Chii chinonzi NPH Insulin: Zvazvinoshandiswa, Madosi, Migumisiro Yakaipa uye Zvimwe

NPH insulin imhando ye insulin inoshanda kwenguva refu iyo inobatsira vanhu vane chirwere cheshuga kudzora mazinga avo eshuga yeropa zuva rese. Inonzi "intermediate-acting" nekuti inoshanda kwemaawa anenge 12-18, ichipa kudzora glucose kwakagadzikana pakati pemadyiro uye husiku hwese.

Rudzi urwu rwe insulin runowana zita rayo kubva kuNeutral Protamine Hagedorn, mushure mewanani akaiumba. Chikamu che "isophane" chinoreva kuti insulin inogadzirwa sei neprotamine kuti ideredze kunyudzwa kwayo mumuviri wako.

Chii chinonzi NPH Insulin chinoshandiswa?

NPH insulin inonyanya kushandiswa kurapa ese ari maviri mhando 1 uye mhando 2 chirwere cheshuga kana muviri wako uchida rubatsiro rwekudzora mazinga eshuga yeropa. Inoshanda se insulin yekumashure iyo inotevedzera izvo pancreas yako yaizogadzira zuva rese.

Vanhu vane mhando 1 chirwere cheshuga vanovimba neNPH insulin nekuti miviri yavo haigone kugadzira insulin zvachose. Kune avo vane mhando 2 chirwere cheshuga, NPH insulin inova inodiwa kana mamwe mishonga yakaita semapiritsi asina kukwana kuchengetedza shuga yeropa mumwero wakanaka.

Chiremba wako angangokurudzirawo NPH insulin kana uri kubata chirwere cheshuga chegestational panguva yekuzvitakura. Izvi zvinoitika kana mahomoni ekuzvitakura achiita kuti muviri wako ushandise insulin nemazvo.

NPH Insulin inoshanda sei?

NPH insulin inoshanda nekubatsira maseru ako kutora glucose kubva mumutsipa wako weropa, sekungaita insulin yechisikigo. Inoonekwa se insulin yesimba repakati iyo inopa kugadzikana, kuenderana kudzora shuga yeropa pane kugadzirisa nekukurumidza.

Iyo protamine muNPH insulin inoshanda semuchina wekuburitsa nguva. Paunoiisa pasi peganda rako, iyo protamine inonyungudika zvishoma nezvishoma, ichiburitsa insulin zvishoma nezvishoma mumutsipa wako weropa kwemaawa 12-18.

Kusunungurwa kunononoka uku kunoita kuti insulin yeNPH ive yakanaka zvikuru pakudzivirira kuwedzera kweshuga yeropa pakati pemadyiro uye panguva yekurara. Inowanzo kutanga kushanda mukati me1-2 maawa, inosvika pakakwirira pakati pe4-6 maawa, uye inoenderera mberi ichishanda kwemaawa anosvika gumi nemasere.

Ndinofanira Kutora Sei Insulin yeNPH?

Insulin yeNPH inopiwa sejojo pasi peganda, kazhinji muzvitsitsinho zvako, ruoko, kana dumbu. Chiremba wako achakudzidzisa nzira yekujova yakakodzera uye kukubatsira kusarudza nzvimbo dzakanakisisa dzekujova.

Iwe unowanzo tora insulin yeNPH kamwe kana kaviri pazuva, kazhinji pamberi pemangwanani uye kudya kwemanheru. Vamwe vanhu vanoiita chete panguva yekurara kudzora mazinga eshuga yeropa husiku.

Heano mamwe matanho akakosha ekutevera paunenge uchitora insulin yeNPH:

• Nyatsozunguza bhodhoro pakati pezvanza zvako kuti usanganise insulin - usambofa wakazunguzira zvine simba
• Chenesa nzvimbo yekujova nealcohol swab
• Chinja nzvimbo dzekujova kudzivirira matambudziko eganda
• Chengeta mabhodhoro asina kuvhurwa mufiriji
• Chengeta bhodhoro rauri kushandisa parizvino patembiricha yemumba

Kusiyana nemimwe mishonga, insulin yeNPH haifaniri kutorwa nechikafu, asi nguva nemadyiro inogona kubatsira kudzivirira shuga yeropa yakaderera. Mupi wako wehutano achakupa mirairo chaiyo zvichienderana nehurongwa hwako hwekudya.

Ndinofanira Kutora Insulin yeNPH Kwenguva Yakareba Sei?

Vanhu vazhinji vane chirwere cheshuga che1 vachada insulin yeNPH kwehupenyu hwese, sezvo miviri yavo isingakwanise kugadzira insulin zvakasikwa. Kureba kunoenderana zvachose nemamiriro ako ega uye kuti muviri wako unopindura sei kurapwa.

Kune chirwere cheshuga che2, unogona kuda insulin yeNPH kwenguva refu kana kwenguva pfupi, zvichienderana nezvinhu zvakaita sekudzora kweshuga yeropa, mamwe mishonga, uye shanduko yehupenyu. Vamwe vanhu vanogona kuzopedzisira vaderedza kana kumisa insulin kana vakaita kuvandudzwa kukuru mukudya kwavo uye tsika dzekurovedza muviri.

Chiremba wako achagara achiongorora mazinga eshuga yeropa rako uye achigadzirisa chirongwa chako chekurapa sezvinodiwa. Usambomira kutora insulin yeNPH usina kubvunza mupi wako wehutano, sezvo izvi zvingaita kuti shuga yeropa iwedzere zvakanyanya.

Ndezvipi Zvipingamupinyi zveNPH Insulin?

Chipingamupinyi chinowanzoitika cheNPH insulin ishuga yeropa yakaderera (hypoglycemia), iyo inogona kuitika kana iwe ukatora insulin yakawanda, ukasvetuka chikafu, kana kurovedza muviri zvakanyanya kupfuura zvakajairika. Zviratidzo zvinosanganisira kudedera, kutukwa, kuvhiringidzika, uye nzara.

Ngatitarisei zvipingamupinyi zvaungasangana nazvo, tichitanga neizvo zvinowanzoitika:

• Zvikamu zveshuga yeropa yakaderera ine zviratidzo zvakaita sedzungu, kukurumidza kwemoyo, kana kusagadzikana
• Kuita kwenzvimbo yekujekesa senge kutsvuka, kuzvimba, kana kurwadziwa kudiki
• Kuwedzera uremu sezvo muviri wako unotanga kushandisa glucose zvakanyanya
• Kuchinja kweganda panzvimbo dzekujekesa kana iwe usingatenderedze nzvimbo

Zvisingawanzoitiki asi zvakanyanya zvipingamupinyi zvinosanganisira shuga yeropa yakaderera yakanyanya inoda kurapwa kwemamiriro ezvinhu, uye mhinduro dzisingawanzoitiki dzekurwara dzine zviratidzo zvakaita sekufema kwakaoma, kuzvimba, kana rash yakapararira.

Vanhu vazhinji vanotsungirira NPH insulin zvakanaka, uye zvipingamupinyi zvinowanzoita nani sezvo muviri wako uchigadzirisa mushonga. Nguva dzose chengeta mapiritsi eglucose anokurumidza kana muto padhuze kuti urape shuga yeropa yakaderera nekukurumidza.

Ndiani Asingafaniri Kutora NPH Insulin?

Vanhu vashoma vanogona kutora NPH insulin, asi mamiriro akati wandei anoda kungwarira kwakawanda kana dzimwe nzira dzekurapa. Vanhu vane zvikamu zvakanyanya, zvinowanzoitika zveshuga yeropa yakaderera vangangoda imwe nzira ye insulin.

Chiremba wako achanyatsoongorora kana NPH insulin yakakunakira kana uine mamiriro ehutano akati wandei:

• Zvirwere zveitsvo, izvo zvinogona kukanganisa nzira iyo muviri wako unogadzirisa insulin
• Matambudziko echiropa anogona kuchinja zvinodiwa zve insulin
• Mamiriro emoyo anogona kuwedzerwa nezviitiko zve shuga yakaderera yeropa
• Nhoroondo yezvinhu zvakanyanya kuipa kune insulin kana zvinhu zvayo
• Kudya zvirwere zvinoita kuti nguva yekudya isafanirwe

Kuzvitakura nekuyamwisa hazvirevi kuti haugone kushandisa NPH insulin, asi chiremba wako anogona kugadzirisa mushonga wako. Vana vanogona kushandisa NPH insulin zvakachengeteka, kunyangwe vachigona kuda mamwe mafomu kana hurongwa hwekuisa mushonga.

