Chii chinonzi Edrophonium Injection: Zvayinoshandiswa, Dosages, Migumisiro, nezvimwe

Edrophonium injection mushonga unovharidzira kwechinguvana kuparadzwa kwe acetylcholine, mutumwa wemakemikari mune yako tsinga. Izvi zvinogadzira kuvandudzwa kwenguva pfupi asi kunooneka musimba remhasuru uye kushanda. Vapi vehutano vanonyanya kushandisa mushonga uyu wejekiseni sechishandiso chekuongorora kubatsira kuziva mamiriro emhasuru netsinga, kunyanya myasthenia gravis.

Chii chinonzi Edrophonium?

Edrophonium mushonga unotora nguva pfupi, uyo uri muboka remishonga inonzi cholinesterase inhibitors. Inoshanda nekudzivirira kuparadzwa kwe acetylcholine, iyo yakakosha pakutaurirana pakati petsinga dzako nemhasuru. Kana mazinga e acetylcholine akawedzera kwechinguvana, mhasuru dzako dzinogona kuita zvakanyanya.

Mushonga uyu unouya semhinduro yakajeka, isina ruvara iyo vapi vehutano vanopa kuburikidza nejekiseni mutsinga yako. Kusiyana nemimwe mishonga yakawanda, edrophonium inoshanda nekukurumidza asi inongogara kwemaminitsi mashoma. Iyi nguva yakasarudzika inoita kuti ive inobatsira pakuyedzwa kwekuongorora pane kurapwa kuri kuenderera mberi.

Iwe unowanzo shandisa edrophonium muchipatara kana kiriniki, uko nyanzvi dzezvekurapa dzinogona kunyatso tarisa mhinduro yako. Mushonga uyu unozivikanwawo nezita rawo rebrand Tensilon, kunyangwe vhezheni yechinyakare ichishandiswa zvakanyanya nhasi.

Chii chinonzi Edrophonium chinoshandiswa?

Edrophonium inonyanya kushanda sechishandiso chekuongorora kubatsira vanachiremba kuziva myasthenia gravis, mamiriro apo immune system yako inorwisa hukama pakati petsinga nemhasuru. Munguva yekuyedzwa, chiremba wako achajekesa edrophonium uye achatarisa kuvandudzwa kwenguva pfupi musimba rekusava nesimba kana maziso akarembera.

Mushonga uyu unoshandiswawo kusiyanisa pakati pe myasthenic crisis uye cholinergic crisis muvarwere vakatowanikwa vaine myasthenia gravis. Myasthenic crisis inoitika kana mamiriro ako achiwedzera uye uchida mushonga wakawanda, nepo cholinergic crisis ichiitika kana wakagamuchira mushonga wakawandisa.

Dzimwe nguva, vanachiremba vanoshandisa edrophonium kudzosa mhedzisiro yemamwe ma relaxants emhasuru anoshandiswa panguva yekuvhiya. Izvi zvinobatsira kuona kuti mhasuru dzako dzadzoka kumabasa avo akajairika mushure memaitiro ekurapa. Zvisinei, kushandiswa uku hakusi kwakajairika sekushandiswa kwayo kwekuongorora.

Muzviitiko zvisingawanzoitiki, vanopa hutano vanogona kushandisa edrophonium kuyedza mamwe matambudziko e neuromuscular kana kuongorora kushanda kwemamwe marapirwo e myasthenia gravis. Kushandiswa uku kwakakosha kunoda kutarisirwa kwekurapa kwakanyatsojeka uye hunyanzvi.

Edrophonium Inoshanda Sei?

Edrophonium inoshanda nekudzivisa enzyme inonzi acetylcholinesterase, iyo inowanzoita kuti acetylcholine mumuviri wako iparadzwe. Kana enzyme iyi yakavharwa, acetylcholine inoungana pamusanganiswa pakati petsinga dzako nemhasuru, ichigadzira zviratidzo zvakasimba zvekukonana kwemhasuru.

