Chii chinonzi Insulin Degludec: Zvayinoshandiswa, Madosi, Migumisiro Yakaipa uye Zvimwe Zvakawanda

Insulin degludec i insulin inoshanda kwenguva refu iyo inobatsira vanhu vane chirwere cheshuga kudzora mazinga avo eshuga yeropa masikati neusiku. Insulin iyi yakagadzirwa inoshanda kwemaawa anosvika makumi mana nemaviri mushure mejekiseni, zvichiita kuti ive imwe yeiyo insulin inogara kwenguva refu iripo. Yakagadzirirwa kupa kugadzikana, kutonga kweshuga yeropa nguva dzose ine zvishoma zvakanyanya uye makomo kupfuura insulini inoshanda kwenguva pfupi.

Chii chinonzi Insulin Degludec?

Insulin degludec imhando yakagadzirwa nemunhu ye insulin inogadzirwa nemuviri wako. Iyo ndeyeboka remishonga inonzi ultra-long-acting insulins, zvinoreva kuti inoburitswa zvishoma nezvishoma uye zvishoma nezvishoma muropa rako kwemaawa mazhinji. Kusiyana ne insulin yenguva dzose iyo pancreas yako inogadzira zuva rese, mushonga uyu unopa yakagadzikana baseline level ye insulin iyo muviri wako unogona kuvimba nayo.

Mushonga uyu unouya semhinduro yakajeka, isina ruvara yaunojekesa pasi peganda rako uchishandisa chishandiso chepeni. Kana wajekeswa, inogadzira zvidimbu zvidiki pasi peganda rako zvinoburitsa zvishoma nezvishoma insulin muropa rako. Iyi dhizaini yakasiyana inobatsira kupfavisa shuga yeropa uye inoderedza njodzi yezviitiko zvine njodzi zvepasi shuga yeropa, kunyanya usiku.

Chii chinonzi Insulin Degludec chinoshandiswa?

Insulin degludec inorapa ese mhando 1 uye mhando 2 chirwere cheshuga muvanhu vakuru nevana vane gore rimwe chete. Kune vanhu vane mhando 1 chirwere cheshuga, inoshanda seiyo foundation insulin iyo inotsiva izvo pancreas yavo isingachakwanisi kugadzira. Avo vane mhando 2 chirwere cheshuga vanoishandisa kana muviri wavo usingagadziri insulin yakakwana kana kana mamwe mishonga yechirwere cheshuga isingadzore shuga yavo yeropa nemazvo.

Chiremba wako angakupa mushonga uyu kana uri kusangana nekuwanda kwezviitiko zve shuga yakaderera yeropa pamwe chete nemamwe marudzi e insulin anogara kwenguva refu. Zvinonyanya kubatsira vanhu vane hurongwa husina kufanana kana kutadza kuronga kudya kwavo nguva dzose. Kugona kuchinjika kwemushonga kunobvumira kuchinja zvishoma munguva yekudzora jekiseni uku uchiri kuchengetedza kutonga kwakanaka kweshuga yeropa.

Vamwe vanhu vanoshandisawo insulin degludec sechikamu chekurapa kwakabatanidzwa pamwe chete ne insulin inokurumidza kuita yekudya kana mamwe mishonga yechirwere cheshuga. Iyi nzira inobatsira kuvhara zvese zvinodiwa nemuviri wako zve insulin uye iyo yakawedzerwa insulin inodiwa kana iwe uchidya.

Insulin Degludec Inoshanda Sei?

Insulin degludec inoshanda nekutevedzera kugadzirwa kwe insulin kwemuviri wako. Paunoiisa jekiseni, mushonga unogadzira cheni dzakagadzikana pasi peganda rako dzinobvaruka zvishoma nezvishoma uye kuburitsa insulin nekufamba kwenguva. Iyi nzira inogadzira yakatsetseka, inofungidzira insulin level muropa rako inogara kwenguva refu kupfuura mamwe marudzi e insulin.

