Chii chinonzi Durvalumab: Zvazvinoshandiswa, Mishonga, Mativi eMuviri uye Zvimwe

Durvalumab imhando yemushonga wekenza immunotherapy unobatsira masoja ako emuviri kurwisa mhando dzekenza dzakasiyana-siyana zvakanyanya. Inopiwa kuburikidza neIV (intravenous) infusion, zvinoreva kuti inoyerera zvakananga muropa rako kuburikidza netsinga muruoko rwako kana chipfuva.

Mushonga uyu ndewemukirasi wemishonga inonzi checkpoint inhibitors, iyo inoshanda nekubvisa "mabhureki" ayo masero ekenza anoisa pamuviri wako. Funga nezvazvo sekubatsira dziviriro dzemuviri wako dzemuviri kuziva nekurwisa masero ekenza akavanda kubva pakuonekwa.

Durvalumab Inoshandiswa Kunei?

Durvalumab inonyanya kushandiswa kurapa mhando dzekenza dzemapapu uye kenza yeguvhu. Chiremba wako anonyora mushonga uyu kana mamwe marapirwo asina kushanda kana kenza yapararira kune dzimwe nhengo dzemuviri wako.

Mamiriro makuru anorapwa ne durvalumab anosanganisira non-small cell lung cancer (NSCLC) isina kupararira zvakanyanya uye mhando dzekenza yeguvhu yepamusoro. Inowanzo shandiswa mushure mekunge wapedza radiation therapy kana kana kenza yakadzoka pasinei nemamwe marapirwo.

Kenza yemumapapu, durvalumab inowanzo piwa kana kenza iri muchikamu III, zvinoreva kuti yakanyanya asi haina kupararira kune dzimwe nhengo dzemuviri wako. Muzviitiko zvekenza yeguvhu, inowanzo chengeterwa matanho epamusoro kana kenza yapararira kupfuura guvhu pacharo.

Durvalumab Inoshanda Sei?

Durvalumab inoshanda nekudzivisa protein inonzi PD-L1 iyo masero ekenza anoshandisa kuvanza kubva kumasoja ako emuviri. Kana protein iyi yakavharwa, masero ako emuviri anogona kuziva nekurwisa kenza zviri nani.

Muviri wako une checkpoints yakavakirwa-mukati iyo inodzivirira kubva pakurwisa masero ane hutano. Masero ekenza anonyengerera anoshandisa ma checkpoints aya kuti azvidzivirire. Durvalumab inobvisa dziviriro iyi, ichibvumira masoja ako emuviri kuita basa rayo zvakanyanya.

Mushonga uyu unoonekwa sekurapa kwakanangana pane chemotherapy yechinyakare. Kazhinji inonyoro pamuviri wako kupfuura kurapwa kwekenza kwetsika, kunyangwe ichiri kukonzera mhedzisiro sezvo immune system yako inova inoshanda.

Ndingatora sei Durvalumab?

Durvalumab inopiwa seIV infusion muchipatara kana nzvimbo yekurapa kenza. Hauzogone kutora mushonga uyu kumba kana nemuromo - inofanirwa kupihwa nevashandi vehutano vakadzidziswa.

Infusion inowanzo tora maminitsi makumi matanhatu kuti apedze. Iwe uchagara zvakanaka pachigaro apo mushonga unoyerera kuburikidza neIV mutsara muropa rako. Vanhu vazhinji vanogamuchira kurapwa mumasvondo maviri kusvika ku4, zvichienderana nemamiriro avo chaiwo.

Pamberi peimwe neimwe infusion, timu yako yehutano ichatarisa zviratidzo zvako zvakakosha uye inogona kukupa mishonga yekudzivirira allergic reactions. Haufaniri kutsanya usati warapwa, uye unogona kudya zvakajairika pamazuva ekurapa. Kugara wakanyatsogadzirwa nemvura nekunwa mvura yakawanda kunobatsira.

Ndingatora Durvalumab kwenguva yakareba sei?

Kureba kwekurapwa kwe durvalumab kunosiyana zvakanyanya zvichienderana nerudzi rwako rwekenza uye kuti unopindura sei kumushonga. Vamwe vanhu vanogamuchira kurapwa kwemwedzi yakati wandei, nepo vamwe vachigona kuenderera mberi kwegore rinopfuura.

Kenza yemumapapu, kurapwa kunowanzoenderera kwemwedzi gumi nemiviri kana uchichigamuchira zvakanaka uye kenza yako isiri kufambira mberi. Kenza yeguvhu, kurapwa kunogona kuenderera mberi zvachose chero bedzi ichibatsira kudzora kenza yako uye isingakonzeri mhedzisiro yakakomba.

