Chii chinonzi Gemfibrozil: Zvazvinoshandiswa, Dosage, Side Effects uye Zvimwe

Gemfibrozil mushonga unopiwa nachiremba unobatsira kuderedza mafuta akawanda (triglycerides) muropa rako. Iwo wechikwata chemishonga inonzi fibrates, iyo inoshanda nekuderedza huwandu hwe triglycerides chiropa chako chinogadzira ukuwo ichibatsira kusimudzira mazinga ako akanaka echolesterol.

Chiremba wako angangokupa gemfibrozil kana kudya uye kurovedza muviri chete zvisina kukwana kuunza cholesterol yako uye triglyceride mazinga mumutinhimira une hutano. Mushonga uyu unobatsira zvikuru kune vanhu vane mazinga akakwirira e triglyceride, sezvo inogona kuderedza zvakanyanya njodzi ye pancreatitis, mamiriro akakomba anogona kuitika kana triglycerides ikawedzera zvakanyanya.

Chii chinonzi Gemfibrozil chinoshandiswa?

Gemfibrozil inonyanya kupihwa kurapa mazinga akakwirira e triglyceride muropa rako, kunyanya kana akakwira zvakanyanya (pamusoro pe500 mg/dL). Mushonga uyu unobatsira zvikuru pakuderedza triglycerides, iyo imhando yemafuta ayo muviri wako unochengetera simba asi anogona kukonzera matambudziko kana mazinga akakwira zvakanyanya.

Chiremba wako angangokupawo gemfibrozil kubatsira kudzivirira chirwere chemoyo kune vanhu vane mazinga akaderera echolesterol yakanaka (HDL) yakasanganiswa ne triglycerides yakakwirira. Kunyange zvazvo isiri sarudzo yekutanga yekuderedza cholesterol yakaipa (LDL), inogona kupa imwe rubatsiro munzvimbo iyi zvakare.

Mune zvimwe zviitiko, gemfibrozil inogona kushandiswa kurapa mamiriro asingawanzoitiki emagenetic anonzi familial hyperlipidemia, uko muviri wako unogadzira mafuta akawanda muropa. Mamiriro aya anomhanya mumhuri uye anowanzo kudiwa mushonga kuti utariswe zvinobudirira.

Gemfibrozil inoshanda sei?

Gemfibrozil inoshanda nekunangana nechiropa chako, uko mazhinji e triglycerides emuviri wako anogadzirwa. Inoshandisa zvikuru zvinogamuchira zvinonzi PPAR-alpha receptors, izvo zvinoudza chiropa chako kuti chigadzire triglycerides shoma uye kuparadza mafuta akawanda ari muropa rako.

Mushonga uyu unoonekwa seune simba zvishoma kana zvasvika pakudzikisa triglycerides, kazhinji achidzikisa ne20-50% muvanhu vazhinji. Unonyanya kushanda pakudzikisa mazinga epamusoro etriglyceride, zvichiita kuti ive chishandiso chinokosha chekudzivirira matambudziko akakomba akadai sepancreatitis.

Panguva imwecheteyo, gemfibrozil inobatsira kuwedzera mazinga ako akanaka echolesterol (HDL) neanenge 10-15%. Chiito ichi kaviri chinoita kuti chibatsire zvikuru vanhu vane musanganiswa wetriglycerides yakakwira uye cholesterol yakanaka yakaderera, maitiro anowedzera zvakanyanya njodzi yezvirwere zvemtima.

Ndingatora sei Gemfibrozil?

Tora gemfibrozil sezvinorairwa nachiremba wako, kazhinji kaviri pazuva maminitsi makumi matatu usati watora chikafu chamangwanani nemadekwana. Kuitora usati watora chikafu kunobatsira muviri wako kutora mushonga wacho zvakanaka uye kunoderedza mukana wekuti dumbu rigumbuke.