Mishonga inoonekwa seyakasimba uye yakavimbika insulin sarudzo. Inobatsira maseru ako kutora glucose kubva muropa rako uye inoratidza chiropa chako kuti chideredze kugadzirwa kwe glucose. Kusiyana ne insulin inokurumidza kuita inoshanda nekukurumidza uye inopera nekukurumidza, degludec inopa yakagadzikana background insulin coverage isingakwiri zvakanyanya.

Chinonyanya kuita kuti insulin iyi ive yakakosha ndiyo yayo inowirirana action profile. Nepo mamwe ma insulin anogara kwenguva refu angave aine zvimwe zvakakwira nezvakataurwa mukushanda kwavo, degludec inochengetedza yakati sandara insulin level. Kugadzikana uku kunobatsira kuderedza shuga yeropa uye kunoita kuti manejimendi echirwere cheshuga afungidzike kune vanhu vazhinji.

Ndingatora Sei Insulin Degludec?

Muchinjika insulin degludec kamwe chete pazuva pasi peganda rechidya chako, ruoko rwepamusoro, kana dumbu. Muchinjika unofanira kuenda munyama ine mafuta pasi peganda rako, kwete mumhasuru. Shandura nzvimbo dzako dzekujekesa mukati memunharaunda imwechete kuti udzivise matambudziko eganda uye uve nechokwadi chekuti inotorwa zvakanaka.

Tora mushonga uyu panguva imwe chete zuva rega rega kana zvichibvira, kunyange zvichipa kuchinjika kupfuura mamwe ma insulini. Unogona kuuchinjika uine kana usina chikafu sezvo isina kugadzirirwa kuvhara chikafu. Kana dzimwe nguva uchida kuchinja nguva yako yekujekesa, unogona kuita kudaro chero paine maawa angangoita 8 pakati pemadosi.

Usati wajekesa, rega mushonga usvike tembiricha yemumba kana wakachengetwa mufiriji. Insulin inotonhora inogona kusagadzikana uye inogona kusatorwa zvakanaka. Nguva dzose shandisa tsono itsva yekujekesa kwega kwega uye rasa tsono dzakashandiswa zvakachengeteka mumudziyo we sharps.

Chiremba wako achakutanga padosi chaiyo zvichienderana nezvido zvako zvaunoshandisa insulin uye maitiro eshuga yeropa. Usambofa wakachinja dosi yako usina kutungamirirwa nachiremba, sezvo shanduko dze insulin dzinogona kukanganisa zvakanyanya mazinga eshuga yeropa rako. Chengeta nguva dzako dzekujekesa uye kuverenga glucose yeropa kuti ubatsire timu yako yehutano kuti iite chero shanduko dzinodiwa.

Ndinofanira Kutora Insulin Degludec Kwenguva Yakareba Sei?

Vanhu vazhinji vane chirwere cheshuga vanofanira kutora insulin degludec zvachose sechikamu chechirongwa chavo chekuchengetedza chirwere cheshuga kwenguva refu. Sezvo chirwere cheshuga chiri mamiriro akareba, kudiwa kwemuviri wako kwe rutsigiro rwe insulin kazhinji kunoenderera mberi muhupenyu hwako hwese. Zvisinei, nguva yako chaiyo yekurapa inoenderana nerudzi rwako rwechirwere cheshuga uye kuti muviri wako unopindura sei kumushonga.

Kune vanhu vane chirwere cheshuga che rudzi rwe 1, insulin degludec inowanzoita chikamu chisingachinji chekurapa kwavo. Pancreas yavo haigadziri insulin zvishoma kana kusagadzira zvachose, saka vanoda kutsiva insulin nguva dzose kuti varambe vaine hutano. Kumisa mushonga uyu pasina kutarisirwa kwechiremba kwakakodzera kungaita kuti pave nematambudziko ane njodzi.

Avo vane chirwere cheshuga che rudzi rwe 2 vangave nemitsetse yenguva yakasiyana zvichienderana nekufambira mberi kwechirwere chavo. Vamwe vanhu vangada mushonga uyu kwenguva pfupi vachichinja mararamiro avo, nepo vamwe vachida kwenguva refu sezvo chirwere chavo cheshuga chichiwedzera. Chiremba wako achagara achiongorora kana mushonga uyu uchiri sarudzo yakanakisa yezvido zvako zviri kuchinja.