Chiremba wako achatarisa nguva dzose kufambira mberi kwako kuburikidza nekutarisa uye bvunzo dzeropa. Vachagadzirisa chirongwa chako chekurapa zvichienderana nekuti kenza yako inopindura sei uye kuti muviri wako unobatana sei nemushonga. Chinangwa ndechekuenderera mberi nekurapa chero bedzi ichikubatsira iwe usingakonzere mhedzisiro isingagamuchirwe.

Ndezvipi Zvakaipa zveDurvalumab?

Durvalumab inogona kukonzera matambudziko nekuti inoshandisa immune system yako, iyo dzimwe nguva inorwisa matishu ane hutano pamwe chete nemasero ekenza. Matambudziko mazhinji anogadzirisika, asi mamwe anogona kuva akakomba uye anoda kutariswa kwekurapa nekukurumidza.

Heano matambudziko anowanzoitika aunogona kusangana nawo panguva yekurapa:

• Kuneta uye kunzwa kuneta kupfuura zvakajairika
• Kukosora kana kufema kwemhepo
• Kutsvuka kweganda kana kukwenya
• Dhiria kana shanduko mukufamba kwematumbo
• Kuderera kwechido
• Kurwadziwa kwemhasuru kana majoini
• Nausea

Matambudziko aya anowanzoitika zvishoma nezvishoma uye anogona kugadziriswa nekuchengetedza uye mishonga. Chikwata chako chehutano chichashanda newe kuderedza kusagadzikana kupi zvako.

Nepo zvisingawanzoitiki, durvalumab inogona kukonzera matambudziko akakomba anoda kutariswa kwekurapa nekukurumidza. Izvi zvinoitika kana immune system yako yakashandiswa ichirwisa nhengo dzine hutano mumuviri wako.

Matambudziko akakomba anoda kutarisirwa nekukurumidza anosanganisira:

• Kuzvimba kwemapapu kwakanyanya (pneumonitis) kunokonzera kukosora kusingaperi kana matambudziko ekufema
• Matambudziko echiropa aine zviratidzo zvakaita seganda reyellowing, weti yakasviba, kana kurwadziwa kwakanyanya mudumbu
• Dhiria rakanyanya kana colitis neropa mumatope
• Matambudziko ethyroid anokonzera kuneta kwakanyanya, shanduko dzehuremu, kana kurova kwemoyo
• Matambudziko eitsvo aine kuderedzwa kweweti kana kuzvimba
• Ganda rakakomba rinoita nekuputika kwakapararira kana kuputika
• Matambudziko e adrenal gland anokonzera kuneta kwakanyanya, dzungu, kana kufenda

Chikwata chako chekurapa chinokutarisa zvakanyanya kune izvi zvirwere kuburikidza nekuongororwa kweropa nguva dzose uye bvunzo dzemuviri. Matambudziko mazhinji akakomba anogadziriswa nekukurumidza kurapwa, kazhinji kusanganisira mishonga inodzikamisa immune system yako.

Ndiani Asingafaniri Kutora Durvalumab?

Durvalumab haikodzerani nemunhu wese, uye chiremba wako achanyatsoongorora kana zvakachengeteka kwauri usati watanga kurapwa. Mamwe mamiriro ezvinhu ezvokurapa uye mamiriro anoita kuti mushonga uyu uve nengozi.

Haufaniri kupiwa durvalumab kana iwe uchiziva kuti une allergic reaction yakakomba kumushonga uyu kana zvikamu zvawo. Chiremba wako achavawo akanyatso chenjerera kana uine zvirwere zve autoimmune zvinoshanda uko immune system yako yatove kurwisa matishu ane hutano.

Mamiriro anoda kufungwa zvakakosha anosanganisira:

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• Zvirwere zve autoimmune zvinoshanda senge rheumatoid arthritis, lupus, kana inflammatory bowel disease
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• Nhoroondo yezvipingamupinyi zvakakomba zvine chekuita ne immune kubva kune mamwe immunotherapy zvinodhaka
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• Zvirwere zvinoshanda zvinorwiswa ne immune system yako
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• Vanogamuchira nhengo dzemuviri vachitora mishonga inodzvinyirira immune system
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• Kuzvitakura kana kuyamwisa
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• Chirwere chakakomba chechiropa kana itsvo
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Chiremba wako achayerera mabhenefiti anogona kuitika pamusoro penjodzi mumamiriro ako chaiwo. Dzimwe nguva durvalumab inogona kushandiswa nekuchenjerera uye matanho ekuwedzera, kunyangwe uine mamwe emamiriro aya.