Funga nezve acetylcholine sechinhu chakakosha chinovhura kufamba kwemhasuru. Mumamiriro ezvinhu akaita se myasthenia gravis, hapana zvakakwana zvekukiya zvinoshanda zvemakiyi aya. Edrophonium haigadziri zvimwe zvekukiya, asi inochengeta makiyi aripo kwenguva refu kuitira kuti ave nemikana yakawanda yekushanda.

Mushonga uyu unoonekwa sewakati simba asi unotora nguva pfupi. Mhedzisiro yayo inowanzo kutanga mukati memasekonzi makumi matatu kusvika makumi matanhatu ekujekesa uye inotora maminitsi mashanu kusvika gumi chete. Nguva pfupi iyi inoita kuti ive yakanaka pakuyedza asi isina kukodzera kurapwa kwenguva refu.

Kutanga nekukurumidza uye nguva pfupi zvinorevawo kuti chero mhedzisiro yaunowana ichave yenguva pfupi. Hunhu uhu hunoita kuti edrophonium ive yakachengeteka pakushandiswa kwekuongorora ichienzaniswa nemishonga inotora nguva refu mukirasi imwechete.

Ndinofanira Kutora Sei Edrophonium?

Haugoni kuzvipa edrophonium iwe pachako - inogara ichipiwa nevashandi vehutano munzvimbo yekurapa. Mushonga uyu unouya sejojo rinopinda zvakananga mutsinga yako yeropa kuburikidza neIV line kana dzimwe nguva mumhasuru yako. Chiremba wako achasarudza chiyero chaicho zvichienderana nehuremu hwako, zera, uye bvunzo chaiyo iri kuitwa.

Usati wapiwa edrophonium, haufanirwe kudzivisa chikafu kana chinwiwa kunze kwekunge chiremba wako akuraira zvakananga kuti uite saizvozvo. Zvisinei, unofanira kuzivisa timu yako yehutano nezve mishonga yese yaunotora, kusanganisira mishonga isingatengwi pamusoro pe-the-counter uye zvinowedzera.

Jojo racho pacharo rinotora masekonzi mashoma, asi iwe uchatariswa zvakanyanya kwemaminitsi akati wandei mushure meizvozvo. Chikwata chako chehutano chichatarisa shanduko musimba rako, kufema, uye mamiriro ako ese panguva ino.

Iwe unowanzo gamuchira edrophonium uchivata pasi kana kugara zvakanaka. Iyi nzvimbo inobatsira kuona kuchengeteka kwako uye inobvumira vanopa hutano kuti vanyatsoona chero shanduko mukushanda kwemhasuru yako.

Ndingatora Edrophonium Kwenguva Yakareba Sei?

Edrophonium haisi mushonga waunotora kwenguva yakareba. Yakagadzirirwa bvunzo imwe chete yekuziva, uye mhedzisiro yayo inopera zvakasikwa mukati me5 kusvika ku10 maminitsi. Hauzove nechinyorwa chekutora kumba kana chirongwa chekurapa chekutevera.

Kana uri kuita bvunzo dzakawanda, chiremba wako angangokupa edrophonium pazviitiko zvakasiyana, asi kushandiswa kwega kwega kuchiri kuratidzwa kumwe chete, kwenguva pfupi. Mushonga hauvaki mumuviri wako kana kuda kuwedzera zvishoma nezvishoma kana kuderedzwa mukuyera.

Kune varwere vane myasthenia gravis vanoda kurapwa kuri kuenderera mberi, vanachiremba vanowanzo nyora mishonga inoshanda kwenguva refu sepyridostigmine pane kudzokorora edrophonium majekiseni. Basa reEdrophonium rinoramba richinyanya kuongorora pane kurapa.

Ndezvipi Zvakaipa zveEdrophonium?

