zvinogona kukura nekukurumidza uye zvinoda kutarisirwa kwekurapa nekukasira.

Ndingaita Sei Kana Ndikakanganwa Dose yeDapagliflozin uye Metformin?

Kana ukakanganwa dose, itore paunorangarira, asi chete kana kuchiri mangwanani uye unogona kuitora nechikafu. Kana yatove masikati kana manheru, skip the missed dose and take your next dose at the regular time the following morning.

Usambofa wakatora madosi maviri panguva imwe chete kuti ugadzirise dose yakarasika, sezvo izvi zvinogona kuwedzera njodzi yako yezvinetso. Kana iwe uchikanganwa madosi kazhinji, funga kumisa alarm yezuva nezuva kana kushandisa chirongwa chemapiritsi kuti ikubatsire kurangarira maitiro ako emishonga.

Ndingamira Rini Kutora Dapagliflozin uye Metformin?

Ingomira kutora mushonga uyu pasi pekutungamirirwa nachiremba wako. Kunyangwe mazinga ako e shuga yeropa achivandudza zvakanyanya, kumisa mushonga kamwe kamwe zvinogona kukonzera kuti mazinga ako akwirezve, sezvo chirwere cheshuga che rudzi rwechipiri chiri mamiriro echronic anoda kuramba achitarisirwa.

Chiremba wako angangofunga kuderedza mushonga wako kana kuchinjira kumumwe mushonga kana ukaona matambudziko akakura, kana basa remapapu ako richichinja, kana kana manejimendi ako echirwere cheshuga achida kuchinja nekufamba kwenguva. Chero kuchinja kupi zvako kumishonga yako yechirwere cheshuga kunofanira kugara kuri chikamu chechirongwa chekurapa chakanyatso rongwa.

Ndinganwe Doro Ndiri Kutora Dapagliflozin uye Metformin Here?

Unogona kunwa doro zvine mwero uchitora mushonga uyu, asi unofanira kungwarira zvakanyanya nezvekuongorora shuga yako yeropa uye kugara uine mvura yakakwana mumuviri. Doro rinogona kuwedzera njodzi ye lactic acidosis kana rakasanganiswa ne metformin, kunyanya kana ukanwa zvakanyanya kana kusadya nguva dzose.

Ganhurira kunwa doro kusvika pakunwa kamwe chete pazuva kuvakadzi uye zvinwiwa zviviri pazuva kuvarume, uye gara uchinwa uine chikafu kuti ubatsire kudzivirira shuga yakaderera yeropa. Kana uine nhoroondo yekushandisa doro zvisina kufanira kana matambudziko echiropa, kurukura kunwa doro nemupi wako wehutano, sezvo zvingave zvakanaka kudzivisa zvachose.