Kugara uchienda kunoona chiremba kunobatsira kuona kana uchifanira kuenderera mberi, kugadzirisa, kana kuchinja kurapwa kwako kwe insulin. Mukoti wako wehutano achatarisa kutonga kwako shuga yeropa, hutano hwako hwese, uye chero mhedzisiro kuti aite sarudzo dzine ruzivo nezve nguva yekurapa kwako.

Ndezvipi Zvipingamupinyi zve Insulin Degludec?

Semishonga yese, insulin degludec inogona kukonzera mhedzisiro, kunyangwe vanhu vazhinji vachizvitsungirira zvakanaka. Mhedzisiro inowanzoitika uye inonetsa ndiyo shuga yeropa yakaderera (hypoglycemia), iyo inogona kuitika kana ukatora insulin yakawandisa, ukasvetuka chikafu, kana kuita maekisesa akawanda kupfuura zvakajairika usina kugadzirisa muyero wako.

Heano mhedzisiro inonyanya kuziviswa yaungasangana nayo:

• Zviratidzo zve shuga yeropa yakaderera senge kudedera, kutukutira, kuvhiringika, kana kurova kwemoyo nekukurumidza
• Kuita kwenzvimbo yekujekesa senge kutsvuka, kuzvimba, kana kukwenya
• Kuwedzera uremu, izvo zvakajairika nemarapi mazhinji e insulin
• Kutemwa nemusoro, kunyanya kana uchitanga mushonga
• Zvirwere zvepamusoro zvekufema senge zviratidzo zvefuruwenza
• Kuzvimba mumaoko ako, tsoka, kana zvitsitsinho

Izvi zvinowanzoitika zvinowanzoita nani sezvo muviri wako uchigadzirisa kumushonga. Zvisinei, unofanira kukurukura chero zviratidzo zvinoramba zviripo kana zvinonetsa nemukoti wako wehutano.

Mhedzisiro isingawanzoitika asi yakakomba inoda kutariswa kwekurapa nekukasira. Shuga yeropa yakaderera zvakanyanya inogona kukonzera kubatwa, kurasikirwa kwechizvarwa, kana kunyange koma kana ikasiyiwa isina kurapwa. Maitiro ekuita allergic, kunyangwe asingawanzoitiki, anogona kusanganisira kuoma kufema, kuzvimba kwechiso chako kana huro, kana rash yakapararira.

Vamwe vanhu vanokudziridza lipodystrophy, iyo inokonzera shanduko mumafuta emuviri panzvimbo dzekujekesa. Izvi zvinogona kuoneka semapundu, dimples, kana ganda rakakora paunojekesa. Kutenderera nzvimbo dzekujekesa kunobatsira kudzivirira dambudziko iri, uye nzvimbo dzakakanganiswa dzinowanzoita nani nekufamba kwenguva nekutenderera kwenzvimbo kwakakodzera.

Ndiani Asingafaniri Kutora Insulin Degludec?

Insulin degludec haina kukodzera munhu wese ane chirwere cheshuga. Haufaniri kushandisa mushonga uyu kana uine allergic kuinsulin degludec kana chero chimwe chezvinhu zvayo. Vanhu vari kusangana ne diabetic ketoacidosis, matambudziko akakomba apo muviri unogadzira maasidhi ane njodzi, vanoda kurapwa kwakasiyana uye havafaniri kushandisa ma insulins anogara kwenguva refu panguva idzi.

Chiremba wako achanyatsoongorora kana mushonga uyu wakachengeteka kwauri kana uine mamwe mamiriro ehutano. Vanhu vane chirwere chakakomba cheitsvo kana chiropa vanogona kuda kugadzirisa dosi kana mamwe marapirwo. Avo vane nhoroondo yezviitiko zvakakomba, zvinowanzoitika shuga yeropa yakaderera vangangoda kuwedzera kuongororwa kana dzimwe sarudzo dze insulin.

Vakadzi vane pamuviri uye vanoyamwisa vanogona kushandisa insulin degludec, asi vanoda kutariswa kwepedyo kwekurapa. Pamuviri kazhinji inochinja zvinodiwa zve insulin, uye chiremba wako angangoda kugadzirisa dosi rako kana kuchinja mishonga. Vana vari pasi pemakore rimwe havafaniri kushandisa mushonga uyu, sezvo kuchengeteka uye kushanda kwavo zvisina kumiswa neboka rezera iri.