Vanhu vazhinji vanogona kushandisa edrophonium zvakanaka, asi semishonga yese, inogona kukonzera matambudziko. Mashoko akanaka ndewekuti chero matambudziko aunosangana nawo achava emunguva pfupi nekuda kwemishonga inoshanda kwenguva pfupi.

Heano matambudziko anowanzoitika aunogona kusangana nawo, uchifunga kuti izvi zvinowanzoenda mukati memaminitsi:

• Kunzwa kusvotwa kana kusagadzikana mudumbu
• Kuwedzera kuburitswa kwemate
• Kutukwa zvakanyanya kupfuura zvakajairika
• Kutinhira kwemhasuru kana fasciculations
• Kutambudzika mudumbu
• Manyoka
• Kuwedzera kuita weti
• Kunzwa dzungu kana kupera simba

Zviratidzo izvi zvinoitika nekuti edrophonium inowedzera acetylcholine mumuviri wako wese, kwete chete panzvimbo dzemitsipa-mhasuru dziri kuyedzwa. Vanhu vazhinji vanowana matambudziko aya achigoneka sezvo vachiziva kuti achapfuura nekukurumidza.

Kune zvakare mamwe matambudziko akakomba asi asingawanzoitiki anoda kutariswa kwekurapa nekukurumidza. Chikwata chako chehutano chichange chichitarisa izvi, asi zvinobatsira kuziva kuti chii:

• Kutambudzika kukuru kufema kana kutambudzika kwekufema
• Kurova kwemoyo kusina kujairika kana kurwadziwa muchipfuva
• Kushaya simba kwemhasuru kwakanyanya (mhinduro ye paradoxical)
• Kutapukirwa
• Kupera kuziva
• Maitiro akakomba ekuita allergic ane kuzvimba kana rash

Maitiro akakomba aya haawanzoitiki, uye iwe uchave uri munzvimbo yekurapa uko kurapwa nekukurumidza kunowanikwa kana zvichidikanwa. Vapi vako vehutano vakadzidziswa kuziva nekugadzirisa mamiriro aya nekukurumidza.

Ndiani Asingafaniri Kutora Edrophonium?

Vanhu vakati wandei havafaniri kugamuchira edrophonium nekuda kwekuwedzera njodzi yematambudziko akakomba. Chiremba wako achaongorora nhoroondo yako yekurapa zvakanyatsonaka asati asarudza kana mushonga uyu wakachengeteka kwauri.

Haufaniri kugamuchira edrophonium kana uine mamwe mamiriro emoyo, sezvo mushonga unogona kukanganisa rhythm yako yemoyo uye chiyero. Heano mamiriro makuru anoita kuti edrophonium isakodzere:

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• Matambudziko akakomba emoyo (arrhythmias)
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• Kurwisa kwemoyo kuchangobva kuitika kana chirwere chemoyo chisina kugadzikana
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• Asthma yakakomba kana chirwere chekufema chinogara (COPD)
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• Kuvharika kwematumbu kana weti
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• Kuziva allergy kune edrophonium kana mishonga yakafanana
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• Chirwere cheitsvo chakakomba
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• Chirwere che peptic ulcer chiri kushanda
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Chiremba wako achavawo nechokwadi pakushandisa edrophonium kana uri nepamuviri kana kuyamwisa, kunyangwe dzimwe nguva zvingave zvakakosha zvekuziva. Mushonga unogona kuyambuka placenta uye zvinogona kukanganisa mwana wako.

Kana uine nhoroondo yekubata, chikwata chako chehutano chichayera njodzi nemabhenefiti nekuchenjerera. Kunyangwe edrophonium inogona kukonzera kubata mune dzimwe nguva dzisingawanzoitiki, ruzivo rwekuziva rwayo runogona kukosha mukutarisirwa kwako.

Zera rega rega harikubvise pakugamuchira edrophonium, asi vanhu vakuru vanogona kunge vachinyanya kukanganiswa nemhedzisiro yayo. Chiremba wako achagadzirisa muyero zvinoenderana uye achakutarisa zvakanyanya panguva yekuedzwa.