Unogona kutora gemfibrozil nemvura, uye haufaniri kudzivisa chero chikafu chako paunenge uchichitora. Zvisinei, zvakakosha kuchengetedza kudya kunovaka mwoyo kwakaderera mumafuta akazara uye shuga dzakareruka kuti uwane mhedzisiro yakanaka kubva mukurapa kwako.

Edza kutora zvikamu zvako panguva imwechete zuva rega rega kuti zvikubatsire kuyeuka uye kuchengeta mazinga akagadzikana emushonga mumuviri wako. Kana uri kutora mamwe mishonga, kunyanya zvinoderedza ropa kana ma statins, ita shuwa kuti chiremba wako anoziva nezvemishonga yako yese kuti udzivise kusangana kunogona kuva nengozi.

Usapwanye, kutsenga, kana kuputsa mahwendefa kunze kwekunge chiremba wako akakuudza zvakananga kuti uite kudaro. Vamedze vese negirazi remvura izere kuti uve nechokwadi chekunyudzwa kwakakodzera.

Ndingatora Gemfibrozil kwenguva yakareba sei?

Vanhu vazhinji vanoda kutora gemfibrozil kwemwedzi yakati wandei kuti vaone mabhenefiti akazara, nekuti kuvandudzwa kukuru mumazinga etriglyceride kazhinji kunooneka mukati mevhiki 2-4 yekutanga kurapwa. Chiremba wako achatarisa mazinga ako eropa nguva dzose kuti aone kuti mushonga uri kushanda sei.

Kune vanhu vazhinji, gemfibrozil inova mushonga wenguva refu nekuti triglycerides yakakwira inowanzo dzoka kana mushonga wamiswa. Chiremba wako achashanda newe kuti aone kana uchida kuramba uchiutora zvichienderana nemazinga ako e triglyceride, hutano hwako hwese, uye njodzi dzezvirwere zve mwoyo.

Vamwe vanhu vanogona kumisa kutora gemfibrozil kana vakakwanisa kuwana uye kuchengetedza mazinga ane hutano e triglyceride kuburikidza nekuchinja kukuru kwehupenyu, kusanganisira kurasikirwa uremu, kudya kwakavandudzwa, uye kurovedza muviri nguva dzose. Zvisinei, chisarudzo ichi chinofanira kugara chichiitwa nekuraira kwechiremba wako.

Kana uine mamiriro ejeneti anokonzera triglycerides yakakwira, ungangoda kutora gemfibrozil kwenguva isingagumi kuti uchengetedze mazinga ako ari munzvimbo yakachengeteka.

Ndezvipi Zvipingamupinyi zveGemfibrozil?

Semishonga yese, gemfibrozil inogona kukonzera mhedzisiro, kunyangwe vanhu vazhinji vachizvitsungirira zvakanaka. Mhedzisiro yakajairika inowanzoita nyoro uye inowanzoita nani sezvo muviri wako uchigadzirisa kumushonga.

Heano mhedzisiro yaungasangana nayo, kutanga neayo akajairika:

• Kusagadzikana mudumbu, kusvotwa, kana kurwadziwa mudumbu
• Dhayareya kana zvigaro zvakasununguka
• Dizziness kana kurwadziwa nemusoro
• Kurwadziwa kwemhasuru kana kurwadziwa mumajoini
• Kuneta kana kunzwa kuneta
• Meno eruswa kana kukwenya

Izvi zvinowanzoitika zvinowanzoita nyoro uye zvinowanzoita nani mukati memavhiki mashoma ekutanga kurapwa. Kana vachiramba kana kuva dambudziko, taura nachiremba wako nezve nzira dzekuzvigadzirisa.

