Chii chinonzi Immune Globulin (IVIG): Zvinoshandiswa, Dosage, Side Effects uye Zvimwe

Immune globulin, inozivikanwawo seIVIG (intravenous immunoglobulin), chigadzirwa cheropa chakagadzirwa kubva kuma antibodies akapihwa nevakawanda vane hutano. Mushonga uyu unopa immune system yako simba nekuisa ma antibodies akagadzirwa anobatsira kurwisa zvirwere uye kudzikamisa immune responses yakanyanyisa. Funga nezvazvo sekukwereta simba kubva kune vamwe kana yako immune system ichida rubatsiro rwakawedzerwa.

Chii chinonzi Immune Globulin?

Immune globulin imhinduro yakanyanya ye antibodies dzakaunganidzwa kubva kuropa rakapiwa. Aya ma antibodies ndiyo mapuroteni anorwisa zvirwere ayo muviri wako unogadzira zvakasikwa, asi anobva kune vakawanda vanopa kuti akupe dziviriro yakakura. Maitiro ekugadzira anonyatsoongorora uye kuchenesa aya ma antibodies kuti aite kuti ave akachengeteka kushandiswa nemishonga.

Mushonga uyu une immunoglobulin G (IgG), iyo ndiyo mhando yakajairika ye antibody yemuviri wako. Ma antibodies akapihwa anomiririra immunity kubva kuzviuru zvevanhu, saka anogona kuziva uye kurwisa mabhakitiriya akasiyana siyana nezvirwere. Uku kuunganidzwa kwe immunity kunoita kuti IVIG ive nesimba rakanyanya kune vanhu vane immune systems dzisingashande zvakanaka.

Chii chinonzi Immune Globulin chinoshandiswa?

Vanachiremba vanoraira immune globulin nezvikonzero zviviri zvikuru: kutsiva ma antibodies asipo kana kudzikamisa immune system yakanyanyisa. Kana muviri wako usingakwanise kugadzira ma antibodies akakwana wega, IVIG inogona kuzadza gap iro uye kukubatsira kukudzivirira kubva kuzvirwere zvakakomba.

Mushonga uyu unotarisira mamiriro akati wandei apo immune system yako inoda rutsigiro. Heano mashandisiro makuru ayo chiremba wako angatarisa:

• Zvirwere zvekutanga zvekushaya simba remuviri (kana wakaberekwa uine immune system isina simba)
• Chronic inflammatory demyelinating polyneuropathy (CIDP), chirwere chemitsipa
• Idiopathic thrombocytopenic purpura (ITP), apo muviri wako unoparadza maplatelets awo
• Kawasaki chirwere muvana, chinokonzera kuzvimba kwemidzi yeropa
• Chronic lymphocytic leukemia ine hutachiona hunowanzoitika
• Multifocal motor neuropathy, chirwere chemitsipa chisingawanzoitiki

Vamwe vanachiremba vanoshandisawo IVIG kune mamwe mamiriro eautoimmune, kunyangwe kushandiswa uku kuchiri kudzidzwa. Murapi wako wehutano achanyatso kuyera mabhenefiti nenjodzi zvichibva pamamiriro ako chaiwo.

Immune Globulin Inoshanda Sei?

Immune globulin inoshanda nekupa ropa rako zvakananga huwandu hwemuviri hunorwisa hutachiona. Miviri iyi inotanga ipapo ipapo kupururudza mumuviri wako, ichitsvaga utachiona nezvimwe zvinotyisidzira zvavanogona kuziva nekudzivisa. Iyi nzira inotanga pakarepo mushonga wacho wapinda muropa rako.

Kune mamiriro ekushaya simba remuviri, IVIG inoshanda semushonga wekutsiva. Inopa miviri iyo muviri wako unofanirwa kunge uchigadzira asi usingakwanise kugadzira muhuwandu hwakakwana. Miviri yakakweretwa inoramba ichishanda mumuviri wako kwemavhiki akati wandei, ichikupa dziviriro panguva iyoyo.

Pakurapa mamiriro eautoimmune, IVIG inoshanda zvakasiyana. Inobatsira kudzikamisa immune system yako yakanyanyisa uye inoderedza kuzvimba. Nzira chaiyo haina kunyatsojeka, asi mushonga uyu unoita seunogadzirisa chiyero chemuviri wako uye kuderedza kuzvimba kunokuvadza.

Ndingatora Sei Immune Globulin?

Uchagamuchira immune globulin kuburikidza neIV line muruoko rwako, kazhinji muchipatara kana nzvimbo yekupinza. Iyi nzira inowanzo tora maawa 2-4, uye iwe uchatariswa nguva yese. Chikwata chako chehutano chichatanga kupinza zvishoma nezvishoma uye zvishoma nezvishoma kuwedzera kumhanya sezvo muviri wako uchigadzirisa.

Musati mapiwa mushonga uyu, munogona kudya zvakajairika uye munofanira kunwa mvura yakawanda kuti muve nemvura mumuviri. Vamwe vanachiremba vanokurudzira kutora acetaminophen (Tylenol) maminitsi makumi matatu musati mapiwa mushonga kuti mudzivise kutemwa nemusoro kana zvimwe zviratidzo zvidiki. Chiremba wenyu achakupai mirairo yakatarwa zvichienderana nezvido zvenyu.

Munguva yekuisa mushonga, munofanira kugara makadzikama asi munogona kuverenga, kuona TV, kana kuita zvimwe zviitiko zvakadzikama. Udza mukoti wako nekukasira kana ukanzwa dzungu, kutemwa nemusoro, kana kuona chero zviratidzo paganda. Vanhu vazhinji vanotsungirira kurapwa zvakanaka, kunyanya mushure mema session ekutanga.

Ndingatora Immune Globulin kwenguva yakareba sei?

Kureba kwekurapwa kunoenderana zvachose nemamiriro ako uye kuti unopindura sei kumushonga. Kune primary immunodeficiency, munogona kuda IVIG kwehupenyu hwese, ne infusions kazhinji mumasvondo 3-4 ega ega. Kurapwa uku kunobatsira kuchengetedza mazinga akagadzikana e antibody muropa rako.

Kune autoimmune conditions senge ITP kana CIDP, nguva yekurapwa inosiyana zvakanyanya. Vamwe vanhu vanoda madhiza mashoma chete, nepo vamwe vachida infusions yemwedzi nemwedzi kwemwedzi kana makore. Chiremba wako achatarisa zviratidzo zvako uye bvunzo dzeropa kuti aone nguva yakakodzera kwauri.

Usambomira kurapwa kwe IVIG kamwechete usina kutanga wataura nachiremba wako. Kune immune deficiency conditions, kumira kamwechete kungakusiya uchitambudzika nezvirwere zvakakomba. Chiremba wako achakubatsira kunzwisisa zvaunofanira kutarisira uye kuti zvingave riini zvakachengeteka kuderedza kana kumisa kurapwa.

Ndezvipi Zvakaipa zve Immune Globulin?

Vanhu vazhinji vanotsungirira immune globulin zvakanaka, asi semushonga chero upi zvake, unogona kukonzera zvakaipa. Zviratidzo zvakajairika zvinowanzoita zvidiki uye zvinoitika panguva kana nguva pfupi mushure mekuisa mushonga. Zvakaipa izvi zvinowanzoita nani nekumhanya kwekudzika kwekuisa mushonga kana pre-medication.

Heano zvakaipa zvidiki kusvika pakati nepakati zvaungasangana nazvo:

• Kurwadziwa nemusoro (mhedzisiro inowanzoitika)
• Kuneta kana kunzwa kuneta
• Muviri kusvotwa kana dumbu kusagadzikana
• Kurwadziwa kwemhasuru kana marwadzo emajoini
• Fivha diki kana kutonhora
• Meno paganda kana kukwenya
• Kurwadziwa kana kuzvimba panzvimbo yeIV

Mhedzisiro iyi inowanzo pera mukati mezuva rimwe kana maviri mushure mekurapwa. Chikwata chako chehutano chinogona kudzivirira kana kuderedza mhedzisiro iyi nekugadzirisa mwero wako wekudururwa kana kukupa pre-medication.