Kana iwe uri kutora mamwe mishonga anogona kukanganisa shuga yeropa, chiremba wako angasarudza dzimwe sarudzo dze insulin kana kukutarisa zvakanyanya. Nguva dzose zivisa mupi wako wehutano nezve mishonga yese, zvinowedzera, uye mamiriro ehutano usati watanga insulin degludec.

Zita reBrand reInsulin Degludec

Insulin degludec inotengeswa pasi pezita rebrand rekuti Tresiba munyika zhinji, kusanganisira United States. Tresiba inouya mumidziyo yepeni yakazadzwa kare inoita kuti jekiseni rive nyore uye riri nyore kupfuura mabhodhoro echinyakare nemajekiseni. Mushonga uyu unowanikwa mumhando mbiri: Tresiba U-100 uye Tresiba U-200.

Iyo U-100 formulation ine 100 units ye insulin pa milliliter, nepo U-200 iine 200 units pa milliliter. Sarudzo yepamusoro inobvumira vanhu vanoda madosi makuru e insulin kuti vatore huwandu hudiki. Zvese zviri zviviri zvinoshanda zvakafanana mumuviri wako, asi kuverenga kwemadosi kunosiyana zvishoma.

Pharmacy yako inogona kutakura mhando dzegeneric dze insulin degludec, kunyangwe izvi zvisingawanzoitiki kupfuura sarudzo dzemazita emhando. Nguva dzose simbisa nemupharmacist wako kuti uri kugamuchira iyo chaiyo formulation uye concentration iyo chiremba wako akanyora.

Zvimwe Zvinhu zveInsulin Degludec

Mamwe ma insulins marefu-anoshanda anogona kushanda sezvimwe zvekuti insulin degludec kana isina kukodzera kwauri. Insulin glargine (Lantus, Basaglar) ndiyo imwe yeanowanzo nyorwa ma insulins marefu-anoshanda anopa 24-awa yekuvhara. Yave iripo kwenguva refu kupfuura degludec uye inogona kuve yakachipa kune vamwe vanhu.

Insulin detemir (Levemir) ndiyo imwe sarudzo yakareba-inoshanda iyo inowanzo gara maawa gumi nemaviri-24. Vamwe vanhu vanoda majekiseni maviri zuva rega rega ne detemir, kusiyana ne degludec's once-daily dosing. Zvisinei, detemir inogona kukonzera kuwedzera uremu kushoma pane mamwe ma insulins marefu-anoshanda.

Heano mamwe mamwe maitiro ayo chiremba wako angatarisa:

• Insulin glargine U-300 (Toujeo) - imhando ye insulin glargine yakanyanya kuwanda, inogara kwenguva refu
• NPH insulin (Humulin N, Novolin N) - insulin yekare, inoshanda pakati nepakati iyo isingadhuri asi inoda kushandiswa kakawanda
• Kurapa ne insulin pump - inopa insulin inokurumidza kushanda nguva dzose zuva rese
• Mishonga yakasanganiswa inosanganisira insulin inoshanda kwenguva refu uye inokurumidza kushanda

Mupi wako wehutano achakubatsira kusarudza imwe nzira yakanakisa zvichienderana nemararamiro ako, maitiro eshuga yeropa, inishuwarenzi, uye zvaunofarira. Sarudzo imwe neimwe ine mabhenefiti akasiyana uye zvinhu zvekufunga izvo zvinokanganisa kuti inoshanda sei kune yako chaiyo mamiriro.

Ko Insulin Degludec iri nani pane Insulin Glargine?

Insulin degludec uye insulin glargine zvose zvakanaka kwazvo insulin inoshanda kwenguva refu, asi vane misiyano yakakosha. Degludec inowanzoita kuti shuga yeropa idzoreke zvakanyanya nekushoma kwezviitiko zve shuga yeropa yakaderera, kunyanya usiku. Inopawo kuchinjika kwakawanda mukuisa nguva, izvo zvinogona kubatsira vanhu vane zvirongwa zvisina kugadzikana.