Nepo zvisingawanzoitiki, kune zvimwe zvinokuvadza zvakanyanya zvinoda kutariswa kwekurapa nekukurumidza:

• Kurwadziwa kwakanyanya kwemhasuru, kusimba, kana kunzwira tsitsi (zviratidzo zvekuparara kwemhasuru)
• Weti yerima kana kuderedzwa kweweti
• Kurwadziwa kwakanyanya mudumbu kunogona kuratidza matambudziko e gallbladder
• Kusvava kweganda kana maziso (jaundice)
• Kubuda ropa kusinganzwisisike kana kupwanya
• Fivha inoramba iripo kana zviratidzo zvakaita sefuru

Kana uine chero matambudziko aya akakomba, fonera chiremba wako nekukasika kana kutsvaga rubatsiro rwekurapa rwekukurumidza.

Ndiani Asingafaniri Kutora Gemfibrozil?

Gemfibrozil haina kuchengeteka kumunhu wese, uye chiremba wako achanyatso funga nezve nhoroondo yako yekurapa asati akuraira. Vamwe vanhu vanofanira kudzivisa mushonga uyu zvachose nekuda kwenjodzi dzakawedzerwa dzezvirwere zvakakomba.

Haufaniri kutora gemfibrozil kana uine chirwere chakakomba cheitsvo, chirwere chechiropa chiri kushanda, kana chirwere chegallbladder. Mushonga uyu unogona kuwedzera mamiriro aya uye unogona kukonzera matambudziko ane njodzi muvanhu vane matambudziko ehutano aya.

Vanhu vari kutora mamwe mishonga vanofanirawo kudzivisa gemfibrozil nekuda kwekuita kwemishonga kunotyisa. Izvi zvinosanganisira mamwe mishonga ye statin (senge simvastatin), mamwe ma blood thinners, uye mamwe mishonga yechirwere cheshuga.

Kana iwe une pamuviri kana kuyamwisa, gemfibrozil ingasava sarudzo yakakunakira. Kunyange zvazvo paine data shoma pamusoro pekuchengeteka kwayo panguva yekuzvitakura, chiremba wako anowanzo kuraira dzimwe nzira dzekugadzirisa triglycerides yakakwira panguva ino.

Vanhu vane nhoroondo yezvirwere zvemuviri kana avo vakaita zvisina kunaka kune mamwe mishonga ye fibrate vanofanira kushandisa gemfibrozil nekuchenjerera kukuru, kana zvachose.

Mazita eGemfibrozil Brand

Zita rinowanzozivikanwa re gemfibrozil ndiLopid, iyo yaive zita rekutanga remhando apo mushonga uyu wakatanga kuunzwa. Unogonawo kuona ichirairwa pasi pezita re generic gemfibrozil, iro rinowanzo shoma mari asi rinoshanda nenzira imwechete.

Ose ari maviri mazita emhando uye generic ane chinhu chimwe chete chinoshanda uye anoshanda zvakaenzana. Mushonga wako unogona kutsiva imwe kune imwe kunze kwekunge chiremba wako achinyatsokumbira vhezheni yezita remhando.

Zvimwe zvirongwa zveinishuwarenzi zvinogona kuva nezvavanofarira kune zita remhando kana vhezheni ye generic, saka zvakakosha kutarisa nemupi wako weinishuwarenzi nezve sarudzo dzekuvhara.

Zvimwe Zvinhu zveGemfibrozil

Kana gemfibrozil isina kukukodzera, pane mamwe mishonga akati wandei anogona kubatsira kuderedza triglycerides uye kuvandudza cholesterol yako. Chiremba wako angangofunga nezveimwe nzira idzi zvichienderana nezvido zvako zvakakosha uye mamiriro ehutano.

Fenofibrate imwe mushonga wefibrate unoshanda zvakafanana ne gemfibrozil asi unogona kuve wakachengeteka kushandisa nemimwe mishonga, kunyanya mamwe ma statins. Inowanzoita imwe nzira yakanaka yevanhu vanoda zvese kuderedza triglyceride uye statin therapy.

