Chii chinonzi Exemestane: Zvinoshandiswa, Mishonga, Migumisiro uye Zvimwe

Exemestane mushonga unopiwa nachiremba unobatsira kurapa mamwe marudzi ekenza yemazamu kuvakadzi vakapfuura menopause. Iyo ndeyeboka remishonga inonzi aromatase inhibitors, iyo inoshanda nekudzivisa kugadzirwa kwe estrogen mumuviri wako. Mushonga uyu unoita basa rakakosha mukudzivirira maseru ekenza kubva pakukura nekupararira kana estrogen ichikurudzira kukura kwavo.

Chii chinonzi Exemestane?

Exemestane mushonga wemuromo unouya muchimiro chepiritsi uye unotorwa nemuromo kamwe pazuva. Yakagadzirirwa zvakananga vakadzi vakapfuura menopause vane hormone receptor-positive breast cancer. Mushonga unoshanda nekudzivisa zvachose enzyme inonzi aromatase, iyo muviri wako unoshandisa kugadzira estrogen mushure mekuenda kumwedzi.

Mishonga iyi inoonekwa seyakatarwa therapy nekuti inonyanya kutarisana nenzira dzehormone dzinokurudzira mamwe marudzi ekenza yemazamu. Kusiyana nechemotherapy iyo inokanganisa maseru ese anokurumidza kukamukana, exemestane inotarisa pakuderedza mazinga e estrogen mumuviri wako wese. Chiremba wako anowanzo kupa mushonga uyu sechikamu chechirongwa chakazara chekurapa chinogona kusanganisira mamwe marapirwo.

Chii chinonzi Exemestane chinoshandiswa?

Exemestane inonyanya kushandiswa kurapa hormone receptor-positive breast cancer muvakadzi vakapfuura menopause. Chiremba wako anogona kuinyora mumamiriro akati wandei zvichienderana nerudzi rwekenza yako uye nhoroondo yekurapa.

Iko kushandiswa kwakajairika ndeye adjuvant therapy, zvinoreva kuti inopihwa mushure mekurapa kwekutanga senge kuvhiyiwa kana chemotherapy kuderedza njodzi yekuti kenza idzoke. Inogonawo kushandiswa seyekutanga-mutsara wekurapa kenza yemazamu yepamberi kana metastatic yakapararira kune dzimwe nhengo dzemuviri wako.

Nguva dzose vanachiremba vanonyora exemestane kuvakadzi vane gomarara rakafambira mberi kunyangwe vachirapwa nemumwe mushonga wemahomoni unonzi tamoxifen. Muzviitiko izvi, kuchinja kuenda kuexemestane kunogona kubatsira kudzora gomarara kana mushonga wekutanga usingachashandi. Chiremba wako weoncologist achasarudza nguva yakanakisa uye nzira yekuti iwe pachako uende nayo.

Exemestane Inoshanda Sei?

Exemestane inoshanda nekugara ichivharira enzyme ye aromatase, iyo ine basa rekushandura mamwe mahomoni kuita estrogen mumuviri wako. Iyi nzira yakakosha zvikuru mushure mekuenda kumwedzi apo mazai ako anomira kugadzira estrogen zvakananga.

Paunotora exemestane, inonamatira kune enzyme ye aromatase uye inoidzima zvachose. Izvi zvinoderedza zvakanyanya huwandu hwe estrogen inofamba mumuviri wako, izvo zvakakosha nekuti mazhinji gomarara remazamu rinovimba ne estrogen kuti rikure uye riwedzere. Nekucheka iyi homoni, mushonga unobatsira kunyima maseru egomarara zvavanoda kuti vararame.

Uyu mushonga unoonekwa seune simba kwazvo mukukwanisa kwayo kuderedza mazinga e estrogen. Zvidzidzo zvinoratidza kuti exemestane inogona kuderedza mazinga e estrogen neanosvika 85-95% muvakadzi vakapfuura kumwedzi. Mhedzisiro yacho inogara kwenguva refu nekuti enzyme blocking inogara, kunyangwe muviri wako uchizogadzira ma enzyme matsva e aromatase nekufamba kwenguva.

