Created at:1/13/2025
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Ibuprofen lysine imhando yakakosha yeibuprofen iyo vanachiremba vanopa kuburikidza neIV (intravenous) mutsetse zvakananga muropa rako. Mushonga uyu wakagadzirirwa zvakananga vacheche vachangozvarwa vane chirwere chemoyo chinonzi patent ductus arteriosus, uko mudzi weropa pedyo nemoyo hauvhariki zvakanaka mushure mekuberekwa.
Kusiyana nemapiritsi eibuprofen kana mvura yaungatora kumba kurwadziwa kana fivha, iyi vhezheni yeIV inoshanda nekukurumidza uye zvakanyatsonaka. Inoshandiswa chete munzvimbo dzekuchipatara pasi pekutariswa kwechiremba, ichipa vanachiremba kutonga kuri nani pamusoro pemushonga wakawanda mwana wako anogamuchira.
Ibuprofen lysine ine chinangwa chimwe chete: kubatsira kuvhara patent ductus arteriosus (PDA) muvacheche vasati vazvarwa. Iyo PDA mudzi mudiki weropa unobatanidza tsinga huru mbiri pedyo nemoyo, uye inofanirwa kuvhara zvakasikwa mukati memazuva mashoma ekutanga ehupenyu.
Kana mudzi uyu ukagara wakavhurika muvacheche vasati vazvarwa, unogona kukonzera matambudziko ekufema uye kuisa kushushikana kwakawanda pamoyo. Mushonga unoshanda nekudzivisa makemikari akati wandei mumuviri anochengeta mudzi uyu wakavhurika, zvichiita kuti uvharike zvakasikwa sezvawaifanira kuita mushure mekuberekwa.
Dzimwe nguva vanachiremba vanogona kushandisawo mushonga uyu kubatsira kuderedza fivha kana kuzvimba muvacheche vachangozvarwa kana dzimwe nzira dzekurapa dzisina kukodzera. Zvisinei, PDA kuvhara ndiyo yainyanya kushandiswa uye yakakosha munzvimbo dzekuchipatara.
Ibuprofen lysine inofungidzirwa semushonga une simba zvine mwero unoshanda nekudzivisa ma enzymes anonzi cyclooxygenases (COX enzymes). Aya ma enzymes anogadzira zvinhu zvinonzi prostaglandins, izvo zvinochengeta ductus arteriosus yakavhurika panguva yekuzvitakura uye muhupenyu hwekutanga.
Nokuderedza ma prostaglandins aya, mushonga uyu unobvumira tsandanyama yakatsetseka mumadziro etsinga dzeropa kuti idzivire uye ivhare muromo. Maitiro aya anowanzoitika mukati me24 kusvika 48 maawa mushure mekurapa, kunyangwe mamwe mwana angada mishonga yakawanda.
Chikamu che lysine chemushonga chinobatsira kuita kuti ibuprofen inyungudike mumvura, zvinoreva kuti inogona kupiwa zvakachengeteka kuburikidza nemutsara we IV. Izvi zvinobatsirawo mushonga kuti ushande nekukurumidza kupfuura mafomu emuromo sezvo ichienda zvakananga muropa.
Ibuprofen lysine inogara ichipiwa nevashandi vakadzidziswa vechipatara kuburikidza nemutsara we IV, kwete nemuromo kana kumba. Mushonga uyu unouya seupfu hunosanganiswa nevanamukoti kana vanachiremba nemvura yakachena vasati vaupa kumwana wako.
Mushonga uyu unopiwa zvishoma nezvishoma kwemaminitsi anenge gumi nemashanu kuburikidza nemutsara we IV. Mwana wako haafaniri kudya kana kunwa chero chinhu chakakosha asati kana mushure mekutambira mushonga uyu sezvo uchienda zvakananga muropa ravo.
Vana vazhinji vanogamuchira kurapwa uku vachiri mu neonatal intensive care unit (NICU) kana special care nursery. Chikwata chekurapa chichatarisa zvakanyanya kurova kwemoyo kwemwana wako, kufema, uye zvimwe zviratidzo zvakakosha panguva uye mushure meimwe dose.
Nzira yekurapa inowanzoita inosanganisira mishonga mitatu inopiwa mumazuva akati wandei, kazhinji ine maawa makumi maviri nemana pakati peimwe dose. Vana vazhinji vanopindura zvakanaka kune urongwa hwekurapa hwakajairika, nePDA ichivhara zvachose mukati memazuva mashoma.
Kana nzira yekutanga isingashande, chiremba wako angakurudzira akateedzana echipiri emishonga mitatu mushure mekumirira mazuva mashoma. Zvisinei, kana PDA ichiri kusavhara mushure mekurapa kwakazara, mwana wako angada imwe nzira yekurapa.