Kune vanhu vane triglycerides yakanyanya kukwirisa, mishonga ye omega-3 fatty acid yakaita se icosapent ethyl (Vascepa) inogona kushanda zvakanyanya. Aya ndiwo akanyanya kuwanda, akacheneswa mafuta ehove anogadzirwa ayo akanyanya simba kupfuura zvinowedzera mafuta ehove.

Niacin (nicotinic acid) imwe sarudzo inogona kuderedza triglycerides uye kukwidza cholesterol yakanaka, kunyangwe ichiwanzokonzera flushing uye inogona kunge isina kukodzera munhu wese. Chiremba wako angangofungawo nezve mishonga mitsva yakaita sePCSK9 inhibitors mune dzimwe nguva.

Ko Gemfibrozil iri nani pane Fenofibrate?

Zvese gemfibrozil uye fenofibrate mishonga inoshanda ye fibrate, asi imwe neimwe ine zvakanakira zvayo zvichienderana nemamiriro ako chaiwo. Hapana imwe yakajairika "iri nani" pane imwe - sarudzo inoenderana nezvido zvako zveutano uye mamwe mishonga yaunotora.

Gemfibrozil inowanzoita zvishoma zvishoma pakukwidza cholesterol yakanaka (HDL) mazinga, izvo zvinoita kuti zvive zvakanyanya kubatsira kune vanhu vane HDL cholesterol yakaderera. Yakadzidzwawo kwenguva refu uye ine tsvagiridzo yakawanda inotsigira kushandiswa kwayo mukudzivirira chirwere chemoyo.

Fenofibrate, kune rumwe rutivi, inogona kuve yakachengeteka kushandisa nemishonga ye statin uye ine mashoma ekudyidzana kwemishonga zvachose. Inowanzo farirwa kana iwe uchida zvese kuderedza triglyceride uye statin therapy, kana kana iwe uchitora mishonga yakawanda.

Chiremba wako achafunga nezvezvinhu zvakaita semishonga yako mimwe, kushanda kwematsvo, uye maitiro ako chaiwo echolesterol paanosarudza kuti ndeipi fibrate iri nani kwauri. Mishonga yese iri miviri inoshanda pakudzikisa triglycerides, saka sarudzo "iri nani" ndiyo inoshanda zvakanyanya nehurongwa hwako hwekurapa.

Mibvunzo Inowanzo Bvunzwa Nezve Gemfibrozil

Q1. Gemfibrozil Yakachengeteka Kune Vanhu vane Chirwere cheShuga here?

Gemfibrozil inogona kuva yakachengeteka kune vanhu vane chirwere cheshuga, asi inoda kunyatso tariswa nekufunga nezve mimwe mishonga yako yeshuga. Mushonga uyu unogona kubatsira kuvandudza zvimwe zvezvinhu zvekurapa chirwere cheshuga nekudzikisa triglycerides, izvo zvinowanzo kuwedzera muvanhu vane chirwere cheshuga.

Zvisinei, gemfibrozil inogona kushamwaridzana nemimwe mishonga yeshuga, kunyanya mamwe emishonga yekare ye sulfonylurea, zvichikonzera kuti mazinga eshuga yeropa adzikire zvakanyanya. Chiremba wako achada kutarisa mazinga eshuga yeropa rako zvakanyatsonaka uye anogona kuda kugadzirisa mishonga yako yeshuga.

Kana uine chirwere cheshuga, ita shuwa kuti unoudza chiremba wako nezve mishonga yako yese yeshuga usati watanga gemfibrozil, uye ramba uchitarisa mazinga eshuga yeropa rako zvakanyanya panguva yekurapa.

Q2. Ndingaita Sei Kana Ndikatora Gemfibrozil Yakawandisa Netsaona?

Kana netsaona ukatora gemfibrozil yakawanda kupfuura yakarairwa, usavhunduke, asi zviitore zvakanyanya. Bata chiremba wako kana nzvimbo yekudzora muchetura nekukasira, kunyanya kana wakatora zvakawanda zvakanyanya kupfuura muyero wako wenguva dzose.

