Chii chinonzi NPH uye Regular Insulin: Zvinoshandiswa, Dosage, Migumisiro uye Zvimwe

NPH uye regular insulin imishonga yakasanganiswa inobatsira vanhu vane chirwere cheshuga kudzora mazinga avo eshuga yeropa zuva rese. Musanganiswa uyu une mhando mbiri dzakasiyana dze insulin dzinotsvaga pamitengo yakasiyana - regular insulin inoshanda nekukurumidza apo NPH insulin inopa nguva refu yekuvhara.

Funga nezve musanganiswa uyu semaitiro echikwata ekudzora shuga yeropa. Iyo regular insulin inobata kukwira kweshuga yeropa mushure mekudya, nepo iyo NPH insulin inoshanda zvakatsiga kumashure kuchengetedza mazinga akagadzikana pakati pekudya uye husiku.

Chii chinonzi NPH uye Regular Insulin?

NPH uye regular insulin imusanganiswa wakagadzirirwa we mhando mbiri dze insulin dzakagadzirirwa kurerutsa manejimendi echirwere cheshuga. NPH inomirira Neutral Protamine Hagedorn, iyo iri pakati-inoshanda insulin, nepo regular insulin iri pfupi-inoshanda fomu.

Iyi mishonga yakasanganiswa inouya semvura ine makore yaunojekesa pasi peganda rako. Makore anobva kuNPH insulin, iyo ine mapuroteni anoderera kunwa kwayo. Kana yakasanganiswa pamwe chete, aya ma insulins maviri anopa ese ari maviri nekukurumidza uye akawedzera kudzora shuga yeropa mune imwe jekiseni.

Kazhinji, iwe unowana musanganiswa uyu mu70/30 chiyero, zvinoreva 70% NPH insulin uye 30% regular insulin. Mamwe mafomu anouyawo mumatanho e50/50, zvichienderana nezvako zvaunoda.

Chii chinonzi NPH uye Regular Insulin Inoshandiswa Kuti?

Iyi insulin musanganiswa inonyanya kushandiswa kurapa mhando 1 uye mhando 2 chirwere cheshuga kana muviri wako usingagadziri insulin yakakwana kana usingakwanise kuishandisa nemazvo. Zvinobatsira zvikuru kune vanhu vanoda zvese zvekudya uye kumashure kwe insulin kuvhara.

Chiremba wako angakupa mushonga uyu kana uchitora majekiseni maviri e insulin akasiyana uye uchida kuita kuti zvive nyore. Zvakare zvinowanzo shandiswa kana uchida insulin inogara iripo zuva rese asi usingade kuoma kwemajekiseni akawanda.

Vamwe vanhu vane chirwere cheshuga che mhando 2 vanoshandisa musanganiswa uyu kana mamwe mishonga yakaita se metformin kana sulfonylureas isingape kutonga kwakakwana kweshuga yeropa. Zvakare inogona kunyorerwa panguva yekuzvitakura ye gestational diabetes kana kudya uye kurovedza muviri zvisina kukwana.

Ndeipi nzira inoshanda NPH ne Regular Insulin?

Musanganiswa uyu unoshanda nekutsiva insulin iyo muviri wako unofanirwa kugadzira pachisikigo. Chikamu che insulin ye regular chinotanga kushanda mukati memaminitsi makumi matatu ekujekesa uye chinokwira pakati pe2-4 maawa, zvichiita kuti zvikwanise kudzora shuga yeropa mushure mekudya.

Chikamu che insulin ye NPH chine kutanga kwakanyanya, kutanga kushanda mukati me1-2 maawa uye ichigara kusvika kumaawa makumi maviri nemana. Izvi zvinopa insulin yekumashure iyo muviri wako unoda pakati pekudya uye paunenge uchivata.