Nguva yese yekurapa haiwanzodariki vhiki rimwe, uye vacheche vazhinji vanoona kuvandudzika mushure mejekiseni rekutanga kana rechipiri. Chikwata chako chekurapa chichashandisa bvunzo dze ultrasound kuti chitarise kana PDA ichivhara zvakanaka panguva yekurapa.
Kufanana nemishonga yese, ibuprofen lysine inogona kukonzera mhedzisiro, kunyangwe vacheche vazhinji vachizvigamuchira zvakanaka. Chikwata chekurapa chinotarisa izvi zvakanyatsonaka nekuti vacheche havagoni kutiudza kuti vari kunzwa sei.
Heano mhedzisiro yakajairika iyo vanachiremba vanotarisa panguva yekurapa:
Izvi zvinowanzoitika zvinowanzo gadziriswa nekukurumidza uye hazvikonzeri matambudziko anogara kwenguva refu kana akabatwa nekukurumidza.
Mhedzisiro yakakomba haina kujairika asi inoda kutariswa nekukurumidza kubva kuchikwata chako chekurapa:
Vashandi vechipatara vanotarisa izvi zvinokanganisa zvakanyanya nguva dzese, vachishandisa bvunzo dzeropa uye zvimwe zviyero kuti vabatise chero matambudziko nekukurumidza.
Zvimwe zvisingawanzoitiki asi zvakakosha mhedzisiro zvinogona kukura nekufamba kwenguva, kusanganisira matambudziko ekunzwa kana nyaya dzakaoma dzeitsvo. Chikwata chako chekurapa chemwana chichaenderera mberi nekutarisa kunyangwe mushure mekunge kurapwa kwapera kuti uve nechokwadi chekuti zvese zviri kupora zvakanaka.
Vacheche vakati havagone kugamuchira ibuprofen lysine zvakachengeteka nekuda kwezvimwe zvirwere kana mamiriro ezvinhu. Chikwata chako chekurapa chinonyatsoongorora mufananidzo wehutano hwemwana wako usati warumbidza kurapwa uku.
Vacheche vasingafaniri kugamuchira mushonga uyu vanosanganisira avo vane:
Mukuwedzera, vacheche vasati vazvarwa (vasiri pasi pemavhiki makumi matatu nemaviri ekuzvitakura) kana avo vanorema isingasviki 1.5 pounds vangave vasiri vakanaka vekurapwa uku.
Vamwe vacheche vangave vasina kukodzera kurapwa kana vaine matambudziko akakomba emapapu, vari pamimwe mishonga, kana vane mamwe mamiriro akaoma ekurapa. Neonatologist yako ichaongorora zvese izvi zvinhu zvakanyatso chenjerera isati yaita sarudzo dzekurapa.
Ibuprofen lysine yekujekesa inowanikwa pasi pemazita akati wandei emhando, neNeoProfen ndiyo inonyanya kushandiswa muUnited States. Dzimwe nyika dzinogona kuve nemazita akasiyana emhando yemushonga mumwechete.
Zvisinei nezita remhando, ese mavhezheni ane chinhu chimwe chete chinoshanda uye anoshanda nenzira imwechete. Pharmacy yechipatara ichagadzirira chero vhezheni yavanayo, uye ese anoshanda zvakaenzana pakurapa PDA.
Kana ibuprofen lysine isina kukodzera mwana wako kana isingashande nemazvo, vanachiremba vane dzimwe sarudzo dzekurapa dziripo. Sarudzo inoenderana nemamiriro chaiwo emwana wako uye hutano hwese.
Imwe nzira huru yekurapa ndeye indomethacin, mumwe mushonga unoshanda zvakafanana kuvhara PDA. Vamwe vacheche vanopindura zviri nani kune mushonga mumwechete pane mumwe, uye chiremba wako angangoda kuyedza indomethacin kana ibuprofen lysine isingashande.
Kana vacheche vasingakwanisi kugamuchira mushonga chero upi zvake zvakachengeteka, kuvharwa kwePDA nekuvhiyiwa ndiyo imwe sarudzo. Izvi zvinosanganisira maitiro madiki ekuvhara tsinga yeropa zvachose, kazhinji anoitwa nachiremba wevana anovhiya moyo.
Dzimwe nguva vanachiremba vanogona kukurudzira kungotarisa PDA vasina kurapwa nekukurumidza, kunyanya kana mwana wako aine hutano hwakanaka uye gomba racho rakakura. Mazhinji ePDAs madiki anozvivhara ega sezvo vacheche vachikura vaine simba.
