Eculizumab (inowaniswa muchipatara)

Bkemv, Epysqli, Soliris

Jekiseni yeEculizumab inoshandiswa kurapa rudzi rweronda reropa runonzi paroxysmal nocturnal hemoglobinuria (PNH). Mushonga uyu unobatsira kuderedza kuparadzwa kweropa tsvuku kana kuputsika (hemolysis) muvarwere vane PNH. Mushonga uyu unoshandiswawo kurapa chirwere chakakomba cheitsvo chinonzi atypical hemolytic uremic syndrome (aHUS). Jekiseni yeEculizumab inoshandiswawo kurapa chirwere chetsinga nemisungo chinonzi generalized myasthenia gravis (gMG) muvarwere vane anti-acetylcholine receptor (AchR) antibody positive. Jekiseni yeEculizumab inoshandiswawo kurapa neuromyelitis optica spectrum disorder (NMOSD), chirwere chisingawanzoitika chinokonzera kuzvimba kwetsinga dzemaziso nemuromo wemutsipa. Inoshandiswa muvarwere vane anti-aquaporin-4 (AQP4) antibody positive. Jekiseni yeEculizumab ndiyo monoclonal antibody inoshanda pane immune system. Mushonga uyu unowanikwa chete pasi pechirongwa chekugoverwa kwakaganhurwa chinonzi Ultomiris® neSoliris® REMS (Risk Evaluation and Mitigation Strategy) Program. Chigadzirwa ichi chinowanikwa mumafomu anotevera ekurapa:

Pakusarudza kushandisa mushonga, ngozi dzokutora mushonga unofanira kuyerwa nemabhenefiti awo. Iyi sarudzo iwe nesachiremba wenyu muchaita. Kune mushonga uyu, zvinotevera zvinofanira kufungwa: Udza chiremba wako kana wakambonzwa chero mhinduro isingawanzoitika kana chirwere cheallergy kumushonga uyu kana mimwe mishonga. Uyewo udza nyanzvi yako yehutano kana uine mamwe marudzi eallergies, akadai sekudya, dyes, preservatives, kana mhuka. Kune zvigadzirwa zvisinganyorwi, verenga zvinyorwa zvepakiti kana zvinhu zvakanyatsonaka. Zvidzidzo zvakakodzera zvakaitwa kusvika pari zvino hazvina kuratidza matambudziko chaiwo epediatric aizoita kuti kushandiswa kwekuzhambura kwe eculizumab kurapa atypical hemolytic uremic syndrome muvana kuve kwakaoma. Zvisinei, kuchengetedzwa uye kushanda kwekuzhambura kwe eculizumab kurapa mamwe mamiriro ezvinhu hazvina kusimbiswa muvana. Zvidzidzo zvakakodzera zvakaitwa kusvika pari zvino hazvina kuratidza matambudziko chaiwo egeriatric aizoita kuti kushandiswa kwekuzhambura kwe eculizumab kuve kwakaoma muvakuru. Hapana zvidzidzo zvakakwana muvakadzi zvekuona ngozi yemwana pakushandisa mushonga uyu panguva yekuyamwisa. Yera mabhenefiti anogona kuitika pamwe nengozi dzinogona kuitika usati watora mushonga uyu panguva yekuyamwisa. Kunyange zvazvo mimwe mishonga isingafaniri kushandiswa pamwe chete, mune dzimwe nguva mishonga miviri yakasiyana inogona kushandiswa pamwe chete kunyange kana kuwirirana kungangoitika. Munyaya idzi, chiremba wako angada kuchinja dose, kana kuti dzimwe nhau dzinogona kudiwa. Paunenge uchitora mushonga uyu, zvakakosha kuti nyanzvi yako yehutano izive kana uri kutora chero mishonga iri pazasi. Kuwirirana kunotevera kwakasarudzwa zvichienderana nekuwanda kwazvo uye hazvisi zvese zvinosanganisirwa. Kushandisa mushonga uyu nechero mishonga inotevera kazhinji hakuzombofungidzirwi, asi kunogona kudiwa mune dzimwe nguva. Kana mishonga yacho yose ikanyorwa pamwe chete, chiremba wako angachinja dose kana kuti ungashandisa sei imwe kana mishonga yacho yose. Mimwe mishonga haifaniri kushandiswa panguva yekudya kana pedyo nenguva yekudya kana kudya marudzi akati echikafu sezvo kuwirirana kungangoitika. Kushandisa doro kana fodya nemimwe mishonga kunogona zvakare kukonzera kuwirirana kuitika. Kurukurai nehutano hwako hwenyanzvi kushandiswa kwemushonga wako nechikafu, doro, kana fodya. Kuvapo kwemamwe matambudziko ehutano kunogona kukanganisa kushandiswa kwemushonga uyu. Ita shuwa kuti unoudza chiremba wako kana uine mamwe matambudziko ehutano, kunyanya: