Chii chinonzi Iloprost: Zvinoshandiswa, Madosi, Migumisiro uye Zvimwe

Iloprost mushonga wakakosha unobatsira kuvhura tsinga dzeropa mumapapu ako kana dzakamanikana zvinotyisa. Iyo vhezheni yekugadzirwa yechinhu chechisikigo chinogadzirwa nemuviri wako chinonzi prostacyclin, iyo inochengetedza ropa richiyerera zvakanaka kuburikidza nemitsipa yako.

Uyu mushonga unofemwa unoshandiswa zvakanyanya kurapa pulmonary arterial hypertension (PAH), mamiriro akakomba apo ropa rinomanikidzwa mumitsipa yako yemumapapu rinova rakanyanya kukwirira. Paunofema iloprost kuburikidza ne nebulizer yakakosha, inoenda zvakananga kunoshanda ichizorodza tsinga dzeropa dzakasimba, zvichiita kuti moyo wako uwedzere kuburitsa ropa mumapapu ako.

Chii chinonzi Iloprost chinoshandiswa?

Iloprost inorapa pulmonary arterial hypertension, mamiriro apo tsinga diki mumapapu ako dzinova dzakakora uye dzakamanikana. Izvi zvinoita kuti moyo wako ushande zvakanyanya kuburitsa ropa mumapapu ako, izvo zvinogona kukonzera kukundikana kwemoyo kana zvikasabatwa.

Mushonga uyu unotenderwa zvakanyanya kune vanhu vane PAH vane zviratidzo zvepakati kusvika zvakanyanya. Chiremba wako anogona kuuraira kana uri kusangana nekufema, kurwadziwa muchipfuva, kana kuneta kunodzora mabasa ako emazuva ese. Zvinobatsira zvikuru kune vanhu vasina kupindura zvakanaka kune dzimwe nzira dzekurapa PAH.

Dzimwe nguva vanachiremba vanoshandisawo iloprost kune zviitiko zvakakomba zveRaynaud's phenomenon, uko tsinga dzeropa mumunwe wako netsoka dzinomanikana zvine kurwadziwa semhinduro kuchitonhora kana kushushikana. Muzviitiko zvisingawanzoitiki, zvinogona kurairwa kune mamwe marudzi eropa mumapapu, kunyangwe izvi zvisiri kushandiswa kwayo kukuru.

Iloprost inoshanda sei?

Iloprost inoshanda nekutevedzera prostacyclin, chinhu chakasimba chechisikigo chinogadzirwa nemuviri wako kuti uchengetedze tsinga dzeropa dzakazorora uye dzakavhurika. Paunofema mushonga, unoenda zvakananga kumitsipa midiki yeropa mumapapu ako uko kwaunodiwa zvakanyanya.

Kana wasvika ipapo, iloprost inoudza masero emhasuru akatsetseka mumadziro emidziyo yeropa rako kuti azorore uye awedzere. Iyi nzira, inonzi vasodilation, inobva yaderedza kumanikidzwa mumitsipa yako yemumapapu. Mushonga uyu unobatsirawo kudzivirira ropa kuti risagwambe uye unoderedza kuzvimba mumadziro emidziyo yeropa.

Funga nezvazvo sekuzarura hose yemugadheni yakavharika chikamu - kana nzira yacho yakawedzera, mvura inoyerera nyore nyore. Iloprost inoonekwa semushonga une simba zvishoma unopa rubatsiro rwakanangana zvakananga panowanikwa dambudziko, panzvimbo pokukanganisa hurongwa hwako hwese hwekufambisa ropa.

Ndingatora sei Iloprost?

Iloprost inofanira kufemwa uchishandisa mudziyo unokosha we nebulizer uyo chikwata chako chehutano chichakupa uye kukudzidzisa kushandisa nemazvo. Iwe unowanzoitora ka6 kusvika ka9 pazuva, uchipatsanura zviyero maawa anenge 2 kusvika ku3 panguva yaunenge wakamuka.

Chikamu chimwe nechimwe chekufema chinotora maminitsi anenge 5 kusvika ku15 kuti apedze. Iwe uchafema zvakajairika nemuromo we nebulizer apo muchina unochinja mushonga wemvura kuita mhute yakanaka inosvika kudzika mumapapu ako. Zvakakosha kugara wakamira panguva yekurapa uye kufema zvinyoro nyoro uye zvakadzama.

Unogona kutora iloprost uine kana pasina chikafu, asi vanhu vazhinji vanozviwana zviri nyore kuronga nezvekudya sezvo uchizotora kakawanda zuva rese. Ita shuwa yekuchenesa midziyo yako ye nebulizer mushure meimwe neimwe yekushandisa zvinoenderana nemirairo yemugadziri kudzivirira zvirwere.

Usambofa wakavhenganisa iloprost nemimwe mishonga mune imwechete nebulizer kunze kwekunge wairairwa zvakananga nachiremba wako. Chengeta mabhodhoro asina kuvhurwa mufiriji, asi rega asvike tembiricha yekamuri usati waashandisa.

Ndingatora Iloprost kwenguva yakareba sei?

Vanhu vazhinji vane pulmonary arterial hypertension vanofanira kutora iloprost kwenguva refu kuti vatarise mamiriro avo nemazvo. PAH imamiriro echronic anoda kurapwa kuri kuenderera mberi kuti zviratidzo zvirambe zvichidzorwa uye kudzivirira chirwere kubva pakuwedzera.

Chiremba wako achatarisa maitiro ako kumushonga uyu kuburikidza nekutarisa nguva dzose, kusanganisira bvunzo dzinoyera kuti moyo wako nemapapu ako ari kushanda sei. Kana iloprost iri kukubatsira kuti unzwe zviri nani uye mhedzisiro yebvunzo yako inoratidza kuvandudzwa, ungangodaro ucharamba uchiitora zvachose.

Vamwe vanhu vangada kuchinja kumishonga yakasiyana kana kuwedzera mamwe marapirwo nekufamba kwenguva sezvo mamiriro avo achichinja. Usambomira kutora iloprost kamwechete usina kutanga wataura nachiremba wako, sezvo izvi zvingaita kuti zviratidzo zvako zvidzoke nekukurumidza uye zvingangokonzera matambudziko ane njodzi.

Ndezvipi Zvakaipa zveIloprost?

Semishonga yese, iloprost inogona kukonzera mhedzisiro, kunyangwe vanhu vazhinji vachizvigamuchira zvakanaka kana vangojaira kurapwa. Mhedzisiro yakajairika ine chekuita nemhedzisiro yekuvhura tsinga dzeropa mumuviri wako wese.

Heano mhedzisiro yaungasangana nayo, kutanga neaya akajairika anokanganisa vanhu vazhinji:

• Kurwadziwa kwemumashaya kana kurwadziwa kwemhasuru - Izvi zvinoitika nekuti iloprost inokanganisa kuyerera kweropa kumhasuru dzemumashaya panguva yekutsenga
• Kutemwa nemusoro - Kazhinji nyoro uye kazhinji inogadzirisa muviri wako paunojaira mushonga
• Kutsva kana kunzwa kudziya - Chiso chako nechipfuva zvinogona kunzwa kupisa sezvo tsinga dzeropa dzichivhura
• Kusvotwa kana dumbu rinogumbuka - Kutora mushonga uyu nechikafu dzimwe nguva kunobatsira
• Dizziness kana lightheadedness - Kunyanya kana uchimuka nekukurumidza
• Kukosora kana kugumbuka kwehuro - Kubva mukufema kwacho

Mhedzisiro iyi yakajairika inowanzo manejwa uye inowanzoita isinganyanyi kunetsa sezvaunoramba uchirapwa. Zvisinei, unofanira kubata chiremba wako kana vakava vakakomba kana kukanganisa mabasa ako ezuva nezuva.

Mhedzisiro isingawanzoitiki asi yakakomba inogona kuitika, uye unofanira kutsvaga rubatsiro rwekurapa kana ukasangana neimwe yeiyi:

• Kuderera kukuru kweropa - Zvichikonzera kufenda, dzungu guru, kana kuvhiringidzika
• Kurova kwemoyo nekukurumidza kana kusina kujairika - Moyo wako ungamhanya kana kusvetuka kurova
• Kurwadziwa muchipfuva - Zvakasiyana nezviratidzo zvako zvenguva dzose zvePAH
• Matambudziko akakomba ekufema - Kufema kunowedzera kuoma kana kuchema
• Zviratidzo zvehutachiona hwemapapu - Fivha, sputum ine mavara, kana kukosora kunowedzera

Zvisingawanzoitiki asi zvinogona kuva nematambudziko akakomba zvinosanganisira maitiro akakomba ekuita allergic, matambudziko akakosha ekubuda ropa, kana kudonha kunotyisa kweropa kunoda kutarisirwa kwekurapa nekukurumidza. Kunyange zvazvo izvi zvisingawanzoitiki, zvakakosha kuziva zviratidzo zvekuyambira uye kutsvaga rubatsiro nekukurumidza kana zvikaonekwa.

Ndiani Asingafaniri Kutora Iloprost?

Iloprost haisi yakachengeteka kumunhu wese, uye chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akuvimbisa. Vanhu vane mamiriro emoyo akati wandei kana avo vari kutora mishonga yakati wandei vangave vasiri vakanaka vekurapa uku.

Haufaniri kutora iloprost kana uine chero mamiriro aya:

• Chirwere chemoyo chakakomba - Kusanganisira kurwisa kwemoyo kuchangobva kuitika, angina isina kugadzikana, kana matambudziko akakomba ekurova kwemoyo
• Kuderera kwakanyanya kweropa - Iloprost inogona kuderedza ropa zvakare
• Matambudziko ekubuda ropa ari kushanda - Mushonga unogona kuwedzera njodzi yekubuda ropa
• Chirwere chechiropa chakakomba - Muviri wako haugone kugadzirisa mushonga nemazvo
• Kuzivikanwa allergy kuiloprost kana mishonga yakafanana - Kusanganisira mamwe madhiragi eprostacyclin

Chiremba wako achavawo akangwarira nezvekupa iloprost kana uine matambudziko eitsvo, une pamuviri kana kuyamwisa, kana kutora zvinoderedza ropa. Mishonga yakati wandei inogona kuita zvisina kunaka neiloprost, kunyanya avo vanoderedzawo ropa.

Vanhu vane makore anopfuura 65 vangada kutarisiswa zvakanyanya nekuti vanogona kuona mhedzisiro yakaipa. Nguva dzose udza chiremba wako nezve mishonga yese, zvinowedzera, uye zvigadzirwa zvemiti zvauri kutora usati watanga iloprost.

Mazita eBrand eIloprost

Iloprost inowanikwa pasi pemazita akati wandei ebrand zvichienderana nenzvimbo yako uye chimiro chaiyo. MuUnited States, zita rinowanzozivikanwa rebrand ndiVentavis, iyo ndiyo fomu inofemwa inoshandiswa kune pulmonary arterial hypertension.

Mamwe mazita ebrand aunogona kusangana nawo anosanganisira Ilomedin, iyo inoshandiswa mune dzimwe nyika yekutarisirwa kwe intravenous. Dzimwe nzvimbo dzinogona kuve nemamwe mazita ebrand kana shanduro dzakajairika dziripo. Murapi wako wemishonga anogona kukubatsira kuziva kuti ndeipi chaiyo brand kana formulation yaunogamuchira.

Zvisinei nezita rebrand, chinhu chinoshanda chakafanana, asi nzira yekutumira uye kuwanda zvinogona kusiyana. Nguva dzose shandisa chigadzirwa chaicho chakarairwa nachiremba wako uye usatsive pakati pemhando dzakasiyana pasina kutungamirirwa kwekurapa.

Zvimwe Zvinhu zveIloprost

Mishonga yakati wandei inogona kurapa pulmonary arterial hypertension kana iloprost isiri yako kana isiri kushanda zvakanaka. Chiremba wako angangofunga nezve izvi zvimwe zvinhu zvichienderana nemamiriro ako chaiwo uye maitiro ako ekurapa.

Mamwe mishonga yakavakirwa pa prostacyclin anosanganisira epoprostenol (Flolan), iyo inopihwa kuburikidza nekuenderera mberi kwe IV infusion, uye treprostinil (Remodulin), iyo inogona kupihwa sejojo pasi peganda, kuburikidza ne IV, kana semushonga unofemwa. Izvi zvinoshanda zvakafanana neiloprost asi vane nguva dzakasiyana dzekuyera uye mhedzisiro yezvinhu.

Mhando dzakasiyana dze mishonga yePAH dzinosanganisira endothelin receptor antagonists senge bosentan (Tracleer) uye ambrisentan (Letairis), iyo inoshanda nekudzivisa zvinhu zvinokonzera kuti tsinga dzeropa dzidzikire. Phosphodiesterase-5 inhibitors senge sildenafil (Revatio) uye tadalafil (Adcirca) inobatsira tsinga dzeropa kuti dzizorore kuburikidza nemumwe mutemo.

Mishonga mitsva senge riociguat (Adempas) inoshanda pane imwe nzira yekubatsira tsinga dzeropa kuti dzirambe dzakavhurika. Vanhu vazhinji vane PAH vanopedzisira vachitora musanganiswa wemishonga iyi kuti vawane mhedzisiro yakanaka.