Ndinofanira Kutora Sei Exemestane?

Exemestane inofanira kutorwa kamwe chete pazuva mushure mekudya, zviri nani panguva imwe chete zuva rega rega. Kuitora nechikafu kunobatsira muviri wako kutora mushonga zvakanyanya uye kunogona kuderedza mukana wekugumbuka mudumbu.

Unogona kutora exemestane nechero chikafu, asi vanhu vazhinji vanoona zviri nyore kuitora mushure mekusarura kana kudya kwemanheru. Piritsi rinofanira kumedzwa rose nemvura uye harifaniri kupwanywa, kuputswa, kana kutsengwa. Kana uine dambudziko rekumedza mapiritsi, taura nachiremba wako nezve dzimwe nzira.

Zvakakosha kuisa tsika inoshanda kwauri sezvo kuenderana kunobatsira kuchengetedza mazinga akagadzikana emushonga mumuviri wako. Vamwe vanhu vanogadzira alarm yezuva nezuva kana kuchengeta bhodhoro ravo remushonga pedyo nebhurasho ravo remazino sechiyero. Usanetseka kana dzimwe nguva ukatora nechikafu chidiki panzvimbo pechikafu chakazara, chero uchidya chimwe chinhu.

Ndingatora Exemestane Kwenguva Yakareba Sei?

Nguva yakajairika yekurapa yeexemestane inosiyana zvichienderana nemamiriro ako chaiwo, asi vakadzi vazhinji vanoi tora kwemakore mashanu. Oncologist wako achasarudza urefu hwakakodzera hwekurapa zvichienderana nerudzi rwekenza yako, nhanho, uye mhinduro yekurapa.

Kune adjuvant therapy mushure mekurapa kwekutanga, zano rakajairika rinowanzoita makore mashanu e hormone therapy mune zvese. Izvi zvinogona kunge zviri makore mashanu eexemestane chete, kana zvingave musanganiswa kwaunotora tamoxifen kwemakore mashoma achiteverwa neexemestane. Vamwe vakadzi vanogona kubatsirwa nekurapa kwakawedzerwa kupfuura makore mashanu.

Chiremba wako achatarisa nguva dzose mhinduro yako yekurapa uye anogona kugadzirisa nguva zvichienderana nekuti uri kutsungirira sei mushonga uye maitiro ekenza yako. Usambomira kutora exemestane usina kukurukura nazvo nechikwata chako chehutano kutanga, kunyangwe uchinzwa zvakanaka kana uchiona mhedzisiro.

Ndezvipi Zvinhu Zvinokonzerwa neExemestane?

Semishonga yese, exemestane inogona kukonzera mhedzisiro, kunyangwe kwete munhu wese anoona izvozvo. Zvizhinji zvemhedzisiro zvine chekuita nemhedzisiro yemushonga yekudzikisa mazinga e estrogen mumuviri wako.

Mhedzisiro yakajairika iyo vakadzi vazhinji vanoona inosanganisira hot flashes, kurwadziwa kwemajoini uye kuoma, kuneta, uye kurwadziwa nemusoro. Zviratidzo izvi zvinowanzoitika uye zvinogona kuvandudzika sezvo muviri wako uchigadzirisa kumushonga mumwedzi mishoma yekutanga yekurapa.

Heano mhedzisiro yaungasangana nayo, yakarongwa kubva kune yakajairika kusvika kune isingawanzoitiki:

• Kupisa kwemuviri uye kutukutira usiku
• Kurwadziwa mumajoini, kuoma, kana kurwadziwa kwemhasuru
• Kuneta uye kushaya simba
• Kutemwa nemusoro
• Nyonganyonga mudumbu kana kusvotwa
• Kutadza kurara
• Kuchinja kwemanzwiro kana kuora mwoyo
• Kutukutira zvakanyanya
• Dizziness
• Kushaya chido chekudya

Zvisingawanzoitiki asi zvakanyanya kukomba mhedzisiro inogona kusanganisira kuonda kwemapfupa (osteoporosis), kuwedzera njodzi yekutyoka, uye mhedzisiro yemoyo nemitsipa yeropa. Vamwe vakadzi vanogona kusangana nekuonda kwebvudzi, shanduko dzeganda, kana kuwedzera kwecholesterol. Mhedzisiro iyi inokura zvishoma nezvishoma uye inoda kutariswa nechikwata chako chehutano.

Zvisingawanzoitiki asi zvakanyanya kukomba mhedzisiro zvinosanganisira maitiro akakomba ekurwara, matambudziko echiropa, kana shanduko dzakakosha mumawoko eropa. Bata chiremba wako nekukurumidza kana ukaona kurwadziwa kwakanyanya mudumbu, kuita yero yeganda kana maziso, kuputika kana kubuda ropa zvisina kujairika, kana zviratidzo zvechirwere senge fivha inoramba iripo.

Ndiani Asingafaniri Kutora Exemestane?

Exemestane haina kukodzera munhu wese, uye mamiriro ezvinhu kana mamiriro ezvinhu anoita kuti isakodzere kana kuve nenjodzi. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa usati anyora mushonga uyu.

Vakadzi vasati vasvika kumwedzi havafaniri kutora exemestane nekuti inoshanda chete mushure mekuenda kumwedzi apo kugadzirwa kweestrogen kwachinjira kunzvimbo dzemuviri. Vakadzi vane pamuviri kana kuyamwisa havafaniri kutora mushonga uyu nekuti unogona kukuvadza mwana ari kukura.

Vanhu vane chirwere chechiropa chakakomba vangangotadza kugadzirisa exemestane zvakachengeteka, uye avo vane matambudziko akati wandei ematsvo vangangoda kugadzirisa muyero. Kana uine nhoroondo yeosteoporosis yakakomba kana kutyoka kakawanda, chiremba wako achada kuyera zvakanakira nekukuvadza zvakanyatso.

Munofanira kuzivisa chiremba wenyu kana muine nhoroondo yezvinhu zvinokonzera ropa, chirwere chemoyo, cholesterol yakakwira, kana kuora mwoyo. Kunyange zvazvo mamiriro aya asingadzivisi kushandiswa kweexemestane, anoda kutariswa zvakanyanya uye pamwe kurapwa kwakawedzerwa kuti zvidzore njodzi.

Mazita eExemestane Brand

Exemestane inowanikwa pasi pemazita akawanda emhando, Aromasin ndiyo inonyanya kuzivikanwa. Mushonga uyu wemhando ndiyo yaive yekutanga yakagadzirwa uye ichiri kunyorerwa zvakanyanya nevanoongorora gomarara.

Mhando dzisiri dzechokwadi dzeexemestane dziripowo uye dzine chinhu chimwe chete chinoshanda semhando yezita. Mishonga iyi isiri yechokwadi inopfuura bvunzo dzakanyanya kuti ive nechokwadi chekuti inoshanda zvakanyanya seAromasin. Inishuwarenzi yenyu inogona kusarudza vhezheni isiri yechokwadi, iyo inogona kubatsira kuderedza mari yenyu.

Mungave muchiwana zita remhando Aromasin kana exemestane isiri yechokwadi, kushanda kwemushonga uye kuchengeteka kwakafanana. Murapi wemishonga wenyu anogona kupindura mibvunzo pamusoro peiyo vhezheni yauri kuwana uye kukubatsira kunzwisisa chero misiyano mukuonekwa pakati pevagadziri.