Pamwe chete, ma insulins aya anobatsira kufambisa glucose kubva mumutsipa wako wemagazi kuenda kumasero ako, kwaanogona kushandiswa kuwana simba. Musanganiswa uyu unoonekwa seune simba zvine mwero, uchipa kutonga kwakavimbika kweshuga yeropa kune vanhu vazhinji vane chirwere cheshuga kana ichishandiswa sezvakanyorwa.

Ndingatora sei NPH ne Regular Insulin?

Iwe uchajekesa insulin iyi pasi peganda rechidya chako, ruoko rwepamusoro, kana dumbu uchishandisa sirinji kana peni ye insulin. Chiremba wako achakuratidza nzira yekujekesa yakakodzera uye kukubatsira kusarudza nzvimbo dzakanakisa dzekujekesa.

Usati wajekesa yega yega, unozofanirwa kutenderedza zvinyoro nyoro vial kana peni pakati pezvanza zvako kuti usanganise insulin zvakakwana. Mvura inofanira kutaridzika yakafukidzwa zvakaenzana pasina chero mapundu kana makristasi. Usambofa wakazunza vial zvine simba, sezvo izvi zvinogona kukuvadza insulin.

Nguva yakakosha nekubatanidzwa uku. Vanhu vazhinji vanoisa jekiseni maminitsi makumi matatu vasati vadya mangwanani nemanedhero kuti insulin yenguva dzose itange kushanda ropa risati rakura nekuda kwekudya. Unofanira kudya chikafu chako chakarongwa mukati memaminitsi makumi matatu kusvika makumi matanhatu mushure mejekiseni kudzivirira shuga yakaderera yeropa.

Chinjana nzvimbo dzekuisa jekiseni kudzivirira matambudziko eganda senge mapundu kana mapundu. Chengeta chirongwa chekuchinjana uye dzivisa kuisa jekiseni panzvimbo imwechete kakawanda. Kuchenesa nzvimbo dzekuisa jekiseni nedoro hazvidiwi kunze kwekunge chiremba wako achikurudzira zvakananga.

Ndinofanira Kutora NPH neRegular Insulin Kwenguva Yakareba Sei?

Vanhu vazhinji vane chirwere cheshuga type 1 vanoda kurapwa kweinsulin kwehupenyu hwese, sezvo miviri yavo isingakwanise kugadzira insulin zvakasikwa. Kubatanidzwa uku kunogona kuva mhinduro yenguva refu chero bedzi ichiramba ichipa kutonga kwakanaka kweshuga yeropa.

Kune chirwere cheshuga type 2, nguva inoenderana nekuti mamiriro ako anofambira sei uye kuti dzimwe nzira dzekurapa dzinoshanda sei. Vamwe vanhu vanogona kupedzisira vachichinjira kumhando dzakasiyana dzeinsulin kana kuwedzera mamwe mishonga kurongwa kwavo kwekurapa.

Chiremba wako achatarisa nguva dzose mazinga eshuga yeropa rako uye achigadzirisa kurapwa kwako sezvinodiwa. Usambomira kutora insulin pasina kutariswa kwechiremba, sezvo izvi zvinogona kukonzera matambudziko ane njodzi. Kunyangwe iwe uchinzwa zvakanaka, kurapwa kweinsulin nguva dzose kwakakosha kudzivirira matambudziko enguva refu echirwere cheshuga.

Ndezvipi Zvakaipa zveNPH neRegular Insulin?

Semishonga yese, NPH ne regular insulin zvinogona kukonzera mhedzisiro, kunyangwe vanhu vazhinji vachizvitsungirira zvakanaka. Kunzwisisa zvekutarisira kunogona kukubatsira kubata chero nyaya dzinomuka uye kuziva nguva yekubata chiremba wako.

Mhedzisiro yakajairika ndiyo shuga yakaderera yeropa (hypoglycemia), iyo inogona kuitika kana iwe ukatora insulin yakawandisa, ukasvetuka zvikafu, kana kurovedza muviri kupfuura zvakajairwa. Zviratidzo zvekutanga zvinosanganisira kutukwa, kudedera, nzara, dzungu, uye kuvhiringidzika.

