Chii chinonzi Immune Globulin (HIZENTRA): Zvinoshandiswa, Dosage, Migumisiro Yemativi uye Zvimwe

Immune globulin subcutaneous, inozivikanwa zvakajairika nezita rekuti HIZENTRA, isarudzo yakacheneswa yemuviri inojekeswa pasi peganda rako kusimbisa immune system yako. Mushonga uyu une ma antibodies anodzivirira akaunganidzwa kubva kuzviuru zvevanopa ropa vane hutano, vachipa muviri wako simba rekutarisana nezvirwere raunoda kana immune system yako isiri kushanda nemazvo.

Kana wakamiswa mushonga uyu, unogona kunge uine mamiriro apo muviri wako haugadziri ma antibodies akakwana ega. Funga nezvazvo sekupa immune system yako mauto ekutsigira kana dziviriro yako yechisikigo iri kushanda zvishoma.

Chii chinonzi Immune Globulin chinoshandiswa?

Immune globulin subcutaneous inorapa zvirwere zve primary immunodeficiency, mamiriro apo immune system yako inoberekwa isingakwanise kugadzira ma antibodies anodzivirira akakwana. Izvi hazvisi zvirwere zvakajairika, asi zvinogona kukuitira kuti utapukirwe nezvirwere zvakakomba, zvinowanzoitika izvo muviri wako unonetseka kurwisa zvakasikwa.

Chiremba wako angangokumisira mushonga uyu kana uine mamiriro akaita se common variable immunodeficiency, X-linked agammaglobulinemia, kana severe combined immunodeficiency. Mamiriro aya anonzwika akaoma, asi ese anogovana chinhu chimwe chete: muviri wako unoda rubatsiro rwekugadzira ma antibodies anochengeta zvirwere kure.

Dzimwe nguva vanachiremba vanoshandisawo mushonga uyu kune secondary immunodeficiencies, uko chimwe chirwere kana kurapwa kwakaita kuti immune system yako isashande zvakanaka. Izvi zvinogona kuitika kana uri kugamuchira mamwe marapirwo ekenza kana uine mamiriro anokanganisa kugona kwemuviri wako kugadzira ma antibodies.

Immune Globulin inoshanda sei?

Immune globulin inoshanda nekupa muviri wako ma antibodies akagadzirwa-akagadzirwa anogona kutanga kurwisa zvirwere nekukasira. Aya ma antibodies anobva muplasma yakabatanidzwa yezviuru zvevanopa vane hutano, saka ane dziviriro kubva kumajermi akawanda akasiyana uye mavairasi.

Paunobaya mushonga uyu pasi peganda rako, ma antibodies aya anopinda muropa rako uye anotenderera mumuviri wako wese. Anoshanda semapurotini echisikigo emuviri wako anorwisa zvirwere, achiziva mabhakitiriya anokuvadza nemavhairasi uye achivaisa kuti aparadzwe.

Izvi zvinoonekwa sekurapa kwakasimba uye kunoshanda kwekusashanda kwemuviri. Kusiyana nemimwe mishonga inongorapa zviratidzo, immune globulin inotsiva zviri kushaikwa mumuviri wako, ichikupa dziviriro chaiyo kubva kuzvirwere.

Ndingatora sei Immune Globulin?

Iwe uchabaya immune globulin pasi peganda remukati memukati memukati, dumbu, ruoko rwepamusoro, kana kumashure uchishandisa tsono diki uye sisitimu yepombi. Vanhu vazhinji vanoibaya kamwe pavhiki, kunyangwe chiremba wako achaziva chirongwa chaunoshanda zvakanyanya kune mamiriro ako.

Usati wajowa yega yega, rega mushonga uyu udziye kusvika pakupisa kwemukati kwemaminitsi angangoita 30. Usambofa wakaipisa mu microwave kana mumvura inopisa, sezvo izvi zvinogona kukuvadza ma antibodies. Unogona kudya zvakajairika usati wajowa uye mushure mekubaya, sezvo chikafu chisingakanganisi kuti mushonga unoshanda sei.

Vashandi vehutano vako vachakudzidzisa maitiro ekubaya mushonga zvakachengeteka kumba. Nzvimbo dzekubaya dzinofanirwa kutenderedzwa vhiki rega rega kudzivirira kutsamwa, uye unofanirwa kuchengeta nzvimbo dzekubaya padhuze neimwe inch kubva kune imwe uye kubva kune chero nzvimbo dzekubaya dzakapfuura.

Nguva dzose geza maoko ako zvakakwana usati wagadzirira kubaya kwako, uye shandisa nzira yakakodzera yekuchenesa kudzivirira kuisa mabhakitiriya mumuviri wako. Chengeta mabhodhoro asina kuvhurwa mufiriji, asi usambofa wakaomesa.

Ndingatora Immune Globulin kwenguva yakareba sei?

Vanhu vazhinji vane zvirwere zvekusashanda kwemuviri vanoda kutora immune globulin kwehupenyu hwese, sezvo mamiriro aya asingazvirapi pachavo nekufamba kwenguva. Muromo wako wekudzivirira muviri ucharamba uchida rutsigiro urwu kuti ukudzivirire kubva kuzvirwere.

Chiremba wako achatarisa mazinga ako emaantibody kuburikidza nemiedzo yeropa yenguva dzose kuti ave nechokwadi chekuti uri kuwana huwandu hwakakodzera hwekudzivirira. Miedzo iyi inobatsira kuona kana muyero wako uchida kugadziriswa kana kana chirongwa chekurapa chichifanira kuchinjwa.

Kana uri kutora immune globulin ye secondary immunodeficiency, unogona kukwanisa kumisa kurapwa kana mamiriro ako ari pasi achivandudzika kana mamwe marapirwo ako apera. Chiremba wako achakutungamira kuburikidza nesarudzo iyi zvichibva pamamiriro ako chaiwo.

Ndezvipi Zvakaipa zve Immune Globulin?

Vanhu vazhinji vanotsungirira immune globulin subcutaneous injections zvakanaka, asi unogona kusangana nemamwe maitiro akapfava, kunyanya paunotanga kurapwa. Muviri wako uri kugadzirisa kugamuchira maantibodies matsva aya, saka mamwe maitiro ekutanga akajairika.

Zvakajairika zvinokonzeresa izvo vanhu vazhinji vanosangana nazvo zvinosanganisira kuzvimba zvishoma, kutsvuka, kana kunyorova panzvimbo yekujekisisa. Maitiro aya anowanzoonekwa mukati memaawa mashoma ekujekisisa uye anowanzoenda mukati mezuva rimwe kana maviri. Unogonawo kuona kumwe kukwenya kana bundu diki, rakasimba paunojekesa mushonga.

Heano mativi anowanzoitika aunogona kusangana nawo:

• Kurwadziwa kudiki kana kusagadzikana panzvimbo dzekujekisisa
• Kutsvuka kana kuzvimba pasi peganda
• Musoro unovandudzika mukati me24 maawa ekujekisisa
• Kuneta kudiki kana kunzwa kusagadzikana
• Nausea kana kusagadzikana mudumbu
• Kurwadziwa kwemhasuru kana kurwadziwa kwemajoini

Zvizhinji zvezviratidzo izvi zvakapfava uye zvenguva pfupi, zvichivandudzika sezvo muviri wako uchijaira kurapwa. Vanhu vazhinji vanowana kuti mativi anokonzeresa anova asinganyanyi kuoneka mushure mejekiseni rekutanga.

Zvisingawanzoitiki asi zvakanyanya kukomba zvinokonzeresa zvinogona kuitika dzimwe nguva, kunyangwe zvichiwanzodiwa zvakanyanya ne subcutaneous injections zvichienzaniswa ne intravenous immune globulin. Maitiro aya anoda kutariswa kwekurapa nekukurumidza kana akavandudzika.

Hezvino zvinokonzeresa zvakanyanya zvekutarisa:

• Kusagadzikana kwakanyanya kwemuviri nekutadza kufema kana kumedza
• Mavanga akapararira kana hives achioneka nekukurumidza
• Kurwadziwa kwemusoro kwakanyanya nekukakama kwemutsipa kana kunzwa chiedza
• Kurwadziwa muchipfuva kana kutadza kufema
• Kusvotwa kwakanyanya nekutsvuka kusingaperi
• Zviratidzo zvezvinetso zveitsvo zvakaita sekuderera kwemvura kana kuzvimba mumakumbo

Kana ukaona chero zviratidzo izvi zvakakomba, taura nemupi wako wehutano nekukasira kana kutsvaga rubatsiro rwekurapa rwekukurumidza. Izvi zvinokonzeresa hazviwanzoitiki, asi zvinoda kurapwa nekukurumidza kana zvaitika.

Ndiani Asingafaniri Kutora Immune Globulin?

Immune globulin subcutaneous haina kuchengeteka kune vese, uye mamiriro ezvinhu kana mamiriro ezvinhu anoita kuti kurapwa uku kusakodzera kana kuva nenjodzi. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akurudzira mushonga uyu.

Haufaniri kutora immune globulin kana uine allergy yakanyanya kune vanhu antibodies kana chero chikamu chemushonga. Vanhu vane IgA kushomeka vakagadzira antibodies kurwisa IgA vanotarisana nenjodzi yakakwira yekusagadzikana kwakanyanya kwemuviri uye kazhinji havagone kushandisa kurapwa uku zvakachengeteka.

Vanhu vane zvimwe zvinetso zveitsvo vanoda kufunga zvakakosha, sezvo immune globulin dzimwe nguva inogona kuwedzera basa reitsvo. Chiremba wako achanyatso tarisa basa reitsvo yako kana uine nhoroondo yechirwere cheitsvo kana uri kutora mishonga inokanganisa itsvo dzako.

Hezvino mamiriro anogona kuita kuti immune globulin isakukodzere:

• Chirwere cheitsvo chakanyanya kana nhoroondo yekutadza kweitsvo
• Kuvhiringidzika kweropa kunoshanda kana mapundu eropa achangobuda
• Chirwere chemoyo chakanyanya chinoita kuti shanduko yemvura ive nenjodzi
• Kusagadzikana kwakanyanya kwemuviri kune zvigadzirwa zveropa
• Mamwe mamiriro eautoimmune anogona kuwedzera nekurapwa

Chiremba wako achayerera zvakanakira nezvakaipira zvinhu zvakakodzera mamiriro ako chaiwo uye anogona kukurudzira dzimwe nzira dzekurapa kana immune globulin isina kukodzera iwe.

Mazita eBrand eImmune Globulin

HIZENTRA ndiyo mhando yeimmune globulin inonyanya kunyorerwa yekudzivirira subcutaneous muUnited States. Mhando iyi yakadzidzwa zvakanyanya uye ine rekodhi refu yekuchengeteka uye kushanda mukurapa zvirwere zve primary immunodeficiency.

Dzimwe mhando dze subcutaneous immune globulin dzinosanganisira GAMUNEX-C, GAMMAKED, uye CUTAQUIG. Mhando imwe neimwe ine mafomula akasiyana zvishoma, asi ese ane zvinhu zvakafanana uye anoshanda nenzira dzakafanana kusimudzira immune system yako.

Chiremba wako achasarudza mhando chaiyo zvichienderana nezvido zvako, inishuwarenzi, uye ruzivo rwavo rwekurapa. Mhando dzese dzakabvumidzwa neFDA dzinopfuura kuyedzwa kwakanyanya kuti dzive nechokwadi chekuti dzinowana zviyero zvekuchengeteka nekushanda.

Zvimwe Zvinhu zveImmune Globulin

Intravenous immune globulin (IVIG) ndiyo imwe nzira huru yekudzivirira subcutaneous, inotumirwa zvakananga muropa rako kuburikidza nemitsi. Sarudzo iyi inoda kushanya kunzvimbo yekutarisira hutano mumasvondo 3-4 ega ega uye inotora maawa akati wandei kuti upedze infusion yega yega.

Vamwe vanhu vanosarudza IVIG nekuti inoda mazuva mashoma ekurapa pamwedzi, nepo vamwe vachisarudza subcutaneous injections kuti zvive nyore kurapwa kumba uye mazinga akagadzikana eantibody. Chiremba wako achakubatsira kusarudza kuti ndeipi sarudzo inokodzera mararamiro ako uye zvinodiwa zvekutanga.

Kune mamwe marudzi e immunodeficiency, mamwe marapirwo senge bone marrow transplant kana gene therapy anogona kufungwa, kunyangwe izvi zvakachengeterwa nyaya dzakanyanya. Kurapa uku kunotakura njodzi dzakawanda asi kunogona kupa mukana wekurapa panzvimbo pekurapa kutsiva hupenyu hwese.

Immune Globulin iri Nani Pane IVIG?

Subcutaneous immune globulin uye intravenous immune globulin zvese zvinoshanda pakurapa, asi imwe neimwe ine zvainokunda zvichienderana nemamiriro ako ezvinhu nezvaunoda. Hapana imwe iri nani pane imwe, sezvo sarudzo yakanaka ichienderana nezvaunoda.

Majekiseni eSubcutaneous anopa kusununguka kwakawanda uye nyore sezvo iwe uchigona kuita kumba pane yako pachako purogiramu. Ivo zvakare vanowanzoita kuti pave nezvishoma zvinokonzeresa matambudziko akadai semarwadzo emusoro kana zviratidzo zvakaita sefuruwenza, uye vanopa mazinga akagadzikana eantibody mukati mevhiki.

IVIG inogona kunge iri nani kana iwe uine dambudziko rekuzvipinza, uchida madosi akanyanya eantibodies, kana uine mamwe mamiriro ekurapa anoita kuti subcutaneous administration ive nematambudziko. Vamwe vanhu vanosarudzawo purogiramu yekurapa isingawanzoitiki kunyangwe nguva refu yekupinza.