Zvimwe Zvingashandiswa Panzvimbo peExemestane

Mishonga yakati wandei inogona kushanda seimwe nzira yeexemestane, zvichienderana nemamiriro ako ezvinhu. Kusarudza pakati pekurapa kwakasiyana-siyana kwehomoni kunoenderana nezvinhu zvakaita senhoroondo yako yekurapa, kushivirira kwemigumisiro, uye maitiro egomarara.

Zvimwe zvinodzivirira aromatase zvinosanganisira anastrozole (Arimidex) uye letrozole (Femara), iyo inoshanda zvakafanana neexemestane asi ine zvishoma zvakasiyana side effect profiles. Vamwe vakadzi vanoshivirira imwe aromatase inhibitor zvirinani pane imwe, saka kuchinja pakati pavo dzimwe nguva kunobatsira.

Tamoxifen inomirira kirasi yakasiyana yehomoni therapy inoshanda nekudzivisa estrogen receptors panzvimbo yekuderedza estrogen production. Mushonga uyu unogona kuva sarudzo kana usingakwanise kutsungirira aromatase inhibitors kana chiremba wako akasarudza kuti yakakodzera mamiriro ako.

Mishonga mitsva yakaita sefulvestrant (Faslodex) kana CDK4/6 inhibitors yakabatanidzwa nehomoni therapy inogona kufungwa mumamiriro ezvinhu akasiyana, kunyanya kenza yemazamu yakakura. Oncologist wako achabatsira kuona kuti ndeipi nzira inopa chiyero chakanakisa chekubudirira uye kutsungirirwa kwako.

Ko Exemestane Zviri Nani Kupfuura Anastrozole?

Zvese zviri zviviri exemestane uye anastrozole zvinoshanda aromatase inhibitors, asi zvinoshanda zvishoma zvakasiyana uye zvinogona kuva nezvimwe zvinokonzeresa. Exemestane inonzi

Exemestane inogona kushandiswa kuvakadzi vane chirwere chemoyo, asi zvinoda kutariswa zvakanaka uye kubatana nachiremba wako wemoyo. Mushonga uyu unogona kukanganisa mazinga echolesterol uye unogona kuva nemimwe migumisiro yemoyo nekuda kwekudziviswa kweestrogen.

Chiremba wako anogona kutarisa hutano hwemoyo wako zvakanyanya paunenge uchitora exemestane, kusanganisira bvunzo dzeropa dzenguva dzose dzekutarisa cholesterol nezvimwe zvinhu zvinokonzera njodzi yemoyo. Vamwe vakadzi vangada mamwe mishonga yekugadzirisa izvi, senge statins yekudzora cholesterol.

Sarudzo yekushandisa exemestane ine chirwere chemoyo inoenderana nekuyananisa mabhenefiti ekurapa kenza nekukanganisa kwemoyo. Chiremba wako weoncologist uye cardiologist vachashanda pamwechete kugadzira chirongwa chekutarisa chinochengeta kenza yako uye hutano hwemoyo wako mukutarisa.

Ndingaita Sei Kana Ndakashandisa Exemestane Yakawandisa Netsaona?

Kana ukatora zvakawanda kupfuura chiyero chako cheexemestane, taura nachiremba wako kana nzvimbo yekudzora muchetura nekukasira. Usamirira kuti uone kana zviratidzo zvichikura, sezvo kuwana zano rekurapa nekukurumidza nguva dzose ndiyo nzira yakachengeteka.

Kutora exemestane yakawandisa kunogona kukonzera migumisiro yakakomba senge kuneta zvakanyanya, kusvotwa zvakanyanya, kana zvimwe zviratidzo zvine chekuita nemazinga akaderera eestrogen. Nyanzvi dzezvekurapa dzinogona kukupa zano rekuti chii chekutarisa uye kana uchida kutariswa kwekurapa nekukurumidza.