Heano mhedzisiro inonyanya kuzivikanwa yaungasangana nayo:

• Kuderera kweshuga yeropa, kunyanya kana kudya kwemanheru kwakanonoka
• Kuwedzera uremu sezvo muviri wako uchichengeta glucose zvakanyanya
• Kuita kwenzvimbo yekujova senge kutsvuka, kuzvimba, kana kukwenya
• Kuchinja kweganda panzvimbo dzekujova, kusanganisira bundu kana dents
• Kusaona zvakanaka kwenguva pfupi sezvo mazinga eshuga yeropa achigadzikana

Izvi zvinowanzoitika zvinowanzoita nani sezvo muviri wako uchigadzirisa mushonga uye sezvo iwe uchigadzirisa kuyera kwako uye nguva.

Kunyangwe zvisingawanzoitiki, vamwe vanhu vanogona kusangana nemhedzisiro yakakomba inoda kutariswa kwekurapa nekukurumidza. Izvi zviitiko hazviwanzoitiki asi zvakakosha kuziva:

• Hypoglycemia yakakomba nekusanganisa, kubatwa, kana kurasikirwa nekuziva
• Allergic reactions ine rash, kuoma kufema, kana kuzvimba
• Zvirwere zvenguva dzose zveganda panzvimbo dzekujova
• Kuchengetwa kwemvura kusingaite kana kuzvimba mumaoko netsoka

Kana iwe ukaona chero ipi zvayo yemhedzisiro yakakomba iyi, taura nemupi wako wehutano nekukurumidza kana kutsvaga kutarisirwa kwekurapa nekukurumidza.

Ndiani Asingafaniri Kutora NPH uye Regular Insulin?

Vanhu vashoma vane chirwere cheshuga havagone kutora iyi insulin musanganiswa, asi mamiriro akati wandei anoda kungwarira kwakakosha kana dzimwe nzira dzekurapa. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa usati wanyora mushonga uyu.

Haufanire kushandisa iyi insulin kana iwe uchichinjana shuga yeropa yakaderera kana kana iwe uchiziva allergy kune chero zvinosanganiswa mukuumbwa. Vamwe vanhu vanogona kuva neallergy kune protamine muNPH insulin, iyo inoda imwe mhando yeinsulin.

Mamiriro akati wandei ekurapa anoda kunyatso tarisa uye zvinogoneka kugadzirisa dose kana uchishandisa iyi insulin musanganiswa:

• Zvirwere zveitsvo, izvo zvinogona kukanganisa mashandiro emuviri wako e insulin
• Zvirwere zvechiropa, izvo zvinogona kuchinja zvaunoda insulin
• Matambudziko ethyroid, izvo zvinogona kukanganisa kutonga kweshuga yeropa
• Kukundikana kwemoyo, izvo zvinogona kukanganisa kuyerera kwemvura mumuviri
• Zvirwere zvakakomba kana kurwara, izvo zvinowanzo wedzera zvinodiwa zve insulin

Chiremba wako achashanda newe kuti aone kana iyi musanganiswa we insulin yakachengeteka uye yakakodzera mamiriro ako chaiwo.

Mazita eBrand eNPH uye Regular Insulin

Iyi musanganiswa we insulin inowanikwa pasi pemazita akati wandei ebrand, nemugadziri wega wega achipa mafomula akasiyana zvishoma uye nzira dzekuendesa. Mazita akajairika ebrand anosanganisira Humulin 70/30 uye Novolin 70/30.

Humulin 70/30 inogadzirwa naEli Lilly uye inouya semabhodhoro e syringes uye mapeni akazadzwa. Novolin 70/30 inogadzirwa naNovo Nordisk uye inowanikwawo mumabhodhoro uye peni mafomati.

