Chii chinonzi Digoxin: Zvazvinoshandiswa, Madosi, Migumisiro Yakaipa nezvimwe

Digoxin mushonga wemoyo unobatsira kusimbisa kuita kwemoyo wako uye kudzora rhythm isina kujairika yemoyo. Inobva kumuti wefoxglove uye yakashandiswa zvakachengeteka kwemakumi emakore kurapa mamiriro akasiyana-siyana emoyo kana mamwe marapirwo asina kukwana.

Kana ichipiwa kuburikidza nemarudzi e intramuscular (jekiseni remhasuru) kana intravenous (IV), digoxin inoshanda nekukurumidza kupfuura mafomu emuromo. Iyi nzira yekujekiseni inowanzo shandiswa muzvipatara kana iwe uchida kukurumidza kudzora rhythm yemoyo kana usingakwanise kutora mishonga nemuromo.

Chii chinonzi Digoxin chinoshandiswa?

Digoxin jekiseni rinonyanya kurapa mamiriro maviri makuru emoyo: kukundikana kwemoyo uye atrial fibrillation. Chiremba wako angakurudzira mushonga uyu kana moyo wako uchida rubatsiro rwakawedzerwa kuti upombe ropa zvinobudirira kana rhythm yemoyo wako ikava isina kujairika zvakanyanya.

Nekukundikana kwemoyo, digoxin inobatsira mhasuru dzemoyo wako kuti dzibatane zvakanyanya. Izvi zvinoreva kuti moyo wako unogona kupomba ropa rakawanda nekurova kwega kwega, kuderedza zviratidzo zvakaita sekufema, kuzvimba mumakumbo ako, uye kuneta kunoita kuti mabasa ezuva nezuva ave nematambudziko.

Pakurapa atrial fibrillation, digoxin inoderedza kumhanya kwemoyo wako kune imwe nzira inogoneka. Atrial fibrillation inokonzera makamuri epamusoro emoyo wako kurova zvisina kurongeka, uye digoxin inobatsira kudzorera rhythm yakagadzikana iyo muviri wako unogona kushanda nayo zvakanyanya.

Mumamiriro ezvinhu ekukurumidzira, digoxin inojekiseni inogona kuponesa hupenyu kana mumwe munhu achiwana matambudziko akakomba erhythm yemoyo. Zvikwata zvechipatara zvinoshandisa kana chiito chekukurumidza chichidiwa kugadzirisa rhythm yemoyo inotyisa inogona kutungamira kumatambudziko akakomba.

Kazhinji, majekiseni e digoxin anogona kushandiswa kune mamwe matambudziko erhythm yemoyo senge atrial flutter kana supraventricular tachycardia. Chiremba wako wemoyo achasarudza kana digoxin iri sarudzo chaiyo zvichienderana nemamiriro ako chaiwo emoyo uye hutano hwese.

Digoxin inoshanda sei?

Digoxin inofungidzirwa semushonga wemoyo wakati wandei unoshanda nekuchinja maitiro anoita maseru emoyo wako calcium uye sodium. Inovharisa pombi chaiyo mumaseru ako emhasuru yemoyo, iyo inozopedzisira yaita kuti moyo wako ushande zvine simba uye zvakagadzikana.

Funga nezvemoyo wako semhasuru inoda zviratidzo zvemagetsi zvakakodzera kuti ishande nemazvo. Digoxin inogadzirisa zviratidzo izvi nekukanganisa sodium-potassium pump, iyo inodzora maitiro anoita maseru ako emhasuru yemoyo kuti ashande uye azorore.

Mushonga uyu unokanganisawo tsinga yako ye vagus, iyo yakaita semabhureki echisikigo emoyo wako. Nekukurudzira tsinga iyi, digoxin inobatsira kuderedza kumhanya kwemoyo wako, ichipa moyo wako nguva yakawanda yekuzadzwa neropa pakati pekubhawa.

Kusiyana nemimwe mishonga yemoyo inoshanda mumaminitsi, digoxin inovaka mumuviri wako nekufamba kwenguva. Fomu rinobaiwa rinotanga kushanda mukati memaminitsi makumi matatu kusvika kumaawa maviri, asi zvinogona kutora mazuva akati wandei kuti asvike pakukwana kwavo mumuviri wako.

Ndingatora sei Digoxin Majekiseni?

Majekiseni eDigoxin anogara achipiwa nevashandi vehutano vakadzidziswa munzvimbo dzekurapa dzakadai sezvipatara kana makiriniki. Hauzofaniri kunetseka nezvekuzvipa majekiseni aya kumba, sezvo achida kutariswa zvakanyanya uye kuyera kwakaringana.