Kunyange zvazvo zvisingawanzoitiki, vamwe vanhu vanowana mhedzisiro yakakomba inoda kutariswa kwekurapa nekukasira. Mhedzisiro iyi isingawanzoitiki asi yakakosha inosanganisira:

• Maitiro akakomba ekuita allergic (anaphylaxis)
• Mavhiri eropa mumakumbo, mapapu, kana uropi
• Matambudziko eitsvo kana kukundikana
• Kurwadziwa kwemusoro kwakanyanya kungaratidza kuzvimba kwehuropi
• Kutadza kufema kana kurwadziwa muchipfuva
• Kuchinja kwemaziso kamwe kamwe

Chikwata chako chekurapa chinokutarisa zvakanyanya panguva uye mushure mekuiswa kuti uone mhedzisiro iyi yakakomba. Vanhu vazhinji havamboziva mhedzisiro iyi yakakomba, asi zvakakosha kuziva zviratidzo zvekuyambira.

Ndiani Asingafaniri Kutora Immune Globulin?

Immune globulin haina kuchengeteka kune vese, uye chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akuraira. Vanhu vane mamiriro akati wandei vanotarisana nenjodzi huru uye vanogona kuda dzimwe nzira dzekurapa kana matanho akakosha.

Haufanire kugamuchira IVIG kana uine maitiro akakomba ekuita allergic kune immunoglobulins kana chero zvinhu mumushonga. Vanhu vane selective IgA kushomeka vane anti-IgA antibodies vanotarisana nenjodzi huru yemaitiro akakomba ekuita allergic.

Mamiriro akati wandei ekurapa anoda kungwarira kwakanyanya kana uchifunga nezvekurapwa kweIVIG. Chiremba wako achayeresa mabhenefiti achipesana nenjodzi dzinogona kuitika kana uine:

• Zvirwere zveitsvo kana nhoroondo yematambudziko eitsvo
• Zvirwere zvemtima kana njodzi dzekuvharika kweropa
• Chirwere cheshuga kana pre-diabetes
• Nhoroondo yesitroko kana kuvharika kweropa
• Anemia yakakomba kana zvirwere zveropa
• Kubaiwa kwemajekiseni achangobva kuitwa ane hutachiona hupenyu

Kuzvitakura nekuyamwisa kazhinji hazvirevi kuti haugone kushandisa IVIG, sezvo mushonga uyu uchionekwa sewakachengeteka panguva idzi. Zvisinei, chiremba wako achakutarisa zvakanyatsonaka uye achakurukura chero zvinokunetsa zvinoenderana nemamiriro ako ezvinhu.

Mazita eBrand eImmune Globulin

Makambani akati wandei emishonga anogadzira zvigadzirwa zveimmune globulin, chimwe nechimwe chine mafomula akasiyana zvishoma uye kuwanda. Chiremba wako achasarudza zita chairo zvichienderana nemamiriro ako, kushivirira, uye kuwanikwa. Mazita akajairika ebrand anosanganisira Gammagard, Privigen, Octagam, uye Gammaplex.

Nepo zvigadzirwa izvi zvine mushonga mumwe chete, zvinogona kusiyana mune shuga, zvinochengetedza, kana mazinga esodium. Vamwe vanhu vanoshivirira mamwe mabhurandi zvirinani pane vamwe, saka chiremba wako anogona kuchinja mafomula kana ukaona mhedzisiro.

Kusarudzwa kwebrand kazhinji hakukanganisi kuti mushonga unoshanda sei kumamiriro ako. Chikwata chako chehutano chichasarudza sarudzo yakakodzera zvichienderana nezvido zvako uye nhoroondo yako yekurapa.

Zvimwe zvingashandiswa panzvimbo peImmune Globulin

Kune mamwe mamiriro, mamwe marapirwo anogona kuwanikwa kana IVIG isina kukodzera kana kushanda kwauri. Subcutaneous immunoglobulin (SCIG) inopa imwe sarudzo, kwaunogamuchira zvidiki zvidiki pasi peganda kazhinji, kazhinji kumba.

Zvimwe zvingashandiswa panzvimbo zvinoenderana nemamiriro ako chaiwo. Kune zvirwere zveautoimmune, chiremba wako anogona kufunga nezve corticosteroids, mamwe mishonga yekudzivirira immune, kana marapirwo matsva akatarwa. Kune kusashanda zvakanaka kwemuviri, kutamiswa kwemasero emuti unogona kuve sarudzo mune zviitiko zvakakomba.

Nzira yakanaka zvichienderana nekuongororwa kwako, kuoma kwezviratidzo, uye hutano hwako hwese. Chiremba wako achakurukura zvese zvingasarudzwa zviripo uye kukubatsira kunzwisisa zvakanakira nezvakaipira nzira imwe neimwe.

