Chii chinonzi Factor XIII (Nzira yeIntravenous): Zvinoshandiswa, Mishonga, Migumisiro uye Zvimwe

Factor XIII mushonga wekubatsira ropa kuita magwamba unopiwa kuburikidza neIV kubatsira ropa rako kuita magwamba akasimba, akagadzikana kana muviri wako usingakwanise kuita akakwana ega. Kurapa uku kunoponesa hupenyu kunotsiva protein inoshaya inoshanda seglue yebhayoloji, ichibatsira maronda kupora zvakanaka uye kudzivirira zviitiko zvinotyisa zvekubuda ropa.

Kana iwe kana mumwe munhu waunoda achida Factor XIII, ungangove uri kubata nechirwere chisingawanzoitiki asi chakakomba. Mashoko akanaka ndewekuti mushonga uyu wakabatsira vanhu vasingaverengeke kurarama hupenyu hune hutano, hwakachengeteka nekupa ropa ravo simba rekugwamba rinodiwa.

Chii chinonzi Factor XIII?

Factor XIII iprotein inogwamba iyo chiropa chako chinowanzoita kubatsira kugadzirisa magwamba eropa. Funga nezvayo sematanho ekupedzisira muhurongwa hwekubatsira muviri wako - inobatanidza uye inosimbisa magwamba kuitira kuti asaite kana uchiada zvakanyanya.

Paunozvarwa uine Factor XIII kushomeka, muviri wako hauiti zvakakwana zveprotein iyi kana kuita vhezheni isingashande zvakanaka. Pasina izvozvo, kunyange kucheka kudiki kunogona kutungamira kubuda ropa kwenguva refu, uye kubuda ropa kwemukati kunogona kuva kunotyisa upenyu.

Fomu reintravenous reFactor XIII rinogadzirwa kubva muropa revanhu rakapiwa iro rakanyatsoitwa uye rakaedzwa kuchengeteka. Mushonga uyu wakanyanya kupa ropa rako chinhu chinogwamba chiri kushaikwa, ichibatsira kudzorera basa rakajairika rekugwamba ropa.

Factor XIII Inoshandiswa Kunei?

Factor XIII inorapa congenital Factor XIII kushomeka, chirwere chisingawanzoitiki chekubuda ropa chinokanganisa vanhu vashoma vanopfuura 1 mu2 miriyoni pasi rose. Mamiriro aya anogona kukonzera zviitiko zvakakomba, zvisingatarisirwi zvekubuda ropa zvisingapinduri kurapwa kwakajairika.

Vanhu vane kushomeka uku vanowanzoona maitiro ekubuda ropa asinganzwisisike ayo anogona kuvhiringidza vanachiremba pakutanga. Unogona kuva nekubuda ropa kwakajairika mushure mekucheka kudiki asi wozotarisana nekubuda ropa kwemukati kunotyisa kana kupora kwemavanga kusina kunaka kunoita sekusina kukodzera kukuvadzwa.

Mishonga iyi inoshandiswawo kudzivirira pamberi pekuvhiyiwa kana maitiro emazino muvanhu vane kuzivikanwa kweFactor XIII kushomeka. Chiremba wako anogona kuikurudzira kana uri nepamuviri uye uine mamiriro aya, sezvo inogona kubatsira kudzivirira matambudziko ekubuda ropa panguva yekuzvara.

Factor XIII Inoshanda Sei?

Factor XIII inoshanda nekupedzisa maitiro ako ekugwamba ropa, ichiita sebhioni rinokosha. Paunokuvadzwa, muviri wako unogadzira clot yekutanga, asi Factor XIII inosimbisa uye inogadza clot iyoyo kuitira kuti isaputsike nekukurumidza.

Izvi zvinoonekwa semushonga wakanyanya kunyanya pane une simba kana usina simba mupfungwa dzechinyakare. Kushanda kwayo kunoenderana zvachose nekuti une kushomeka kwakatarwa kwaakagadzirirwa kurapa - haizobatsiri nemamwe marudzi ekusagadzikana kwekubuda ropa.

Kana yaiswa mumuviri wako, Factor XIII inotanga kushanda nekukurumidza nehurongwa hwako hwekugwamba. Mhedzisiro inogona kugara mavhiki akati wandei, ndosaka iwe usingawanzoita kurapwa kwemazuva ese semamwe mishonga.

Ndinofanira Kutora Sei Factor XIII?

Factor XIII inogara ichipiwa se infusion ye intravenous muchipatara kana nzvimbo yekurapa yakakosha nevashandi vehutano vakadzidziswa. Hauzokwanisi kutora mushonga uyu kumba kana nemuromo - inofanira kupiwa zvakananga mumuviri wako kuti ushande nemazvo.

Pamberi pe infusion yako, timu yako yehutano inogona kutarisa zviratidzo zvako zvakakosha uye kuongorora nhoroondo yako yekurapa kuti uone chero shanduko. Infusion chaiyo inowanzo tora maminitsi gumi nemashanu, uye iwe uchatariswa panguva yese yekuita chero maitiro.

Hapana chikonzero chekutsanya usati wapiwa mushonga, asi zvinobatsira kudya chikafu chakareruka usati wapiwa mushonga kuti usazonzwa dzungu kana kusurukirwa panguva yekupinza mushonga. Kugara uine mvura yakawanda nekunwa mvura yakawanda mumaawa mashoma usati wapiwa mushonga kunogona kukubatsira kuti unzwe wakasununguka.

Vanhu vazhinji vanogona kudzokera kuzviitiko zvavo zvenguva dzose munguva pfupi mushure mekuiswa kwemushonga, kunyangwe chiremba wako angakurudzira kudzivisa kurovedza muviri kwakasimba kwezuva rese. Chikwata chako chekuchengeta hutano chichapa mirairo chaiyo zvichienderana nemamiriro ako ega.

Ndingatora Factor XIII kwenguva yakareba sei?

Factor XIII inowanzoita mushonga wehupenyu hwese kune vanhu vane congenital Factor XIII kushomeka, asi kakawanda kunosiyana zvakanyanya zvichienderana nezvido zvako. Vamwe vanhu vanoda kupinzwa mushonga mumasvondo 4-6 ega ega, nepo vamwe vangatora mwedzi yakati wandei pakati pemishonga.

Chiremba wako achagadzira chirongwa chakagadzirirwa iwe zvichienderana nekukurumidza kwemuviri wako unoshandisa Factor XIII uye nhoroondo yako yekubuda ropa. Kana uine zviitiko zvichangoburwa zvekubuda ropa, unogona kuda mishonga inowanzoitika pakutanga kusvikira mazinga ako agadziriswa.

Chinangwa ndechekuchengetedza Factor XIII yakakwana mumuviri wako kudzivirira kubuda ropa kwega pasina mishonga isina basa. Chikwata chako chekuchengeta hutano chichatarisa mazinga eropa rako nguva dzose uye kuchinja chirongwa chako sezvinodiwa muhupenyu hwako hwese.

Ndezvipi Zvipingamupinyi zveFactor XIII?

Vanhu vazhinji vanotsungirira Factor XIII zvakanaka, asi semushonga chero upi zvake wakagadzirwa kubva kuplasma yemunhu, unogona kukonzera mhedzisiro kune vamwe vanhu. Zvinhu zvakajairika zvinowanzoita zvinyoro uye zvinoitika panguva kana munguva pfupi mushure mekuiswa kwemushonga.

Heano mhedzisiro yaungasangana nayo, uchifunga kuti maitiro akakomba haawanzoitika nemaitiro emazuva ano:

Mhedzisiro yakajairika inosanganisira:

• Musoro mudiki kana dzungu panguva yekurapa
• Nyonganyonga diki kana kunzwa kusagadzikana
• Kurwadziwa kwenguva pfupi kana kutsvuka panzvimbo yekujowa
• Kunzwa kuneta kana kusava nesimba kwemaawa mashoma mushure mekurapa
• Kurwadziwa kwemhasuru kudiki kwakafanana nezviratidzo zvakaita sefuruwenza

Izvi zvinowanzoenda zvega mukati memaawa mashoma uye hazvidi kumisa kurapa.

Zvisingawanzoitiki asi zvakanyanya kukomba mhedzisiro inogona kusanganisira:

• Maitiro ekuita allergic ane hives, kukwenya, kana kuoma kufema
• Kuumbwa kweropa kusingaite mumidziyo uko kusingafaniri kuitika
• Musoro unotyisa kana shanduko mukuona
• Kurwadziwa muchipfuva kana kufema
• Zviratidzo zveutachiona senge fivha kana kuneta kusingaperi

Kunyange zvazvo zvisingawanzoitiki, izvi zvinoda kutarisirwa kwekurapa nekukurumidza. Chikwata chako chehutano chinokutarisa zvakanyanya panguva yekurapa kunyanya kubata nekugadzirisa chero maitiro anokunetsa nekukurumidza.

Ndiani Asingafaniri Kutora Factor XIII?

Factor XIII haina kukodzera munhu wese, uye chiremba wako achanyatsoongorora kana yakachengeteka kwauri zvichienderana nenhoroondo yako yekurapa uye mamiriro ako ehutano azvino. Sarudzo iyi inosanganisira kuyera mabhenefiti achipesana nenjodzi dzinogona kuitika mumamiriro ako chaiwo.

Haufaniri kugamuchira Factor XIII kana uine maitiro akakomba ekuita allergic kune zvigadzirwa zveplasma zvevanhu kana chero zvikamu zvekurapa. Vanhu vane zvimwe zvirwere zve immune system vanogonawo kuda mamwe marapirwo.

Chiremba wako achanyatso chenjerera kana uine nhoroondo yegwamba reropa, chirwere chemoyo, kana sitiroko, sezvo Factor XIII inogona kuwedzera njodzi dzekuumbwa kweropa kune vamwe vanhu. Zvisinei, izvi hazvikubvise iwe kubva mukurapa - zvinongoreva kuti iwe uchada kutariswa zvakanyanya.

Vakadzi vane pamuviri nevanooyamwisa vanogona kugamuchira Factor XIII kana zvichidikanwa nemishonga, asi chiremba wako achakurukura njodzi dzakakosha nemabhenefiti newe. Mushonga uyu unowanzoonekwa sewakachengeteka kupfuura njodzi dzekubuda ropa risina kurapwa panguva yekuzvitakura.

Mazita eBrand eFactor XIII

Factor XIII inowanikwa pasi pemazita akati wandei ebrand, neCorifact ichiva iyo inonyanya kushandiswa muUnited States. Iri brand rine Factor XIII concentrate rinobva muplasma yevanhu uye rakaongororwa zvakanyanya kuchengeteka uye kushanda.

Mamwe mabhurandi epasi rose anosanganisira Fibrogammin P, iyo inoshandiswa munyika dzakasiyana siyana pasi rose. Zvese zvigadzirwa zveFactor XIII zvakabvumidzwa zvinopfuura kuyedzwa kwakanyanya uye maitiro ekuchenesa kubvisa zvinogona kusvibisa uku uchichengetedza kushanda kwemushonga.

Mupi wako wehutano achasarudza iyo yakanyanya kukodzera brand zvichienderana nekuwanikwa, nhoroondo yako yekurapa, uye ruzivo rwavo nezvigadzirwa zvakasiyana. Zvese zviratidzo zvakabvumidzwa zvinoshanda zvakafanana, kunyangwe vamwe vanhu vachigona kupindura zvishoma zviri nani kune imwe formulation kupfuura imwe.

Factor XIII Zvimwe Zvinhu

Parizvino, hapana dzimwe nzira dzechokwadi dzeFactor XIII yekurapa congenital Factor XIII kushomeka. Iyi protein yakanyanya kunyanya kuti mamwe mishonga yekubuda ropa haigone kutsiva basa rayo rakasiyana mukugadzirisa ropa.

Kune vanhu vasingakwanise kugamuchira plasma-derived Factor XIII nekuda kweallergies kana zvimwe zvikonzero, vanachiremba vanogona kushandisa kurapwa kunotsigira senge fresh frozen plasma, kunyangwe izvi zvisingashande zvakanyanya uye zvinotakura njodzi dzakakwirisa. Vamwe varwere vanogona kubatsirwa nemishonga yeantifibrinolytic iyo inobatsira kudzivirira clot breakdown.

Vatsvagiri vari kushanda pamhando dze recombinant (dzakagadzirwa murabhoritari) dzeFactor XIII dzaisazoda plasma yevanhu, asi izvi zvichiri mukuvandudzwa. Parizvino, plasma-derived Factor XIII inoramba iri iyo goridhe standard kurapwa kweichi chiitiko chisingawanzoitiki.

Ko Factor XIII Zviri Nani Kudarika Mamwe Mishonga Yekuita Kuti Ropa Riumbane?

Factor XIII haisi yakanaka zvachose kudarika mamwe mishonga yekuita kuti ropa riumbane - yakagadzirirwa zvakananga chimwe chinangwa chakasiyana zvachose. Nepo mishonga yakaita seFactor VIII ichirapa hemophilia A, Factor XIII inogadzirisa kushomeka kwakasiyana uko zvimwe zvinhu zvekugadzira ropa hazvigone kugadzirisa.

Kufananidza Factor XIII nemamwe marapirwo ekuita kuti ropa riumbane kwakafanana nekufananidza kiyi chaiyo kune rimwe kuki. Factor XIII inoshanda zvinoshamisa pakushandiswa kwayo kwakatarwa asi haizobatsiri nezvimwe zvirwere zvekubuda ropa, sezvo mamwe mishonga yekuita kuti ropa riumbane isingabatsiri nekushomeka kweFactor XIII.

Mukana weFactor XIII ndewekuti unogara kwenguva refu - kurapwa kumwe chete kunogona kupa dziviriro kwemavhiki kana mwedzi, kusiyana nemamwe ma clotting factors anoda kuiswa kazhinji. Izvi zvinoita kuti zvive nyore pakuchengetedza kwenguva refu kwehutano hwako.

Mibvunzo Inowanzo Bvunzwa Nezve Factor XIII

Q1. Factor XIII yakachengeteka here kune vanhu vane chirwere chechiropa?

Factor XIII inogona kushandiswa nekuchenjerera kune vanhu vane chirwere chechiropa, asi inoda kunyatso tariswa sezvo chiropa chinowanzoita ichi clotting factor. Chiremba wako achada kuenzanisa mabhenefiti ekurapa pamwe nenjodzi dzinogona kuitika zvichienderana nekuti chiropa chako chiri kushanda sei.

Vanhu vane matambudziko echiropa akapfava vanowanzo shingirira Factor XIII zvakanaka, asi avo vane chirwere chechiropa chakakomba vangangoda kugadziriswa dosi kana kuongororwa kakawanda. Chikwata chako chehutano chichashanda nenyanzvi dzechiropa kana zvichidikanwa kuti uve nechokwadi chekurapa kwakachengeteka.

Q2. Ndingaita sei kana ndikawana Factor XIII yakawandisa netsaona?

Kupfuurisa kweFactor XIII netsaona hakusi kwakajairika zvakanyanya sezvo ichigara ichipiwa nenyanzvi dzehutano munzvimbo dzakadzorwa. Kana iwe uchinetseka nezvekuwana zvakawandisa, taura nemupi wako wehutano nekukasira kana kuenda kukamuri yekukurumidzira.

Zviratidzo zvekuwandisa mushonga zvinogona kusanganisira zviratidzo zvisingawanzoitiki zvakadai semarwadzo akanyanya mumusoro, kurwadziwa muchipfuva, kana kuoma kufema. Zvisinei, Factor XIII ine chengetedzo yakakura, uye mhedzisiro yakakomba yekuwandisa mushonga haisi yakajairika kana ichipiwa nevashandi vehutano vakadzidziswa.

Q3. Ndingaita sei kana ndikakanganwa dose yeFactor XIII yakarongwa?

Kana ukakanganwa infusion yeFactor XIII yakarongwa, taura nachiremba wako nekukurumidza sezvinobvira kuti urongezve. Usamirira kusvika panguva yako inotevera yakajairika, kunyanya kana uri kusangana nekubuda ropa kana kupwanya zvisingawanzoitiki.

Chiremba wako anogona kukurudzira kutarisa pedyo kana zvirambidzo zvenguva pfupi zvezviitiko kusvikira wagamuchira dose yako yakarasika. Nguva yekurapa kwako kunotevera ichaenderana nekuti zvakatora nguva yakareba sei kubva pakuisa kwako kwekupedzisira uye zviratidzo zvako zvazvino.

Q4. Ndingamira rini kutora Factor XIII?

Vanhu vane congenital Factor XIII kushomeka vanowanzoita kurapwa kweupenyu hwese, sezvo iyi iri mamiriro ejeni asingavandudzi ega. Hauzofaniri kumisa Factor XIII usina kukurukura zvakadzama nachiremba wako.

Chiremba wako anogona kugadzirisa chirongwa chako chekurapa zvichienderana nekuchinja kwehupenyu hwako, zera, kana mararamiro, asi kumisa kurapwa zvachose kazhinji hakukurudzirwi. Kunyangwe usina kuve nezviitiko zvekubuda ropa nguva pfupi yadarika, kuchengetedza mazinga akakwana eFactor XIII kunobatsira kudzivirira matambudziko emunguva yemberi.

Q5. Ndingafamba here ndichitora Factor XIII?

Hongu, unogona kufamba uchigamuchira kurapwa kweFactor XIII, asi zvinoda kuronga pachine nguva uye kubatana nechikwata chako chehutano. Chiremba wako anogona kukubatsira kuronga kurapwa pazvipatara zvakakosha kwauri kuenda kana uchizove uri kure panguva ye infusion yakarongwa.

Kwemafambiro mapfupi, chiremba wako anogona kugadzirisa chirongwa chako chekurapa kuti ave nechokwadi chekuti wakafukidzwa panguva yako yese yekufamba. Nguva dzose takura zvinyorwa nezve mamiriro ako uye kurapwa kana iwe uchida rubatsiro rwekurapa rwekukurumidzira uri kure nemba.