Zviratidzo zvegemfibrozil overdose zvinogona kusanganisira kurwadziwa kwakanyanya mudumbu, kusvotwa, kurutsa, manyoka, kurwadziwa kwemhasuru, kana dzungu. Kana ukaona chero zviratidzo izvi mushure mekutora mushonga wakawandisa, tsvaga rubatsiro rwekurapa nekukasira.

Kuti uzive mune ramangwana, funga kushandisa chirongwa chemapiritsi kana kumisa zviyeuchidzo zvefoni kuti zvikubatsire kuyeuka kana wakambotora muyero wako wezuva nezuva. Izvi zvinogona kubatsira kudzivirira kupeta kaviri netsaona.

Mubvunzo 3. Ndingaita Sei Kana Ndakakanganwa Dose yeGemfibrozil?

Kana ukakanganwa dose ye gemfibrozil, itore paunorangarira, asi chete kana zvapfuura maawa mashoma kubva panguva yako yakatarwa. Kana yava nguva yekutora dose yako inotevera, siya dose yakakanganwa uye uenderere mberi nechirongwa chako chemazuva ese.

Usambofa wakatora madosi maviri panguva imwe chete kuti ugadzirise dose yakakanganwa, sezvo izvi zvinogona kuwedzera njodzi yako yemigumisiro. Zviri nani kukanganwa dose imwe chete pane kuisa njodzi yekutora mushonga wakawandisa.

Kana uchikanganwa madosi kazhinji, taura nachiremba wako nezve nzira dzekukubatsira kurangarira, sekutora mushonga wako panguva imwe chete nebasa rako remazuva ese kana kushandisa chirongwa chekuyeuchidza mushonga.

Mubvunzo 4. Ndingamira Rini Kutora Gemfibrozil?

Unofanira kungomira kutora gemfibrozil pasi pekutungamirirwa nachiremba wako, kunyangwe uchinzwa zvakanaka kana mazinga ako etriglyceride akavandudzwa. Kumisa mushonga kamwe kamwe kunogona kukonzera kuti mazinga ako etriglyceride akwirezve, zvichikwanisa kukuisa panjodzi yematambudziko.

Chiremba wako achatarisa mazinga ako eropa nguva dzose uye anogona kufunga kuderedza dose yako kana kumisa mushonga kana ma triglycerides ako achiramba achidzora zvakanaka uye wakaita shanduko huru muhupenyu hwako. Sarudzo iyi ichavimba nezvinhu zvako zvekuzvimiririra uye hutano hwako hwese.

Kana uri kusangana nemigumisiro kana uchida kukurukura kumisa mushonga, rongera musangano nachiremba wako kuti uongorore sarudzo dzako. Vanogona kugadzirisa dose yako kana kukuchinjira kumushonga wakasiyana pane kumisa kurapwa zvachose.

Mubvunzo 5. Ndinganwe Doro Ndichitora Gemfibrozil?

Zvakanaka kuderedza kunwa doro uchitora gemfibrozil, sezvo doro rinogona kukwidza zvakanyanya mazinga etriglyceride uye kushanda kurwisa mabhenefiti emushonga. Kunyangwe kunwa zvine mwero kunogona kukanganisa zvinangwa zvako zvekurapa.

Doro rinogonawo kuwedzera njodzi yematambudziko echiropa kana rakasanganiswa negemfibrozil, kunyangwe izvi zvisingawanzoitika. Kana ukasarudza kunwa dzimwe nguva, chengeta zvishoma uye kurukura kunwa kwako doro nachiremba wako.

Kuti uwane mhedzisiro yakanaka kubva mukurapa kwako gemfibrozil, funga kuderedza kana kubvisa kunwa doro zvachose. Kuchinja uku kwehupenyu, pamwe chete nemushonga wako, kuchakupa mukana wakanaka wekuwana nekuchengetedza mazinga ane hutano etriglyceride.