Chiremba wako achafunga nezvezvinhu zvakaita sehupenyu hwako, purogiramu yebasa, kunyaradzwa nekuzvipinza, uye kuti muviri wako unopindura sei kune imwe neimwe mhando yekurapa paanoita chisarudzo ichi.

Mibvunzo Inowanzo Bvunzwa Nezve Immune Globulin

Ko Immune Globulin Yakachengeteka Kune Vanhu vane Chirwere cheShuga?

Hongu, immune globulin subcutaneous inowanzo chengeteka kune vanhu vane chirwere cheshuga, uye kuva nechirwere cheshuga hakukudzivise kuwana kurapwa uku. Zvisinei, uchada kutarisa mazinga eshuga yeropa zvakanyanya, sezvo vamwe vanhu vachiona shanduko diki mukudzora kwavo glucose pavanotanga immune globulin.

Mishonga pachayo haina huwandu hukuru hweshuga, asi immune response uye chero kushushikana pamuviri wako kubva pakutanga kurapwa kutsva dzimwe nguva kunogona kukanganisa mazinga eshuga yeropa. Chiremba wako achashanda newe kugadzirisa chirongwa chako chekugadzirisa chirwere cheshuga kana zvichidikanwa.

Ndoita Sei Kana Ndikashandisa Immune Globulin Yakawandisa Netsaona?

Kana ukabaya immune globulin yakawanda kupfuura yakarairwa netsaona, fonera chiremba wako nekukasira kuti akutungamirire. Kunyange zvazvo overdose diki isingakwanisi kukonzera kukuvadza kwakanyanya, unogona kuona migumisiro yakanyanya kuoneka yakadai sekuzvimba kwakawedzera panzvimbo dzekubaya kana zviratidzo zvakasimba zvakaita sefuruwenza.

Usaedze kutsiva nekusvetuka mushonga wako unotevera kana kuderedza mishonga yeramangwana wega. Chiremba wako anofanira kuongorora mamiriro acho ezvinhu uye kuona nzira yakanakisisa yekuchengetedza dziviriro yako uchideredza chero migumisiro isingadiwi.

Ndingaita Sei Kana Ndikakanganwa Dose ye Immune Globulin?

Kana ukakanganwa dose yakarongwa, ibaye pakarepo paunoyeuka, chero zvazvo zviri mukati mezuva kana maviri ezuva rako retsika. Kana mazuva anopfuura mashoma apfuura, fonera chiremba wako kuti akutungamirire pane kuwedzera dose yako inotevera.

Kukanganwa dose dzimwe nguva hakuzokusiye usina dziviriro nekukasira, sezvo immune globulin ichienderera mberi ichishanda mumuviri wako kwemazuva akati wandei. Zvisinei, dose dzakakanganwa nguva dzose dzinogona kuderedza mazinga ako emuviri uye kukusiya uchinyanya kutapukirwa nezvirwere.

Ndingamira Rini Kutora Immune Globulin?

Vanhu vazhinji vane zvirwere zvekusakwana kwekutanga vanoda immune globulin replacement therapy kwehupenyu hwavo hwose, sezvo mamiriro aya asingavandudzi ega. Muromo wako wekudzivirira muviri ucharamba uchida rutsigiro urwu kuti uchengetedze dziviriro yakakwana kubva kuzvirwere.

Kana uri kutora immune globulin ye secondary immunodeficiency, unogona kumisa kurapwa kana mamiriro ako ari pasi achigadzirisa kana mamwe marapirwo ako apera. Chiremba wako achaziva izvi kuburikidza nekuongorora nguva dzose mazinga ako emuviri uye basa rose rekudzivirira muviri.

Ndingafamba Here Ndichitora Immune Globulin?

Hongu, unogona kufamba uchitora immune globulin subcutaneous, kunyangwe zvichida kuronga kuti uve nemushonga wako nezvinhu zviripo. Unozofanira kuronga kuchengetwa kwakakodzera nekutakura mushonga wako, kunyanya kana uchifamba kwenguva yakareba.

Pakuenda nendege, unogona kutakura mushonga wako nezvinhu zvekujekesa mumutoro wako wekufambisa uine zvinyorwa zvakakodzera kubva kuna chiremba wako. Vanhu vazhinji vanowana zvichibatsira kubata kambani inogadzira mushonga wavo kuti vawane matungamirirwo ekufamba uye kutsvaga makemisi kana nzvimbo dzekurapa kwavanenge vachienda kana paine mamiriro ekukurumidzira.