Ko Iloprost Zviri Nani Kudarika Epoprostenol?

Zvese iloprost uye epoprostenol mishonga ye prostacyclin inoshanda zvakafanana kurapa PAH, asi vane misiyano yakakosha inoita kuti imwe neimwe ive yakakodzera vanhu vakasiyana. Hapana imwe iri yese

Iloprost inoda kuongororwa zvakanyatsonaka muvanhu vane chirwere chemoyo nekuti inogona kukanganisa ropa uye rhythm yemoyo. Chiremba wemoyo wako achada kuongorora kana mabhenefiti achipfuura njodzi yechirwere chako chemoyo.

Vanhu vane chirwere chemoyo chakagadzikana vangave vachikwanisa kushandisa iloprost zvakachengeteka nekutarisa pedyo, asi avo vane angina isina kugadzikana, kurwisa kwemoyo kwemazuva ano, kana matambudziko akakomba e rhythm yemoyo kazhinji havagone kushandisa mushonga uyu. Chiremba wako anogona kuda kuita bvunzo dzemoyo usati watanga kurapwa uye kukutarisa zvakanyanya mushure.

Ndingaita Sei Kana Ndikashandisa Iloprost Yakawandisa Netsaona?

Kana netsaona ukatora imwe dose ye iloprost, taura nachiremba wako kana nzvimbo yekudzora muchetura nekukasira. Kutora zvakawandisa kunogona kukonzera kudonha kunotyisa kweropa, kurwadziwa kwemusoro kwakanyanya, kusvotwa, kana kufenda.

Usaedze "kusvetuka" dose yako inotevera kuti ugadzirise imwe yakawedzerwa - izvi zvinogona kukonzera kuti zviratidzo zvako zvePAH zviwedzere. Pane kudaro, tsvaga mazano ekurapa ekuti ungaita sei zvakachengeteka. Chengeta nguva yako yekushandisa mushonga kuti udzivise tsaona dzemunguva yemberi, uye funga kushandisa sisitimu yekuyeuchidza mushonga.

Ndingaita Sei Kana Ndikakanganwa Dose yeIloprost?

Kana ukakanganwa dose ye iloprost, itore paunorangarira, kunze kwekunge yava nguva yechikamu chako chinotevera. Usatore zvikamu zviviri panguva imwe chete kuti ugadzirise imwe yakarasika, nekuti izvi zvinogona kukonzera mhedzisiro.

Edza kudzokera pane yako nguva yakajairika nekukurumidza sezvinobvira. Kukanganwa zvikamu zvakawanda kunogona kubvumira zviratidzo zvako zvePAH kudzoka, saka zvakakosha kuchengetedza kurapwa nguva dzose. Kana iwe uchikanganwa zvikamu kazhinji, taura nachiremba wako nezve nzira dzekukubatsira kurangarira.

Ndingamira Rini Kutora Iloprost?

Haufanire kumira kutora iloprost usina kutanga kutaura nachiremba wako, kunyangwe uchinzwa zviri nani. PAH imamiriro akareba anoda kurapwa kuri kuenderera mberi kudzivirira zviratidzo kubva pakudzoka uye chirwere kubva pakuenderera mberi.

Chiremba wako achagara achiongorora kana iloprost ichiri kurapa kwako zvakanaka uye anogona kuchinja mishonga yako zvichienderana nekuti uri kupindura sei. Kana uchida kumisa iloprost, chiremba wako anogona kukuchinjira kune imwe mushonga wePAH pane kumisa kurapwa kwese zvachose.

Ndingafamba ndichitora Iloprost here?

Hongu, unogona kufamba uchitora iloprost, asi zvinoda kuronga pachine nguva kuti uve nechokwadi chekuti une mushonga wakakwana uye unogona kuchengetedza nguva yako yekushandisa mishonga. Unozofanira kuuya nemidziyo yako ye nebulizer uye zvimwe zvekushandisa mishonga kana paine kunonoka.

Paunenge uchibhururuka, takura iloprost yako uye nebulizer mumutoro wako wekutungamira netsamba kubva kuchiremba wako ichitsanangura zvaunoda zvekurapa zvemidziyo. Bata kambani yako yendege pachine nguva nezvekufamba nemidziyo yekurapa. Kune rwendo rwemunyika dzese, tsvaga kana mushonga wako uri pamutemo munyika yaunoenda uye uuye nezvimwe zvekushandisa kana paine mamiriro ekukurumidzira.