Mazita eDurvalumab Brand

Durvalumab inotengeswa pasi pezita rekuti Imfinzi. Iri ndiro zita rimwe chete rinowanikwa remushonga uyu, sezvo richiri pasi pekudzivirirwa kwepatent nemugadziri wepakutanga.

Paunogamuchira kurapwa kwako, uchaona

Zvimwe zvinogona kushandiswa zvinosanganisira pembrolizumab (Keytruda), nivolumab (Opdivo), uye atezolizumab (Tecentriq). Mishonga iyi yese inoshanda nekudzivisa mapuroteni akasiyana echeckpoint, zvichibvumira immune system yako kurwisa kenza zvakanyanya.

Sarudzo pakati pemishonga iyi inoenderana nerudzi rwekenza yako, kurapwa kwakamboitwa, uye zvinhu zvehutano hwemunhu. Chiremba wako weoncologist achakurudzira sarudzo yakanakisa zvichienderana nekutsvagurudza kwazvino uye mamiriro ako ekurapa akasiyana.

Zvimwe zvinogona kushandiswa zvakaita sechemotherapy, radiation therapy, kana mishonga yekurapa inogonawo kutariswa zvichienderana nemaitiro ekenza yako uye nhanho.

Ko Durvalumab Ari Nani Kudarika Pembrolizumab?

Durvalumab na pembrolizumab vese vanodzivirira checkpoint vanoshanda, asi vanoshanda zvakanyanya kune marudzi akasiyana ekenza uye mamiriro. Hapana mushonga wakanyanya

Chiremba wako achatarisa hutano hwemoyo wako usati watanga kurapwa uye achakutarisa zvakanyanya panguva yekurapa. Kana uine nhoroondo yematambudziko emoyo, ungangoda bvunzo dzenguva dzose dzebasa remoyo uye kubatana kwepedyo pakati pechiremba wako weoncologist uye cardiologist.

Ndingaita Sei Kana Ndikakanganwa Kudya Durvalumab?

Kana ukakanganwa kudya durvalumab yakarongwa, taura nechikwata chako chehutano nekukasira kuti urongezve. Usaedze "kubata" nekugadzirisa zvikamu zviri pedyo - izvi zvinogona kuwedzera njodzi yako yemigumisiro.

Chiremba wako achasarudza nguva yakanakisa yekudya kwako kunotevera zvichienderana nekuti zvakatora nguva yakareba sei kubva pakurapwa kwako kwekupedzisira. Muzviitiko zvakawanda, iwe unongotangazve chirongwa chako chetsika kubva pazuva idzva rekugadzwa.

Ndingamira Rini Kutora Durvalumab?

Unofanirwa kungomira kurapwa kwe durvalumab mushure mekurukurirana zvakadzama nachiremba wako weoncologist. Sarudzo inoenderana nekuti kenza yako iri kupindura sei, migumisiro yaunowana, uye hutano hwako hwese.

Zvikonzero zvakajairika zvekumira zvinosanganisira kufambira mberi kwekenza pasinei nekurapwa, migumisiro yakakomba isingavandudzi nekugadzirisa, kana kupedzisa nguva yakarongwa yekurapa. Chiremba wako achashandisa scans uye bvunzo dzeropa kubatsira kuita sarudzo iyi yakakosha.

Ndingawana Majekiseni Ndiri Kutora Durvalumab Here?

Majekiseni mhenyu anofanirwa kudziviswa uchitora durvalumab nekuti immune system yako yakabatidzwa inogona kuita zvisingatarisirwi. Zvisinei, majekiseni asina basa (semushonga wefuru) anowanzo chengeteka uye anowanzo kurudzirwa kukudzivirira kubva kuzvirwere.

Nguva dzose zivisa vanopa hutano hwako kuti uri kugamuchira durvalumab usati watora majekiseni chero api zvayo. Vanogona kukupa zano pamusoro penguva yakanakisa uye majekiseni akakodzera mamiriro ako.

Durvalumab Ichakanganisa Kubereka Kwangu Here?

Durvalumab inogona kukanganisa kubereka muvarume nevakadzi, kunyangwe kukanganisa chaiko hakunzwisiswe zvizere. Kana uri kuronga kuva nevana, kurukura sarudzo dzekuchengetedza kubereka nachiremba wako usati watanga kurapwa.

Mishonga iyi inogona kukuvadza vana vari kukura, saka kudzivirira pamuviri kunoshanda kwakakosha panguva yekurapwa uye kwemwedzi yakati wandei mushure meiyo dose yako yekupedzisira. Chikwata chako chekuchengetedza hutano chichapa gwara rakajeka pamusoro pekuronga mhuri panguva yekurapwa kwako.