Uya nebhodhoro remushonga newe kana uchida kutsvaga kutarisirwa kwekurapa, sezvo izvi zvichibatsira vanopa hutano kunzwisisa chaizvo zvawakatora uye zvakawanda sei. Usaedze "kudzivisa" chiyero chakawedzerwa nekusvetuka chiyero chako chinotevera chakarongeka kunze kwekunge wakanzi zvakananga nenyanzvi yehutano.

Ndingaita Sei Kana Ndikakanganwa Chiyero cheExemestane?

Kana ukakanganwa chiyero cheexemestane, tora nekukasira paunorangarira, chero zvisiri pedyo nenguva yechiyero chako chinotevera chakarongeka. Usawedzere nekutora zviyero zviviri panguva imwe chete kuti ugadzirise imwe yakarasika.

Kana nguva yekutora mushonga wako unotevera yaswedera (mukati memaawa gumi nemaviri), siya mushonga wawakakanganwa wotevera purogiramu yako yenguva dzose. Kutora mishonga miviri iri pedyo pedyo kunogona kuwedzera njodzi yako yemigumisiro isingadiwi pasina kuwedzera kubatsira.

Edza kuisa tsika dzinokubatsira kuyeuka mushonga wako wezuva nezuva, sekugadzira maalarm pafoni kana kushandisa varongi vemishonga. Kana uchikanganwa mishonga kazhinji, kurukura nzira nechikwata chako chekuchengetwa kwehutano kuti uvandudze kuenderana, sezvo kutora mishonga nguva dzose zuva nezuva kwakakosha pakurapa kenza zvakanaka.

Ndingamira Rini Kutora Exemestane?

Unofanira kungomira kutora exemestane kana chiremba wako weoncologist aona kuti zvakakodzera, kunyangwe uchinzwa zvakanaka kana uchisangana nemigumisiro isingadiwi. Sarudzo yekumisa kurapwa inoenderana nezvinhu zvakawanda zvinosanganisira rudzi rwekenza yako, mhinduro yekurapa, uye hutano hwako hwese.

Vakadzi vazhinji vanotora exemestane kwemakore anenge mashanu, asi vamwe vangada kurapwa kwenguva refu kana vangakwanisa kumira nekukurumidza zvichienderana nemamiriro avo ega. Chiremba wako achagara achiongorora kana kuenderera mberi nekurapwa kuchipa kubatsira kukuru kupfuura njodzi.

Kana migumisiro isingadiwi iri kuita kuti zvive zvakaoma kuenderera mberi nekurapwa, kurukura izvi nechikwata chako chekuchengetwa kwehutano pane kumira wega. Kazhinji, pane nzira dzekugadzirisa migumisiro isingadiwi kana kugadzirisa kurapwa kunokutendera kuti uenderere mberi uchigamuchira mabhenefiti ekurwisa kenza emushonga.

Ndingatora Exemestane Nemimwe Mishonga Here?

Exemestane inogona kuita zvakashata nemimwe mishonga, saka zvakakosha kuti uudze chiremba wako nezve mishonga yese yakanyorwa, mishonga isingatengwi, uye zvinowedzerwa zvauri kutora. Mimwe mishonga inogona kukanganisa mashandiro anoita exemestane kana kuwedzera njodzi yemigumisiro isingadiwi.

Mishonga ine estrogen yakaita se hormone replacement therapy kana mapiritsi ekudzivirira pamuviri anogona kupesana nemhedzisiro ye exemestane uye anofanira kudziviswa kazhinji. Zvimwe zvinowedzera zvemishonga yemakwenzi, kunyanya izvo zvine mhedzisiro yakaita se estrogen, zvinogonawo kukanganisa kurapwa.

Chiremba wako nemu pharmacist vanogona kukubatsira kunzwisisa mishonga ipi yakachengeteka kutora ne exemestane uye iyo yekudzivisa. Nguva dzose tarisa usati watanga chero mishonga mitsva kana zvinowedzera, kunyangwe izvo zvinoita sezvisina hukama nekurapwa kwako kenza.