Mazita eEdrophonium Brand

Edrophonium yakatanga kutengeswa pasi pezita remhando Tensilon naValeant Pharmaceuticals. Zvisinei, shanduro yezita remhando haichawanikwi zvakanyanya munyika dzakawanda, kusanganisira United States.

Nhasi, iwe unowanzoona edrophonium semushonga wegeneric. Shanduro dzeGeneric dzinoshanda nenzira imwechete nechigadzirwa chezita remhando uye dzinosangana nematanho akafanana ekuchengetedza uye kushanda. Mupi wako wehutano achangozvitaura se

Nepo edrophonium ichiripo chiyero chegoridhe chekuedzwa kwakawanda kwekuongorora, pane dzimwe nzira dzaungafunga nachiremba wako. Sarudzo inoenderana nekuti chii chirwere chiri kuongororwa uye mamiriro ako chaiwo ekurapa.

Kuti vaongorore myasthenia gravis, chiremba wako angashandisa dzimwe nzira panzvimbo pe, kana kuwedzera kune, bvunzo ye edrophonium. Bvunzo dzeropa dzinogona kuona ma antibodies chaiwo ane hukama ne myasthenia gravis, ichipa ruzivo rwekuongorora pasina kudiwa kwejekiseni.

Zvidzidzo zvekuendeswa kwetsinga uye electromyography (EMG) zvinogonawo kubatsira kuongorora zvirwere zve neuromuscular. Miedzo iyi inoyera mabasa emagetsi mutsinga dzako nemhasuru, ichipa ruzivo rwakadzama nezvekuti sisitimu yako yetsinga iri kushanda sei.

Kune varwere vasingakwanise kugamuchira edrophonium, vanachiremba vangashandisa bvunzo dzemapaketi echando kune zvimwe zviratidzo zvakaita semaziso anodonha. Kushandisa chando kunogona kuvandudza basa remhasuru kwechinguvana mu myasthenia gravis, ichipa zviratidzo zvekuongorora pasina mushonga.

Mune zvimwe zviitiko, chiremba wako angaraira kuyedzwa kwe oral pyridostigmine, mushonga unogara kwenguva refu mukirasi imwechete se edrophonium. Kana zviratidzo zvako zvikavandudzika zvakanyanya nemushonga uyu, zvinogona kutsigira kuongororwa kwe myasthenia gravis.

Ko Edrophonium Ari Nani Kudarika Pyridostigmine?

Edrophonium ne pyridostigmine vanoshanda zvinangwa zvakasiyana, saka kuenzanisa zvakananga hakusi kufanana nekuenzanisa maapuro nemaapuro. Edrophonium inoshanda zvakanaka sechishandiso chekuongorora nekuda kwekutanga kwayo nekukurumidza uye nguva pfupi, nepo pyridostigmine yakakodzera kurapwa kuri kuenderera mberi.

Pakuongorora, chiito chekukurumidza che edrophonium chinoita kuti chive chikuru kune pyridostigmine. Unogona kuona mhedzisiro mukati meminiti, uye kana uine mhedzisiro, dzinogadzirisa nekukurumidza. Pyridostigmine inotora maminitsi makumi matatu kusvika makumi matanhatu kuti ishande uye inogara kwemaawa akati wandei, zvichiita kuti isashande pakuyedza.

Asi, pakurapa myasthenia gravis kwenguva refu, pyridostigmine inoshanda zvakanyanya kupfuura edrophonium. Unogona kutora pyridostigmine nemuromo kakawanda pazuva kuti uchengetedze kutonga kwezviratidzo, nepo edrophonium yaizoda kuwana IV nguva dzose uye kuongororwa muchipatara.

Simba remishonga iyi rakaenzana, asi nguva yavo yekuita inovaita kuti vakodzere mamiriro akasiyana. Funga nezve edrophonium semufananidzo wekuongorora nekukurumidza, nepo pyridostigmine ichipa rubatsiro rwekuchengetedza.