Kuti utore intravenous, mushonga unoenda zvakananga muropa rako kuburikidza neIV line. Chikwata chehutano chichaijekesa zvishoma nezvishoma kwemaminitsi akati wandei kudzivirira shanduko dzemoyo wako dzinogona kuva nenjodzi.

Majekiseni eIntramuscular anoenda mumhasuru hombe, kazhinji muruoko rwako rwekumusoro kana chidya. Iyi nzira haisi yakajairika asi inogona kushandiswa kana IV access yakaoma kana kana chiyero chekunyudzwa zvishoma zvishoma chichidiwa.

Usati watora digoxin, timu yako yekurapa ichatarisa basa rako reitsvo uye mazinga e electrolyte. Zvinhu izvi zvinokanganisa maitiro anoita muviri wako mushonga, uye kugadzirisa kunogona kudiwa kuti uve nechokwadi chekuchengeteka kwako.

Hamufaniri kudzivisa chikafu kana zvinwiwa musati mapiwa majekiseni e digoxin. Zvisinei, kuchengetedza tsika yekudya nguva dzose kunobatsira muviri wenyu kugadzirisa mushonga uyu nenzira inotarisirwa kana muchichinjira kumhando dzemuromo.

Ndingatora Digoxin Kwenguva Yakareba Sei?

Kureba kwenguva yekurapwa ne digoxin kunosiyana zvakanyanya zvichienderana nemamiriro ako emoyo uye kuti unopindura sei kumushonga. Vamwe vanhu vanoiisa kwemavhiki mashoma panguva yekukundikana kwemoyo, nepo vamwe vachigona kuda kurapwa kwenguva refu nezvinetso zvisingaperi.

Nekukundikana kwemoyo kwakanyanya kana matambudziko erhythm, unogona kupiwa majekiseni e digoxin kwemazuva mashoma muchipatara. Kana mamiriro ako agadziriswa, chiremba wako anogona kuchinjira kune digoxin yemuromo kana mamwe mishonga yemoyo yaunogona kutora kumba.

Kana uine atrial fibrillation isingaperi, unogona kuda digoxin kwemwedzi kana kunyange makore. Chiremba wako wemoyo achatarisa basa remoyo wako nguva dzose uye mazinga eropa kuti ave nechokwadi chekuti mushonga uyu unoramba uchibatsira pasina kukonzera matambudziko.

Chiremba wako haazombomisa digoxin kamwe kamwe, kunyanya kana wanga uchiiisa kwenguva yakareba. Vachaderedza zvishoma nezvishoma muyero wako vachitarisa moyo wako kudzivirira chero mhedzisiro inogona kuwedzera mamiriro ako.

Ndezvipi Zvakaipa ZveDigoxin?

Zvakajairika zvinokonzeresa digoxin zvinowanzoita zvinyoro uye zvinogoneka, kunyangwe zvakakosha kuziva. Vanhu vazhinji vanowana matambudziko mashoma kana mushonga uyu ukapiwa muyero nemazvo uye uchitariswa zvakanaka.

Zvakanyanya kuwanda zvinokonzeresa zvaungacherechedza zvinosanganisira kusvotwa, kurasikirwa nechido, uye kunzwa kusagadzikana. Zviratidzo izvi zvinowanzoitika kana mazinga e digoxin muropa rako akakwira zvakanyanya, ndosaka bvunzo dzeropa dzenguva dzose dzakakosha.

Heano mativi akajairika anokanganisa vanhu vazhinji vachitora digoxin:

• Kurwadziwa mudumbu nekutsvuka
• Kushaya chido chekudya
• Manyoka
• Kurwadziwa nemusoro
• Dzungu
• Kuneta kana kushaya simba
• Kusaona zvakanaka kana kuona zvinhu zvine ruvara rweyero

Zviratidzo izvi zvinowanzoita nani muviri wako paunojaira mushonga kana kana chiyero chako chachinjwa. Chikwata chako chehutano chichashanda newe kuti chiwane chiyero chakakodzera pakati pekubudirira uye kugadzikana.

Zvimwe zvinokonzera zvisina kunaka hazviwanzoitiki asi zvinoda kutariswa kwekurapa nekukurumidza. Izvi zvinowanzoitika kana mazinga e digoxin akwira zvakanyanya muropa rako, mamiriro anonzi digoxin toxicity.