Mamwe mafomula matsva anoshandisa insulin analogs panzvimbo ye regular human insulin, senge Humalog Mix 75/25 kana NovoLog Mix 70/30. Izvi zvinoshanda zvakafanana asi zvinogona kuve nenguva dzakasiyana zvishoma. Nguva dzose shandisa chaiyo brand uye mhando iyo chiremba wako anoraira, sezvo kuchinja pakati pemhando kunoda kutariswa kwechiremba.

NPH uye Regular Insulin Zvimwe Zvingasarudzwa

Zvimwe zvingasarudzwa zviripo kana NPH uye regular insulin isingashande zvakanaka kune mararamiro ako kana zvaunoda zvekurapa. Kurapa kwemazuva ano kwe insulin kunopa sarudzo dzakawanda dzekufananidza nguva dzakasiyana uye zvaunofarira.

Long-acting insulin analogs senge insulin glargine (Lantus) kana insulin detemir (Levemir) yakasanganiswa ne rapid-acting mealtime insulins inopa nguva yakawanda inochinjika. Iyi nzira, inonzi basal-bolus therapy, inokutendera kuti uchinje madosi zvichienderana nekudya kwako chaiko uye mazinga ekuita.

Dzimwe nzira dzakavhenganiswa dzinosanganisira insulin lispro mix (Humalog Mix) uye insulin aspart mix (NovoLog Mix), izvo zvinoshandisa rapid-acting analogs panzvimbo ye regular insulin. Mhando idzi dzinoshanda nekukurumidza uye dzinogona kukonzera kushoma kwemazinga e shuga yakaderera pakati pemadyiro.

Kune vanhu vane chirwere cheshuga che mhando 2, mishonga isiri ye insulin yakaita se GLP-1 agonists kana SGLT-2 inhibitors inogona kunge iri dzimwe nzira dzakakodzera kana zvinowedzerwa kune insulin therapy. Chiremba wako achakubatsira kuongorora sarudzo idzi zvichibva pazvido zvako zvakananga.

Ko NPH uye Regular Insulin Zviri Nani Kudarika Lantus?

NPH uye regular insulin combination uye Lantus (insulin glargine) zvinoshanda zvinangwa zvakasiyana mukutarisira chirwere cheshuga, saka "zviri nani" zvinoenderana nezvido zvako uye mararamiro ako. Imwe neimwe ine zvakanakira zvakasiyana uye zvinhu zvekufunga nezvazvo.

Iyo NPH uye regular combination inopa zvese mealtime uye background insulin coverage muzvirinani majekiseni, izvo vamwe vanhu vanowana zviri nyore. Zvakare kazhinji hazvina kudhura kudarika itsva insulin analogs seLantus.

Lantus inopa yakawanda inoenderana, peakless background insulin coverage kwemaawa makumi maviri nemana, izvo zvinogona kuderedza njodzi yekuderera kweshuga yeropa. Zvisinei, iwe uchada yakaparadzana rapid-acting insulin yezvokudya, zvinoreva majekiseni akawanda zuva rese.

Chiremba wako achafunga nezvezvinhu zvakaita semaitiro ako eshuga yeropa, mararamiro, nguva yekudya, uye inishuwarenzi paanokurudzira iyo yakanakisa insulin regimen kwauri. Vamwe vanhu vanoita zviri nani nekufanotaura nguva ye premixed insulin, nepo vamwe vachisarudza kuchinjika kweakaparadzana long-acting uye rapid-acting insulins.

Mibvunzo Inowanzo Bvunzwa Nezve NPH uye Regular Insulin

Ko NPH uye Regular Insulin Zvakachengeteka Here Kune Chirwere Cheitsvo?

Hongu, NPH uye regular insulin inowanzo chengeteka kune vanhu vane chirwere cheitsvo, asi iwe uchada kuongorora pedyo uye zvinogoneka dose adjustments. Itsvo dzako dzinobatsira kuparadza insulin, saka matambudziko eitsvo anogona kuita kuti insulin igare muchirongwa chako kwenguva refu.