Chiremba wako achasarudza mushonga wakakodzera zvichienderana nekuti unoda kuongororwa kana kurapwa kuri kuenderera mberi. Varwere vazhinji vanotanga kugamuchira edrophonium kuti vaedzwe uye ipapo, kana vaongororwa vane myasthenia gravis, vanochinjira ku pyridostigmine yekutarisira zuva nezuva.

Mibvunzo Inowanzo Bvunzwa Nezve Edrophonium

Edrophonium Yakachengeteka Here Kune Zvirwere Zvemoyo?

Edrophonium inogona kukanganisa kurova kwemoyo wako uye rhythm, saka inoda kufunga zvakanyanya kana uine chirwere chemoyo. Chiremba wako achaongorora mamiriro ako chaiwo emoyo uye anogona kusarudza kuti mabhenefiti ekuongorora anopfuura njodzi, kunyanya sezvo mhedzisiro yemushonga iri pfupi.

Kana uine chirwere chemoyo chinyoro, chakasimba, unogona kuramba uchikwanisa kugamuchira edrophonium nekutarisa pedyo. Zvisinei, kana uine matambudziko akakomba e rhythm yemoyo, kurwisa kwemoyo kwemazuva ano, kana chirwere chemoyo chisina kugadzikana, chiremba wako anogona kusarudza nzira dzimwe dzekuongorora.

Chikwata chako chehutano chichatarisa rhythm yemoyo wako nguva dzose panguva yekuedzwa kana uine chero matambudziko emoyo. Vachavawo nemishonga iripo yekurwisa mhedzisiro ye edrophonium kana zvichidikanwa, kunyangwe matambudziko akakomba emoyo asingawanzoitiki.

Ndoitei Kana Ndikagamuchira Edrophonium Yakawandisa Netsaona?

Kupfuura muyero we edrophonium idambudziko remishonga, asi iwe unogara uchigamuchira mushonga uyu munzvimbo yekuchengetedza hutano uko kurapwa nekukurumidza kunowanikwa. Chikwata chako chekurapa chichaziva zviratidzo zvekuwandisa nekukurumidza uye chichaita zvakakodzera.

Zviratidzo zve edrophonium yakawandisa zvinosanganisira kusimba kwemhasuru, kuoma kufema, kugadzirwa kwemate akawandisa, kusvotwa kwakanyanya nekutsvuka, uye shanduko dzinogona kuva nenjodzi mumoyo. Zviratidzo izvi zvinogona kukura nekukurumidza asi zvinorapika nekuchengetwa kwakakodzera kwekurapa.

Vapi vehutano vane mushonga unonzi atropine unogona kurwisa mhedzisiro ye edrophonium. Mushonga uyu unoshanda nekudzivisa chiitiko che acetylcholine chakawandisa chinokonzera zviratidzo zvekuwandisa. Chikwata chako chekurapa chakadzidziswa kuverenga muyero wakakodzera uye kuushandisa nekukurumidza kana zvichidiwa.

Mashoko akanaka ndewekuti edrophonium overdoses haawanzoitiki nekuti vapi vehutano vanoverenga madosi nekuchenjerera uye mushonga unotora nguva shoma. Kunyangwe iwe ukagamuchira zvakanyanya, mhedzisiro ichatanga kuparara zvakasikwa mukati memaminitsi.

Ndoita Sei Kana Edrophonium Test Isingashande?

Muedzo we edrophonium usina kunaka haurevi kuti hauna myasthenia gravis kana mamwe mamiriro emuviri. Dzimwe nguva bvunzo inoda kudzokororwa, kana chiremba wako angada kushandisa nzira dzakasiyana dzekuongorora kuti awane mhinduro yakajeka.

Zvikonzero zvakati wandei zvinogona kukanganisa mhedzisiro yebvunzo, kusanganisira nguva yezviratidzo zvako, mamwe mishonga yaunotora, uye mhasuru dziri kuyedzwa. Chiremba wako angakurudzira kudzokorora bvunzo panguva yakasiyana kana zviratidzo zvako zvakanyanya.