Mazita eBrand eNPH Insulin

NPH insulin inowanikwa pasi pemazita akati wandei ebrand, neHumulin N naNovolin N ndiyo mhando dzakanyanya kunyorerwa muUnited States. Zvose zvine chinhu chimwe chete chinoshanda asi zvinogona kuva nemusiyano mudiki muzvinhu zvisingashandi.

Humulin N inogadzirwa naEli Lilly, nepo Novolin N ichibva kuNovo Nordisk. Mushonga wako unogona kuva neimwe kana ese mabhurendi, uye anowanzo shandurwa nekubvumidzwa kwechiremba wako.

Mamwe mapurani einishuwarenzi anogona kusarudza imwe brand pane imwe, saka zvakakosha kutarisa nemupi wako weinishuwarenzi nezvekuvharwa. Mabhurendi ese aripo mumavhiri uye mapeni akazadzwa kare kuti zvive nyore kujekiseni.

Zvimwe zvingashandiswa panzvimbo peNPH Insulin

Mamwe ma insulin ekati pakati nepakati uye akareba anogona kushanda sezvimwe zvingashandiswa panzvimbo peNPH insulin, zvichienderana nezvaunoda. Insulin glargine (Lantus) uye insulin detemir (Levemir) ndiyo mhinduro dzenguva refu dzinopa mazuva makumi maviri nemana ekufukidza.

Izvi zvitsva zvingangopa kutonga kweshuga yeropa kunofungidzirwa zvakanyanya nekuda kwengozi shoma yezviitiko zve shuga yakaderera yeropa husiku. Zvisinei, vanowanzo dhura kupfuura NPH insulin.

Chiremba wako anogonawo kufunga nezvekusanganiswa kwe insulin iyo inosanganisa NPH ne insulin inokurumidza kuita mujekiseni rimwe. Izvi zvinosanganisira 70/30 insulin (70% NPH, 30% yakajairika) kana misanganiswa yakafanana inogona kurerutsa hurongwa hwako hwekuisa mushonga.

Ko Insulin yeNPH iri nani pane Insulin Glargine?

Insulin yeNPH ne insulin glargine (Lantus) zvinopa zvese kudzora shuga yeropa kwenguva refu, asi zvinoshanda zvakasiyana uye zvine zvakanakira zvakasiyana. Hapana imwe iri yese 'iri nani' - sarudzo inoenderana nemararamiro ako, maitiro eshuga yeropa, uye zvinangwa zvekurapa.

Insulin yeNPH inodhura zvishoma zvakanyanya pane insulin glargine uye yanga ichishandiswa zvakachengeteka kwemakumi emakore. Inoshanda zvakanaka kune vanhu vazhinji uye inopa kudzora kwakavimbika kweshuga yeropa kana ichishandiswa nguva dzose.

Insulin glargine inopa kutora kunofungidzirwa zvakanyanya uye inogara padyo nemaawa makumi maviri nemana, izvo zvinogona kureva kushanduka kushoma kweshuga yeropa. Iyo zvakare ine njodzi shoma yekukonzera zviitiko zvepasi pehusiku shuga yeropa.

Chiremba wako achakubatsira kuyera zvinhu zvakaita semutengo, nyore, uye maitiro ekudzora shuga yeropa kuti uone kuti ndeipi insulin inoshanda zvakanyanya mumamiriro ako ezvinhu.

Mibvunzo Inowanzo Bvunzwa Nezve Insulin yeNPH

Ko Insulin yeNPH yakachengeteka here kuvarwere vane chirwere cheitsvo?

Insulin yeNPH inogona kushandiswa zvakachengeteka muvanhu vane chirwere cheitsvo, asi inoda kunyatso tarisa uye kugadzirisa muyero. Itsvo dzako dzinobatsira kuparadza insulin, saka matambudziko eitsvo anogona kuita kuti insulin igare muchirongwa chako kwenguva refu.