Zvidzidzo zvinoratidza kuti degludec inogona kuderedza njodzi ye hypoglycemia yakanyanya neanenge 40% ichienzaniswa ne glargine. Kuvandudzwa uku kunonyanya kucherechedzwa panguva yeusiku apo zviitiko zvine njodzi zve shuga yeropa yakaderera zvinogona kusazivikanwa. Iyo ultra-refu nguva ye degludec zvinorevawo mazinga e insulin akagadzikana zuva rese.

Zvisinei, glargine yave iripo kwenguva refu uye inogona kuve yakachipa nekuda kwesarudzo dzakajairika. Vamwe vanhu vanowana yakanaka shuga yeropa kudzora ne glargine uye havafaniri kuchinja mishonga. Inishuwarenzi inovharawo, uye chirongwa chako chinogona kufarira imwe sarudzo pane imwe.

Chiremba wako achafunga nezvezvido zvako zvakakosha, maitiro eshuga yeropa, mararamiro, uye nhoroondo yako yekurapa paachisarudza pakati pemishonga iyi. Hapana imwe iri nani kupfuura imwe, sezvo sarudzo yakanakisa ichienderana nekuti muviri wako unopindura sei uye chii chinoshanda zvakanyanya kune yako yezuva nezuva.

Mibvunzo Inowanzo Bvunzwa Nezve Insulin Degludec

Insulin Degludec Yakachengeteka Here Kune Chirwere Cheitsvo?

Insulin degludec inogona kuva yakachengeteka kune vanhu vane chirwere cheitsvo, asi inoda kutariswa zvakanyanya uye kugadzirisa muyero. Itsvo dzako dzinobatsira kugadzirisa uye kubvisa insulin kubva mumuviri wako, saka kushanda kweitsvo kwakaderera kunogona kukanganisa kuti mushonga unogara kwenguva yakareba sei mumuviri wako. Izvi zvinogona kuwedzera njodzi yako yezviitiko zvepasi shuga yeropa.

Chiremba wako anogona kutanga nemuyero wakaderera uye achatarisa shuga yako yeropa kakawanda kana uine matambudziko eitsvo. Vanogona zvakare kukurudzira kugadzwa kwekutevera-up kakawanda kuti vaone kuti mushonga uri kushanda zvakachengeteka. Vanhu vane chirwere cheitsvo chakakomba kana avo vari pa dialysis vanoda kutariswa zvakanyanya pavanenge vachishandisa chero insulin.

Ndoita Sei Kana Ndikashandisa Insulin Degludec Yakawandisa Netsaona?

Kana ukabaya insulin degludec yakawandisa netsaona, tarisa shuga yako yeropa zvakanyanya uye uve wakagadzirira kurapa zviratidzo zvepasi shuga yeropa. Idya kana kunwa chimwe chinhu chine shuga nekukasira, senge mahwendefa eglucose, muto wemichero, kana soda yakajairika. Usamirira kuti zviratidzo zviite, sezvo kudzivirira kwakachengeteka kupfuura kurapa.

Bata mupi wako wehutano kana kufonera nzvimbo yekudzora chepfu kuti uwane gwara rekugadzirisa overdose. Vanogona kukurudzira chikafu chakati wandei chekudya, kuti ungatarisa sei shuga yako yeropa, kana kuti unoda kutariswa kwekurapa. Chengeta mahwendefa eglucose kana mamwe makabhohaidhireti anokurumidza kuita padyo pese paunobaya insulin.

Kana ukaora mwoyo zvakanyanya kana ukashaya chekuziva, mumwe munhu anofanira kufonera masevhisi ekukurumidzira nekukasira. Kuva nekit yekukurumidzira ye glucagon inogona kuponesa upenyu mumamiriro ezvinhu aya, kunyanya kana uchigara wega kana uine nhoroondo yezviitiko zvakanyanya zve shuga yakaderera yeropa.

Ndingaita Sei Kana Ndakakanganwa Dose ye Insulin Degludec?