Kana bvunzo ye edrophonium ichiramba isina chokwadi, chiremba wako anozokumbira mamwe maedzo akadai sebasa reropa kuti aongorore myasthenia gravis antibodies, nerve conduction studies, kana imaging scans. Miedzo iyi inogona kupa rumwe ruzivo rwekubatsira kuita kuongororwa.

Dzimwe nguva, chiremba wako angakurudzira kuyedza kurapwa nemishonga inoshanda kwenguva refu yakaita se pyridostigmine. Kana zviratidzo zvako zvikavandudzika zvakanyanya nekutapwa, izvi zvinogona kutsigira kuongororwa kunyangwe bvunzo ye edrophonium yakanga isina kunaka.

Ndingadzokera Rinhi Kuzviitwa Zvangu Zvenguva Dzose Mushure meEdrophonium?

Unogona kazhinji kudzokera kuzviitwa zvenguva dzose nekukasika mushure mekuwana edrophonium, sezvo mhedzisiro yayo ichipera mukati memaminitsi mashanu kusvika gumi. Zvisinei, chiremba wako angakurudzira kumirira zvishoma kuti uve nechokwadi chekuti unonzwa zvakadzoka zvakakwana kune zvakajairika usati wabva kunzvimbo yekurapa.

Kana wakawana chero mhedzisiro yezvinhu panguva yebvunzo, mirira kusvikira izvi zvapera zvachose usati watyaira kana kushandisa michina. Vanhu vazhinji vanonzwa zvakanaka mukati memaminitsi gumi nemashanu kusvika makumi maviri vachigamuchira jekiseni, asi teerera muviri wako uye usakurumidze kana usiri kunzwa zvakanaka.

Hakuna zvirambidzo zvekudya kana zvirambidzo zvekuita mushure mebvunzo ye edrophonium. Unogona kudya, kunwa, uye kutora mishonga yako yenguva dzose sezvakajairika kunze kwekunge chiremba wako akupa mirairo yakatarwa.

Kana uri kuita mamwe maedzo kana maitiro pazuva rimwe chetero, zivisa timu yako yehutano kuti wakagamuchira edrophonium. Kunyangwe zvisingaiti kuti zvikanganise mamwe maedzo, zvakanaka nguva dzose kuchengeta timu yako yekurapa ichiziva zvizere nezve chero mishonga yawakagamuchira.

Ndingatora Mishonga Yangu Yenguva Dzose Mushure meEdrophonium?

Hongu, unogona kazhinji kutora mishonga yako yenguva dzose mushure mekuwana edrophonium. Mushonga haushandi nemishonga yakajairika, uye nguva yayo pfupi zvinoreva kuti haizove mumuviri wako kwenguva yakareba zvakakwana kukonzera hukama huri kuenderera mberi.

Kana iwe wakatotora mishonga ye myasthenia gravis, chiremba wako angangokupa mirairo yakatarwa nezve nguva. Dzimwe nguva, vachakukumbira kuti ubate mishonga iyi pamberi pebvunzo kuti uwane mhedzisiro yakarurama, wobva wadzokera kwairi mushure.

Nguva dzose zivisa timu yako yezvehutano pamusoro pemishonga yose yaunotora, kusanganisira mishonga inotengeswa pasina chiremba nemamwe mavitamini. Kunyange zvazvo kusangana kwemishonga iyi kuchiwanzika, timu yako yezvokurapa inoda ruzivo rwakakwana kuti ive nechokwadi chekuchengeteka kwako.

Kana uine mibvunzo pamusoro pemishonga chaiyo, bvunza mupi wako wehutano usati wabva kunzvimbo yekurapa. Vanogona kukupa zano rako pachako zvichienderana nenhoroondo yako yezvokurapa yakazara uye mishonga yaunotora parizvino.