Izvi zvinoreva kuti unogona kuda madosi akaderera e insulin yeNPH kana uine chirwere cheitsvo. Chiremba wako achatarisa kushanda kweitsvo yako uye mazinga eshuga yeropa zvakanyanya kudzivirira zviitiko zvine njodzi zvepasi shuga yeropa.

Ndoita sei kana ndikashandisa insulin yeNPH yakawandisa netsaona?

Kana ukabaya insulin yeNPH yakawandisa netsaona, usavhunduka, asi tora matanho nekukasira kudzivirira shuga yeropa yakanyanya. Idya kana kunwa chimwe chinhu chine makabhohaidhireti anokurumidza kuita sepiritsi reglucose, muto wemichero, kana soda yenguva dzose.

Tarisa shuga yako yeropa zvakanyanya kwemaawa gumi nemaviri-18 anotevera sezvo insulin yeNPH ichishanda kwenguva yakareba. Bata chiremba wako kana mupi wehutano kuti ukurukure kugadzirisa muyero wako unotevera uye kuti uwane gwara rekugadzirisa mamiriro acho ezvinhu.

Tsvaga rubatsiro rwekurumidza rwekurapa kana uine zviratidzo zvakanyanya zvakaita sekusagadzikana, kurasikirwa nekuziva, kana kubatwa. Chengeta zvekushandisa zvekukurumidzira zveglucagon kana chiremba wako achikurudzira.

Ndingaita Sei Kana Ndakakanganwa Dose yeNPH Insulin?

Kana iwe ukakanganwa dose yeNPH insulin, itore nekukasira sezvaunorangarira, kunze kwekunge yave nguva yechikamu chako chinotevera. Usambofa wakawedzera doses kuti ugadzirise imwe yakarasika.

Tarisa shuga yako yeropa kakawanda mushure mekusakanganwa dose, sezvo mazinga ako anogona kunge akakwira kupfuura zvakajairika. Unogona kuda kugadzirisa nguva yako yekudya kana kubata chiremba wako kuti akutungamirire.

Kana iwe uchikanganwa doses kazhinji, funga nezvekuseta maalarm efoni kana kushandisa chirongwa chemapiritsi kuti zvikubatsire kurangarira. Nguva dzose dzakakosha kuti NPH insulin ishande nemazvo.

Ndingamira Rini Kutora NPH Insulin?

Vanhu vane chirwere cheshuga chetype 1 vanowanzo shandisa insulin muhupenyu hwavo nekuti miviri yavo haigone kuigadzira zvakasikwa. Zvisinei, avo vane chirwere cheshuga chetype 2 vanogona kuderedza kana kumisa insulin kana kutonga kwavo shuga yeropa kuchivandudza zvakanyanya.

Chiremba wako achaongorora kana iwe uchikwanisa kumisa NPH insulin zvichienderana nemazinga ako eshuga yeropa, hutano hwako hwese, uye mamwe mishonga yeshuga. Sarudzo iyi haifaniri kuitwa pasina kutariswa kwekurapa.

Vamwe vanhu vanogona kuderedza zvinodiwa zvavo zve insulin kuburikidza nekurasikirwa uremu, kudya kwakavandudzwa, kurovedza muviri nguva dzose, kana mamwe mishonga yeshuga. Chikwata chako chehutano chichashanda newe kuti uwane chirongwa chakanakisa chekurapa kwenguva refu.

Ndingasanganisa NPH Insulin neimwe Insulin here?

NPH insulin inogona kusanganiswa ne insulin yakajairika mune imwechete syringe, asi haifaniri kusanganiswa ne insulin inokurumidza-kuita se insulin lispro kana aspart. Nguva dzose tevera mirairo chaiyo yechiremba wako nezvekusanganisa insulins.

Paunosanganisa insulins, tanga watora insulin yakajeka yekutanga, wobva watora insulin yeNPH ine makore. Izvi zvinodzivirira kusvibiswa uye zvinovimbisa kuyera kwakaringana kwemarudzi ese ari maviri.

Mishonga ye insulin yakavhenganiswa inowanika kana chiremba wako akasarudza kuti unoda zvese NPH ne regular insulin. Izvi zvinobvisa kudiwa kwekusanganisa uye zvinogona kurerutsa maitiro ako ekujova.