Ko Immune Globulin iri nani pane dzimwe nzira dzekurapa here?

Immune globulin haisi yakanaka zvakanyanya pane dzimwe nzira dzekurapa, asi inopa zvakanakira zvakasiyana kune mamwe mamiriro. Kune primary immunodeficiency, IVIG inopa kutsiva kwakananga kwemuviri wemuviri uyo mamwe mishonga asingakwanise kufananidza. Izvi zvinoita kuti ive nzira yekurapa yakajairika kune akawanda immune deficiency disorders.

Kune autoimmune conditions, IVIG inowanzo shanda kana dzimwe nzira dzekurapa dzakundikana kana dzisina kukodzera. Inowanzoita kuti ive nemhedzisiro shoma yenguva refu pane mamwe immunosuppressive drugs, zvichiita kuti ive sarudzo yakanaka kune vanhu vanoda kurapwa kwenguva refu.

Kurapa

Kupfuudzwa kwemishonga ye immune globulin netsaona hakusi kazhinji nekuti mushonga uyu unopiwa zvishoma nezvishoma pasi pekutariswa kwechiremba. Kana ukawana yakawanda, unogona kusangana nemigumisiro yakanyanya kuoma senge kurwadziwa kwemusoro kwakanyanya, kusvotwa, kana kuwanda kwemvura mumuviri. Chikwata chako chekurapa chichakutarisa zvakanyanya uye kukupa rubatsiro.

Kurapa kwekuwandisa kunotarisa pakugadzirisa zviratidzo uye kutsigira maitiro emuviri wako echisikigo. Vanhu vazhinji vanopora zvakanaka nekutarisirwa kwekurapa kwakakodzera, kunyangwe iwe ungada kugara muchipatara kuti utariswe.

Ndingaita Sei Kana Ndikakanganwa Dose ye Immune Globulin?

Kana ukakanganwa infusion ye IVIG yakarongwa, taura nechiremba wako nekukurumidza sezvinobvira kuti urongezve. Usamirira kusvika nguva yako inotevera yakajairika, kunyanya kana uine chirwere chekusadzivirirwa. Kukanganwa madosi kunogona kukusiya uchikwanisa kutapukirwa kana kubvumira zviratidzo zvako kuti zviwedzere.

Chiremba wako achasarudza nguva yakanakisa ye dose yako yekugadzirisa zvichibva panguva yaunogamuchira kurapwa kwekupedzisira uye mamiriro ako chaiwo. Vanogonawo kugadzirisa chirongwa chako mberi kudzivirira madosi akakanganwa mune ramangwana.

Ndingamira Rini Kutora Immune Globulin?

Sarudzo yekumisa immune globulin zvachose inoenderana nemamiriro ako ekutanga uye mhinduro yekurapa. Kune primary immunodeficiency, iwe ungangoda kurapwa kwehupenyu hwese kuchengetedza dziviriro kubva kuzvirwere. Kumira kunogona kukuisa panjodzi huru yezvirwere zvinotyisa hupenyu.

Kune autoimmune conditions, chiremba wako anogona kufunga kuderedza kana kumisa kurapwa kana zviratidzo zvako zvikavandudza uye kugara zvakagadzikana. Sarudzo iyi inoda kutariswa zvakanyanya uye kudzikisa zvishoma nezvishoma pane kumisa kamwe kamwe. Usambomira IVIG wega usina kutariswa kwechiremba.

Ndingafamba Here Ndichitora Immune Globulin?

Hongu, unogona kufamba uchigamuchira kurapwa kwe immune globulin, asi zvinoda kuronga pachine nguva. Unozofanira kubatana nemahofisi ekuchengetwa kwehutano kwauri kuenda kana kuronga rwendo rwako zvichienderana nechirongwa chako chekuiswa. Vamwe vanhu vanoronga kugamuchira kurapwa pazvipatara zvekupinza mumamwe maguta.

Pakuenda kunze kwenyika, tora magwaro pamusoro pekurapwa kwako uye mamiriro ako ezvinhu. Funga nezve inishuwarenzi yekufamba inovhara kurapwa kwekurapa, uye gara uine ruzivo rwekukurumidzira rwevashandi vako vehutano. Chiremba wako anogona kupa tsamba inotsanangura chikonzero chako chemushonga uyu.