Kana ukakanganwa dose yako ye insulin degludec, itore nekukasira paunoyeuka, chero paine maawa angangoita 8 usati watora dose yako inotevera yakarongwa. Kana yava nguva yekutora dose yako inotevera, siya dose yakakanganwa uye uenderere mberi nechirongwa chako chetsika. Usambofa wakatora madosi maviri panguva imwe chete kuti ugadzirise dose yakakanganwa.

Tarisa shuga yako yeropa kakawanda mushure mekukanganwa dose, sezvo mazinga ako anogona kunge akakwira kupfuura zvakajairika. Unogona kuda kugadzirisa zvekudya zvako kana mwero wekuita kuti ugadzirise insulin yakakanganwa. Bata chiremba wako kana shuga yako yeropa ichiramba yakakwira kana usina chokwadi chekuti ungaita sei mamiriro acho ezvinhu.

Kuti udzivise madosi akakanganwa, funga nezvekuseta maalarm efoni kana kushandisa chirongwa chemapiritsi chine zvinhu zvekuyeuchidza. Vamwe vanhu vanoona zvichibatsira kujekesa insulin yavo panguva imwe chete neimwe chiitiko chezuva nezuva, sekukwesha mazino avo kana kudya kwemangwanani.

Ndingamira Rini Kutora Insulin Degludec?

Unofanira kungomira kutora insulin degludec pasi pekutariswa kwakananga kwechiremba wako. Kune vanhu vane chirwere cheshuga che rudzi rwekutanga, kumisa insulin kunogona kuva kunotyisa upenyu uye kutungamirira ku diabetic ketoacidosis mukati meawa kana mazuva. Avo vane chirwere cheshuga che rudzi rwechipiri vangangokwanisa kumisa insulin kana kutonga kwavo shuga yeropa kuchivandudza zvakanyanya kuburikidza nedzimwe nzira.

Chiremba wako angangofunga kumisa kana kuderedza insulin yako degludec kana ukarasikirwa nehuremu hwakawanda, kuwedzera chiitiko chako chemuviri, kana kutanga mamwe mishonga yeshuga inovandudza kunzwisiswa kwemuviri wako kune insulin. Zvisinei, shanduko idzi dzinoda kutariswa zvakanyanya uye kugadzirisa zvishoma nezvishoma panzvimbo yekumisa kamwe kamwe.

Vamwe vanhu vane chirwere cheshuga che mhando 2 vanogona kubva pa insulin kwenguva pfupi, asi vazhinji vanozopedzisira vachifanira kuitangazve sezvo mamiriro avo achienderera mberi. Kutevera nguva dzose kwekurapa kunobatsira kuona nzira yakanakisa yenguva refu yemamiriro ako chaiwo uye zvinangwa zveutano.

Ndingafamba ne Insulin Degludec here?

Hongu, unogona kufamba ne insulin degludec, asi zvinoda kuronga nekugadzirira. Nguva dzose takura insulin yako mumutoro wako wekufamba kana uchibhururuka, sezvo nzvimbo dzekutakura zvinhu dzinogona kuita chando uye kukuvadza mushonga. Uya netsamba kubva kuna chiremba wako ichitsanangura kudiwa kwako kwe insulin uye zvekupa majekiseni kubatsira nekuchengetedzwa kwendege.

Paka insulin yakawanda uye zvekupa kana paine kunonoka kana kurasikirwa nemutoro. Funga kuuya nechitutu chidiki kana kesi ine insulated kudzivirira mushonga wako kubva kutembiricha yakanyanyisa. Insulin degludec inogona kuchengetwa patembiricha yemumba kwemavhiki masere kana yavhurwa, izvo zvinoita kuti kufamba kuve nyore kupfuura mamwe marudzi e insulin.

Tsvaga nzvimbo yekuenda nguva zone uye uronge maitiro ekugadzirisa purogiramu yako yekujekiseni kana zvichidikanwa. Kwefamba kwenguva refu kupfuura mazuva mashoma, ungangoda kushandura zvishoma nezvishoma nguva yako yekujekiseni kuti ienderane nehurongwa hwako hutsva. Mupi wako wehutano anogona kukubatsira kugadzira chirongwa chekufamba chinochengetedza kutonga kwakanaka kweshuga yeropa panguva yerwendo rwako.