Vose ibuprofen lysine ne indomethacin ndiyo mishonga inoshanda yekuvhara PDA muvana vachangozvarwa, uye tsvakurudzo inoratidza kuti inoshanda zvakaenzana zvakanaka kuvacheche vazhinji. Sarudzo pakati pavo inowanzouya pasi pezvinodiwa nehutano hwemwana wako uye mushonga unogona kuva wakachengeteka.
Ibuprofen lysine inogona kuva yakapfava pamatsvo uye kukonzera shanduko shoma mukuyerera kweropa kuenda muuropi nemamwe nhengo. Izvi zvinogona kuita kuti ive sarudzo iri nani kuvacheche vakatove vaine matambudziko ematsvo kana mamwe matambudziko.
Indomethacin yakashandiswa kwenguva refu uye inogona kushanda nekukurumidza mune dzimwe nguva, asi inogona kuva nemigumisiro yakawanda pabasa rematsvo uye kuyerera kweropa. Chikwata chako chekurapa chichasarudza mushonga wakachengeteka uye unogona kushanda zvakanaka mumamiriro ezvinhu emwana wako.
Mishonga yose miviri inoda kutariswa zvakanyanya uye ine mitengo yakafanana yekubudirira yekuvhara PDAs, saka chero ipi zvayo inogona kuva sarudzo yakanaka kana ichishandiswa zvakakodzera.
Ibuprofen lysine inowanzova yakachengeteka kuvacheche vane PDA, iyo pachayo imamiriro emoyo. Zvisinei, vacheche vane zvimwe zvikanganiso zvakakomba zvemtima kana kutadza kwemoyo vangasava vakanaka kune kurapwa uku.
Chiremba wemoyo wemwana wako uye chiremba wevana vachashanda pamwechete kuti vaone kana mushonga uyu wakachengeteka zvichienderana nerudzi rwakati uye kuoma kwezvimwe zvinonetsa zvemoyo. Vachafunga kuti moyo wemwana wako uri kushanda zvakanaka sei uye kana kuvhara PDA kuchabatsira kana kukonzera mamwe matambudziko.
Kana ukaona chero shanduko mumwana wako panguva kana mushure mekurapa, udza mukoti wako kana chiremba nekukasira. Sezvo mwana wako ari muchipatara, timu yezvokurapa iri kuramba ichiongorora chero matambudziko.
Zviratidzo zvingakufadza zvinosanganisira shanduko mumavara eganda, kurara zvisina kujairika kana kusagadzikana, shanduko mumaitiro ekufema, kana kana mwana wako achioneka asinganzwe zvakanaka. Rangarira kuti timu yezvokurapa iriwo kutarisa zvinhu izvi, asi zvaunoona semubereki zvinogara zvichikosha.
Sezvo ibuprofen lysine ichipiwa muchipatara, kupotsa dose hakuiti netsaona. Kana dose ichida kunonoka nekuda kwemamiriro emwana wako kana zvimwe zvekutanga zvezvokurapa, timu yako yezvokurapa ichagadzirisa nguva zvakakodzera.
Mishonga inoshanda zvakanyanya kana ichipiwa panguva yakarongwa, asi kunonoka kudiki kazhinji hakukanganisi kubudirira kwekurapa. Madhokotera ako achaita shuwa kuti mwana wako anogamuchira kurapa kwakazara nenzira yakachengeteka sezvinobvira.
Kurapa kunowanzo kumira mushure mekurapa kwakarongwa kwemadosi matatu, kana nekukurumidza kana bvunzo dzichiratidza kuti PDA yakavharwa zvachose. Timu yako yezvokurapa inoshandisa bvunzo dze ultrasound kuti iongorore kana tsinga yeropa iri kuvhara zvakanaka mushure meimwe dose.
Kana matambudziko akakomba akaitika, madhokotera ako anogona kumisa kurapa nekukurumidza uye kufunga nezvemimwe sarudzo. Sarudzo yekuramba kana kumisa kurapa inogara ichienderana nezvakachengeteka uye zvakanakira mwana wako panguva iyoyo.
Hongu, mwana wako achada kuongororwa ne ultrasound kuti ave nechokwadi chekuti PDA inoramba yakavharwa mushure mekurapwa kwapera. Vana vazhinji vanodawo kuongororwa ropa kuti vaone kuti basa reitsvo rinodzoka zvakajairika.
Kuchengetwa kwenguva refu nachiremba wevana wemoyo zvinowanzo kurudzirwa kuti vatarise hutano hwemoyo wemwana wako sezvavanokura. Mashoko akanaka ndewekuti vana vane PDAs dzakavharwa zvakabudirira nemishonga vanowanzoita zvakanaka kwenguva refu uye vane basa remoyo rakajairika.