Izvi zvinoreva kuti ungada mishonga yakaderera kudzivirira zviitiko zve shuga yakaderera muropa. Chiremba wako achatarisa kushanda kwematsvo ako nguva dzose uye achagadzirisa mishonga yako ye insulin sezvinodiwa. Vanogona zvakare kukurudzira kuyedzwa kweshuga yeropa kakawanda kuti vave nechokwadi chekuti mazinga ako anoramba ari munzvimbo yakachengeteka.

Ndoita Sei Kana Ndikashandisa NPH yakawandisa uye Regular Insulin netsaona?

Kana ukabaya insulin yakawandisa netsaona, usavhunduka, asi ita nekukurumidza kudzivirira shuga yakaderera yeropa inotyisa. Idya kana kunwa chimwe chinhu chine makabhohaidhireti anokurumidza kushanda nekukasira, sekunge mapiritsi e glucose, muto wemichero, kana soda yakajairika.

Tarisa shuga yako yeropa zvakanyanya kwemaawa mashoma anotevera, sezvo insulin icharamba ichishanda. Chengeta makabhohaidhireti anokurumidza kushanda pedyo uye idya chikafu che nguva dzose sezvakatarwa. Bata chiremba wako kana kufonera masevhisi ekukurumidzira kana uine zviratidzo zvakakomba sekusagadzikana, kubatwa, kana kurasikirwa nekuziva.

Ndoita Sei Kana Ndikakanganwa Mushonga we NPH uye Regular Insulin?

Kana ukakanganwa mushonga, utore paunorangarira, asi chete kana zviri mukati memaawa mashoma enguva yako yenguva dzose. Usawedzere mishonga kana kutora insulin yakawedzerwa kuti "ubate", sezvo izvi zvinogona kukonzera shuga yakaderera yeropa inotyisa.

Kana zviri pedyo nemushonga wako unotevera wakatarwa, siya mushonga wakakanganwa uye uenderere mberi nechirongwa chako che nguva dzose. Tarisa shuga yako yeropa kakawanda paunokanganwa mishonga, uye bata chiremba wako kana mazinga ako akava akaoma kudzora.

Ndingamira Rini Kutora NPH uye Regular Insulin?

Usambomira kutora insulin pasina gwara rechiremba wako, sezvo izvi zvinogona kukonzera matambudziko anotyisa. Vanhu vane chirwere cheshuga type 1 vanoda insulin kwehupenyu hwavo hwese, nepo avo vane chirwere cheshuga type 2 dzimwe nguva vachigona kuderedza kana kuchinja kurapwa kwavo kwe insulin.

Chiremba wako angachinja mushonga wako we insulin kana kutonga kweshuga yako yeropa kuchivandudzika zvakanyanya nekuchinja mararamiro, kurasikirwa uremu, kana mamwe mishonga. Chero shanduko ipi zvayo kumishonga yako ye insulin inofanirwa kuitwa zvishoma nezvishoma pasi pekutariswa kwechiremba kuti uve nechokwadi chekuti shuga yako yeropa inoramba yakagadzikana.

Ndingafamba neNPH neRegular Insulin here?

Hongu, unogona kufamba ne insulin, asi kuronga kwakakodzera kwakakosha. Nguva dzose takura insulin mumutoro wako wekuzvitakura paunenge uchibhururuka, sezvo tembiricha yemutoro wakatariswa inogona kukuvadza mushonga. Uya netsamba yekurapa kubva kuchiremba wako ichitsanangura kudiwa kwako kwe insulin nezvinhu zvekushandisa.

Paka insulin yakawanda nezvinhu zvekushandisa kana paine kunonoka kana kurasikirwa nemutoro. Kana uchifamba kuyambuka nzvimbo dzenguva, shanda nemupi wako wehutano kuti uchinje chirongwa chako chejekiseni zvishoma nezvishoma. Chengeta insulin pakamuri tembiricha panguva yekufamba, uye usambofa waiisa mumotokari dzinopisa kana zuva rakananga.