Zvimwe zvinokonzera zvisina kunaka zvinoda kutariswa kwekurapa nekukurumidza zvinosanganisira:

• Kurwadziwa mudumbu kwakanyanya nekutsvuka
• Kuvhiringidzika kana kuchinja kwepfungwa
• Kurova kwemoyo kusingaite kana kurova kwemoyo kwakanyanya
• Dzungu rakanyanya kana kufenda
• Kurwadziwa muchipfuva
• Kukanganiswa kwakanyanya kwekuona

Kana ukaona chero chimwe chezviratidzo izvi, taura nemupi wako wehutano nekukurumidza kana kutsvaga rubatsiro rwekukurumidza. Kuita nekukurumidza kunogona kudzivirira matambudziko akakomba kubva ku digoxin toxicity.

Zvisingawanzoitiki asi zvakakomba zvinokonzera zvisina kunaka zvinosanganisira kusagadzikana kwemoyo kwakanyanya kunogona kuisa hupenyu panjodzi. Izvi zvinowanzoitika muvanhu vasingasviki 1% vanotora digoxin asi zvinonyanya kuitika kana basa reitsvo risina kunaka kana kana mamwe mishonga achikanganisa kugadzirisa digoxin.

Ndiani Asingafaniri Kutora Digoxin?

Vamwe vanhu havagone kutora digoxin zvakachengeteka nekuda kwekuwedzera njodzi yematambudziko akakomba. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa uye mamiriro ako ehutano azvino usati wanyora mushonga uyu.

Haufaniri kugamuchira digoxin kana uine ventricular fibrillation, kurova kwemoyo kunotyisa hupenyu uko makamuri ezasi emoyo wako anodedera panzvimbo yekupomba. Digoxin inogona kuwedzera mamiriro aya uye kuita kuti zvinyanye kuoma kurapa.

Vanhu vane zvirwere zvemwoyo zvakati wandei vanoda kungwarira zvakanyanya kana vasingakwanise kutora digoxin zvachose. Izvi zvinosanganisira avo vane heart block, uko masaini emagetsi haafambi zvakanaka mumoyo, kana avo vane hypertrophic cardiomyopathy, uko tsandanyama yemoyo yakakora zvisina kujairika.

Matambudziko eitsvo anokanganisa zvakanyanya maitiro emuviri wako anogadzirisa digoxin. Kana uine chirwere cheitsvo chakakomba, chiremba wako anogona kudzivisa digoxin zvachose kana kushandisa madosi akaderera zvakanyanya nekutarisa kwakanyanya, sezvo mushonga unogona kuwanda kusvika pamatanho ane njodzi.

Kusagadzikana kweElectrolyte, kunyanya mazinga akaderera epotassium kana magnesium, kunoita kuti digoxin toxicity ive yakanyanya. Chikwata chako chekurapa chichaongorora nekugadzirisa mazinga aya usati watanga kurapwa kwe digoxin.

Kuzvitakura kunoda kufunga kwakakosha, sezvo digoxin inogona kuyambuka placenta kuti isvike kumwana wako. Kunyange zvichidikanwa dzimwe nguva panguva yekuzvitakura, chiremba wako weobstetrician uye cardiologist vachashanda pamwechete kuyera mabhenefiti achipesana nenjodzi dzinogona kuitika.

Mazita eDigoxin Brand

Digoxin inowanikwa pasi pemazita akati wandei emhando, kunyangwe fomu re generic richishandiswa kazhinji muzvipatara nemakiriniki. Zita remhando rinozivikanwa zvakanyanya iLanoxin, iyo yanga iripo kwemakumi emakore uye inovimbwa nevapi vehutano pasi rese.

Mamwe mazita emhando anosanganisira Digitek naDigox, kunyangwe izvi zvisingawanzo shandiswa kune mafomu anojekeswa. Zvizhinji zvezvipatara zvehutano zvinoshandisa generic digoxin jekiseni nekuti rinoshanda zvakaenzana uye rinodhura zvakanyanya kupfuura shanduro dzemhando.

Kunyangwe iwe ukagamuchira zita remhando kana generic digoxin, mushonga unoshanda nenzira imwechete. Chinhu chinoshanda uye dosing zvakafanana, saka unogona kutarisira mabhenefiti akafanana uye mhedzisiro isina hanya nekuti ndeipi vhezheni yaunogamuchira.

Digoxin Alternatives

Mishonga yakawanda inogona kurapa kutadza kwemoyo uye atrial fibrillation kana digoxin isina kukodzera kana kushanda. Chiremba wemoyo wako achasarudza sarudzo yakanakisisa zvichienderana nemamiriro ako emoyo, mamwe matambudziko ehutano, uye kuti unotsungirira sei mishonga yakasiyana.

Pazvinhu zvine chekuita nekutadza kwemoyo, ACE inhibitors senge lisinopril kana beta-blockers senge metoprolol zvinowanzo sarudzwa semishonga yekutanga. Mishonga iyi yakaratidzwa kuti inovandudza huwandu hwekupona uye inowanzo kuve nyore kubata pane digoxin.

Mishonga mitsva yekutadza kwemoyo inosanganisira sacubitril/valsartan (Entresto) uye SGLT2 inhibitors senge dapagliflozin. Zvinodhaka izvi zvinopa mabhenefiti akanaka kune vanhu vazhinji vane kutadza kwemoyo uye zvinogona kushandiswa panzvimbo pe, kana pamwe chete ne, digoxin.

Kuti utarise atrial fibrillation, beta-blockers uye calcium channel blockers senge diltiazem zvinowanzo shandiswa. Mishonga iyi inowanzo kuve nyore kuyera uye kuongorora pane digoxin ichipa kudzora kwemoyo kunoshanda.

Mune zvimwe zviitiko, chiremba wako anogona kukurudzira maitiro senge cardioversion kana ablation panzvimbo yemishonga. Kurapa uku kunogona kudzorera rhythm yemoyo yakajairika pasina kudiwa kwemishonga yenguva refu.

Digoxin iri nani here pane Metoprolol?

Digoxin uye metoprolol zvinoshanda zvakasiyana uye hazvienzaniswi zvakananga, sezvo zvinowanzo shandiswa kune zvinangwa zvakasiyana kana kunyange pamwe chete. Sarudzo pakati pavo inoenderana nemamiriro ako emoyo, zvimwe zvinhu zvehutano, uye zvinangwa zvekurapa.

Pazvinhu zvine chekuita nekutadza kwemoyo, metoprolol inowanzo sarudzwa semushonga wekutanga nekuti yakaratidzwa kuti inobatsira vanhu kurarama kwenguva refu. Beta-blockers senge metoprolol inodzivirira moyo kubva kumahomoni ekushushikana uye inogona kunyatso kuvandudza basa remoyo nekufamba kwenguva.

Digoxin inowanzo wedzerwa kana metoprolol yoga isina kukwana kudzora zviratidzo kana kana usingakwanise kutora madosi akakwirira ebeta-blockers. Inobatsira zvikuru kune vanhu vanoramba vaine zviratidzo pasinei nekurapa kwakanyanya nemimwe mishonga.

Kudzora mwero weatrial fibrillation, mishonga yose miviri inogona kushanda, asi metoprolol inowanzo kuve nyore kubata nayo. Hairevi kuongororwa ropa kakawanda kunodiwa ne digoxin, zvichiita kuti ive nyore kushandisa kwenguva refu.

Vanhu vazhinji vanotora mishonga yose miviri pamwe chete, sezvo vachitsinhirana zvakanaka. Chiremba wemoyo wako achasarudza musanganiswa wakanakisa zvichienderana nezvido zvako uye kupindura kurapwa.

Mibvunzo Inowanzo Bvunzwa Nezve Digoxin

Digoxin Yakachengeteka Here Kune Vanhu vane Chirwere cheItsvo?

Digoxin inoda kufunga zvakanyanya kune vanhu vane chirwere cheitsvo nekuti itsvo dzako ndidzo dzine basa rekubvisa mushonga mumuviri wako. Kana basa reitsvo rakakanganiswa, digoxin inogona kuvaka kusvika pamatanho ane njodzi, ichiwedzera njodzi yehupfu.

Kana uine chirwere cheitsvo chinyoro kusvika pakati nepakati, chiremba wako achiri kukwanisa kunyora digoxin asi achashandisa madosi akaderera uye achatarisa mazinga eropa rako kakawanda. Vachatarisawo basa reitsvo rako nguva dzose kuti vaone kuti harisi kuipa.

Vanhu vane chirwere cheitsvo chakakomba kana avo vari pa dialysis vanoda kugadzirisa madosi akakosha. Nephrologist yako uye cardiologist vachashanda pamwe chete kuti vaone kana digoxin yakachengeteka kwauri uye kuti dose yakakodzera ingave yakadii.

Ndoita Sei Kana Ndikagamuchira Digoxin Yakawandisa Netsaona?

Digoxin overdose idambudziko guru rekurapa rinoda kurapwa kuchipatara nekukasira. Sezvo nyanzvi dzehutano dzichigara dzichipa majekiseni e digoxin, overdoses netsaona hazviwanzoitiki, asi dzinogona kuitika nekuda kwekukanganisa kwekushandisa kana kunzwisiswa kwemunhu.

Zviratidzo zvekuwandisa digoxin zvinosanganisira kusvotwa kwakanyanya, kurutsa, kuvhiringidzika, matambudziko ekuona, uye shanduko dzine njodzi dzemoyo. Kana ukaona chero zviratidzo izvi mushure mekutambira digoxin, zivisa chikwata chako chehutano nekukasira.

Kurapa kwekuwandisa digoxin kunogona kusanganisira mishonga yekurwisa mhedzisiro yayo, kutarisirwa kwezviratidzo, uye muzviitiko zvakanyanya, mushonga unozivikanwa se digoxin immune fab. Chikwata chekurapa chichatarisa rhythm yemoyo wako nguva dzose uye chichapa kurapwa kwakakodzera.

Ndingaita Sei Kana Ndikakanganwa Dose yeDigoxin?

Sezvo majekiseni e digoxin achipiwa nenyanzvi dzehutano munzvimbo dzekurapa, kukanganwa dose kazhinji hakusi chinhu chaunofanira kunetseka nacho. Chikwata chako chekurapa chichava nechokwadi chekuti unogamuchira mushonga wako sezvakanyorwa panguva yaunenge uri muchipatara kana kushanya kukiriniki.

Kana uri kuchinja ku digoxin yemuromo kumba uye ukakanganwa dose, tora nekukasira sezvaunorangarira, kunze kwekunge yava nguva yechikamu chako chinotevera. Usambofa wakatora zvikamu zviviri panguva imwe chete kuti ugadzirise dose yakakanganwa, sezvo izvi zvinogona kukonzera mhedzisiro ine njodzi.

Bata chiremba wako kana usina chokwadi chekuti chii chekuita nedose yakakanganwa. Vanogona kupa gwara rakatarwa zvichienderana nechirongwa chako chekushandisa uye mamiriro ako azvino.

Ndingamira Rini Kutora Digoxin?

Sarudzo yekumisa digoxin inoenderana nemamiriro ako emoyo ari pasi uye kuti uri kupindura sei kurapwa. Chiremba wako wemoyo achagara achiongorora kana uchiri kuda mushonga uye kana mabhenefiti achienderera mberi achipfuura chero njodzi.

Kune vamwe vanhu vane kukundikana kwemoyo, digoxin inogona kungodiwa panguva yezviitiko zvakanyanya kana nguva yekuvandudzwa kwezviratidzo. Kana mamiriro ako agadziriswa nekumwe kurapwa, chiremba wako anogona zvishoma nezvishoma kuderedza uye pakupedzisira kumisa digoxin.

Kana uine chronic atrial fibrillation, unogona kuda digoxin kwenguva refu. Zvisinei, chiremba wako achatarisa zvakare kurapwa kwako nguva nenguva uye anogona kukuchinjira kune mamwe mishonga kana kugadzirisa kurapwa kwako zvichienderana nekupindura kwako uye chero mhedzisiro.

Usambomira kutora digoxin kamwe kamwe usina kutarisirwa nachiremba, sezvo izvi zvinogona kukonzera kuti mwoyo wako uwedzere nekukurumidza. Chiremba wako achagadzira chirongwa chakachengeteka chekudzikisa kana kumisa kuri kwakakodzera.

Ndingatora Mamwe Mishonga Ndiri Kutambira Digoxin?

Mishonga yakawanda inogona kuita interaction ne digoxin, saka zvakakosha kuzivisa timu yako yehutano nezve mishonga yese, zvinowedzera, uye zvigadzirwa zvemiti zvauri kutora. Dzimwe interaction dzinogona kuwedzera digoxin mazinga kusvika pamwero unotyisa, nepo vamwe vachigona kuderedza kushanda kwayo.

Mishonga yakajairika inogona kuwedzera digoxin mazinga inosanganisira mamwe maantibiotics, antifungal drugs, uye mamwe mishonga yekudzikisa ropa. Chikwata chako chekurapa chichanyatsoongorora mishonga yako yese uye kugadzirisa zviyero sezvinodiwa kudzivirira interaction.

Mishonga inotengeswa pasina mushonga yakaita seantacids inogona kukanganisa digoxin absorption, saka nguva yekutora inova yakakosha. Vapi vehutano vako vachabatana nechirongwa chako chemishonga kuti vaderedze interaction vachive nechokwadi chekuti kurapwa kwako kwese kunoramba kuchishanda.